Aaron N. Hata

Also affiliated with Massachusetts General Hospital, Global Cancer Institute, Center for Cancer Research

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

5.9Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Nature Medicine(2020)10.1038/s41591-020-0844-1

Top 4%

5.6DataRank

Top 4%819 citations

Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro +45 more

Papers

Driven by 44 papers — median percentile 73. Top paper: “A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors”.

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Nature Medicine(2020)10.1038/s41591-020-0844-1

Top 4%

5.6DataRank

Top 4%819 citations

Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro +45 more

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/761429

N/A

2.5DataRank · unranked

68 citations

Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro, Indresh Singh +44 more

Identification of optimal dosing schedules of dacomitinib and osimertinib for a phase I/II trial in advanced EGFR-mutant non-small cell lung cancer

Nature Communications(2021)10.1038/s41467-021-23912-4

N/A

1.1DataRank · unranked

34 citations

Adam J. Schoenfeld, Alex Makhnin, Yosef Y. Tobi, Yuli Wang, Heidie Frisco Cabanos +10 more

Cycling cancer persister cells arise from lineages with distinct programs

Nature(2021)10.1038/s41586-021-03796-6

N/A

0.933DataRank · unranked

502 citations

Michael Tsabar, Michael S. Cuoco, Liat Amir-Zilberstein, Jan-Christian Hütter, Bomiao Hu +18 more

Therapy-induced APOBEC3A drives evolution of persistent cancer cells

Nature(2023)10.1038/s41586-023-06303-1

N/A

0.753DataRank · unranked

150 citations

Ramin Sakhtemani, Ammal Abbasi, Naveed Nikpour, Marcello Stanzione, Sunwoo Oh +36 more

NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer

Cell Metabolism(2023)10.1016/j.cmet.2023.01.012

N/A

0.750DataRank · unranked

147 citations

Maolin Ge, Makiko Hayashi, Magdy Gohar, Cong-Hui Yao, Adriaan de Groot +22 more

Liquid biopsy epigenomic profiling for cancer subtyping

Nature Medicine(2023)10.1038/s41591-023-02605-z

N/A

0.722DataRank · unranked

122 citations

Ji-Heui Seo, Matthew P. Davidsohn, Brad Fortunato, Karl Semaan, Shahabbedin Sotudian +38 more

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

Cell(2024)10.1016/j.cell.2024.03.027

N/A

0.686DataRank · unranked

96 citations

Harrison B. Chong, Siwen Zhang, Tzu-Yi Yang, Matthew J. Lazarov, Stefan Harry +66 more

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity

Science Advances(2021)10.1126/sciadv.abf8609

N/A

0.637DataRank · unranked

69 citations

Ben A. Croker, Clarence Yapp, Gaurav N. Joshi, Johan Spetz, Cameron Fraser +26 more

BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency

Cancer Research(2020)10.1158/0008-5472.can-20-1744

N/A

0.624DataRank · unranked

63 citations

Carla P. Concepcion, Caroline G. Fahey, Hasmik Keshishian, Arjun Bhutkar, Christine F. Brainson +23 more

Genomic landscape of clinically acquired resistance alterations in patients treated with KRASG12C inhibitors

Annals of Oncology(2025)10.1016/j.annonc.2025.01.020

N/A

0.601DataRank · unranked

54 citations

Ferran Fece de la Cruz, W. Marston Linehan, Christine M. Parseghian, Jonathan Kim, Hiroyuki Matsubara +19 more

NVL-655 Is a Selective and Brain-Penetrant Inhibitor of Diverse ALK-Mutant Oncoproteins, Including Lorlatinib-Resistant Compound Mutations

Cancer Discovery(2024)10.1158/2159-8290.cd-24-0231

N/A

0.587DataRank · unranked

49 citations

Joshua C. Horan, Anupong Tangpeerachaikul, Aurélie Swalduz, Augusto Valdivia, Melissa L. Johnson +23 more

Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells

Science Translational Medicine(2022)10.1126/scitranslmed.abc7480

N/A

0.581DataRank · unranked

47 citations

Min Lu, Hazel X. Ang, Ryan S. Soderquist, Christine E. Eyler, Haley M. Hutchinson +12 more

Targeting the DNA replication stress phenotype of KRAS mutant cancer cells

Scientific Reports(2021)10.1038/s41598-021-83142-y

N/A

0.542DataRank · unranked

36 citations

O. H. Fiete Gehrisch, Marie‐Michelle Genois, Qi Liu, Shan Lü, Jong Kung +8 more

Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-0466

N/A

0.533DataRank · unranked

34 citations

Catherine B. Meador, Xintao Qiu, Ji-Heui Seo, Matthew P. Davidsohn, Hunter Savignano +20 more

GUK1 activation is a metabolic liability in lung cancer

Cell(2025)10.1016/j.cell.2025.01.024

N/A

0.449DataRank · unranked

19 citations

Kiran Kurmi, Yutong Dai, Ishita Dhiman, Shakchhi Joshi, Brandon M. Gassaway +21 more

A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma

Nature Cancer(2025)10.1038/s43018-025-01053-7

N/A

0.351DataRank · unranked

9 citations

Thinh T. Nguyen, Atharva Bhagwat, Akhil Kumar, Bruno Giotti, Benjamin Kepecs +29 more

A cellular and spatial atlas of TP53 -associated tissue remodeling in lung adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.28.546977

Top 50%

0.349DataRank

Top 50%5 citations

Benjamin Kepecs, Navin R. Mahadevan, Jason L. Weirather, Naomi R. Besson, Bruno Giotti +19 more

Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.20.473544

N/A

0.345DataRank · unranked

9 citations

Matthew Spindler, Marta Herrero Alonso, Yifang Shui, David G. Millar, David S. Johnson +3 more

LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers

Nature Communications(2025)10.1038/s41467-025-58753-y

N/A

0.345DataRank · unranked

9 citations

Mohammed U. Syed, Anahita Nimbalkar, Yi Shen, Melissa D. Vieira, Cameron Fraser +24 more

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.20.563287

N/A

0.330DataRank · unranked

8 citations

Harrison B. Chong, Siwen Zhang, Matthew J. Lazarov, Stefan Harry, Michelle Maynard +64 more

Cycling cancer persister cells arise from lineages with distinct transcriptional and metabolic programs

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.05.136358

N/A

0.312DataRank · unranked

7 citations

Michael Tsabar, Michael S. Cuoco, Elma Zaganjor, Pratiksha I. Thakore, Marcin Tabaka +9 more

Activation of APOBEC3 cytidine deaminases and endogenous retroviruses is integrated by MUC1-C in NSCLC cells

Cell Death Discovery(2025)10.1038/s41420-025-02673-9

N/A

0.292DataRank · unranked

6 citations

Shinkichi Takamori, Hideko Isozaki, Keisuke Shigeta, Chie Kikutake, Hiroki Ozawa +9 more

MUCIN 1 confers inflammatory memory of tyrosine kinase inhibitor resistance in non-small cell lung cancer

Signal Transduction and Targeted Therapy(2025)10.1038/s41392-025-02482-7

N/A

0.211DataRank · unranked

3 citations

Naoki Haratake, Atrayee Bhattacharya, Chie Kikutake, Hiroki Ozawa, Keisuke Shigeta +15 more

LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS -mutant lung cancers

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.29.510137

N/A

0.104DataRank · unranked

1 citations

Mohammed U. Syed, Anahita Nimbalkar, Yi Shen, Fraser Cameron, Zintis Inde +23 more

In vivo metabolomics identifies CD38 as an emergent vulnerability in LKB1 -mutant lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.18.537350

N/A

0.104DataRank · unranked

1 citations

David H. Peng, David Fenyö, Hao Yuan, Alfonso Lopez, Daniel Levin +26 more

Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics

Nature Communications(2022)10.1038/s41467-022-33461-z

N/A

0DataRank · unranked

20 citations

Johan Spetz, Xingping Qin, Adam Presser, Jonathan Choiniere, Chendi Li +10 more

Structural and functional analysis of lorlatinib analogs reveals roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.16.452681

N/A

0DataRank · unranked

2 citations

Ted W. Johnson, Ibiayi Dagogo‐Jack, Mari Mino–Kenudson, Theodore R. Johnson, Ping Wei +16 more

MET D1228N and D1246N are the Same Resistance Mutation in MET Exon 14 Skipping

The Oncologist(2021)10.1002/onco.13924

N/A

0DataRank · unranked

5 citations

Aaron N. Hata, Jochen K. Lennerz, Jonathan M. Tsai

Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.03.531059

N/A

0DataRank · unranked

1 citations

Juliet Allen, Troy W. Whitfield, Asaf Maoz, Sarah Reeves, José Velarde +6 more

Alginate-based 3D cancer cell culture for therapeutic response modeling

STAR Protocols(2021)10.1016/j.xpro.2021.100391

N/A

0DataRank · unranked

10 citations

Samar Ghorbanpoor, Satoshi Yoda, Xiao Pan, Giovanna Stein Crowther, Xunqin Yin +5 more

Porous Paclitaxel Mesh Reduces Local Recurrence in Patient-Derived Xenograft Resection Model

The Annals of Thoracic Surgery(2022)10.1016/j.athoracsur.2022.09.048

N/A

0DataRank · unranked

4 citations

Danielle M. Fitzgerald, Rong Liu, Jenny T. Korunes-Miller, Eliza Neal, Yin P. Hung +5 more

Unprocessed genomic uracil as a source of DNA replication stress in cancer cells

Molecular Cell(2024)10.1016/j.molcel.2024.04.004

N/A

0DataRank · unranked

40 citations

Christopher S. Nabel, Turner W. Seay, Parasvi S. Patel, Ajinkya S. Kawale, Caroline R. Crosby +7 more

Emerging Insights into Targeted Therapy-Tolerant Persister Cells in Cancer

Cancers(2021)10.3390/cancers13112666

N/A

0DataRank · unranked

192 citations

Aaron N. Hata, Heidie Frisco Cabanos

Targeting therapy-persistent residual disease

Nature Cancer(2024)10.1038/s43018-024-00819-9

N/A

0DataRank · unranked

17 citations

Lani F. Wu, Steven J. Altschuler, Aaron N. Hata, Xiaoxiao Sun

Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction

Journal of Clinical Investigation(2024)10.1172/jci169315

N/A

0DataRank · unranked

16 citations

Juliet Allen, Troy W. Whitfield, Asaf Maoz, Sarah Reeves, José Velarde +9 more

Targeting APOBECs in cancer: It’s about timing

Cancer Cell(2024)10.1016/j.ccell.2024.03.010

N/A

0DataRank · unranked

11 citations

Mani Larijani, Aaron N. Hata

Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms

Cancer Cell(2021)10.1016/j.ccell.2021.09.003

N/A

0DataRank · unranked

263 citations

Zofia Piotrowska, Patricia J. Hare, Huidong Chen, Hillary E. Mulvey, Aislinn Mayfield +23 more

Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS–MAPK Reactivation

Cancer Discovery(2021)10.1158/2159-8290.cd-21-0365

N/A

0DataRank · unranked

520 citations

W. Marston Linehan, Chendi Li, Meagan B. Ryan, Junbing Zhang, Lesli A. Kiedrowski +15 more

Investigating New Mechanisms of Acquired Resistance to Targeted Therapies: If You Hit Them Harder, Do They Get Up Differently?

Cancer Research(2020)10.1158/0008-5472.can-19-3405

N/A

0DataRank · unranked

4 citations

Aaron N. Hata, Anthony C. Faber, Konstantinos V. Floros

Screening and Validation of Molecular Targeted Radiosensitizers

International Journal of Radiation Oncology*Biology*Physics(2021)10.1016/j.ijrobp.2021.07.1694

N/A

0DataRank · unranked

21 citations

Xiao Pan, Nathalie Borgeaud, Irina Korovina, Lydia Koi, Regina K. Egan +17 more

NRF2 activation induces NADH-reductive stress providing a metabolic vulnerability in lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.31.506025

N/A

0DataRank · unranked

13 citations

Maolin Ge, Addriaan de Groot, Alexander Carlin, Magdy Gohar, Hannah Fischer +18 more

LKB1 loss rewires JNK-induced apoptotic protein dynamics through NUAKs and sensitizes KRAS-mutant NSCLC to combined KRASG12C + MCL-1 blockade

Research Square(2022)10.21203/rs.3.rs-2334763/v1

N/A

0DataRank · unranked

0 citations

Chendi Li, Mohammed U. Syed, Yi Shen, Cameron Fraser, Jian Ouyang +16 more

MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state

Cancer Gene Therapy(2022)10.1038/s41417-022-00504-y

N/A

0DataRank · unranked

19 citations

Nicholas Skiados, Fareesa Aftab, Cerena Moreno, Luis Silva, Paul Joshua Anthony Corbilla +4 more

Aaron N. Hata

Indexed papers

Top data-sharing exemplar

Papers