Matthew J. Bown

Also affiliated with Glenfield Hospital, University Hospitals of Leicester NHS Trust, NIHR Leicester Cardiovascular Biomedical Research Unit, NIHR Leicester Biomedical Research Centre

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.1Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Papers

Driven by 23 papers — median percentile 76. Top paper: “A genomic mutational constraint map using variation in 76,156 human genomes”.

A genomic mutational constraint map using variation in 76,156 human genomes

Nature(2023)10.1038/s41586-023-06045-0

N/A

9.6DataRank · unranked

1369 citations

Laurent C. Francioli, Julia K. Goodrich, Ryan L. Collins, Masahiro Kanai, Qingbo S. Wang +95 more

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Nature Communications(2020)10.1038/s41467-019-12438-5

N/A

5.6DataRank · unranked

143 citations

James Zou, Beryl B. Cummings, Jessica Alföldi, Laurent C. Francioli, Laura D. Gauthier +174 more

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Nature Communications(2020)10.1038/s41467-019-10717-9

N/A

5.2DataRank · unranked

191 citations

Konrad J. Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J. Smith, D. Gareth Evans +181 more

The effect of LRRK2 loss-of-function variants in humans

Nature Medicine(2020)10.1038/s41591-020-0893-5

N/A

4.9DataRank · unranked

114 citations

Irina M. Armean, Aaron Kleinman, Jamie L. Marshall, Eric V. Minikel, Julia K. Goodrich +214 more

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

Nature Communications(2018)10.1038/s41467-018-03911-8

N/A

3.1DataRank · unranked

104 citations

Amit V. Khera, Mark Chaffin, Derek Klarin, Pradeep Natarajan, Krishna Aragam +43 more

Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Nature Genetics(2023)10.1038/s41588-023-01510-y

N/A

1.6DataRank · unranked

100 citations

Derek Klarin, Michael G. Levin, Joshua M. Spin, Yae Hyun Rhee, Alicia Deng +92 more

The mutational constraint spectrum quantified from variation in 141,456 humans

Nature(2020)10.1038/s41586-020-2308-7

N/A

1.4DataRank · unranked

9958 citations

Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo S. Wang +187 more

Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

eLife(2021)10.7554/elife.72452

N/A

1.3DataRank · unranked

44 citations

Jessica Tyrrell, E. Louise Thomas, Matthew J. Bown, Andrew R. Wood, Robin N. Beaumont +19 more

Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.11.021

N/A

1.3DataRank · unranked

70 citations

Peter Dornbos, Mark Chaffin, Dajiang J. Liu, Minxian Wang, Margaret Sunitha Selvaraj +95 more

Transcript expression-aware annotation improves rare variant interpretation

Nature(2020)10.1038/s41586-020-2329-2

N/A

0.796DataRank · unranked

201 citations

Konrad J. Karczewski, Ditte Demontis, Eleanor G. Seaby, Nicholas A. Watts, Moriel Singer-Berk +177 more

Evaluating drug targets through human loss-of-function genetic variation

Nature(2020)10.1038/s41586-020-2267-z

N/A

0.779DataRank · unranked

179 citations

Konrad J. Karczewski, Hilary C. Martin, Beryl B. Cummings, Nicola Whiffin, Daniel R. Rhodes +150 more

Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.22.423783

N/A

0.534DataRank · unranked

11 citations

Peter Dornbos, Mark Chaffin, Dajiang J. Liu, Minxian X. Wang, Margaret Sunitha Selvaraj +95 more

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Stroke(2023)10.1161/strokeaha.122.040715

N/A

0.520DataRank · unranked

31 citations

Jos P. Kanning, Gad Abraham, Amy E. Martinsen, Bendik Slagsvold Winsvold, John‐Anker Zwart +95 more

Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database

Nature Communications(2025)10.1038/s41467-025-61698-x

Top 44%

0.417DataRank

Top 44%14 citations

Moriel Singer‐Berk, Sarah L. Stenton, Julia K. Goodrich, Michael W. Wilson, Jonah Einson +95 more

A comparison of arterial spin labelling with catheter angiography in evaluating arteriovenous malformations: a systematic review

British Journal of Radiology(2020)10.1259/bjr.20190830

N/A

0.292DataRank · unranked

6 citations

Deyashini Mukherjee, Jonathan Delf, Matthew J. Bown, Neghal Kandiyil, Sanjeev Ramachandran

Network reconstruction for trans acting genetic loci using multi-omics data and prior information

Genome Medicine(2022)10.1186/s13073-022-01124-9

N/A

0.269DataRank · unranked

5 citations

Ashis Saha, Melanie Waldenberger, Sonja Kunze, Simone Wahl, Martina Müller-Nurasyid +14 more

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.

Apollo (University of Cambridge)(2020)10.17863/cam.52580

N/A

0DataRank · unranked

0 citations

Mary E. Haas, Amit V. Khera, Krishna G. Aragam, Mark Chaffin, Derek Klarin +37 more

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

PLoS Genetics(2020)10.1371/journal.pgen.1008629

N/A

0DataRank · unranked

169 citations

Mary E. Haas, Amit V. Khera, Krishna G. Aragam, Mark Chaffin, Derek Klarin +37 more

Genetic risk score for intracranial aneurysms to predict aneurysmal subarachnoid hemorrhage and identify associations with patient characteristics

medRxiv(2022)10.1101/2022.04.29.22274404

N/A

0DataRank · unranked

0 citations

Jos P. Kanning, Gad Abraham, Amy E. Martinsen, Bendik S Winsvold, John‐Anker Zwart +19 more

Editor's Choice – Infra-Renal Aortic Diameter and Cardiovascular Risk: Making Better Use of Abdominal Aortic Aneurysm Screening Outcomes

European Journal of Vascular and Endovascular Surgery(2021)10.1016/j.ejvs.2021.03.013

N/A

0DataRank · unranked

39 citations

Athanasios Saratzis, John R. Thompson, Emmanuel Katsogridakis, Matthew J. Bown, David Sidloff

Using genetics to uncouple higher adiposity from its adverse metabolic effects and understand its role in metabolic and non-metabolic disease.

Research Square(2021)10.21203/rs.3.rs-537397/v2

N/A

0DataRank · unranked

0 citations

Jessica Tyrrell, E. Louise Thomas, Matthew J. Bown, Andrew R. Wood, Robin N. Beaumont +18 more

Multimodal Structural Analysis of the Human Aorta: From Valve to Bifurcation

European Journal of Vascular and Endovascular Surgery(2022)10.1016/j.ejvs.2022.02.005

N/A

0DataRank · unranked

18 citations

Liam Musto, Charley Budgeon, Guy N. Rutty, Mike Biggs, Athanasios Saratzis +5 more

Matthew J. Bown

Indexed papers

Top data-sharing exemplar

Papers