Ruin Moaddel

Also affiliated with Institute on Aging, National Institute on Aging

MedicineBiochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.3Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Variability of 7K and 11K SomaScan Plasma Proteomics Assays

Journal of Proteome Research(2024)10.1021/acs.jproteome.4c00667

Top 24%

0.826DataRank

Top 24%40 citations

Giovanna Fantoni, Francheska Delgado-Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel +3 more

Papers

Driven by 62 papers — median percentile 61. Top paper: “Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration”.

Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration

Translational Psychiatry(2022)10.1038/s41398-022-01941-x

N/A

0.928DataRank · unranked

32 citations

Panos Zanos, Cristan Farmer, Bashkim Kadriu, Patrick J. Morris, Jacqueline Lovett +10 more

Variability of 7K and 11K SomaScan Plasma Proteomics Assays

Journal of Proteome Research(2024)10.1021/acs.jproteome.4c00667

Top 24%

0.826DataRank

Top 24%40 citations

Giovanna Fantoni, Francheska Delgado-Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel +3 more

Plasma proteins related to inflammatory diet predict future cognitive impairment

Molecular Psychiatry(2023)10.1038/s41380-023-01975-7

N/A

0.564DataRank · unranked

42 citations

Lauren Butler, Zhongsheng Peng, Gulzar N. Daya, Abhay Moghekar, Yang An +14 more

A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis

Nature Medicine(2025)10.1038/s41591-025-03890-6

N/A

0.524DataRank · unranked

32 citations

Ruin Moaddel, Justin Kwan, Memoona Rasheed, Paola Ruffo, Natalie Landeck +35 more

Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults

The Journals of Gerontology Series A(2022)10.1093/gerona/glac102

N/A

0.493DataRank · unranked

12 citations

Cissy Zhang, Reyhan Westbrook, Mariann M. Gabrawy, Lolita S. Nidadavolu, Huanle Yang +21 more

Human Metabolome Reference Database in a Biracial Cohort across the Adult Lifespan

Metabolites(2023)10.3390/metabo13050591

Top 39%

0.492DataRank

Top 39%12 citations

Márk Ádám, Enrique Ozcariz, Giovanna Fantoni, Nader Shehadeh, Lisa Turek +5 more

Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure

Nature Communications(2025)10.1038/s41467-025-55911-0

N/A

0.410DataRank · unranked

9 citations

Virginia S. Hahn, Ruin Moaddel, Min Zhu, Sabina Haberlen, Frank J. Palella +15 more

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/wfvq-kk18

N/A

0DataRank · unranked

0 citations

Peixiong Yuan, Yuhong Fang, Cheryl L. Mayo, Xi‐Ping Huang, Todd D. Gould +15 more

Cross-Laboratory Standardization of Preclinical Lipidomics Using Differential Mobility Spectrometry and Multiple Reaction Monitoring

Analytical Chemistry(2021)10.1021/acs.analchem.1c02826

N/A

0DataRank · unranked

100 citations

Yassene Mohammed, Jerzy Adamski, Lisa Bettcher, John A. Bowden, Matías Cabruja +27 more

Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications

Pharmacological Reviews(2021)10.1124/pharmrev.120.000149

N/A

0DataRank · unranked

94 citations

Panos Zanos, Lace M. Riggs, Polymnia Georgiou, Sarah M. Clark, Patrick J. Morris +6 more

Plasma metabolites associated with chronic kidney disease and renal function in adults from the Baltimore Longitudinal Study of Aging

Metabolomics(2021)10.1007/s11306-020-01762-3

N/A

0DataRank · unranked

65 citations

Marta Zampino, Ruin Moaddel, Teresa K. Chen, Qu Tian, Luigi Ferrucci +2 more

A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801

Neurotoxicology and Teratology(2021)10.1016/j.ntt.2021.106993

N/A

0DataRank · unranked

28 citations

Richard Burke, Alok Sharma, Daniel C. Lynch, Leslie E. Lemke-Boutcher, Shiny Mathew +8 more

Proteomics and Epidemiological Models of Human Aging

Frontiers in Physiology(2021)10.3389/fphys.2021.674013

N/A

0DataRank · unranked

23 citations

Ruin Moaddel, Ann Zenobia Moore, Pei‐Lun Kuo, Faraz Faghri, Ravi Tharakan +4 more

Ketamine for Refractory Chronic Migraine: An Observational Pilot Study and Metabolite Analysis

The Journal of Clinical Pharmacology(2021)10.1002/jcph.1920

N/A

0DataRank · unranked

20 citations

Marc C. Torjman, Ruin Moaddel, Jacqueline Lovett, Daniel Katz, William Denk +4 more

Screening of SIRT6 inhibitors and activators: A novel activator has an impact on breast cancer cells

Biomedicine & Pharmacotherapy(2021)10.1016/j.biopha.2021.111452

N/A

0DataRank · unranked

18 citations

Tomáš Kučera, Marjo Huovinen, Jenni Küblbeck, Egīls Bisenieks, Brigita Vı̄gante +7 more

Metabolomic profiles of being physically active and less sedentary: a critical review

Metabolomics(2021)10.1007/s11306-021-01818-y

N/A

0DataRank · unranked

13 citations

Abigail E. Corkum, Ruin Moaddel, Luigi Ferrucci, Qu Tian

The Plasma Proteome Fingerprint Associated with Circulating Carotenoids and Retinol in Older Adults

Journal of Nutrition(2021)10.1093/jn/nxab340

N/A

0DataRank · unranked

12 citations

Marta Zampino, Toshiko Tanaka, Stefania Bandinelli, Ruin Moaddel, Giovanna Fantoni +4 more

The synthesis and characterization of Bri2 BRICHOS coated magnetic particles and their application to protein fishing: Identification of novel binding proteins

Journal of Pharmaceutical and Biomedical Analysis(2021)10.1016/j.jpba.2021.113996

N/A

0DataRank · unranked

2 citations

Nina Kronqvist, Axel Abelein, Lorena Galán-Acosta, Gefei Chen, Michael Landreh +7 more

Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor

Nature Neuroscience(2022)10.1038/s41593-022-01146-x

N/A

0DataRank · unranked

136 citations

Panos Zanos, Ta-Chung M. Mou, Xiaoxian An, Danielle M. Gerhard, Dilyan I. Dryanovski +17 more

Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin

Aging Cell(2022)10.1111/acel.13754

N/A

0DataRank · unranked

70 citations

Maja Mustapić, Ruin Moaddel, Krishna A. Pucha, Jacqueline Lovett, Douglas R. Seals +3 more

Metabolomic Profile of Different Dietary Patterns and Their Association with Frailty Index in Community-Dwelling Older Men and Women

Nutrients(2022)10.3390/nu14112237

N/A

0DataRank · unranked

26 citations

Sameera A. Talegawkar, Yichen Jin, Julián Candia, Qu Tian, Ruin Moaddel +3 more

Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search

Molecular Psychiatry(2022)10.1038/s41380-022-01673-w

N/A

0DataRank · unranked

45 citations

Juan L. Gomez, Meghan L. Carlton, Sherry Lam, Marta Sánchez‐Soto, Patrick J. Morris +9 more

Identification of gingerenone A as a novel senolytic compound

PLoS ONE(2022)10.1371/journal.pone.0266135

N/A

0DataRank · unranked

36 citations

Martina Rossi, Stéphanie Rodriguez, Rachel Munk, Mohammed Khadeer, Kotb Abdelmohsen +3 more

Proteins in the pathway from high red blood cell width distribution to all-cause mortality

EBioMedicine(2022)10.1016/j.ebiom.2022.103816

N/A

0DataRank · unranked

27 citations

Toshiko Tanaka, Richard D. Semba, Giovanna Fantoni, Ruin Moaddel, Julián Candia +4 more

Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (2,6)- and (5R)-Methyl-(2R,6R)-hydroxynorketamines

ACS Chemical Neuroscience(2022)10.1021/acschemneuro.1c00761

N/A

0DataRank · unranked

26 citations

Patrick J. Morris, Kylie M. Konrath, Lace M. Riggs, Natalie R. Hagen, Panos Zanos +6 more

Lipid Peroxidation Induced ApoE Receptor-Ligand Disruption as a Unifying Hypothesis Underlying Sporadic Alzheimer’s Disease in Humans

Journal of Alzheimer s Disease(2022)10.3233/jad-220071

N/A

0DataRank · unranked

22 citations

Gregory S. Keyes, Elizabeth Calzada, Mark S. Horowitz, Daisy Zamora, Jahandar Jahanipour +6 more

Plasma Growth and Differentiation Factor 15 Predict Longitudinal Changes in Bone Parameters in Women, but Not in Men

The Journals of Gerontology Series A(2022)10.1093/gerona/glac079

N/A

0DataRank · unranked

6 citations

Toshiko Tanaka, Richard D. Semba, Giovanna Fantoni, Ruin Moaddel, Julián Candia +4 more

Metabolites Associated with Memory and Gait: A Systematic Review

Metabolites(2022)10.3390/metabo12040356

N/A

0DataRank · unranked

18 citations

Brendan A. Mitchell, Abigail E. Corkum, Ruin Moaddel, Luigi Ferrucci, Qu Tian

Ketamine preservative benzethonium chloride potentiates hippocampal synaptic transmission and binds neurotransmitter receptors and transporters

Neuropharmacology(2022)10.1016/j.neuropharm.2022.109403

N/A

0DataRank · unranked

9 citations

Panos Zanos, Chris F. Powels, Connor J. Fix, Michael Michaelides, Edna F. R. Pereira +3 more

Understanding the Human Aging Proteome Using Epidemiological Models

Methods in molecular biology(2022)10.1007/978-1-0716-1831-8_8

N/A

0DataRank · unranked

1 citations

Ruin Moaddel, Zenobia Moore, Pei‐Lun Kuo, Ravi Tharakan, Toshiko Tanaka +2 more

Experimenter sex modulates mouse biobehavioural and pharmacological responses

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.09.475572

N/A

0DataRank · unranked

2 citations

Panos Zanos, Ta-Chung M. Mou, Xiaoxian An, Danielle M. Gerhard, Dilyan I. Dryanovski +17 more

Plasma metabolomic signatures of dual decline in memory and gait in older adults

GeroScience(2023)10.1007/s11357-023-00792-8

N/A

0DataRank · unranked

25 citations

Michelle Shardell, Pei‐Lun Kuo, Toshiko Tanaka, Eleanor M. Simonsick, Ruin Moaddel +3 more

Sex differences in plasma lipid profiles of accelerated brain aging

Neurobiology of Aging(2023)10.1016/j.neurobiolaging.2023.05.013

N/A

0DataRank · unranked

17 citations

Brendan A. Mitchell, Guray Erus, Christos Davatzikos, Ruin Moaddel, Susan M. Resnick +2 more

Cerebrospinal fluid exploratory proteomics and ketamine metabolite pharmacokinetics in human volunteers after ketamine infusion

iScience(2023)10.1016/j.isci.2023.108527

N/A

0DataRank · unranked

11 citations

Cristan Farmer, Mani Yavi, Bashkim Kadriu, Min Zhu, JINSHUI FAN +13 more

Blood Biomarkers for Healthy Aging

Gerontology(2023)10.1159/000530795

N/A

0DataRank · unranked

10 citations

Toshiko Tanaka, Qu Tian, Zenobia Moore, Ruin Moaddel, Nathan Basisty +3 more

Plant Protein but Not Animal Protein Consumption Is Associated with Frailty through Plasma Metabolites

Nutrients(2023)10.3390/nu15194193

N/A

0DataRank · unranked

9 citations

Jayanta Kumar Das, Yichen Jin, Qu Tian, Ruin Moaddel, Ann Zenobia Moore +4 more

Metabolomic markers mediate erythrocyte anisocytosis in older adults: Results from three independent aging cohorts

Journal of Internal Medicine(2023)10.1111/joim.13612

N/A

0DataRank · unranked

8 citations

Brendan A. Mitchell, Ruin Moaddel, Carmine Zoccali, Stefania Bandinelli, Luigi Ferrucci +1 more

Identification of glycolytic proteins as binding partners of Bri2 BRICHOS domain

Journal of Pharmaceutical and Biomedical Analysis(2023)10.1016/j.jpba.2023.115465

N/A

0DataRank · unranked

3 citations

Makoto Shimozawa, Per Nilsson, Alexey E. Lyashkov, Mohammed Khadeer, Ivar Järving +5 more

Relationships of GDF8 and 11 and Their Antagonists With Decline of Grip Strength Among Older Adults in the Baltimore Longitudinal Study of Aging

The Journals of Gerontology Series A(2023)10.1093/gerona/glad135

N/A

0DataRank · unranked

1 citations

Min Zhu, Ruin Moaddel, Palchamy Elango, Luigi Ferrucci, Richard D. Semba +1 more

Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

Nature Communications(2024)10.1038/s41467-024-45107-3

N/A

0DataRank · unranked

129 citations

Komudi Singh, Samuel R. LaMunion, Mark Hallett, Steve Jacobson, Kong Y. Chen +65 more

A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)‐Hydroxynorketamine in Healthy Volunteers

Clinical Pharmacology & Therapeutics(2024)10.1002/cpt.3391

N/A

0DataRank · unranked

34 citations

Jeffrey T. Guptill, Michelle Mack, Marni Peterson, Stephen J. Byard, Robert J. Twieg +36 more

Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience

Molecular Neurodegeneration(2024)10.1186/s13024-024-00772-2

N/A

0DataRank · unranked

17 citations

Yang An, Abhay Moghekar, Ruin Moaddel, Michael R. Duggan, Zhongsheng Peng +14 more

An exploratory metabolomic comparison of participants with fast or absent functional progression from 2CARE, a randomized, double-blind clinical trial in Huntington’s disease

Scientific Reports(2024)10.1038/s41598-023-50553-y

N/A

0DataRank · unranked

9 citations

Krystal Hunter, John Gaughan, Peggy Auinger, Thomas N. Ferraro, Basant Pradhan +4 more

Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions

Neuropharmacology(2024)10.1016/j.neuropharm.2024.110065

N/A

0DataRank · unranked

3 citations

Jean‐Philippe Guilloux, Céline Defaix, Indira Mendez‐David, Isabelle Etting, Jean‐Claude Alvarez +11 more

Proteomic Signature of HIV-Associated Subclinical Left Atrial Remodeling and Incident Heart Failure

medRxiv(2024)10.1101/2024.02.13.24302797

N/A

0DataRank · unranked

0 citations

Virginia S. Hahn, Ruin Moaddel, Min Zhu, Sabina Haberlen, Frank J. Palella +15 more

Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.03.587904

N/A

0DataRank · unranked

0 citations

Jean‐Philippe Guilloux, Céline Defaix, Indira Mendez‐David, Isabelle Etting, Jean‐Claude Alvarez +11 more

Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers

UNC Libraries(2024)10.17615/fp19-e051

N/A

0DataRank · unranked

0 citations

Ruin Moaddel, Gary Asher, Angela D. M. Kashuba, Mitesh Sanghvi, Ying Xie +3 more

Plasma metabolites in childhood Burkitt lymphoma cases and cancer-free controls in Uganda

Metabolomics(2024)10.1007/s11306-024-02130-1

N/A

0DataRank · unranked

0 citations

Hadijah Nabalende, M. Constanza Camargo, Jacqueline Lovett, Isaac Otim, Ismail D. Legason +13 more

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

Aging Cell(2025)10.1111/acel.70014

N/A

0DataRank · unranked

10 citations

Julián Candia, Ceereena Ubaida‐Mohien, Toshiko Tanaka, Ann Zenobia Moore, Min Zhu +13 more

Qualitative and quantitative lipidomic profiling of cardiolipin, oxidized cardiolipin, and monolysocardiolipin from human skeletal muscle by UPLC-Orbitrap-MSn

Analytica Chimica Acta(2025)10.1016/j.aca.2025.343825

N/A

0DataRank · unranked

2 citations

Josephine M. Egan, Arsun Bektas, Qu Tian, Alexey E. Lyashkov, Luigi Ferrucci +3 more

SomaModules: A Pathway Enrichment Approach Tailored to SomaScan Data

Journal of Proteome Research(2025)10.1021/acs.jproteome.4c01114

N/A

0DataRank · unranked

1 citations

Giovanna Fantoni, Francheska Delgado‐Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel +3 more

A Pilot Proteomic Analysis of Huntington’s Disease by Functional Capacity

Brain Sciences(2025)10.3390/brainsci15010076

N/A

0DataRank · unranked

2 citations

Ruin Moaddel, Andrew McGarry

Senolytic effects of a modified Gingerenone A

npj Aging(2025)10.1038/s41514-025-00230-3

N/A

0DataRank · unranked

1 citations

Chad Sanehira, Gregory S. Keyes, Chang‐Yi Cui, Reza Ahmadkhaniha, Julián Candia +12 more

Choline and CCL22 Are Prognostic Blood Biomarkers for Hermansky-Pudlak Syndrome Pulmonary Fibrosis

American Journal of Respiratory Cell and Molecular Biology(2025)10.1165/rcmb.2024-0628oc

N/A

0DataRank · unranked

1 citations

Abhishek Basu, Ben Long G. Zuo, Mei Xing G Zuo, Kevin O’Brien, Lenny Pommerolle +12 more

Kynurenines link chronic inflammation to functional decline and physical frailty

JCI Insight(2020)10.1172/jci.insight.136091

N/A

0DataRank · unranked

88 citations

Tae Chung, Jacqueline Lovett, Christopher W. Ward, Humberto C. Joca, Huanle Yang +11 more

SomaModules: a pathway enrichment approach tailored to SomaScan data

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.30.667673

Top 100%

0DataRank

Top 100%0 citations

Giovanna Fantoni, Francheska Delgado-Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel +3 more

Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression

Neuropsychopharmacology(2020)10.1038/s41386-020-0663-6

N/A

0DataRank · unranked

83 citations

Jessica R. Gilbert, Ruin Moaddel, Jomy George, Lilian Adeojo, Jacqueline Lovett +7 more

Biological sex and DNA repair deficiency drive Alzheimer’s disease via systemic metabolic remodeling and brain mitochondrial dysfunction

Acta Neuropathologica(2020)10.1007/s00401-020-02152-8

N/A

0DataRank · unranked

76 citations

Vijay R. Varma, Darlene Estrada, Mansi Babbar, Sambuddha Basu, Uma V. Mahajan +6 more

Proteomic signatures of in vivo muscle oxidative capacity in healthy adults

Aging Cell(2020)10.1111/acel.13124

N/A

0DataRank · unranked

21 citations

Ceereena Ubaida‐Mohien, Ruin Moaddel, Michelle Shardell, Alexey E. Lyashkov, Kenneth W. Fishbein +4 more

Cross-sectional analysis of plasma and CSF metabolomic markers in Huntington’s disease for participants of varying functional disability: a pilot study

Scientific Reports(2020)10.1038/s41598-020-77526-9

N/A

0DataRank · unranked

38 citations

John Gaughan, Cory Hackmyer, Jacqueline Lovett, Mohammed Khadeer, Hamza Shaikh +5 more

Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activities

Biomedicine & Pharmacotherapy(2020)10.1016/j.biopha.2020.110701

N/A

0DataRank · unranked

31 citations

Joni Järvenpää, Marjo Huovinen, Anna‐Mari Schroderus, Emmi‐Leena Ihantola, Jenni Küblbeck +4 more

Targeted Deletion of Interleukin-6 in a Mouse Model of Chronic Inflammation Demonstrates Opposing Roles in Aging: Benefit and Harm

The Journals of Gerontology Series A(2020)10.1093/gerona/glaa156

N/A

0DataRank · unranked

24 citations

Lolita S. Nidadavolu, Huanle Yang, Jackie Langdon, Reyhan Westbrook, B.M.W. Tsui +13 more

Ruin Moaddel

Indexed papers

Top data-sharing exemplar

Papers