🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Anang A. Shelat

St. Jude Children's Research Hospital

ORCID: 0000-0002-6266-2910

Also affiliated with Tri-Institutional Therapeutics Discovery Institute

Biochemistry, Genetics and Molecular BiologyMedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile
0.123Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.06.407973
Top 71%
0.123DataRank
Top 71%1 citations

Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin +34 more

Papers

Driven by 20 papers — median percentile 29. Top paper: “MYCN amplification and ATRX mutations are incompatible in neuroblastoma”.

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Nature Communications(2020)10.1038/s41467-020-14682-6
N/A
0.731DataRank · unranked
130 citations

Sara M. Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart +32 more

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

Nature Communications(2021)10.1038/s41467-021-24168-8
N/A
0.624DataRank · unranked
63 citations

Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin +35 more

Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-0896
N/A
0.510DataRank · unranked
29 citations

Justin Williams, Frédérique Zindy, Jingjing Liu, Sarah Robinson, Dana M. Farmer +10 more

Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy

Molecular Cancer(2024)10.1186/s12943-024-02027-6
N/A
0.442DataRank · unranked
18 citations

Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Brandon Bianski +29 more

17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma

iScience(2020)10.1016/j.isci.2020.101996
N/A
0.425DataRank · unranked
16 citations

Ahmed Abu‐Zaid, Wenwei Lin, Jonathan Low, Alireza Abdolvahabi, Hongjian Jin +24 more

Patient-Derived Orthotopic Xenografts and Cell Lines from Pediatric High-Grade Glioma Recapitulate the Heterogeneity of Histopathology, Molecular Signatures, and Drug Response

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.06.407973
Top 71%
0.123DataRank
Top 71%1 citations

Ke Xu, Xiaoyan Zhu, Paige S. Dunphy, Brian Gudenas, Wenwei Lin +34 more

An Evolutionarily Conserved Residue in ABCG2 Regulates the Transport Cycle and Inhibitor Activity

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5185
N/A
0DataRank · unranked
0 citations

Sourav Das, Yao Wang, J.A. Lynch, Yu Fukuda, Medb Wills +4 more

ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma

Neuro-Oncology(2023)10.1093/neuonc/noad064
N/A
0DataRank · unranked
22 citations

Teneema Kuriakose, Brandon Bianski, Nathaniel Twarog, Evan Savage, Ke Xu +19 more

Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small-Molecule Inhibitors

ACS Medicinal Chemistry Letters(2023)10.1021/acsmedchemlett.3c00343
N/A
0DataRank · unranked
5 citations

Molly Sneddon, Joseph E. McPherson, Sourav Das, Clifford T. Gee, Michael J. Grillo +7 more

Fragment-Based NMR Screening of the BPTF PHD Finger Methyl Lysine Reader Leads to the First Small Molecule Inhibitors

ChemRxiv(2023)10.26434/chemrxiv-2023-8t7wn
N/A
0DataRank · unranked
1 citations

Molly Sneddon, Joseph McPherson, Sourav Das, Clifford T. Gee, Michael A. Grillo +7 more

Rationally Designed Potent and Selective CK1α Degraders Exert Antiproliferative Activity Against a Broad Range of Human Cancer Cell Lines

Research Square(2023)10.21203/rs.3.rs-2883533/v1
N/A
0DataRank · unranked
0 citations

Gisele Nishiguchi, Sherif Abdelhamed, Sarah P. Young, Elizabeth A. Caine, Lauren G. Mascibroda +26 more

Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines

Nature Communications(2024)10.1038/s41467-024-44698-1
N/A
0DataRank · unranked
49 citations

Lauren G. Mascibroda, Sarah M. Young, Elizabeth A. Caine, Sherif Abdelhamed, Jeffrey J. Kooijman +30 more

Direct-to-Biology Enabled Molecular Glue Discovery

Journal of the American Chemical Society(2025)10.1021/jacs.5c13496
N/A
0DataRank · unranked
11 citations

Jason Ochoada, Marisa Actis, Kevin McGowan, Jamie Jarusiewicz, Satoshi Yoshimura +17 more

NanoBRET Tracer Development for Class I Bromodomain Target Engagement in Live Cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.25.689777
N/A
0DataRank · unranked
1 citations

Chi-Ming Tsou, Xiang Fu, Anang A. Shelat, William C. K. Pomerantz, Molly Sneddon

Positional isomers of Indolyl-benzodiazepines display dissimilar binding and recruitment of BET transcriptional regulators to targeted genomic loci

Bioorganic Chemistry(2025)10.1016/j.bioorg.2025.108813
N/A
0DataRank · unranked
0 citations

Stanley Nithianantham, Sudip Dey, Rafi Mohammed, Ashraf Mohammed, Kelly Churion +10 more

Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer

Cancer Research(2020)10.1158/0008-5472.can-19-3934
N/A
0DataRank · unranked
41 citations

Liying Chi, Mi‐Kyung Yun, Lyudmila Tsurkan, Nancy E. Martinez, Barbara Jonchère +25 more

Interrogation of SLFN11 in pediatric sarcomas uncovers an unexpected biological role and a novel therapeutic approach to overcoming resistance to replicative stress

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.05.370155
N/A
0DataRank · unranked
1 citations

Marcia Mellado-Largarde, Nancy E. Martinez, Michael R. Clay, Armita Bahrami, Natasha Sahr +17 more

Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

Angewandte Chemie International Edition(2021)10.1002/anie.202108848
N/A
0DataRank · unranked
159 citations

Anand Mayasundari, Fatemeh Keramatnia, Barbara Jonchère, Seung Wook Yang, Jamie Jarusiewicz +22 more

Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

Angewandte Chemie(2021)10.1002/ange.202108848
N/A
0DataRank · unranked
15 citations

Anand Mayasundari, Fatemeh Keramatnia, Barbara Jonchère, Seung Wook Yang, Jamie Jarusiewicz +22 more

Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors

Cell chemical biology(2022)10.1016/j.chembiol.2022.11.006
N/A
0DataRank · unranked
11 citations

Marie-France Langelier, Jessica Gartrell, Ilsa T. Kirby, Daniel J. Sanderson, Daniel S. Bejan +9 more