Julia F. Alterman

Also affiliated with University of Massachusetts Chan Medical School

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep”.

Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep

JCI Insight(2021)10.1172/jci.insight.152203

N/A

0.510DataRank · unranked

29 citations

Bruno M.D.C. Godinho, Julia F. Alterman, Andrew H. Coles, Matthew Hassler, Dimas Echeverria +13 more

A combinatorial approach for achieving CNS-selective RNAi

Nucleic Acids Research(2024)10.1093/nar/gkae100

N/A

0.385DataRank · unranked

12 citations

Bruno M.D.C. Godinho, Dimas Echeverria, Matthew Hassler, Lorenc Vangjeli, Jacquelyn Sousa +8 more

Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity

Nucleic Acids Research(2021)10.1093/nar/gkab1126

N/A

0DataRank · unranked

20 citations

Samuel Hildebrand, Sarah M. Davis, Rachael Miller, Faith Conroy, Ellen Sapp +10 more

Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1

Molecular Therapy — Nucleic Acids(2022)10.1016/j.omtn.2022.06.009

N/A

0DataRank · unranked

55 citations

Vignesh Hariharan, Agnes S. Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa +7 more

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models

Nature Communications(2022)10.1038/s41467-022-33061-x

N/A

0DataRank · unranked

49 citations

Rachael Miller, Julia F. Alterman, Matthew Hassler, Dimas Echeverria, Bruno M.D.C. Godinho +12 more

PK-modifying anchors significantly alter clearance kinetics, tissue distribution, and efficacy of therapeutics siRNAs

Molecular Therapy — Nucleic Acids(2022)10.1016/j.omtn.2022.06.005

N/A

0DataRank · unranked

27 citations

Emily G. Knox, Samuel Hildebrand, James W. Gilbert, Dimas Echeverria, Zachary Kennedy +9 more

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in vivo in CNS

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.29.498088

N/A

0DataRank · unranked

0 citations

Rachael Miller, Julia F. Alterman, Matthew Hassler, Dimas Echeverria, Bruno M.D.C. Godinho +12 more

Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin

Nature Communications(2023)10.1038/s41467-023-42714-4

N/A

0DataRank · unranked

50 citations

Hassan H. Fakih, Mohammad Zain UI Abideen, Samuel Hildebrand, Khashayar Afshari, Katherine Y. Gross +31 more

Single intravitreal administration of a tetravalent siRNA exhibits robust and efficient gene silencing in mouse and pig photoreceptors

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.102088

N/A

0DataRank · unranked

16 citations

Jillian Caiazzi, Annabelle Biscans, Julia F. Alterman, Dimas Echeverria, Nicholas McHugh +7 more

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.26.542506

N/A

0DataRank · unranked

7 citations

Vignesh Hariharan, Jillian Caiazzi, Rachael Miller, Chantal Furguson, Ellen Sapp +18 more

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

Research Square(2023)10.21203/rs.3.rs-2987323/v1

N/A

0DataRank · unranked

4 citations

Jillian Caiazzi, Rachael Miller, Chantal Ferguson, Ellen Sapp, Hassan Fakih +18 more

A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.19.572404

N/A

0DataRank · unranked

4 citations

Qi Tang, Sam Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria +11 more

Single intravitreal administration of a tetravalent siRNA exhibits robust and efficient gene silencing in rodent and swine photoreceptors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.20.558641

N/A

0DataRank · unranked

0 citations

Jillian Caiazzi, Annabelle Biscans, Julia F. Alterman, Dimas Echeverria, Nicholas McHugh +7 more

A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system

Nucleic Acids Research(2024)10.1093/nar/gkae368

N/A

0DataRank · unranked

26 citations

Qi Tang, Samuel Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria +11 more

Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102359

N/A

0DataRank · unranked

20 citations

Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato +10 more

Multispecies-targeting siRNAs for the modulation of JAK1 in the skin

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102117

N/A

0DataRank · unranked

18 citations

Katherine Y. Gross, Hassan H. Fakih, Samuel O. Jackson, Mohammad Zain UI Abideen, Kathryn Monopoli +7 more

Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.06.597639

N/A

0DataRank · unranked

1 citations

Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato +10 more

Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy

Nucleic Acids Research(2025)10.1093/nar/gkaf479

N/A

0DataRank · unranked

15 citations

Samuel Hildebrand, Hannah J. MacMillan, Kathryn Monopoli, Julianna Buchwald, Jacquelyn Sousa +20 more

Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs

Nucleic Acids Research(2025)10.1093/nar/gkaf1374

N/A

0DataRank · unranked

1 citations

Clemens Lochmann, Rosemary Gagnon, Ashley Summers, Jillian Caiazzi, Julianna Buchwald +15 more

A Therapeutic Small-Interfering RNA Potentiates Janus Kinase 1 Modulation for the Treatment of Dog Inflammatory Diseases

ACS Pharmacology & Translational Science(2025)10.1021/acsptsci.4c00594

N/A

0DataRank · unranked

0 citations

Hassan H. Fakih, Katherine Y. Gross, Sarah J. Winter, Brianna Bramato, Ümmügülsüm Yıldız-Altay +13 more

2′-O-Methyl at 20-mer Guide Strand 3′ Termini May Negatively Affect Target Silencing Activity of Fully Chemically Modified siRNA

Molecular Therapy — Nucleic Acids(2020)10.1016/j.omtn.2020.05.010

N/A

0DataRank · unranked

21 citations

Jacquelyn Sousa, Lorenc Vangjeli, Matthew Hassler, Dimas Echeverria, Emily G. Knox +4 more

Presence of phosphodiester backbone, but not nucleobases, in the guide’s 3′ terminal region is necessary for RISC loading and target cleavage in vitro and in vivo

Nucleic Acids Research(2025)10.1093/nar/gkaf1438

N/A

0DataRank · unranked

0 citations

Raymond Furgal, Vella M Ross, Eric Luu, Katherine Y. Gross, Vignesh Hariharan +12 more

An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis

Molecular Therapy(2021)10.1016/j.ymthe.2021.11.007

N/A

0DataRank · unranked

46 citations

Nicole Wetoska, Mark Kelly, Dimas Echeverria, Kyounghee Min, Lawrence M. Lifshitz +13 more