Sander M. Houten

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 33 papers. Top paper: “Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1”.

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

Open Biology(2022)10.1098/rsob.220179

N/A

1.4DataRank · unranked

14 citations

Susmita Khamrui, Chalada Suebsuwong, Peng‐Jen Chen, Cody Secor, Tetyana Dodatko +6 more

Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence

Cell Reports(2023)10.1016/j.celrep.2023.113371

N/A

0.470DataRank · unranked

22 citations

Jialiang Yang, Simon Koplev, Mahru C. An, Priyanka L. Patel, Robert O’Brien +16 more

Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.02.433634

N/A

0.328DataRank · unranked

5 citations

Sara Violante, Carmen Argmann, Tetyana Dodatko, D. Bhattacharya, Hongjie Chen +5 more

Dietary restriction in the long-chain acyl-CoA dehydrogenase knockout mouse

Molecular Genetics and Metabolism Reports(2021)10.1016/j.ymgmr.2021.100749

N/A

0.292DataRank · unranked

6 citations

Michel van Weeghel, Mayte Suárez‐Fariñas, Carmen Argmann, Pablo Ranea‐Robles, Ronald J. A. Wanders +5 more

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.21.109124

N/A

0DataRank · unranked

30 citations

Minami Tokuyama, Gabrielle Wei, Ruiqi Huang, Alexandra E. Livanos, Divya Jha +31 more

Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.20.913012

N/A

0DataRank · unranked

2 citations

Susmita Khamrui, Hui Wang, Chalada Suebsuwong, Natalia S. Nemeria, Khoi Huynh +14 more

Integrative Analysis of the Inflammatory Bowel Disease Serum Metabolome Improves Our Understanding of Genetic Etiology and Points to Novel Putative Therapeutic Targets

Gastroenterology(2021)10.1053/j.gastro.2021.11.015

N/A

0DataRank · unranked

89 citations

Sander M. Houten, Roman Kosoy, Ruiqi Huang, Frédéric M. Vaz, Ruixue Hou +24 more

An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease

Nature Communications(2021)10.1038/s41467-020-20750-8

N/A

0DataRank · unranked

63 citations

William Barrington, Daniel M. Jordan, Noam D. Beckmann, Carmen Argmann, Sander M. Houten +21 more

Toward an Understanding of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxoacid Dehydrogenase Complexes

Life(2021)10.3390/life11050407

N/A

0DataRank · unranked

22 citations

Xu Zhang, João Leandro, Jieyu Zhou, Luying Yang, Sander M. Houten +2 more

Leveraging health systems data to characterize a large effect variant conferring risk for liver disease in Puerto Ricans

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.09.016

N/A

0DataRank · unranked

14 citations

Stephanie Rutledge, Tetyana Dodatko, Sinéad Cullina, Michael C. Turchin, Sumita Kohli +7 more

Toward an Understanding Of the Structural and Mechanistic Aspects of Protein-Protein Interactions in 2-Oxo Acid Dehydrogenase Complexes

Preprints.org(2021)10.20944/preprints202104.0339.v1

N/A

0DataRank · unranked

7 citations

Xu Zhang, João Leandro, Jieyu Zhou, Luying Yang, Sander M. Houten +2 more

The peroxisomal transporter ABCD3 plays a major role in dicarboxylic fatty acid metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.26.452046

N/A

0DataRank · unranked

2 citations

Hongjie Chen, Brandon Stauffer, Chunli Yu, D. Bhattacharya, Scott L. Friedman +3 more

PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.12.451352

N/A

0DataRank · unranked

1 citations

David Sachs, Bhavana Shewale, David M. Gonzalez, Priyanka Dhanan-Krishnan, Denis Torre +21 more

A mitochondrial long-chain fatty acid oxidation defect leads to uncharged tRNA accumulation and activation of the integrated stress response in the mouse heart

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.13.443905

N/A

0DataRank · unranked

0 citations

Natalya N. Pavlova, Aaron Bender, Andrea S. Pereyra, Jessica M. Ellis, Brandon Stauffer +6 more

PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

Cell stem cell(2022)10.1016/j.stem.2022.02.011

N/A

0DataRank · unranked

98 citations

David Sachs, Bhavana Shewale, David M. Gonzalez, Priyanka Dhanan-Krishnan, Denis Torre +21 more

Functional Versatility of the Human 2-Oxoadipate Dehydrogenase in the L-Lysine Degradation Pathway toward Its Non-Cognate Substrate 2-Oxopimelic Acid

International Journal of Molecular Sciences(2022)10.3390/ijms23158213

N/A

0DataRank · unranked

12 citations

Bálint Nagy, Roberto Sánchez, Xu Zhang, João Leandro, Attila Ambrus +3 more

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.20.492856

N/A

0DataRank · unranked

1 citations

Susmita Khamrui, Chalada Suebsuwong, Peng‐Jen Chen, Cody Secor, Tetyana Dodatko +6 more

Acyl-CoA dehydrogenase substrate promiscuity limits the potential for development of substrate reduction therapy in disorders of valine and isoleucine metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.22.517273

N/A

0DataRank · unranked

0 citations

Tetyana Dodatko, William Dwyer, Hongjie Chen, Brandon Stauffer, Robert J. DeVita +4 more

The biochemistry and physiology of long-chain dicarboxylic acid metabolism

Biochemical Journal(2023)10.1042/bcj20230041

N/A

0DataRank · unranked

62 citations

Sander M. Houten, Pablo Ranea‐Robles

Acyl‐CoA dehydrogenase substrate promiscuity: Challenges and opportunities for development of substrate reduction therapy in disorders of valine and isoleucine metabolism

Journal of Inherited Metabolic Disease(2023)10.1002/jimd.12642

N/A

0DataRank · unranked

8 citations

Tetyana Dodatko, William Dwyer, Sara Violante, Hongjie Chen, Brandon Stauffer +6 more

A case of hyperlysinemia identified by urine newborn screening

JIMD Reports(2023)10.1002/jmd2.12399

N/A

0DataRank · unranked

3 citations

Christiane Auray‐Blais, Bruno Maranda, Amanda Sabovic, Robert J. DeVita, Michael B. Lazarus +2 more

Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1

ACS Chemical Biology(2024)10.1021/acschembio.4c00204

N/A

0DataRank · unranked

4 citations

Susmita Khamrui, Tetyana Dodatko, João Leandro, Amanda Sabovic, Sara Violante +7 more

Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.07.578422

N/A

0DataRank · unranked

0 citations

Tetyana Dodatko, Ruoxi Wu, João Leandro, Amanda Sabovic, Sara Violante +7 more

Vitamin K as an add-on therapy in pyridoxine-dependent epilepsy

Molecular Therapy(2025)10.1016/j.ymthe.2025.03.009

N/A

0DataRank · unranked

1 citations

Sander M. Houten

A cold-inducible phospholipid—protein interaction in brown fat mitochondria optimizes thermogenic capacity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.15.654206

N/A

0DataRank · unranked

1 citations

Marc J. Tol, Christian Rocha-Roa, Matthew J. Jellinek, Liujuan Cui, Aaron Bender +23 more

Odd-chain dicarboxylic acid feeding recapitulates the biochemical phenotype of glutaric aciduria type 1 in mice

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.13.637994

N/A

0DataRank · unranked

0 citations

Yuxun Zhang, Sivakama S. Bharathi, Abigail Hernandez, Tetyana Dodatko, Joanna Bons +6 more

A multiomic network approach uncovers disease modifying mechanisms of inborn errors of metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.19.639093

N/A

0DataRank · unranked

0 citations

Pablo Ranea‐Robles, Evan G. Williams, Mina Mirzaian, J. Alexander Heimel, Christiaan N. Levelt +7 more

A Multiomic Network Approach to Uncover Disease Modifying Mechanisms of Inborn Errors of Metabolism

Journal of Inherited Metabolic Disease(2025)10.1002/jimd.70045

N/A

0DataRank · unranked

0 citations

Pablo Ranea‐Robles, Evan G. Williams, Mina Mirzaian, J. Alexander Heimel, Christiaan N. Levelt +7 more

Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2–related Disease

Gastroenterology(2020)10.1053/j.gastro.2020.09.029

N/A

0DataRank · unranked

131 citations

Minami Tokuyama, Gabrielle Wei, Ruiqi Huang, Alexandra E. Livanos, Divya Jha +33 more

Odd‐Chain Dicarboxylic Acid Feeding Produces a Glutaric Aciduria Type 1–Like Metabolic Signature in Mice

The FASEB Journal(2025)10.1096/fj.202502381r

N/A

0DataRank · unranked

0 citations

Yuxun Zhang, Sivakama S. Bharathi, Abigail Hernandez, Tetyana Dodatko, Joanna Bons +7 more

Structure–function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.012761

N/A

0DataRank · unranked

10 citations

Natalia S. Nemeria, João Leandro, Sander M. Houten, Michael B. Lazarus, Gary J. Gerfen +6 more

DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo

Human Molecular Genetics(2020)10.1093/hmg/ddaa037

N/A

0DataRank · unranked

38 citations

Tetyana Dodatko, Jan Aten, Natalia S. Nemeria, Xu Zhang, Frank Jordan +6 more

NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart

Frontiers in Immunology(2020)10.3389/fimmu.2020.591815

N/A

0DataRank · unranked

26 citations

Yang Xiao, Rianne Nederlof, Diane Bakker, Pengbo Zhang, Stephen E. Girardin +7 more