Gordon J. Freeman

Also affiliated with Dana-Farber Cancer Institute

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.1Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

Nucleic Acids Research(2021)10.1093/nar/gkab804

Top 7%

3.1DataRank

Top 7%135 citations

Cheryl J. Wong, Lin Yang, Nofal Ouardaoui, Dian Li, Wubing Zhang +15 more

Papers

Driven by 60 papers — median percentile 93. Top paper: “TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response”.

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

Nucleic Acids Research(2021)10.1093/nar/gkab804

Top 7%

3.1DataRank

Top 7%135 citations

Cheryl J. Wong, Lin Yang, Nofal Ouardaoui, Dian Li, Wubing Zhang +15 more

Spatial signatures identify immune escape via PD-1 as a defining feature of T-cell/histiocyte-rich large B-cell lymphoma

Blood(2020)10.1182/blood.2020006464

N/A

1.9DataRank · unranked

59 citations

Jason L. Weirather, Margaretha G.M. Roemer, Mikel Lipschitz, Alyssa Kelley, Pei-Hsuan Chen +26 more

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease

Nature(2025)10.1038/s41586-025-08852-z

N/A

0.998DataRank · unranked

64 citations

Ayshwarya Subramanian, Zhuoran Yin, Ahad Khalilnezhad, Yufan Wu, Danyang He +38 more

Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

Cell(2021)10.1016/j.cell.2021.01.022

N/A

0.897DataRank · unranked

394 citations

Orr Ashenberg, Itay Tirosh, Simon Gritsch, Elizabeth M. Perez, Sascha Marx +38 more

PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

Nature(2022)10.1038/s41586-022-05257-0

N/A

0.868DataRank · unranked

326 citations

Koichi Araki, Maria A. Cardenas, Peng Li, Rohit R. Jadhav, Haydn Kissick +26 more

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-2291

N/A

0.776DataRank · unranked

176 citations

Prafulla C. Gokhale, Maria C. Speranza, Benjamin K. Eschle, Michael J. Poitras, Margaret K. Wilkens +18 more

The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

Cell Reports(2020)10.1016/j.celrep.2020.107827

N/A

0.734DataRank · unranked

132 citations

Jernej Godec, Pamela M. Odorizzi, Keturah Brown, Kathleen B. Yates, Shin Foong Ngiow +11 more

Evaluation of predictive biomarkers for nivolumab in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) from the CheckMate-025 (CM-025) trial.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.5023

N/A

0.599DataRank · unranked

12 citations

Opeyemi A. Jegede, Miriam Sant’Angelo, Sonia Moreno, David A. Braun, Megan Wind‐Rotolo +15 more

PD-1 is requisite for skin TRM cell formation and specification by TGFβ

Nature Immunology(2025)10.1038/s41590-025-02228-1

N/A

0.583DataRank · unranked

21 citations

Eric Wang, Abhinav Jaiswal, Piotr Konieczny, Tae‐Gyun Kim, Christopher J. Nirschl +25 more

Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma

Clinical & Translational Immunology(2023)10.1002/cti2.1453

N/A

0.533DataRank · unranked

10 citations

Takashi Shimizu, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Genki Usui +18 more

Clonal tracing reveals diverse patterns of response to immune checkpoint blockade

Genome biology(2020)10.1186/s13059-020-02166-1

N/A

0.524DataRank · unranked

32 citations

Xiaoqing Wang, Xihao Hu, Peng Jiang, Ziyi Li, Nicole Traugh +21 more

The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy

Frontiers in Immunology(2023)10.3389/fimmu.2023.1237715

N/A

0.500DataRank · unranked

27 citations

Xia Bu, Yunfei Wang, Michael R. Gomez, James A. Torchia, Ping Hua +7 more

Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity

Cancer Immunology Research(2024)10.1158/2326-6066.cir-24-0463

N/A

0.477DataRank · unranked

23 citations

SeongJun Han, Amy Y. Huang, Thao H. Nguyen, Jefte M. Drijvers, Hannah Creasey +15 more

Stratified analysis identifies HIF-2 α as a therapeutic target for highly immune-infiltrated melanomas

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.29.620300

N/A

0.231DataRank · unranked

3 citations

Kelly P. Burke, Ryan Porter, Lynn Meiger, Peter Fatouros, Jiekun Yang +24 more

Immunogenomic characterization of advanced clear cell renal cell carcinoma treated with PD-1 blockade.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.5010

N/A

0.165DataRank · unranked

2 citations

Yue Hou, Ziad Bakouny, Miriam Ficial, Miriam Sant’Angelo, Petra Ross‐Macdonald +15 more

PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8 + T cells in lymphoid tissue

Science Immunology(2021)10.1126/sciimmunol.abh3034

N/A

0DataRank · unranked

41 citations

Bhrugu Yagnik, Alexander P. R. Bally, Kristen N. Morrow, Shelly Wang, Thomas H. Vanderford +4 more

700 Increasing MHC-I expression to potentiate immune checkpoint blockade therapy

Regular and Young Investigator Award Abstracts(2021)10.1136/jitc-2021-sitc2021.700

N/A

0DataRank · unranked

1 citations

Wubing Zhang, Xiaoqing Wang, Peng Jiang, Nicole Traugh, Ziyi Li +28 more

Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.23.461484

N/A

0DataRank · unranked

0 citations

Antigoni Morou, Mathieu Dubé, Julia Niessl, Amy E. Baxter, Olivier Tastet +8 more

Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells

Cell Metabolism(2022)10.1016/j.cmet.2022.06.008

N/A

0DataRank · unranked

348 citations

Jared H. Rowe, Sheila Johnson, Shakchhi Joshi, Giulia Notarangelo, Kiran Kurmi +5 more

USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy

Nature Communications(2022)10.1038/s41467-022-29401-6

N/A

0DataRank · unranked

152 citations

Xueliang Gao, Tiantian Zhang, Baishan Jiang, Mingming Hu, Xia Bu +18 more

mTOR regulates T cell exhaustion and PD-1–targeted immunotherapy response during chronic viral infection

Journal of Clinical Investigation(2022)10.1172/jci160025

N/A

0DataRank · unranked

89 citations

Charles M. Perkins, Yamato Sajiki, Chase Chastain, Rajesh M. Valanparambil, Andreas Wieland +7 more

PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2202148119

N/A

0DataRank · unranked

26 citations

Kehmia Titanji, Hasan Ahmed, Ravi Dyavar Shetty, Lakshmi Chennareddi, Gordon J. Freeman +3 more

Enterohepatic Shunt-Driven Cholemia Predisposes to Liver Cancer

Gastroenterology(2022)10.1053/j.gastro.2022.08.033

N/A

0DataRank · unranked

21 citations

Piu Saha, Rachel M. Golonka, Jun Zou, Jessica L. Petrick, Ahmed A. Abokor +18 more

An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy

mAbs(2022)10.1080/19420862.2022.2088454

N/A

0DataRank · unranked

19 citations

Allison Sheen, Luciano Santollani, Emi A. Lutz, Brianna M. Lax, Joseph R. Palmeri +3 more

Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function

EBioMedicine(2022)10.1016/j.ebiom.2022.104254

N/A

0DataRank · unranked

18 citations

Antigoni Morou, Mathieu Dubé, Julia Niessl, Amy E. Baxter, Olivier Tastet +8 more

Preclinical models for development of immune–oncology therapies

Immuno Oncology Insights(2022)10.18609/ioi.2022.41

N/A

0DataRank · unranked

13 citations

Sarah E. Shelton, Gabriella Kastrunes, David A. Barbie, Gordon J. Freeman, Wayne A. Marasco +1 more

Immunoregulatory effects of RGMb in gut inflammation

Frontiers in Immunology(2022)10.3389/fimmu.2022.960329

N/A

0DataRank · unranked

9 citations

Bettina P. Iliopoulou, Katie Hsu, Hsin‐Hsu Wu, Tom Erkers, Kavya Swaminathan +8 more

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.28.497997

N/A

0DataRank · unranked

0 citations

Sampurna Chatterjee, Elizabeth M. Perez, Simon Gritsch, Sylvie Roberge, Mark Duquette +19 more

Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance

Nature(2023)10.1038/s41586-023-06026-3

N/A

0DataRank · unranked

187 citations

Francesca S. Gazzaniga, Meng–Huang Wu, Amalia K. Luthens, Jacob E. Gillis, Wenfeng Zheng +11 more

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

Nature(2023)10.1038/s41586-023-05940-w

N/A

0DataRank · unranked

137 citations

Qiwei Wang, Qi Wang, Michelle L. Ramseier, Sanjay M. Prakadan, Weihua Wang +17 more

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Nature Communications(2023)10.1038/s41467-023-36881-7

N/A

0DataRank · unranked

118 citations

Heng Du, Damir Khabibullin, Mahsa Zarei, Kevin Wei, Gordon J. Freeman +3 more

STING agonism overcomes STAT3-mediated immunosuppression and adaptive resistance to PARP inhibition in ovarian cancer

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2022-005627

N/A

0DataRank · unranked

93 citations

Qiwei Wang, Antons Martincuks, Michael J. Kearns, Tao Jiang, Ziying Lin +13 more

PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors

Science Immunology(2023)10.1126/sciimmunol.adg0539

N/A

0DataRank · unranked

81 citations

Peter H. Wang, Judong Lee, William Henry Hudson, Satomi Ando, Koichi Araki +10 more

Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1301

N/A

0DataRank · unranked

52 citations

Ilaria Elia, Osmaan Shahid, Emily F. Gaudiano, Natalia E. Sifnugel, Sheila Johnson +11 more

PD-1 Expression on Intratumoral Regulatory T Cells Is Associated with Lack of Benefit from Anti–PD-1 Therapy in Metastatic Clear-Cell Renal Cell Carcinoma Patients

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-2274

N/A

0DataRank · unranked

37 citations

Opeyemi A. Jegede, Sayed Matar, Nourhan El Ahmar, Destiny J. West, Emily Walton +16 more

Regulation of HHLA2 expression in kidney cancer and myeloid cells

BMC Cancer(2023)10.1186/s12885-023-11496-9

N/A

0DataRank · unranked

7 citations

Nahuel Perrot, Zimo Huang, Rupal S. Bhatt, Aseman Sheshdeh Bagheri, Nourhan El Ahmar +6 more

Novel Antimurine Thyroid-Stimulating Hormone Receptor Monoclonal Antibodies

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy(2023)10.1089/mab.2022.0037

N/A

0DataRank · unranked

1 citations

James A. Torchia, Gordon J. Freeman, Alyssa N. Klee

Data from Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

(2023)10.1158/1078-0432.c.6530000

N/A

0DataRank · unranked

0 citations

Koichiro Haruki, Mai Chan Lau, Andressa Dias Costa, Juha P. Väyrynen, Tomotaka Ugai +36 more

Data from Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

(2023)10.1158/1078-0432.c.6530000.v1

N/A

0DataRank · unranked

0 citations

Koichiro Haruki, Mai Chan Lau, Andressa Dias Costa, Juha P. Väyrynen, Tomotaka Ugai +36 more

Data from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1

(2023)10.1158/2326-6066.c.6550380

N/A

0DataRank · unranked

0 citations

Abdulla Berjis, Julie C. Konge, Kathleen M. Mahoney, Alyssa N. Klee, Samuel S. Freeman +14 more

Data from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1

(2023)10.1158/2326-6066.c.6550380.v1

N/A

0DataRank · unranked

0 citations

Abdulla Berjis, Julie C. Konge, Kathleen M. Mahoney, Alyssa N. Klee, Samuel S. Freeman +14 more

The B7:CD28 family and friends: Unraveling coinhibitory interactions

Immunity(2024)10.1016/j.immuni.2024.01.013

N/A

0DataRank · unranked

120 citations

Apoorvi Chaudhri, Gordon J. Freeman, Arlene H. Sharpe, Kelly P. Burke

Improving IL12 immunotherapy in glioblastoma by targeting the long noncoding RNA INCR1

Journal of Neuro-Oncology(2025)10.1007/s11060-025-04978-2

N/A

0DataRank · unranked

6 citations

Josephina A.M.A. Gadet, Gordon J. Freeman, E. Antonio Chiocca, Marco Mineo, Shikha Saini

RGMb drives macrophage infiltration to aggravate kidney disease

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2418739122

N/A

0DataRank · unranked

6 citations

Ming Yue, Chunhua Xu, Jing Zhang, Huiling Hong, Jiahuan Lu +13 more

PD-1 regulates tumor-infiltrating CD8+ T cells in both a cell-intrinsic and a cell-extrinsic fashion

The Journal of Experimental Medicine(2025)10.1084/jem.20230542

N/A

0DataRank · unranked

6 citations

Samuel C. Markson, Thomas S. Conway, Vikram R. Juneja, Osmaan Shahid, Kelly P. Burke +13 more

Exposed phosphatidylserine is a non-classical inhibitory molecule during CD8 T cell exhaustion 2323

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.250

N/A

0DataRank · unranked

0 citations

Ewelina Sobierajska, Minghao Gong, Daniel T. McManus, Maheshwor Thapa, Judong Lee +12 more

Interaction of SHP-2 SH2 domains with PD-1 ITSM induces PD-1 dimerization and SHP-2 activation

Communications Biology(2020)10.1038/s42003-020-0845-0

N/A

0DataRank · unranked

169 citations

Jonathan S. Duke‐Cohan, Apoorvi Chaudhri, Halil‐Ibrahim Aksoylar, Qi Wang, Anders H. Berg +3 more

Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas

Annals of Oncology(2020)10.1016/j.annonc.2020.04.011

N/A

0DataRank · unranked

153 citations

Leonie K. de Klerk, Xiaoshu Xu, Tania Fleitas, Kevin X. Liu, YuhJong Liu +15 more

PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance

The Journal of Experimental Medicine(2020)10.1084/jem.20182232

N/A

0DataRank · unranked

262 citations

Juhi R. Kuchroo, Peter T. Sage, Dan Liang, Loise M. Francisco, Jessica N. Buck +13 more

KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1

Cancer Immunology Research(2020)10.1158/2326-6066.cir-20-0315

N/A

0DataRank · unranked

113 citations

Abdulla Berjis, Julie C. Konge, Kathleen M. Mahoney, Alyssa N. Klee, Samuel S. Freeman +14 more

Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade

Cancer Discovery(2020)10.1158/2159-8290.cd-19-1416

N/A

0DataRank · unranked

71 citations

David Liu, Diana Miao, Bart Lutterbach, Alexander L. DeVine, Chenyu Lin +19 more

Retinoblastoma protein expression and its predictors in triple-negative breast cancer

npj Breast Cancer(2020)10.1038/s41523-020-0160-4

N/A

0DataRank · unranked

47 citations

Andrew J. Goss, Judy E. Garber, Vanda F. Torous, Edward T. Richardson, Miriam J. Haviland +9 more

Soluble PD-L1 as a marker of progressive disease on nivolumab in kidney cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.6_suppl.746

N/A

0DataRank · unranked

1 citations

Petra Ross‐Macdonald, Sachet A. Shukla, David A. Braun, Linan Song, Eliseo Veras +7 more

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

UNC Libraries(2020)10.17615/2vfb-gr51

N/A

0DataRank · unranked

0 citations

Gordon J. Freeman, Victor Tkachev, Catarina Sacristán, Ian A. Blair, Govindarajan Thangavelu +30 more

Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors

UNC Libraries(2020)10.17615/j6a6-ag16

N/A

0DataRank · unranked

0 citations

Jacob B. Reibel, Jeremy H. Tchaicha, Julián Carretero, Pasi A. Jänne, Mohit Butaney +22 more

Emerging concepts in PD-1 checkpoint biology

Seminars in Immunology(2021)10.1016/j.smim.2021.101480

N/A

0DataRank · unranked

186 citations

James A. Torchia, Apoorvi Chaudhri, Arlene H. Sharpe, Gordon J. Freeman, Kristen E. Pauken

Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0812

N/A

0DataRank · unranked

283 citations

Wubing Zhang, Xiaoqing Wang, Peng Jiang, Nicole Traugh, Ziyi Li +28 more

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

Science Immunology(2021)10.1126/sciimmunol.abf3861

N/A

0DataRank · unranked

147 citations

Shunsuke Sakai, Nickiana E. Lora, Sivaranjani Namasivayam, Paul J. Baker, Olena Kamenyeva +16 more

Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses

Science Translational Medicine(2021)10.1126/scitranslmed.abd8636

N/A

0DataRank · unranked

97 citations

Masayoshi Kawakubo, Vikram R. Juneja, Mack Y. Su, Tal Hadad Erlich, Martin W. LaFleur +32 more

Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-4009

N/A

0DataRank · unranked

96 citations

Koichiro Haruki, Mai Chan Lau, Andressa Dias Costa, Juha P. Väyrynen, Tomotaka Ugai +36 more

Gordon J. Freeman

Indexed papers

Top data-sharing exemplar

Papers