Asaf Rotem

Also affiliated with AstraZeneca (United States)

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

8.2Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Nature Medicine(2020)10.1038/s41591-020-0844-1

Top 4%

5.6DataRank

Top 4%819 citations

Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro +45 more

Papers

Driven by 44 papers — median percentile 64. Top paper: “Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion”.

Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion

Nature Genetics(2021)10.1038/s41588-021-00779-1

N/A

6.5DataRank · unranked

271 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn Geiger-Schuller, Patricia Ho, Adrienne Luoma +17 more

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

Nature Medicine(2020)10.1038/s41591-020-0844-1

Top 4%

5.6DataRank

Top 4%819 citations

Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro +45 more

Transcriptional mediators of treatment resistance in lethal prostate cancer

Nature Medicine(2021)10.1038/s41591-021-01244-6

N/A

4.8DataRank · unranked

196 citations

Michael S. Cuoco, Jett Crowdis, Alice Bosma-Moody, Zhenwei Zhang, Kevin Bi +35 more

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/761429

N/A

2.5DataRank · unranked

68 citations

Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro, Indresh Singh +44 more

A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Nature Medicine(2024)10.1038/s41591-024-03215-z

Top 15%

1.3DataRank

Top 15%91 citations

Daniel L. Abravanel, Åsa Segerstolpe, Timothy R. Blosser, Yury Goltsev, Yi Cui +57 more

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

Science(2016)10.1126/science.aad0501

N/A

1.3DataRank · unranked

5121 citations

Benjamin Izar, Sanjay M. Prakadan, Marc H. Wadsworth, Daniel Treacy, John J. Trombetta +39 more

Transcriptional mediators of treatment resistance in lethal prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.19.998450

N/A

1.0DataRank · unranked

26 citations

Michael S. Cuoco, Jett Crowdis, Alice Bosma-Moody, Zhenwei Zhang, Kevin Bi +22 more

Spatially organized multicellular immune hubs in human colorectal cancer

Cell(2021)10.1016/j.cell.2021.08.003

N/A

1.0DataRank · unranked

787 citations

Matan Hofree, Siranush Sarkizova, Joshua D. Pirl, Vjola Jorgji, Alborz Bejnood +73 more

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Cancer Cell(2021)10.1016/j.ccell.2021.02.015

N/A

0.964DataRank · unranked

617 citations

Meng Xiao He, Ziad Bakouny, Abhay Kanodia, Sara Napolitano, Jingyi Wu +26 more

A single-cell landscape of high-grade serous ovarian cancer

Nature Medicine(2020)10.1038/s41591-020-0926-0

N/A

0.938DataRank · unranked

518 citations

Itay Tirosh, Elizabeth H. Stover, Isaac Wakiro, Michael S. Cuoco, Idan Alter +30 more

A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.07.574538

Top 22%

0.898DataRank

Top 22%34 citations

Orr Ashenberg, Natalie B. Collins, Åsa Segerstolpe, Sizun Jiang, Michal Slyper +53 more

A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma

Nature Cancer(2025)10.1038/s43018-025-01053-7

N/A

0.351DataRank · unranked

9 citations

Thinh T. Nguyen, Atharva Bhagwat, Akhil Kumar, Bruno Giotti, Benjamin Kepecs +29 more

A cellular and spatial atlas of TP53 -associated tissue remodeling in lung adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.28.546977

Top 50%

0.349DataRank

Top 50%5 citations

Benjamin Kepecs, Navin R. Mahadevan, Jason L. Weirather, Naomi R. Besson, Bruno Giotti +19 more

Multicellular immune hubs and their organization in MMRd and MMRp colorectal cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.30.426796

N/A

0.297DataRank · unranked

4 citations

Matan Hofree, Jonathan Chen, Siranush Sarkizova, Joshua D. Pirl, Vjola Jorgji +71 more

Single-cell RNA-sequencing and -imaging of melanoma ecosystems reveals sources of resistance to immune checkpoint blockade.

Journal of Clinical Oncology(2018)10.1200/jco.2018.36.15_suppl.3074

N/A

0.208DataRank · unranked

1 citations

Livnat Jerby-Arnon, Asaf Rotem, Parin Shah, David Liu, Gao Zhang +13 more

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Cancer Cell(2025)10.1016/j.ccell.2025.05.009

N/A

0.104DataRank · unranked

1 citations

Meng Xiao He, Ziad Bakouny, Abhay Kanodia, Sara Napolitano, Jingyi Wu +25 more

Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Nature Medicine(2025)10.1038/s41591-025-03665-z

N/A

0.104DataRank · unranked

1 citations

Daniel L. Abravanel, Åsa Segerstolpe, Timothy R. Blosser, Yury Goltsev, Yi Cui +57 more

HTAPP_Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using papain, density gradient, and optionally ACK) v1

(2021)10.17504/protocols.io.brvnm65e

N/A

0DataRank · unranked

0 citations

Jingyi Wu, Michal Slyper, Sébastien Vigneau, Asaf Rotem, Orit Rozenblatt–Rosen +4 more

HTAPP_Dissociation of human primary lung cancer resection to a single-cell suspension for single-cell RNA-seq v2

(2020)10.17504/protocols.io.bhbgj2jw

N/A

0DataRank · unranked

0 citations

Avinash Waghray, Julia Waldman, Isaac Wakiro, Mei-Ju Su, Sébastien Vigneau +6 more

HTAPP_Dissociation of human metastatic breast cancer core needle biopsy to a single-cell suspension for single-cell RNA-seq v1

(2019)10.17504/protocols.io.4j7gurn

N/A

0DataRank · unranked

0 citations

Julia Waldman, Jingyi Wu, Abhay Kanodia, Sébastien Vigneau, Asaf Rotem +5 more

HTAPP_Processing human ovarian cancer ascites to a single-cell suspension for single-cell RNA-seq v1

(2019)10.17504/protocols.io.4kbgusn

N/A

0DataRank · unranked

0 citations

Parin Shah, Mei-Ju Su, Isaac Wakiro, Sara Napolitano, Jingyi Wu +7 more

Table S1: Somatic Mutations from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Figshare(2023)10.1158/2326-6066.22542492.v1

N/A

0DataRank · unranked

0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.25.256214

N/A

0DataRank · unranked

10 citations

Peter Winter, Andrew W. Navia, Hannah L. Williams, Alan DenAdel, Radha L. Kalekar +36 more

Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.01.267211

N/A

0DataRank · unranked

5 citations

Johannes C. Melms, Pratiksha I. Thakore, Kathryn R. Geiger-Schuller, Patricia Ho, Adrienne Luoma +15 more

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

Cell(2021)10.1016/j.cell.2021.11.017

N/A

0DataRank · unranked

596 citations

Peter Winter, Andrew W. Navia, Hannah L. Williams, Alan DenAdel, Kristen E. Lowder +42 more

Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.08.515538

N/A

0DataRank · unranked

3 citations

Todd W. Dowrey, Carlos Villacorta Martin, Kevin Bi, Breanna Titchen, Shreya Johri +27 more

Table S1: Somatic Mutations from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

(2023)10.1158/2326-6066.22542492

N/A

0DataRank · unranked

0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors

Science Advances(2023)10.1126/sciadv.add9668

N/A

0DataRank · unranked

34 citations

Todd W. Dowrey, Carlos Villacorta Martin, Kevin Bi, Breanna Titchen, Shreya Johri +30 more

HTAPP_Test protocol_Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using papain and ACK) v1

(2021)10.17504/protocols.io.brvqm65w

N/A

0DataRank · unranked

0 citations

Jingyi Wu, Michal Slyper, Sébastien Vigneau, Asaf Rotem, Orit Rozenblatt–Rosen +4 more

Table S2: CRC risk and DNA repair genes evaluated for germline alterations from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

(2023)10.1158/2326-6066.22542489

Top 100%

0DataRank

Top 100%0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

HTAPP_Dissociation of human metastatic breast cancer lymph node excision biopsy to a single-cell suspension for single-cell RNA-seq (using Collagenase 4 and Dispase II) v1

(2021)10.17504/protocols.io.bua9nsh6

N/A

0DataRank · unranked

0 citations

Jingyi Wu, Sébastien Vigneau, Michal Slyper, Asaf Rotem, Orit Rozenblatt–Rosen +4 more

Supplementary Figures and Legends from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

(2023)10.1158/2326-6066.22542495

N/A

0DataRank · unranked

0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

HTAPP_Enrichment of EpCAM+ cells from single-cell suspension for single-cell RNA-seq v1

(2021)10.17504/protocols.io.bucfnstn

N/A

0DataRank · unranked

0 citations

Sara Napolitano, Sébastien Vigneau, Asaf Rotem, Orit Rozenblatt–Rosen, Prisca Liberali +3 more

HTAPP_Dissociation of primary neuroblastoma core needle biopsy to a single-cell suspension for single-cell RNA-seq (using papain, density gradient, and optionally ACK) v1

(2020)10.17504/protocols.io.bkgnktve

N/A

0DataRank · unranked

0 citations

Jingyi Wu, Michal Slyper, Sébastien Vigneau, Asaf Rotem, Orit Rozenblatt–Rosen +4 more

Supplementary Figures and Legends from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Figshare(2023)10.1158/2326-6066.22542495.v1

N/A

0DataRank · unranked

0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

BRIDGE- HTAPP_Depletion of CD45+ cells from ovarian cancer ascites single cell suspensions for single-cell RNA-Seq v1

(2019)10.17504/protocols.io.4cqgsvw

N/A

0DataRank · unranked

0 citations

Parin Shah, Mei-Ju Su, Isaac Wakiro, Sara Napolitano, Jingyi Wu +7 more

HTAPP_Processing human ovarian cancer ascites to a single-cell suspension for single-cell RNA-seq v2

(2020)10.17504/protocols.io.bhbkj2kw

N/A

0DataRank · unranked

0 citations

Parin Shah, Mei-Ju Su, Isaac Wakiro, Sara Napolitano, Jingyi Wu +7 more

HTAPP_Dissociation of human ovarian cancer resection to a single-cell suspension for single-cell RNA-seq v1

(2019)10.17504/protocols.io.4kaguse

N/A

0DataRank · unranked

0 citations

Sara Napolitano, Jingyi Wu, Sébastien Vigneau, Asaf Rotem, Orit Rozenblatt–Rosen +4 more

HTAPP_Test protocol__Dissociation of primary neuroblastoma resection to a single-cell suspension for single-cell RNA-seq (using collagenase 4) v1

(2021)10.17504/protocols.io.btd7ni9n

N/A

0DataRank · unranked

0 citations

Michal Slyper, Sébastien Vigneau, Asaf Rotem, Orit Rozenblatt–Rosen, Prisca Liberali +3 more

HTAPP_Dissociation of human metastatic breast cancer core needle biopsy to a single-cell suspension for single-cell RNA-seq v2

(2020)10.17504/protocols.io.bhbjj2kn

N/A

0DataRank · unranked

0 citations

Julia Waldman, Jingyi Wu, Abhay Kanodia, Sébastien Vigneau, Asaf Rotem +4 more

Implementation of single-cell genomics as a translational tool in patients with metastatic melanoma.

Journal of Clinical Oncology(2016)10.1200/jco.2016.34.15_suppl.11503

N/A

0DataRank · unranked

0 citations

Itay Tirosh, Asaf Rotem, Parin Shah, Ken Dutton-Regester, Mohammad Fallahi +17 more

Table S2: CRC risk and DNA repair genes evaluated for germline alterations from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

Figshare(2023)10.1158/2326-6066.22542489.v1

Top 100%

0DataRank

Top 100%0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

Data from Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair–Deficient Colorectal Cancer

(2023)10.1158/2326-6066.c.6549951

N/A

0DataRank · unranked

0 citations

David Liu, Matan Hofree, Saud H. AlDubayan, Isaac Wakiro, Mei-Ju Su +17 more

HTAPP_Dissociation of human primary lung cancer resection to a single-cell suspension for single-cell RNA-seq v1

(2019)10.17504/protocols.io.4j8gurw

N/A

0DataRank · unranked

0 citations

Avinash Waghray, Julia Waldman, Isaac Wakiro, Mei-Ju Su, Sébastien Vigneau +6 more

Asaf Rotem

Indexed papers

Top data-sharing exemplar

Papers