Jeffrey R. O’Connell

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.3Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension

Hypertension(2022)10.1161/hypertensionaha.122.19324

Top 24%

0.842DataRank

Top 24%29 citations

Xiao Sun, Karen He, Michael R. Brown, Sarah A. Gagliano Taliun, Jacklyn N. Hellwege +95 more

Papers

Driven by 48 papers — median percentile 66. Top paper: “Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale”.

Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale

Nature Genetics(2020)10.1038/s41588-020-0676-4

N/A

5.3DataRank · unranked

295 citations

Zilin Li, Hufeng Zhou, Sheila M. Gaynor, Yaowu Liu, Han Chen +88 more

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1902766117

N/A

3.0DataRank · unranked

112 citations

Douglas P. Loesch, James A. Perry, Nancy L. Heard‐Costa, Daniel Taliun, Brian E. Cade +93 more

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

Nature(2023)10.1038/s41586-023-05806-1

N/A

2.1DataRank · unranked

107 citations

Jayakrishnan Gopakumar, Bala Bharathi Burugula, Md Mesbah Uddin, Nikolaus Jahn, Julia A. Belk +95 more

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

Nature Communications(2022)10.1038/s41467-022-33510-7

N/A

1.6DataRank · unranked

75 citations

Xihao Li, Zilin Li, Akhil Pampana, David Zhang, Joseph Park +95 more

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies

Nature Genetics(2022)10.1038/s41588-022-01225-6

N/A

1.2DataRank · unranked

63 citations

Corbin Quick, Hufeng Zhou, Sheila M. Gaynor, Yaowu Liu, Han Chen +95 more

Defining the role of common variation in the genomic and biological architecture of adult human height

Nature Genetics(2014)10.1038/ng.3097

N/A

1.1DataRank · unranked

2093 citations

Emilio Rodríguez-Ruiz, The PAGE Consortium, Diana O. Perkins, Tonu Esko, Jian Yang +479 more

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Nature Communications(2021)10.1038/s41467-021-22339-1

N/A

1.1DataRank · unranked

51 citations

Akhil Pampana, Sarah E. Graham, Sanni Ruotsalainen, James A. Perry, Paul S. de Vries +95 more

Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension

Hypertension(2022)10.1161/hypertensionaha.122.19324

Top 24%

0.842DataRank

Top 24%29 citations

Xiao Sun, Karen He, Michael R. Brown, Sarah A. Gagliano Taliun, Jacklyn N. Hellwege +95 more

Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

Nature Communications(2021)10.1038/s41467-021-23655-2

N/A

0.840DataRank · unranked

21 citations

Xiuwen Zheng, Cecelia Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos +91 more

Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative

Human Molecular Genetics(2021)10.1093/hmg/ddab252

Top 28%

0.724DataRank

Top 28%20 citations

Yao Hu, Quan Sun, Deepti Jain, Jai Broome, Ming‐Huei Chen +62 more

A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels

Blood(2024)10.1182/blood.2023021452

N/A

0.601DataRank · unranked

23 citations

Paula Reventún, Michael R. Brown, Adam S. Heath, Jennifer E. Huffman, Ngoc‐Quynh Le +90 more

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program

Communications Biology(2022)10.1038/s42003-022-03702-4

Top 34%

0.582DataRank

Top 34%16 citations

Sheila M. Gaynor, Emily M. Russell, Kenneth E. Westerman, Laura M. Raffield, Timothy D. Majarian +88 more

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.08.007

N/A

0.494DataRank · unranked

26 citations

Caitlin McHugh, Linda M. Polfus, Laura M. Raffield, Meher Preethi Boorgula, Thomas W. Blackwell +88 more

Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

Blood(2024)10.1182/blood.2023022596

N/A

0.416DataRank · unranked

15 citations

Jayna Nicholas, Julie Hahn, Adam S. Heath, Laura M. Raffield, Lisa R. Yanek +95 more

Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

The American Journal of Human Genetics(2023)10.1016/j.ajhg.2023.09.003

N/A

0.416DataRank · unranked

15 citations

Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Jacob A. Holdcraft, Donna K. Arnett +69 more

Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate

Nature Aging(2024)10.1038/s43587-024-00647-7

N/A

0.406DataRank · unranked

14 citations

Michael A. Raddatz, Yash Pershad, Daniel Nachun, Kent D. Taylor, Xiuqing Guo +40 more

The genetic determinants of recurrent somatic mutations in 43,693 blood genomes

Science Advances(2023)10.1126/sciadv.abm4945

N/A

0.396DataRank · unranked

13 citations

Cecelia Laurie, Jai Broome, Kent D. Taylor, Xiuqing Guo, Alan R. Shuldiner +82 more

Clonal hematopoiesis is driven by aberrant activation of TCL1A

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.10.471810

N/A

0.360DataRank · unranked

10 citations

Jayakrishnan Gopakumar, Bala Bharathi Burugula, Md Mesbah Uddin, Nikolaus Jahn, Julia A. Belk +95 more

Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program

medRxiv(2020)10.1101/2020.12.09.20246736

N/A

0.360DataRank · unranked

10 citations

Adrienne M. Stilp, Caitlin McHugh, Shuquan Rao, Deepti Jain, Xiuwen Zheng +74 more

Whole genome sequence analysis of blood lipid levels in >66,000 individuals

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.11.463514

N/A

0.277DataRank · unranked

3 citations

Xihao Li, Zilin Li, Akhil Pampana, David Y Zhang, Joseph Park +80 more

Randomized evaluation of the loss‐of‐function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics

Clinical and Translational Science(2024)10.1111/cts.70079

N/A

0.256DataRank · unranked

4 citations

Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner +5 more

WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE

medRxiv(2023)10.1101/2023.08.21.23293271

N/A

0.165DataRank · unranked

2 citations

Jennifer A. Brody, Mariaelisa Graff, Heather M. Highland, Nathalie Chami, Hanfei Xu +95 more

Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed Whole Genome Sequencing Study

medRxiv(2023)10.1101/2023.06.28.23291966

N/A

0.146DataRank · unranked

1 citations

Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Jacob A. Holdcraft, Donna K. Arnett +69 more

A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations

Molecular Psychiatry(2025)10.1038/s41380-025-02954-w

Top 78%

0.104DataRank

Top 78%1 citations

Thomas W. Winkler, Amy R. Bentley, Clint L. Miller, Aldi T. Kraja, Karen Schwander +95 more

General Kernel Machine Methods for Multi‐Omics Integration and Genome‐Wide Association Testing With Related Individuals

Genetic Epidemiology(2025)10.1002/gepi.22610

N/A

0.104DataRank · unranked

1 citations

Ni Zhao, Anna V. Mikhaylova, Angela Zhang, Wodan Ling, Florian Thibord +25 more

Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles

medRxiv(2023)10.1101/2023.06.07.23291095

N/A

0.104DataRank · unranked

1 citations

Jayna Nicolas, Julie Hahn, Adam S. Heath, Laura M. Raffield, Lisa R. Yanek +95 more

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

UNC Libraries(2025)10.17615/cdn0-cm52

N/A

0DataRank · unranked

0 citations

Russell P. Tracy, Jill M. Johnsen, Hind Bouzid, Nicholas L. Smith, Katherine P. Prothro +95 more

A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction

The Journal of Clinical Endocrinology & Metabolism(2020)10.1210/clinem/dgaa855

N/A

0DataRank · unranked

19 citations

Yue Chen, Mary F. Feitosa, Lawrence F. Bielak, Jeffrey R. O’Connell, Solomon K. Musani +41 more

Population Stratification at the Phenotypic Variance level and Implication for the Analysis of Whole Genome Sequencing Data from Multiple Studies

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.03.973420

N/A

0DataRank · unranked

4 citations

Xiuwen Zheng, Cecelia Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos +10 more

Rare variant enriched identity-by-descent enables the detection of distant relatedness and older divergence between populations

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.05.079541

N/A

0DataRank · unranked

2 citations

TOPMed Population Genetics Working Group, Jeffrey R. O’Connell, Braxton D. Mitchell, Timothy D. O’Connor, Amol C. Shetty

Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges

UNC Libraries(2020)10.17615/4z6y-hr17

N/A

0DataRank · unranked

0 citations

Siiri Bennett, John W. Cole, Qi Sun, Rebecca DeSensi, Rob M. van Dam +33 more

Genetic determinants of the ankle-brachial index: A meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium

UNC Libraries(2020)10.17615/cknt-8a26

N/A

0DataRank · unranked

0 citations

Jane F. Ferguson, Susan Redline, Christina L. Wassel, L. Adrienne Cupples, George Papanicolaou +27 more

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

UNC Libraries(2020)10.17615/y892-y714

N/A

0DataRank · unranked

0 citations

Wen‐Chi Hsueh, Eric Orwoll, Serkalem Demissie, Liisa Byberg, Arjun Verma +95 more

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation

UNC Libraries(2020)10.17615/frhz-yk87

N/A

0DataRank · unranked

0 citations

Juan M. Peralta, Olivia Weeks, Gudnason, Vilmunder, Kurt Lohman, Andrew D. Johnson +63 more

Allele-specific variation atAPOEincreases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer’s disease and myocardial infarction

Human Molecular Genetics(2021)10.1093/hmg/ddab096

N/A

0DataRank · unranked

41 citations

Bratati Kahali, Annapurna Kuppa, Yanhua Chen, Xiaomeng Du, Mary F. Feitosa +31 more

Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program

PLoS ONE(2021)10.1371/journal.pone.0253611

N/A

0DataRank · unranked

8 citations

Han Chen, Mary L. Biggs, Sylvia Wassertheil‐Smoller, Jan Bressler, Marguerite R. Irvin +24 more

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

Nature Methods(2022)10.1038/s41592-022-01640-x

N/A

0DataRank · unranked

109 citations

Xihao Li, Hufeng Zhou, Sheila M. Gaynor, Margaret Sunitha Selvaraj, Theodore Arapoglou +95 more

Genome-wide association meta-analysis identifies 17 loci associated with nonalcoholic fatty liver disease

Nature Genetics(2023)10.1038/s41588-023-01497-6

N/A

0DataRank · unranked

204 citations

Xiaomeng Du, Annapurna Kuppa, Mary F. Feitosa, Lawrence F. Bielak, Jeffrey R. O’Connell +32 more

Interactions between genes involved in physiological dysregulation and axon guidance: role in Alzheimer’s disease

Frontiers in Genetics(2023)10.3389/fgene.2023.1236509

N/A

0DataRank · unranked

2 citations

Svetlana Ukraintseva, Olivia Bagley, Hongzhe Duan, Deqing Wu, Igor Akushevich +9 more

Metabolite signatures of chronological age, aging, survival, and longevity

Cell Reports(2024)10.1016/j.celrep.2024.114913

N/A

0DataRank · unranked

42 citations

Stefano Monti, Michael S. Lustgarten, Zeyuan Song, Dylan Ellis, Qu Tian +27 more

A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations

medRxiv(2024)10.1101/2024.03.07.24303870

N/A

0DataRank · unranked

1 citations

Thomas W. Winkler, Amy R. Bentley, Clint L. Miller, Aldi T. Kraja, Karen Schwander +95 more

Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits

UNC Libraries(2024)10.17615/egdp-v066

N/A

0DataRank · unranked

0 citations

Jennifer G. Robinson, M.A. Richard, K. Schwander, Xueling Sim, Michael R. Brown +95 more

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

UNC Libraries(2024)10.17615/f2gw-he44

N/A

0DataRank · unranked

0 citations

Lisa Warsinger Martin, Chen-Huan Yu, Pamela J. Schreiner, Tuomo Rankinen, Sina A. Gharib +95 more

A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations

Research Square(2024)10.21203/rs.3.rs-4163414/v1

Top 100%

0DataRank

Top 100%0 citations

Pavithra Nagarajan, Thomas W. Winkler, Amy R. Bentley, Clint L. Miller, Aldi T. Kraja +95 more

Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding

Journal of Thrombosis and Haemostasis(2025)10.1016/j.jtha.2025.04.029

N/A

0DataRank · unranked

4 citations

Adam S. Heath, Jennifer E. Huffman, James Baker, Natalie R. Hasbani, Sarah A. Gagliano Taliun +39 more

Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals

Genome biology(2025)10.1186/s13059-025-03698-0

N/A

0DataRank · unranked

2 citations

Xihao Li, Zilin Li, Eric Van Buren, Sara Haidermota, Darina Postupaka +95 more

Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids

Translational Psychiatry(2025)10.1038/s41398-025-03418-z

N/A

0DataRank · unranked

0 citations

Michael R. Brown, Solomon K. Musani, Karen Schwander, Thomas W. Winkler, Mario Sims +93 more

Exonic Variation and Its Clinical Impact in 7221 Old Order Amish

American Journal of Medical Genetics Part A(2025)10.1002/ajmg.a.64212

N/A

0DataRank · unranked

0 citations

Ebuka Onyenobi, Joshua P. Lewis, Brady Gaynor, James A. Perry, Kristin A. Maloney +17 more

Jeffrey R. O’Connell

Indexed papers

Top data-sharing exemplar

Papers