Ophir D. Klein

Also affiliated with University of California, San Francisco

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.677Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses

Scientific Data(2022)10.1038/s41597-022-01338-x

Top 43%

0.429DataRank

Top 43%13 citations

Marta Vidal‐García, Wei Liu, Amanda Neves, Lucas Lo Vercio, Rebecca M. Green +31 more

Papers

Driven by 63 papers — median percentile 48. Top paper: “Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth”.

Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth

Nature Communications(2020)10.1038/s41467-020-18512-7

N/A

0.834DataRank · unranked

259 citations

Ruslan Soldatov, Maria Eleni Kastriti, Tatiana Chontorotzea, Anna Nele Herdina, Julian Petersen +21 more

Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral

International Journal of Oral Science(2023)10.1038/s41368-023-00257-w

N/A

0.782DataRank · unranked

21 citations

Victoria Cooley, Eun‐Jung Kim, Shujin Li, Jong‐Min Lee, Dina Sheyfer +5 more

Engineering synthetic morphogen systems that can program multicellular patterning

Science(2020)10.1126/science.abc0033

N/A

0.761DataRank · unranked

159 citations

Wesley L. McKeithan, Teemu J. Häkkinen, Maria del Pilar Lopez Pazmino, Ophir D. Klein, Wendell A. Lim +1 more

Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains

Nature Cell Biology(2024)10.1038/s41556-023-01337-z

N/A

0.665DataRank · unranked

83 citations

Petr Kašpárek, Brisa Palikuqi, Sara Viragova, Laura Weichselbaum, Christopher S. McGinnis +14 more

Transit-Amplifying Cells Coordinate Changes in Intestinal Epithelial Cell-Type Composition

Developmental Cell(2021)10.1016/j.devcel.2020.12.020

N/A

0.644DataRank · unranked

72 citations

Ina W. Chen, Jake M. Bieber, Veronica Steri, Coralie Trentesaux, Byron Hann +4 more

Harnessing synthetic biology to engineer organoids and tissues

Cell stem cell(2023)10.1016/j.stem.2022.12.013

N/A

0.633DataRank · unranked

67 citations

Toshimichi Yamada, Ophir D. Klein, Wendell A. Lim, Coralie Trentesaux

Application of full-genome analysis to diagnose rare monogenic disorders

npj Genomic Medicine(2021)10.1038/s41525-021-00241-5

N/A

0.598DataRank · unranked

53 citations

Monica Penon‐Portmann, K. Wong, Michal Levy‐Sakin, Michelle Verghese, Anne Slavotinek +15 more

Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage

Journal of Clinical Investigation(2022)10.1172/jci154993

N/A

0.538DataRank · unranked

35 citations

Elvira Mennillo, Jared L. Bain, Zhongmei Li, Xiaofei Sun, Kimberly M. Ly +15 more

Synthetic organizer cells guide development via spatial and biochemical instructions

Cell(2024)10.1016/j.cell.2024.11.017

N/A

0.529DataRank · unranked

33 citations

Coralie Trentesaux, Jonathan M. Brunger, Yini Xiao, Adam J. Stevens, Iain Martyn +8 more

EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids

JCI Insight(2023)10.1172/jci.insight.165566

N/A

0.529DataRank · unranked

33 citations

Emily M. Holloway, Caden W. Sweet, Yu-Hwai Tsai, Angeline Wu, Abigail Vallie +17 more

Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy

Cancer Discovery(2024)10.1158/2159-8290.cd-23-1459

N/A

0.483DataRank · unranked

24 citations

Martha A. Cady, Calixto‐Hope G. Lucas, Hinda Najem, Joanna J. Phillips, Brisa Palikuqi +18 more

A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling

Cell stem cell(2023)10.1016/j.stem.2022.12.008

N/A

0.477DataRank · unranked

23 citations

Tomáš Wald, Efren Reyes, Aaron Gallagher, Julia Schanin, Stephanie Vlachos +7 more

YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution

Nature Communications(2025)10.1038/s41467-024-55660-6

N/A

0.449DataRank · unranked

19 citations

Sydney I. Ramirez, Lauren Clubb, Kuniaki Sato, Valeria Burghi, Thomas S. Hoang +18 more

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses

Scientific Data(2022)10.1038/s41597-022-01338-x

Top 43%

0.429DataRank

Top 43%13 citations

Marta Vidal‐García, Wei Liu, Amanda Neves, Lucas Lo Vercio, Rebecca M. Green +31 more

Engineered epithelial curvature controls Paneth cell localization in intestinal organoids

Cell Biomaterials(2025)10.1016/j.celbio.2025.100046

N/A

0.416DataRank · unranked

15 citations

Alex Khang, Kaustav Bera, Delaney L. McNally, Michael R. Blatchley, Aaron Gallagher +5 more

Comparing 2D and 3D representations for face-based genetic syndrome diagnosis

European Journal of Human Genetics(2023)10.1038/s41431-023-01308-w

N/A

0.373DataRank · unranked

11 citations

Matthias Wilms, J. David Aponte, David C. Katz, Ophir D. Klein, François P. Bernier +4 more

Precise modulation of transcription factor levels reveals drivers of dosage sensitivity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.13.495964

N/A

0.312DataRank · unranked

7 citations

Seungsoo Kim, Hanne Hoskens, Harold Matthews, Richard A. Spritz, Ophir D. Klein +6 more

Detecting 3D syndromic faces as outliers using unsupervised normalizing flow models

Artificial Intelligence in Medicine(2022)10.1016/j.artmed.2022.102425

N/A

0.312DataRank · unranked

7 citations

Matthias Wilms, J. David Aponte, David C. Katz, Ophir D. Klein, François P. Bernier +4 more

MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.11.468142

Top 60%

0.248DataRank

Top 60%4 citations

Marta Vidal‐García, Wei Liu, Amanda Neves, Lucas Lo Vercio, Rebecca M. Green +31 more

YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution

Research Square(2023)10.21203/rs.3.rs-3426301/v1

N/A

0.241DataRank · unranked

4 citations

Farhoud Faraji, Sydney I. Ramirez, Lauren Clubb, Kuniaki Sato, Paola Anguiano Quiroz +15 more

Privacy, bias and the clinical use of facial recognition technology: A survey of genetics professionals

American Journal of Medical Genetics Part C Seminars in Medical Genetics(2023)10.1002/ajmg.c.32035

N/A

0.165DataRank · unranked

2 citations

Janice Light, Julia E. H. Brown, W. John Boscardin, Benedikt Hallgrímsson, Ophir D. Klein +1 more

Multi-Scale Part-Based Syndrome Classification of 3D Facial Images

IEEE Access(2022)10.1109/access.2022.3153357

N/A

0DataRank · unranked

12 citations

Harold Matthews, Nele Nauwelaers, Michiel Vanneste, Shunwang Gong, Giorgos Bouritsas +9 more

Refining nosology by modelling variation among facial phenotypes: the RASopathies

Journal of Medical Genetics(2022)10.1136/jmedgenet-2021-108366

N/A

0DataRank · unranked

10 citations

Michiel Vanneste, Kaitlin Katsura, David Aponte, Michael A. Patton, Peter Hammond +7 more

Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.08.479995

N/A

0DataRank · unranked

5 citations

Jérémie Rispal, Deedepya Vaka, Dario Boffelli, Ophir D. Klein, Brisa Palikuqi

A 3D Clinical Face Phenotype Space of Genetic Syndromes using a Triplet-Based Singular Geometric Autoencoder

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.27.521999

N/A

0DataRank · unranked

5 citations

Eduarda Caldeira, Harold Matthews, Michiel Vanneste, Nele Nauwelaers, Meng Yuan +11 more

Precise modulation of transcription factor levels identifies features underlying dosage sensitivity

Nature Genetics(2023)10.1038/s41588-023-01366-2

N/A

0DataRank · unranked

140 citations

Seungsoo Kim, Hanne Hoskens, Harold Matthews, Richard A. Spritz, Ophir D. Klein +6 more

Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis

Journal of Clinical Investigation(2023)10.1172/jci163591

N/A

0DataRank · unranked

33 citations

David Castillo‐Azofeifa, Jérémie Rispal, Tomáš Wald, Rachel K. Zwick, Brisa Palikuqi +8 more

Intracellular pH dynamics regulates intestinal stem cell lineage specification

Nature Communications(2023)10.1038/s41467-023-39312-9

N/A

0DataRank · unranked

32 citations

Efren Reyes, David Castillo‐Azofeifa, Ophir D. Klein, Todd Nystul, Diane L. Barber +1 more

Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.20.558726

N/A

0DataRank · unranked

9 citations

Petr Kašpárek, Brisa Palikuqi, Sara Viragova, Laura Weichselbaum, Christopher S. McGinnis +14 more

A Suite of Mouse Reagents for Studying Amelogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.30.534992

N/A

0DataRank · unranked

3 citations

Adya Verma, Victoria Cooley, Pauline Marangoni, Oscar Cazares, Amnon Sharir +8 more

Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.07.570544

N/A

0DataRank · unranked

3 citations

Hanne Hoskens, Seppe Goovaerts, Harold Matthews, J. David Aponte, Joanne B. Cole +11 more

Vole genomics links determinate and indeterminate growth of teeth

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.18.572015

N/A

0DataRank · unranked

0 citations

Andrew B. Song, Emily T. Cohen, Muspika Akter, Rishi Das Roy, Outi Hallikas +6 more

Patterning and folding of intestinal villi by active mesenchymal dewetting

Cell(2024)10.1016/j.cell.2024.04.039

N/A

0DataRank · unranked

88 citations

Teemu J. Häkkinen, Hikaru Miyazaki, Vasudha Srivastava, Emilie Barruet, Christopher S. McGinnis +14 more

Activation of fetal-like molecular programs during regeneration in the intestine and beyond

Cell stem cell(2024)10.1016/j.stem.2024.05.009

N/A

0DataRank · unranked

70 citations

Dong Li, Ophir D. Klein, Sara Viragova

Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population

Nature Communications(2024)10.1038/s41467-024-54839-1

N/A

0DataRank · unranked

9 citations

Hanne Hoskens, Seppe Goovaerts, Harold Matthews, Jay Devine, J. David Aponte +12 more

An interactive atlas of three-dimensional syndromic facial morphology

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2023.11.011

N/A

0DataRank · unranked

8 citations

Jordan J. Bannister, Hanne Hoskens, Harold Matthews, Kaitlin Katsura, Cassidy Da Silva +10 more

Bank vole genomics links determinate and indeterminate growth of teeth

BMC Genomics(2024)10.1186/s12864-024-10901-2

N/A

0DataRank · unranked

3 citations

Andrew B. Song, Emily T. Cohen, Muspika Akter, Rishi Das Roy, Outi Hallikas +6 more

A 3D Clinical Face Phenotype Space of Genetic Syndromes Using a Triplet-Based Singular Geometric Autoencoder

IEEE Access(2024)10.1109/access.2024.3524428

N/A

0DataRank · unranked

1 citations

Eduarda Caldeira, Harold Matthews, Michiel Vanneste, Nele Nauwelaers, Meng Yuan +10 more

Stress relaxing granular bioprinting materials enable complex and uniform organoid self-organization

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.01.578324

N/A

0DataRank · unranked

5 citations

Michelle W.L. Khoo, Vasudha Srivastava, Sara Viragova, Honesty Kim, Kavita Parekh +19 more

IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

Cell(2025)10.1016/j.cell.2025.08.017

N/A

0DataRank · unranked

19 citations

Sara Viragova, Satoshi Koga, Meizi Liu, Claire E. O’Leary, Roberto R. Ricardo-Gonzalez +9 more

Partially differentiated ileal and distal-colonic human F508del-cystic fibrosis-enteroids secrete fluid in response to forskolin and linaclotide

iScience(2025)10.1016/j.isci.2025.112453

N/A

0DataRank · unranked

4 citations

Zixin Zhang, Hugo R. de Jonge, Ruxian Lin, Huimin Yu, Rafiq Sarker +7 more

Lgr5+ telocytes are a signaling source at the intestinal villus tip

Nature Communications(2020)10.1038/s41467-020-15714-x

N/A

0DataRank · unranked

161 citations

Hassan Massalha, Rachel K. Zwick, Andreas E. Moor, David Castillo‐Azofeifa, Milena Rozenberg +12 more

Advancing Genotype-Phenotype Analysis through 3D Facial Morphometry: Insights from Cri-du-Chat Syndrome

medRxiv(2025)10.1101/2025.06.01.25327945

N/A

0DataRank · unranked

0 citations

Harold Matthews, Yoeri Sleyp, Peter Hammond, Mark D. Shriver, Seth M. Weinberg +9 more

Molecular and cellular mechanisms of tooth development, homeostasis and repair

Development(2020)10.1242/dev.184754

N/A

0DataRank · unranked

259 citations

Ophir D. Klein, Tingsheng Yu

Automated syndrome diagnosis by three-dimensional facial imaging

Genetics in Medicine(2020)10.1038/s41436-020-0845-y

N/A

0DataRank · unranked

106 citations

J. David Aponte, David C. Katz, Jordan J. Bannister, Sheri L. Riccardi, Nick Mahasuwan +33 more

KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice

JCI Insight(2020)10.1172/jci.insight.140495

N/A

0DataRank · unranked

32 citations

Pedro A. Pérez–Mancera, Tannie Q. Huang, Jangkyung Kim, Joaquím Grego‐Bessa, Maria del pilar Alzamora +15 more

Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium

Cell Reports(2020)10.1016/j.celrep.2020.108246

N/A

0DataRank · unranked

11 citations

Ruolan Deng, Huanyang You, Yishu Xu, Christopher L. Antos, Jianlong Sun +3 more

From gut to glutes: The critical role of niche signals in the maintenance and renewal of adult stem cells

Current Opinion in Cell Biology(2020)10.1016/j.ceb.2020.01.004

N/A

0DataRank · unranked

13 citations

Katharine Striedinger, Jason H. Pomerantz, Ophir D. Klein, Coralie Trentesaux

Tools and Concepts for Interrogating and Defining Cellular Identity

Cell stem cell(2020)10.1016/j.stem.2020.03.015

N/A

0DataRank · unranked

39 citations

David Castillo‐Azofeifa, Ophir D. Klein, Kara L. McKinley

Fully Automatic Landmarking of Syndromic 3D Facial Surface Scans Using 2D Images

Sensors(2020)10.3390/s20113171

N/A

0DataRank · unranked

35 citations

Sebastian Crites, J. David Aponte, David C. Katz, Matthias Wilms, Ophir D. Klein +5 more

FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling

BMC Biology(2020)10.1186/s12915-020-00813-4

N/A

0DataRank · unranked

28 citations

Ye Tian, Lu Han, Chao Liu, Tian‐Yu Sun, Ling Li +13 more

Application of Full Genome Analysis to Diagnose Rare Monogenic Disorders

medRxiv(2020)10.1101/2020.10.22.20216531

N/A

0DataRank · unranked

9 citations

Monica Penon‐Portmann, K. Wong, Michal Levy‐Sakin, Michelle Verghese, Anne Slavotinek +15 more

Inflation-collapse dynamics drive patterning and morphogenesis in intestinal organoids

Cell stem cell(2021)10.1016/j.stem.2021.04.002

N/A

0DataRank · unranked

91 citations

Hailey M. Cambra, Tomáš Wald, Samantha Keough Jalbert, Diana M. Abraham, Ophir D. Klein +2 more

Large-scale open-source three-dimensional growth curves for clinical facial assessment and objective description of facial dysmorphism

Scientific Reports(2021)10.1038/s41598-021-91465-z

N/A

0DataRank · unranked

42 citations

R. Palmer, Gareth Baynam, Oliver Quarrell, Ophir D. Klein, Richard A. Spritz +10 more

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model

Disease Models & Mechanisms(2021)10.1242/dmm.049166

N/A

0DataRank · unranked

26 citations

Alice F. Goodwin, Yoshiko Maeda, Ophir D. Klein, Katherine A. Rauen, William E. Tidyman

Early perturbation of Wnt signaling reveals patterning and invagination-evagination control points in molar tooth development

Development(2021)10.1242/dev.199685

N/A

0DataRank · unranked

21 citations

Tingsheng Yu, Jingjing Li, Jan Prochazka, Amnon Sharir, Jeremy Green +2 more

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.15.435490

N/A

0DataRank · unranked

0 citations

Amnon Sharir, Michael Paul, Hayarpi Torosyan, Christopher Agnew, David R. Raleigh +3 more

Intracellular pH dynamics regulates intestinal stem cell lineage specification

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.28.466337

N/A

0DataRank · unranked

0 citations

Efren Reyes, David Castillo‐Azofeifa, Ophir D. Klein, Diane L. Barber, Todd Nystul +1 more

Microbial signals and lymphotoxin drive TNF-independent death of A20 and ABIN-1 deficient epithelium

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.08.467808

N/A

0DataRank · unranked

0 citations

Elvira Mennillo, Zhongmei Li, Jared L. Bain, Xiaofei Sun, Kimberly Ly +15 more

Programming multicellular assembly with synthetic cell adhesion molecules

Nature(2022)10.1038/s41586-022-05622-z

N/A

0DataRank · unranked

168 citations

Andrew R. Harris, Josiah Gerdts, Ki H. Kim, Coralie Trentesaux, Jonathan T. Ramirez +6 more

A Roadmap for the Human Oral and Craniofacial Cell Atlas

Journal of Dental Research(2022)10.1177/00220345221110768

N/A

0DataRank · unranked

29 citations

Human Cell Atlas Oral and Craniofacial Bionetwork, Inês Sequeira, Kevin M. Byrd, Ana Célia Caetano, Paul T. Sharpe +43 more

A Deep Invertible 3-D Facial Shape Model for Interpretable Genetic Syndrome Diagnosis

IEEE Journal of Biomedical and Health Informatics(2022)10.1109/jbhi.2022.3164848

N/A

0DataRank · unranked

19 citations

Matthias Wilms, J. David Aponte, David C. Katz, Ophir D. Klein, François P. Bernier +4 more

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

Nature Communications(2022)10.1038/s41467-022-30186-x

N/A

0DataRank · unranked

9 citations

Amnon Sharir, Michael Paul, Hayarpi Torosyan, Christopher Agnew, Amy Li +7 more

Ophir D. Klein

Indexed papers

Top data-sharing exemplar

Papers