🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Brian Spencer

University of Southern California

ORCID: 0000-0002-7486-1941

Also affiliated with University of California San Diego

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
12.6Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Initial sequencing and comparative analysis of the mouse genome

Nature(2002)10.1038/nature01262
Top 1%
12.6DataRank
Top 1%7282 citations

Robert H. Waterston, Kerstin Lindblad‐Toh, Julien Lagarde, Josep F. Abril, PANKAJ AGARWAL +189 more

Papers

Driven by 11 papers — median percentile 99. Top paper: “Initial sequencing and comparative analysis of the mouse genome”.

Initial sequencing and comparative analysis of the mouse genome

Nature(2002)10.1038/nature01262
Top 1%
12.6DataRank
Top 1%7282 citations

Robert H. Waterston, Kerstin Lindblad‐Toh, Julien Lagarde, Josep F. Abril, PANKAJ AGARWAL +189 more

Parkinson’s Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein

Neuron(2023)10.1016/j.neuron.2022.12.020
N/A
0.292DataRank · unranked
6 citations

Simona Eleuteri, Lingbo Li, Nicholas J. Kramer, Justin W. Chartron, Brian Spencer +10 more

RETRACTED ARTICLE: Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells

Experimental & Molecular Medicine(2021)10.1038/s12276-021-00562-6
N/A
0DataRank · unranked
41 citations

Somin Kwon, Michiyo Iba, Brian Spencer, Edward Rockenstein, Michael Mante +7 more

Novel systemic delivery of a peptide-conjugated antisense oligonucleotide to reduce α-synuclein in a mouse model of Alzheimer's disease

Neurobiology of Disease(2023)10.1016/j.nbd.2023.106285
N/A
0DataRank · unranked
13 citations

Rijwan Uddin Ahammad, Brian Spencer, Chengbiao Wu, Eliezer Masliah, Robert A. Rissman +1 more

Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy

Neurobiology of Disease(2023)10.1016/j.nbd.2023.106010
N/A
0DataRank · unranked
15 citations

André Leitão, Savannah Fang, Yingli Gu, Sophia Barber, Rhiannon Gilliard-Telefoni +11 more

Hippocampal Reduction of α-Synuclein via RNA Interference Improves Neuropathology in Alzheimer’s Disease Mice

Journal of Alzheimer s Disease(2023)10.3233/jad-230232
N/A
0DataRank · unranked
2 citations

Brian Spencer, Floyd Sarsoza, Jennifer Ngolab, Jessica Amalraj, Eliezer Masliah +3 more

Differential roles of human tau isoforms in the modulation of inflammation and development of neuropathology

Neurobiology of Disease(2025)10.1016/j.nbd.2025.106942
N/A
0DataRank · unranked
3 citations

Aaron Schueler, Daniel Sung, Robert A. Rissman, Brian Spencer

A splice‐switching antisense oligonucleotide targeting APP reduces accumulation of α‐synuclein in a mouse model of Parkinson's disease

Alzheimer s & Dementia Translational Research & Clinical Interventions(2025)10.1002/trc2.70117
N/A
0DataRank · unranked
2 citations

Brian Spencer, Bao Quach, Sahar Salehi, Robert A. Rissman, Rijwan Uddin Ahammad

Neutral pH-Selective Inhibition of Cytosolic Cathepsin B: A Novel Drug Targeting Strategy for Traumatic Brain Injury and Alzheimer’s Disease

ACS Chemical Biology(2025)10.1021/acschembio.5c00463
N/A
0DataRank · unranked
3 citations

Sonia Podvin, Michael C. Yoon, Von V. Phan, Jazmin Florio, Brian Spencer +8 more

Systemic delivery of anti-sense oligonucleotide targeting a-synuclein for the treatment of multiple system atrophy

Research Square(2025)10.21203/rs.3.rs-7908950/v1
N/A
0DataRank · unranked
0 citations

Bao Quach, Sahar Salehi, Robert A. Rissman, Brian Spencer

Preclinical validation of a potent γ-secretase modulator for Alzheimer’s disease prevention

The Journal of Experimental Medicine(2021)10.1084/jem.20202560
N/A
0DataRank · unranked
74 citations

Moorthi Ponnusamy, Olga Prikhodko, Yuhuan Xie, Can Zhang, Phuong Nguyen +19 more