Ranjala Ratnayake

ORCID: 0000-0002-5980-2070

MedicineBiochemistry, Genetics and Molecular BiologyChemistryMaterials Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “Isolation and Characterization of the Cyanobacterial Macrolide Glycoside Moorenaside, an Anti-Inflammatory Analogue of Aurisides Targeting the Keap1/Nrf2 Pathway”.

Isolation and Characterization of the Cyanobacterial Macrolide Glycoside Moorenaside, an Anti-Inflammatory Analogue of Aurisides Targeting the Keap1/Nrf2 Pathway

Journal of Natural Products(2024)10.1021/acs.jnatprod.4c00420

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0.406DataRank · unranked

8 citations

Sofia Kokkaliari, Ranjala Ratnayake, Valerie J. Paul, Hendrik Luesch, Fatma H. Al‐Awadhi

Probing a distinct druggable tubulin binding site with gatorbulins 1–7, their metabolic and physicochemical properties, and pharmacological consequences

Bioorganic & Medicinal Chemistry(2023)10.1016/j.bmc.2023.117506

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0.241DataRank · unranked

4 citations

Ranjala Ratnayake, Rafael Hortigüela, Gustavo Seabra, Michael D. Cameron, J. Fernando Dı́az +3 more

Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115546

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25 citations

Verrill M. Norwood, Ranjala Ratnayake, Hendrik Luesch, Robert W. Huigens, Nicholas G. Paciaroni

Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF‐1α Mediated Cancer Cell Viability and Vascularization

ChemBioChem(2020)10.1002/cbic.202000180

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27 citations

Sarath P. Gunasekera, Jiajia Ma, Long H. Dang, Thomas J. Carney, Valerie J. Paul +2 more

Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2021847118

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92 citations

Qi-Yin Chen, Ranjala Ratnayake, Charles S. Fermaintt, Daniel Lucena‐Agell, Francesca Bonato +9 more

Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm

Current Research in Pharmacology and Drug Discovery(2021)10.1016/j.crphar.2021.100053

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9 citations

Ranjala Ratnayake, Mengxiong Wang, Qi-Yin Chen, Kevin P. Raisch, Long H. Dang +3 more

Function‐Oriented and Modular (+/−)‐cis‐Pseudoguaianolide Synthesis: Discovery of New Nrf2 Activators and NF‐κB Inhibitors

Chemistry - A European Journal(2021)10.1002/chem.202100038

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7 citations

Ranjala Ratnayake, Henry A. M. Schares, Katherine F. M. Jones, Emily Bevan–Smith, Hendrik Luesch +3 more

Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity

ACS Infectious Diseases(2022)10.1021/acsinfecdis.2c00008

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24 citations

Laura Martin‐Sancho, Ranjala Ratnayake, Kris M. White, Laura Riva, Qi-Yin Chen +20 more

Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia

Cell Death Discovery(2022)10.1038/s41420-022-01165-4

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22 citations

Jinmai Jiang, Corey M. Perkins, Kalina R. Atanasova, Julie K. Bray, Gamze B. Bulut +11 more

Anti-Inflammatory Dysidazirine Carboxylic Acid from the Marine Cyanobacterium Caldora sp. Collected from the Reefs of Fort Lauderdale, Florida

Molecules(2022)10.3390/molecules27051717

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15 citations

Sofia Kokkaliari, Ranjala Ratnayake, Thomas Sauvage, Larissa A. H. dos Santos, Hendrik Luesch +2 more

Targeted and functional genomics approaches to the mechanism of action of lagunamide D, a mitochondrial cytotoxin from marine cyanobacteria

Biochemical Pharmacology(2023)10.1016/j.bcp.2023.115608

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10 citations

Ranjala Ratnayake, Kalina R. Atanasova, Valerie J. Paul, Hendrik Luesch, Danmeng Luo

Discovery and Anti-Inflammatory Activity of a Cyanobacterial Fatty Acid Targeting the Keap1/Nrf2 Pathway

Marine Drugs(2023)10.3390/md21110553

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9 citations

Emily F. Simon, Na Liu, Ranjala Ratnayake, Valerie J. Paul, Hendrik Luesch +1 more

Queuosine Salvage in Bartonella henselae Houston 1: A Unique Evolutionary Path

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.05.570228

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3 citations

Yifeng Yuan, Guangxin Sun, Ranjala Ratnayake, Geoffrey Hutinet, Peter C. Dedon +3 more

Epigenetic Small-Molecule Screen for Inhibition and Reversal of Acinar Ductal Metaplasia in Mouse Pancreatic Organoids

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.27.567685

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1 citations

Corey M. Perkins, Ranjala Ratnayake, Jinmai Jiang, Qi-Yin Chen, Thomas D. Schmittgen +2 more

Morphological Profiling for Drug Discovery in the Era of Deep Learning

PubMed(2023)10.48550/arxiv.2312.07899

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1 citations

Ranjala Ratnayake, Gustavo Seabra, Zhe Jiang, Ruogu Fang, Lina Cui +7 more

Morphological profiling for drug discovery in the era of deep learning

Briefings in Bioinformatics(2024)10.1093/bib/bbae284

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41 citations

Ranjala Ratnayake, Gustavo Seabra, Zhe Jiang, Ruogu Fang, Lina Cui +7 more

Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages

Microbiology and Molecular Biology Reviews(2024)10.1128/mmbr.00199-23

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38 citations

Geoffrey Hutinet, José D D Cediel-Becerra, Yifeng Yuan, Rémi Zallot, Marc G. Chevrette +5 more

Progress in the discovery and development of anticancer agents from marine cyanobacteria

Natural Product Reports(2024)10.1039/d4np00019f

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29 citations

Emma K. Ellis, Qi-Yin Chen, Ranjala Ratnayake, Hendrik Luesch

Biosynthesis of Dolastatin 10 in Marine Cyanobacteria, a Prototype for Multiple Approved Cancer Drugs

Organic Letters(2024)10.1021/acs.orglett.3c04083

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24 citations

Dipesh Dhakal, Man‐Yun Chen, Qi-Yin Chen, Sofia Kokkaliari, Nicole A. Colon Rosa +6 more

Epigenetic small-molecule screen for inhibition and reversal of acinar ductal metaplasia in mouse pancreatic organoids

Frontiers in Pharmacology(2024)10.3389/fphar.2024.1335246

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10 citations

Corey M. Perkins, Ranjala Ratnayake, Jinmai Jiang, Qi-Yin Chen, Thomas D. Schmittgen +2 more

Queuosine salvage in Bartonella henselae Houston 1: a unique evolutionary path

Microbiology(2024)10.1099/mic.0.001490

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5 citations

Yifeng Yuan, Guangxin Sun, Ranjala Ratnayake, Geoffrey Hutinet, Peter C. Dedon +3 more

Chemical Genetics in C. elegans Identifies Anticancer Mycotoxins Chaetocin and Chetomin as Potent Inducers of a Nuclear Metal Homeostasis Response

ACS Chemical Biology(2024)10.1021/acschembio.4c00131

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4 citations

A. M. Gihan K. Athapaththu, Kalina R. Atanasova, Qi-Yin Chen, Taylor J. Corcoran, Juan Piloto +5 more

Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine’s Biological Activity

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.9b01924

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48 citations

Ariana C. Brice‐Tutt, Shainnel O. Eans, Heather M. Stacy, Guqin Shi, Ranjala Ratnayake +7 more

Chemical genetics in C. elegans identifies anticancer mycotoxins chaetocin and chetomin as potent inducers of a nuclear metal homeostasis response

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.15.579914

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0 citations

A. M. Gihan K. Athapaththu, Kalina R. Atanasova, Qi-Yin Chen, Taylor J. Corcoran, Juan Piloto +5 more

Fungal Epithiodiketopiperazines Carrying α,β‐Polysulfide Bridges from Penicillium steckii YE, and Their Chemical Interconversion

ChemBioChem(2020)10.1002/cbic.202000403

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18 citations

Peilan Zhang, Ranjala Ratnayake, Guang Yang, Yi Zhang, Ran Zuo +14 more