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Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115546Source: DataRank Database

Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets is a research paper published in Bioorganic & Medicinal Chemistry (2020). On theSindex it has a DataRank of 0. It has been cited 25 times.

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Open Access25 citations

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Enrichment:Funding (6 grants)Impact (FWCI 1.04)OA: greenTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Verrill M. Norwood ORCID,Ranjala Ratnayake ORCID,Hendrik Luesch ORCID,Robert W. Huigens ORCID,Nicholas G. Paciaroni ORCID

Live enrichment

PubMed:32616180 PMC:PMC7392148 OpenAlex:https://openalex.org/W3023250970

NCI NIH HHS

Grant: R01 CA172310

NCI NIH HHS

Grant: R50 CA211487

National Institutes of Health

Grant: 3R01CA172310-04S1

Novel Targeted Anticancer Agents from Marine Cyanobacteria

National Institutes of Health

Grant: 5R50CA211487-05

Development of Complex Natural Product Libraries and Multidimensional Anticancer Screening Platforms

National Institutes of Health

American Cancer Society

FWCI

1.04

Citation Percentile

0.7%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

greenLicense: Elsevier TDM

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7392148

publisherhttps://api.elsevier.com/content/article/PII:S096808962030376X?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S096808962030376X?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bmc.2020.115546

Fields of Study

Receptor Mechanisms and SignalingChemical Synthesis and AnalysisNicotinic Acetylcholine Receptors Study0301 basic medicine0303 health sciences03 medical and health sciencesAntineoplastic AgentsBiological ProductsDose-Response Relationship, DrugHumansMolecular StructureMolecular Targeted TherapyNeoplasmsReceptors, G-Protein-CoupledStructure-Activity RelationshipYohimbine

MeSH Terms

Antineoplastic AgentsBiological ProductsDose-Response Relationship, DrugHumansNeoplasmsStructure-Activity RelationshipYohimbineMolecular StructureReceptors, G-Protein-CoupledMolecular Targeted Therapy

Keywords

G protein-coupled receptorChemistryComputational biologyNatural productDrug discoverySmall moleculeReceptorBiochemistryBiologyCancerYohimbineIndole alkaloidsGpcr Drug TargetsRing DistortionBiological ProductsDose-Response Relationship, DrugMolecular StructureAntineoplastic AgentsReceptors, G-Protein-CoupledStructure-Activity RelationshipNeoplasmsHumansMolecular Targeted Therapy

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets

FAIR Checklist

Authors (5)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)