Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade

Cancer Discovery(2020)10.1158/2159-8290.cd-19-1416Source: DataRank Database

Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade is a research paper published in Cancer Discovery (2020). On theSindex it has a DataRank of 2.7. It has been cited 71 times, with 68 citing works in its 1-hop citation network.

N/A

2.7DataRank · unranked

Scored on demand from live citation data

Open Access71 citations · 68 citing works in its network

Download PDF

Cite:

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 3.51)OA: bronzeTopics (79)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 24%Citation Network 76%

Base Score Contribution

0.641

From this paper's citation signal

Citation Network Contribution

2.1

From 59 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 68 citers.

A Low Tumor Mutational Burden and PTEN Mutations Are Predictors of a Negative Response to PD-1 Blockade in MSI-H/dMMR Gastrointestinal Tumors
Clinical Cancer Research2021113 citations38 referencesContributes 0.125
Melanoma Genomics: Shifting Focus from Inter- to Intrapatient Variation
Cancer Discovery20232 citations10 referencesContributes 0.110
FAM83D promotes the proliferation and migration of hepatocellular carcinoma cells by inhibiting the FBXW7/MCL1 pathway
Translational Cancer Research202211 citations27 referencesContributes 0.092
Cancer-associated fibroblast exosomes promote prostate cancer metastasis through miR-500a-3p/FBXW7/HSF1 axis under hypoxic microenvironment
Cancer Gene Therapy202417 citations33 referencesContributes 0.088
Identification and validation of a ferroptosis‐related gene signature for predicting survival in skin cutaneous melanoma
Cancer Medicine202266 citations52 referencesContributes 0.081

Authors (24)

David Liu ORCID,Diana Miao ORCID,Bart Lutterbach,Alexander L. DeVine ORCID,Chenyu Lin ORCID

Live enrichment

PubMed:32371478 OpenAlex:https://openalex.org/W3023967107

Stand Up To Cancer

Grant: #SU2C-AACR-IRG 16-17

NIH

Grant: R01CA227388

NCI

Grant: P50CA101942

National Institutes of Health

Grant: 5R01CA227388-03

Integrative Somatic and Germline Computational Biology to Redefine Clinical Actionability in Solid Tumors

National Institutes of Health

Grant: 2P50CA101942-11A1

DF/HCC Kidney Cancer SPORE

FWCI

3.51

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronze

journalhttps://cancerdiscovery.aacrjournals.org/content/candisc/10/9/1296.full.pdf

publisherhttps://cancerdiscovery.aacrjournals.org/content/candisc/10/9/1296.full.pdf

publisherhttps://aacrjournals.org/cancerdiscovery/article-pdf/10/9/1296/1818912/1296.pdf

journalhttps://doi.org/10.1158/2159-8290.cd-19-1416

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32371478

Fields of Study

RNA Interference and Gene DeliveryExtracellular vesicles in diseaseinterferon and immune responses0301 basic medicine03 medical and health sciencesAgedAnimalsAntibodies, Monoclonal, HumanizedCell Line, TumorDEAD Box Protein 58Disease Models, AnimalDrug Resistance, NeoplasmF-Box-WD Repeat-Containing Protein 7Gene Expression Regulation, NeoplasticHeLa CellsHumansImmune Checkpoint InhibitorsInterferon-Induced Helicase, IFIH1Loss of Function MutationMaleMiceMutagenesis, Site-DirectedProgrammed Cell Death 1 ReceptorRNA, Double-StrandedReceptors, ImmunologicSkin NeoplasmsTumor Microenvironment

MeSH Terms

DEAD Box Protein 58Interferon-Induced Helicase, IFIH1Loss of Function MutationF-Box-WD Repeat-Containing Protein 7Immune Checkpoint InhibitorsAgedAnimalsDisease Models, AnimalHeLa CellsHumansMaleReceptors, ImmunologicRNA, Double-StrandedSkin NeoplasmsGene Expression Regulation, NeoplasticMutagenesis, Site-DirectedDrug Resistance, NeoplasmCell Line, TumorMiceTumor MicroenvironmentProgrammed Cell Death 1 ReceptorAntibodies, Monoclonal, Humanized

Keywords

BlockadeRNA silencingVirologyBiologyChemistryRNA interferenceRNAGeneticsGeneReceptorMaleF-Box-WD Repeat-Containing Protein 7Interferon-Induced Helicase, IFIH1Programmed Cell Death 1 ReceptorAntibodies, Monoclonal, HumanizedGene Expression Regulation, NeoplasticDisease Models, AnimalMiceDrug Resistance, NeoplasmLoss of Function MutationCell Line, TumorMutagenesis, Site-DirectedAnimalsDEAD Box Protein 58HumansReceptors, ImmunologicImmune Checkpoint InhibitorsAgedHeLa CellsRNA, Double-Stranded

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being