H. Robert Frost

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.317Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumors

Nature Communications(2024)10.1038/s41467-024-47712-8

Top 53%

0.317DataRank

Top 53%5 citations

Nasim Azizgolshani, Joshua A. Shapiro, Lananh Nguyen, Fred Kolling, George Zanazzi +3 more

Papers

Driven by 46 papers — median percentile 23. Top paper: “Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumors”.

Identifying tumor type and cell type-specific gene expression alterations in pediatric central nervous system tumors

Nature Communications(2024)10.1038/s41467-024-47712-8

Top 53%

0.317DataRank

Top 53%5 citations

Nasim Azizgolshani, Joshua A. Shapiro, Lananh Nguyen, Fred Kolling, George Zanazzi +3 more

Comparison of pathway and gene-level models for cancer prognosis prediction

BMC Bioinformatics(2020)10.1186/s12859-020-3423-z

N/A

0DataRank · unranked

21 citations

Christopher I. Amos, H. Robert Frost, Xingyu Zheng

Zbtb20 Restrains CD8 T Cell Immunometabolism and Restricts Memory Differentiation and Antitumor Immunity

The Journal of Immunology(2020)10.4049/jimmunol.2000459

N/A

0DataRank · unranked

32 citations

Nicholas K. Preiss, Kristine B. Valenteros, Yasmin Kamal, Young-Kwang Usherwood, H. Robert Frost +2 more

Variance-adjusted Mahalanobis (VAM): a fast and accurate method for cell-specific gene set scoring

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.18.954321

N/A

0DataRank · unranked

3 citations

H. Robert Frost

Multi-omic Characterization of the Taxa-function Relationship in Infant Gut Microbiomes

Research Square(2020)10.21203/rs.3.rs-79308/v1

N/A

0DataRank · unranked

0 citations

MARGARET R. KARAGAS, Juliette C. Madan, Erika Dade, Tom J. Palys, Hilary G. Morrison +6 more

Associations between the gut microbiome and metabolome in early life

BMC Microbiology(2021)10.1186/s12866-021-02282-3

N/A

0DataRank · unranked

79 citations

MARGARET R. KARAGAS, Juliette C. Madan, Erika Dade, Thomas J. Palys, Hilary G. Morrison +6 more

Eigenvectors from Eigenvalues Sparse Principal Component Analysis

Journal of Computational and Graphical Statistics(2021)10.1080/10618600.2021.1987254

N/A

0DataRank · unranked

26 citations

H. Robert Frost

Analyzing cancer gene expression data through the lens of normal tissue-specificity

PLoS Computational Biology(2021)10.1371/journal.pcbi.1009085

N/A

0DataRank · unranked

22 citations

H. Robert Frost

Pan-cancer evaluation of gene expression and somatic alteration data for cancer prognosis prediction

BMC Cancer(2021)10.1186/s12885-021-08796-3

N/A

0DataRank · unranked

12 citations

Christopher I. Amos, H. Robert Frost, Xingyu Zheng

Analyzing cancer gene expression data through the lens of normal tissue-specificity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.25.428166

N/A

0DataRank · unranked

5 citations

H. Robert Frost

VAM: Variance-Adjusted Mahalanobis

(2021)10.32614/cran.package.vam

N/A

0DataRank · unranked

0 citations

H. Robert Frost

EESPCA: Eigenvectors from Eigenvalues Sparse Principal Component Analysis (EESPCA)

(2021)10.32614/cran.package.eespca

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Superkine IL-2 and IL-33 Armored CAR T Cells Reshape the Tumor Microenvironment and Reduce Growth of Multiple Solid Tumors

Cancer Immunology Research(2022)10.1158/2326-6066.cir-21-0536

N/A

0DataRank · unranked

59 citations

Shannon L. Ferry, Courtney Schiebout, Cameron Messier, W. James Cook, Leena Abdullah +6 more

Internal oligo(dT) priming introduces systematic bias in bulk and single-cell RNA sequencing count data

NAR Genomics and Bioinformatics(2022)10.1093/nargab/lqac035

N/A

0DataRank · unranked

40 citations

H. Robert Frost, Giovanni Bosco, Marek Svoboda

Intraoperative plasma proteomic changes in cardiac surgery: In search of biomarkers of post‐operative delirium

PROTEOMICS - CLINICAL APPLICATIONS(2022)10.1002/prca.202200066

N/A

0DataRank · unranked

11 citations

Sean P. O’Connor, Heba Naseem, Brooke L. Brauer, Arminja N. Kettenbach, H. Robert Frost +3 more

CBEA: Competitive balances for taxonomic enrichment analysis

PLoS Computational Biology(2022)10.1371/journal.pcbi.1010091

N/A

0DataRank · unranked

5 citations

Anne G. Hoen, H. Robert Frost, Quang P. Nguyen

CAMML with the Integration of Marker Proteins (ChIMP)

Bioinformatics(2022)10.1093/bioinformatics/btac674

N/A

0DataRank · unranked

4 citations

H. Robert Frost, Courtney Schiebout

SPECK: An Unsupervised Learning Approach for Cell Surface Receptor Abundance Estimation for Single Cell RNA-Sequencing Data

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.08.511197

N/A

0DataRank · unranked

4 citations

H. Robert Frost, Azka Javaid

Intraoperative Plasma Proteomic Changes in Cardiac Surgery: In Search of Biomarkers of Post-operative Delirium

medRxiv(2022)10.1101/2022.06.08.22276153

N/A

0DataRank · unranked

2 citations

Sean P. O’Connor, Erika Monteith, Brooke L. Brauer, Arminja N. Kettenbach, H. Robert Frost +3 more

Tissue-adjusted pathway analysis of cancer (TPAC)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.17.484779

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Evaluating trait-based sets for taxonomic enrichment analysis applied to human microbiome data sets

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.16.492155

N/A

0DataRank · unranked

0 citations

Anne G. Hoen, H. Robert Frost, Quang P. Nguyen

A quaternion model for single cell transcriptomics

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.21.501020

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Characterizing control of memory CD8 T cell differentiation by BTB-ZF transcription factor Zbtb20

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.22.504726

N/A

0DataRank · unranked

0 citations

Yasmin Kamal, Owen M. Williams, Chenyang Li, Fred Kolling, Heidi W. Trask +5 more

CAMML with the Integration of Marker Proteins (ChIMP)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.10.491331

N/A

0DataRank · unranked

0 citations

H. Robert Frost, Courtney Schiebout

STREAK: A Supervised Cell Surface Receptor Abundance Estimation Strategy for Single Cell RNA-Sequencing Data using Feature Selection and Thresholded Gene Set Scoring

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.10.516050

N/A

0DataRank · unranked

0 citations

H. Robert Frost, Azka Javaid

Iterative execution of discrete and inverse discrete Fourier transforms with applications for signal denoising via sparsification

arXiv (Cornell University)(2022)10.48550/arxiv.2211.09284

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Cell type-specific interaction analysis using doublets in scRNA-seq

Bioinformatics Advances(2023)10.1093/bioadv/vbad120

N/A

0DataRank · unranked

10 citations

Hannah E Lust, Yina H. Huang, H. Robert Frost, Courtney Schiebout

Characterizing control of memory CD8 T cell differentiation by BTB-ZF transcription factor Zbtb20

Life Science Alliance(2023)10.26508/lsa.202201683

N/A

0DataRank · unranked

6 citations

Yasmin Kamal, Owen M. Wilkins, Chenyang Li, Fred Kolling, Heidi W. Trask +5 more

STREAK: A supervised cell surface receptor abundance estimation strategy for single cell RNA-sequencing data using feature selection and thresholded gene set scoring

PLoS Computational Biology(2023)10.1371/journal.pcbi.1011413

N/A

0DataRank · unranked

5 citations

H. Robert Frost, Azka Javaid

SPECK: an unsupervised learning approach for cell surface receptor abundance estimation for single-cell RNA-sequencing data

Bioinformatics Advances(2023)10.1093/bioadv/vbad073

N/A

0DataRank · unranked

9 citations

H. Robert Frost, Azka Javaid

Reconstruction Set Test (RESET): a computationally efficient method for single sample gene set testing based on randomized reduced rank reconstruction error

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.03.535366

N/A

0DataRank · unranked

4 citations

H. Robert Frost

TPAC: Tissue-Adjusted Pathway Analysis of Cancer (TPAC)

(2023)10.32614/cran.package.tpac

Top 100%

0DataRank

Top 100%0 citations

H. Robert Frost

RESET: Reconstruction Set Test

(2023)10.32614/cran.package.reset

N/A

0DataRank · unranked

0 citations

H. Robert Frost

A generalized eigenvector centrality for multilayer networks with inter-layer constraints on adjacent node importance

Applied Network Science(2024)10.1007/s41109-024-00620-8

N/A

0DataRank · unranked

6 citations

H. Robert Frost

Tissue-adjusted pathway analysis of cancer (TPAC): A novel approach for quantifying tumor-specific gene set dysregulation relative to normal tissue

PLoS Computational Biology(2024)10.1371/journal.pcbi.1011717

N/A

0DataRank · unranked

2 citations

H. Robert Frost

Reconstruction Set Test (RESET): A computationally efficient method for single sample gene set testing based on randomized reduced rank reconstruction error

PLoS Computational Biology(2024)10.1371/journal.pcbi.1012084

N/A

0DataRank · unranked

4 citations

H. Robert Frost

Leveraging cell type-specificity for gene set analysis of single cell transcriptomics

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.25.615040

N/A

0DataRank · unranked

3 citations

H. Robert Frost

Network analysis using Krylov subspace trajectories

arXiv (Cornell University)(2024)10.48550/arxiv.2403.01269

N/A

0DataRank · unranked

0 citations

H. Robert Frost

CAraCAl: CAMML with the integration of chromatin accessibility

BMC Bioinformatics(2024)10.1186/s12859-024-05833-3

N/A

0DataRank · unranked

0 citations

H. Robert Frost, Courtney Schiebout

Randomized Spatial PCA (RASP): a computationally efficient method for dimensionality reduction of high-resolution spatial transcriptomics data

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.20.629785

N/A

0DataRank · unranked

0 citations

Brittany K Goods, H. Robert Frost, Ian K. Gingerich

Revealing tissue architecture through the hypercomplex Fourier analysis of spatial transcriptomics data

Bioinformatics Advances(2024)10.1093/bioadv/vbaf191

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Randomized Spatial PCA (RASP): a computationally efficient method for dimensionality reduction of high-resolution spatial transcriptomics data

Research Square(2025)10.21203/rs.3.rs-6050441/v1

N/A

0DataRank · unranked

1 citations

Brittany A. Goods, H. Robert Frost, Ian K. Gingerich

Network Analysis Using Krylov Subspace Trajectories

Studies in computational intelligence(2025)10.1007/978-3-031-82427-2_26

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Gene Set Optimization for Single Cell Transcriptomics

Lecture notes in computer science(2025)10.1007/978-3-031-89704-7_14

N/A

0DataRank · unranked

0 citations

H. Robert Frost

Variance-adjusted Mahalanobis (VAM): a fast and accurate method for cell-specific gene set scoring

Nucleic Acids Research(2020)10.1093/nar/gkaa582

N/A

0DataRank · unranked

70 citations

H. Robert Frost

Gene set optimization for cancer transcriptomics using sparse principal component analysis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.21.655279

N/A

0DataRank · unranked

0 citations

H. Robert Frost

H. Robert Frost

Indexed papers

Top data-sharing exemplar

Papers