Tim A. Benke

Also affiliated with University of Colorado Denver

Biochemistry, Genetics and Molecular BiologyNeuroscienceMedicinePsychology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile

0.104Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Natural history of epilepsy in FOXG1 Syndrome

Epilepsy Research(2025)10.1016/j.eplepsyres.2025.107644

Top 78%

0.104DataRank

Top 78%1 citations

Benjamin Rees, Holly Dubbs, Mollie Lesser, Lucas E. Morgan, Tim A. Benke +4 more

Papers

Driven by 48 papers — median percentile 11. Top paper: “Trofinetide for the treatment of Rett syndrome: a randomized phase 3 study”.

Trofinetide for the treatment of Rett syndrome: a randomized phase 3 study

Nature Medicine(2023)10.1038/s41591-023-02398-1

N/A

4.2DataRank · unranked

190 citations

Alan K. Percy, Tim A. Benke, Elizabeth Berry‐Kravis, Daniel G. Glaze, Eric D. Marsh +5 more

Top caregiver concerns in Rett syndrome and related disorders: data from the US natural history study

Journal of Neurodevelopmental Disorders(2023)10.1186/s11689-023-09502-z

N/A

1.6DataRank · unranked

57 citations

Tim A. Benke, Eric D. Marsh, Bernhard Suter, Lori Silveira, Cary Fu +12 more

Anxiety-like behavior and anxiolytic treatment in the Rett syndrome natural history study

Journal of Neurodevelopmental Disorders(2022)10.1186/s11689-022-09432-2

N/A

0.897DataRank · unranked

45 citations

Jennifer L. Stallworth, Aubin E. Joy, Rebekah E. Dixon, Alexandra E. Scott, Arthur Beisang +16 more

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

eLife(2023)10.7554/elife.88206

N/A

0.535DataRank · unranked

15 citations

Margaux Silvestre, Carrow I. Wells, Jennifer L. Sanderson, Carla A. Ferrer, Han Wee Ong +14 more

Natural history of epilepsy in FOXG1 Syndrome

Epilepsy Research(2025)10.1016/j.eplepsyres.2025.107644

Top 78%

0.104DataRank

Top 78%1 citations

Benjamin Rees, Holly Dubbs, Mollie Lesser, Lucas E. Morgan, Tim A. Benke +4 more

Loss of Grin2a Causes a Transient Delay in the Electrophysiological Maturation of Hippocampal Parvalbumin Interneurons: A Possible Mechanism for Transient Seizure Burden in Patients with Null GRIN2A Variants

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.29.474447

N/A

0DataRank · unranked

3 citations

Anna Vlachos, Chiara Klöckner, Ilona Krey, Tue G. Banke, Nima Shariatzadeh +14 more

CDKL5 deficiency disorder: clinical features, diagnosis, and management

The Lancet Neurology(2022)10.1016/s1474-4422(22)00035-7

N/A

0DataRank · unranked

149 citations

Jenny Downs, Tim A. Benke, Lindsay C. Swanson, Heather E. Olson, Scott Demarest +1 more

Analysis of X‐inactivation status in a Rett syndrome natural history study cohort

Molecular Genetics & Genomic Medicine(2022)10.1002/mgg3.1917

N/A

0DataRank · unranked

23 citations

Kameryn M. Butler, Fatima Abidi, Jennifer Gass, Arthur Beisang, Timothy Feyma +14 more

Negative impact of insomnia and daytime sleepiness on quality of life in individuals with the cyclin‐dependent kinase‐like 5 deficiency disorder

Journal of Sleep Research(2022)10.1111/jsr.13600

N/A

0DataRank · unranked

17 citations

Peter Jacoby, Jacinta Saldaris, Helen Leonard, Tim A. Benke, Eric D. Marsh +2 more

Anthropometric Measures Correspond with Functional Motor Outcomes in Females with Rett Syndrome

The Journal of Pediatrics(2022)10.1016/j.jpeds.2022.01.009

N/A

0DataRank · unranked

16 citations

Suzanne Geerts, Fran Annese, Jeffrey L. Neul, Tim A. Benke, Eric D. Marsh +11 more

Loss of Grin2a causes a transient delay in the electrophysiological maturation of hippocampal parvalbumin interneurons

Communications Biology(2023)10.1038/s42003-023-05298-9

N/A

0DataRank · unranked

38 citations

Anna Vlachos, Chiara Klöckner, Ilona Krey, Tue G. Banke, Nima Shariatzadeh +14 more

A review of the Rett Syndrome Behaviour Questionnaire and its utilization in the assessment of symptoms associated with Rett syndrome

Frontiers in Pediatrics(2023)10.3389/fped.2023.1229553

N/A

0DataRank · unranked

31 citations

Jeffrey L. Neul, Tim A. Benke, Eric D. Marsh, Daniel G. Glaze, Alan K. Percy

Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function

Human Molecular Genetics(2023)10.1093/hmg/ddad104

N/A

0DataRank · unranked

25 citations

Hongjie Yuan, Riley E. Perszyk, Jing Zhang, Sukhan Kim, Kelsey A. Nocilla +7 more

Clinical and functional consequences of GRIA variants in patients with neurological diseases

Cellular and Molecular Life Sciences(2023)10.1007/s00018-023-04991-6

N/A

0DataRank · unranked

19 citations

Riley E. Perszyk, Nana Liu, Yuchen Xu, Subhrajit Bhattacharya, Gil Shaulsky +25 more

Validating the Communication and Symbolic Behavior Scales–Developmental Profile Infant–Toddler Checklist (CSBS–DP ITC) Beyond Infancy in the CDKL5 Deficiency Disorder

Journal of Autism and Developmental Disorders(2023)10.1007/s10803-023-06002-w

N/A

0DataRank · unranked

13 citations

Helen Leonard, Kingsley J. H. Wong, Peter Jacoby, Mary Spence, Eric D. Marsh +4 more

Distribution of hand function by age in individuals with Rett syndrome

Annals of the Child Neurology Society(2023)10.1002/cns3.20038

N/A

0DataRank · unranked

12 citations

Tim A. Benke, Eric D. Marsh, Jane B. Lane, David N. Lieberman, Steven A. Skinner +11 more

Psychometric properties of QI-Disability in CDKL5 Deficiency Disorder: Establishing readiness for clinical trials

Epilepsy & Behavior(2023)10.1016/j.yebeh.2022.109069

N/A

0DataRank · unranked

10 citations

Peter Jacoby, Helen Leonard, Tim A. Benke, Scott Demarest, Eric D. Marsh +2 more

Epileptic spasms in CDKL5 deficiency disorder: Delayed treatment and poor response to first‐line therapies

Epilepsia(2023)10.1111/epi.17630

N/A

0DataRank · unranked

11 citations

Scott Demarest, Elia Pestana‐Knight, Ahsan N. Moosa, Xiaoming Zhang, José R. Pérez‐Pérez +17 more

The development, content and response process validation of a caregiver-reported severity measure for CDKL5 deficiency disorder

Epilepsy Research(2023)10.1016/j.eplepsyres.2023.107231

N/A

0DataRank · unranked

8 citations

Alexandra T. Mackie, Jacinta Saldaris, Helen Leonard, Peter Jacoby, Eric D. Marsh +11 more

Parental age effects and Rett syndrome

American Journal of Medical Genetics Part A(2023)10.1002/ajmg.a.63396

N/A

0DataRank · unranked

3 citations

Lauren M. Baggett, Raymond Caylor, Alan K. Percy, Jeffrey L. Neul, Jane B. Lane +8 more

Top Caregiver Concerns in Rett syndrome and related disorders: data from the US Natural History Study

Research Square(2023)10.21203/rs.3.rs-2566253/v1

N/A

0DataRank · unranked

14 citations

Tim A. Benke, Eric D. Marsh, Bernhard Suter, Lori Silveira, Cary Fu +4 more

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.24.538049

N/A

0DataRank · unranked

0 citations

Margaux Silvestre, Carrow I. Wells, Jennifer L. Sanderson, Carla A. Ferrer, Han Wee Ong +14 more

Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder

Molecular Autism(2024)10.1186/s13229-024-00601-9

N/A

0DataRank · unranked

15 citations

Heather O’Leary, Sarfaraz Nawaz, R Loureiro, Elizabeth C. Davenport, Paul Baxter +14 more

Rett syndrome: The Natural History Study journey

Annals of the Child Neurology Society(2024)10.1002/cns3.20086

N/A

0DataRank · unranked

11 citations

Tim A. Benke, Eric D. Marsh, Jeffrey L. Neul, Alan K. Percy

Communication of individuals with CDKL5 deficiency disorder as observed by caregivers: A descriptive qualitative study

American Journal of Medical Genetics Part A(2024)10.1002/ajmg.a.63570

N/A

0DataRank · unranked

9 citations

Sofia Benson‐Goldberg, Jacinta Saldaris, Judy Lariviere, Helen Leonard, Eric D. Marsh +5 more

International workshop: what is needed to ensure outcome measures for Rett syndrome are fit-for-purpose for clinical trials? June 7, 2023, Nashville, USA

Trials(2024)10.1186/s13063-024-08678-6

N/A

0DataRank · unranked

9 citations

Dominique C. Pichard, Walter E. Kaufmann, Joseph P. Horrigan, Melissa Raspa, Gillian S. Townend +17 more

Clinical Features and Disease Progression in Older Individuals with Rett Syndrome

Genes(2024)10.3390/genes15081107

N/A

0DataRank · unranked

8 citations

Tim A. Benke, Eric D. Marsh, Bernhard Suter, Cary Fu, Robin C. Ryther +9 more

Adapting a measure of gross motor skills for individuals with CDKL5 deficiency disorder: A psychometric study

Epilepsy Research(2024)10.1016/j.eplepsyres.2024.107287

N/A

0DataRank · unranked

7 citations

Peter Jacoby, Eric D. Marsh, Bernhard Suter, Helen Leonard, Heather E. Olson +9 more

Parent‐reported outcome measures evaluating communication in individuals with rare neurodevelopmental disorders: A systematic review

International Journal of Language & Communication Disorders(2024)10.1111/1460-6984.13100

N/A

0DataRank · unranked

5 citations

Jeremiah Ayalde, Samali Kankanange, Jessica Keeley, Helen Leonard, Peter Jacoby +5 more

Psychometric evaluation of clinician‐ and caregiver‐reported clinical severity assessments for individuals with CDKL5 deficiency disorder

Epilepsia(2024)10.1111/epi.18094

N/A

0DataRank · unranked

5 citations

Peter Jacoby, Jenny Downs, Eric D. Marsh, Helen Leonard, Elia Pestana‐Knight +10 more

Modification of a parent-report sleep scale for individuals with CDKL5 deficiency disorder: a psychometric study

Journal of Clinical Sleep Medicine(2024)10.5664/jcsm.11244

N/A

0DataRank · unranked

4 citations

Scott Demarest, Peter Jacoby, Heather E. Olson, Kiran Maski, Elia Pestana‐Knight +9 more

Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia

Journal of Inherited Metabolic Disease(2024)10.1002/jimd.12755

N/A

0DataRank · unranked

3 citations

Hua Jiang, Nicolas Busquet, Jessica Carlsen, Connie Brindley, Tim A. Benke +6 more

Rett syndrome diagnostic odyssey: Limitations of NextGen sequencing

American Journal of Medical Genetics Part A(2024)10.1002/ajmg.a.63725

N/A

0DataRank · unranked

3 citations

Katie Angione, Emily K. Forbes, Mikayla Stoecker, Margarita Sáenz, Jeffrey L. Neul +5 more

Deletions in the CDKL5 5′ untranslated region lead to CDKL5 deficiency disorder

American Journal of Medical Genetics Part A(2024)10.1002/ajmg.a.63843

N/A

0DataRank · unranked

2 citations

Ralph D. Hector, Lindsay C. Swanson, Aubrie Soucy Verran, Emma Sherrill, Zoë Frazier +20 more

Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.26.586818

N/A

0DataRank · unranked

0 citations

Hua Jiang, Nicolas Busquet, Jessica Carlsen, Connie Brindley, Tim A. Benke +6 more

Early life seizures and olfactory communication in rats

Epilepsia(2024)10.1111/epi.18099

N/A

0DataRank · unranked

0 citations

Emily Pope, Jack H. M. Jarvis, Catherine Fiset, Carol Le Maistre‐Matthys, Tim A. Benke +2 more

GRIN2A null variants confer a high risk for early-onset schizophrenia and other mental disorders and potentially enable precision therapy

Molecular Psychiatry(2025)10.1038/s41380-025-03279-4

N/A

0DataRank · unranked

7 citations

Andrea Eoli, Ilona Krey, Bernt Popp, Vincent Strehlow, Dirk Alexander Wittekind +27 more

Parent/caregiver perspectives of meaningful improvement in functional domains for people with CDKL5 deficiency disorder: a mixed-methods study

Quality of Life Research(2025)10.1007/s11136-025-04048-0

N/A

0DataRank · unranked

3 citations

Zoe Skoda, Karen Utley, Eric D. Marsh, Gabrielle Conecker, JayEtta Hecker +9 more

Symptom Onset in Classic Rett Syndrome: Analysis of Initial Clinical Severity Scale Entries

Annals of the Child Neurology Society(2025)10.1002/cns3.70017

N/A

0DataRank · unranked

1 citations

Jeffrey L. Neul, Amitha Ananth, Tim A. Benke, Eric D. Marsh, Alan K. Percy

Content Validation of the Communication Inventory Disability–Observer Reported (CID-OR)

Journal of Child Neurology(2025)10.1177/08830738251369138

N/A

0DataRank · unranked

1 citations

Jacinta Saldaris, Sofia Benson‐Goldberg, Judy Lariviere, Helen Leonard, Eric D. Marsh +5 more

Early life seizures chronically disrupt L-type voltage gated calcium channel regulation of mGluR mediated long term depression via interactions with protein phosphatase 2A

Neurobiology of Disease(2025)10.1016/j.nbd.2025.106884

N/A

0DataRank · unranked

0 citations

Anna Castano, Olivia R. Buonarati, Chad R. Camp, Johannes Hell, Tim A. Benke +1 more

Beyond Seizures as an Outcome Measure: A Global Severity Scoring System for CDKL5 Deficiency Disorder

Brain and Behavior(2025)10.1002/brb3.71061

Top 100%

0DataRank

Top 100%0 citations

Eric D. Marsh, Scott Demarest, Jacinta Saldaris, Helen Leonard, Heather E. Olson +9 more

Automated syndrome diagnosis by three-dimensional facial imaging

Genetics in Medicine(2020)10.1038/s41436-020-0845-y

N/A

0DataRank · unranked

106 citations

J. David Aponte, David C. Katz, Jordan J. Bannister, Sheri L. Riccardi, Nick Mahasuwan +33 more

Trajectory of skill acquisition, loss, and regain in females with classic Rett syndrome

Research Square(2025)10.21203/rs.3.rs-8245192/v1

N/A

0DataRank · unranked

0 citations

Tim A. Benke, Eric D. Marsh, Sarika U. Peters, Cary Fu, Jonathan K. Merritt +2 more

Proof-of-concept for a gene replacement approach to CDKL5 deficiency disorder

Brain(2020)10.1093/brain/awaa055

N/A

0DataRank · unranked

11 citations

Peter C. Kind, Tim A. Benke

Current neurologic treatment and emerging therapies in CDKL5 deficiency disorder

Journal of Neurodevelopmental Disorders(2021)10.1186/s11689-021-09384-z

N/A

0DataRank · unranked

48 citations

Carolyn I. Daniels, Isabel Haviland, Lindsay C. Swanson, Caitlin Greene, Anne Marie M. Denny +14 more

Content Validation of Clinician-Reported Items for a Severity Measure for CDKL5 Deficiency Disorder

Journal of Child Neurology(2021)10.1177/08830738211019576

N/A

0DataRank · unranked

27 citations

Judith Weisenberg, Elia Pestana‐Knight, Eric D. Marsh, Bernhard Suter, Rajsekar R. Rajaraman +10 more

Early-life seizures modify behavioral response to ultrasonic vocalization playback in adult rats

Epilepsy & Behavior(2021)10.1016/j.yebeh.2021.108494

N/A

0DataRank · unranked

12 citations

Catherine Fiset, Jack H. M. Jarvis, Sarah J. MacLeod, Markus Wöhr, Tim A. Benke +2 more

Tim A. Benke

Indexed papers

Top data-sharing exemplar

Papers