Steven Henikoff

Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

Also affiliated with Howard Hughes Medical Institute, Fred Hutch Cancer Center

Biochemistry, Genetics and Molecular BiologyAgricultural and Biological Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Comparative validation of the D. melanogaster modENCODE transcriptome annotation

Genome Research(2014)10.1101/gr.159384.113

Top 5%

4.6DataRank

Top 5%192 citations

David Sturgill, Jiaxin Qu, Huaiyang Jiang, Soo Park, Nathan Boley +67 more

Papers

Driven by 61 papers — median percentile 93. Top paper: “Comparative validation of the D. melanogaster modENCODE transcriptome annotation”.

Comparative validation of the D. melanogaster modENCODE transcriptome annotation

Genome Research(2014)10.1101/gr.159384.113

Top 5%

4.6DataRank

Top 5%192 citations

David Sturgill, Jiaxin Qu, Huaiyang Jiang, Soo Park, Nathan Boley +67 more

Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

eLife(2020)10.7554/elife.63274

N/A

3.6DataRank · unranked

166 citations

Jorja G. Henikoff, Hatice S Kaya-Okur, Kami Ahmad, Steven Henikoff

Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

Science(2010)10.1126/science.1198374

Top 9%

2.4DataRank

Top 9%1089 citations

Sushmita Roy, Jason Ernst, Peter V. Kharchenko, Yanxiao Zhang, Richard S. Sandstrom +172 more

Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones

eLife(2020)10.7554/elife.61090

N/A

1.9DataRank · unranked

72 citations

Michael P. Meers, Derek H. Janssens, Jorja G. Henikoff, Heather Feldman, Patrick J. Paddison +6 more

The BAF chromatin remodeler synergizes with RNA polymerase II and transcription factors to evict nucleosomes

Nature Genetics(2023)10.1038/s41588-023-01603-8

N/A

1.7DataRank · unranked

92 citations

Steven Henikoff, Sandipan Brahma

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

Nature Protocols(2009)10.1038/nprot.2009.86

N/A

1.3DataRank · unranked

6705 citations

Steven Henikoff, Pauline C. Ng, P. Naresh Kumar, Prateek Kumar

Unlocking the secrets of the genome

Nature(2009)10.1038/459927a

N/A

1.0DataRank · unranked

822 citations

Susan E. Celniker, Laura A. L. Dillon, Mark B. Gerstein, Kristin C. Gunsalus, Steven Henikoff +11 more

A Comprehensive Map of Insulator Elements for the Drosophila Genome

PLoS Genetics(2010)10.1371/journal.pgen.1000814

N/A

0.877DataRank · unranked

344 citations

Christopher D. Brown, Parantu K. Shah, Yanxiao Zhang, Carolyn A. Morrison, Philipp Kapranov +11 more

RNA polymerase II at histone genes predicts outcome in human cancer

Science(2025)10.1126/science.ads2169

N/A

0.735DataRank · unranked

42 citations

Ye Zheng, Ronald M. Paranal, Yiling Xu, Jacob E. Greene, Jorja G. Henikoff +7 more

Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

eLife(2022)10.7554/elife.74338

N/A

0.615DataRank · unranked

12 citations

Feinan Wu, Derek H. Janssens, Jherek Swanger, Ahmed Diab, Heather M Feldman +6 more

Expansion of human centromeric arrays in cells undergoing break-induced replication

Cell Reports(2024)10.1016/j.celrep.2024.113851

N/A

0.449DataRank · unranked

19 citations

Paul B. Talbert, Joanna S. Yi, Richard O. Adeyemi, Steven Henikoff, Soyeon Showman

MLL oncoprotein levels influence leukemia lineage identities

Nature Communications(2024)10.1038/s41467-024-53399-8

N/A

0.418DataRank · unranked

9 citations

M. Durán, Dominik J. Otto, Weifang Wu, Joanna S. Yi, Danielle Kirkey +6 more

Unlocking the secrets of the genome

UNC Libraries(2020)10.17615/aw2c-np04

N/A

0.154DataRank · unranked

1 citations

Laura A. L. Dillon, Grigorios Georgolopoulos, Kristin C. Gunsalus, Steven Henikoff, Gary H. Karpen +10 more

Simplified Epigenome Profiling Using Antibody-tethered Tagmentation

BIO-PROTOCOL(2021)10.21769/bioprotoc.4043

N/A

0DataRank · unranked

29 citations

Jorja G. Henikoff, Kami Ahmad, Steven Henikoff

The H3.3K27M oncohistone antagonizes reprogramming in Drosophila

PLoS Genetics(2021)10.1371/journal.pgen.1009225

N/A

0DataRank · unranked

20 citations

Steven Henikoff, Kami Ahmad

ChEC-seq produces robust and specific maps of transcriptional regulators

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.11.430831

N/A

0DataRank · unranked

10 citations

Robert A. Policastro, Steven Henikoff, Gabriel E. Zentner

High throughput genome-wide single cell protein:DNA binding site mapping by targeted insertion of promoters (TIP-seq)

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.17.435909

N/A

0DataRank · unranked

7 citations

Vishnu Dileep, Steven Henikoff, David M. Gilbert, Daniel A. Bartlett

Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.19.464955

N/A

0DataRank · unranked

1 citations

Feinan Wu, Derek H. Janssens, Jherek Swanger, Heather Feldman, Robert A. Amezquita +5 more

Simultaneous CUT&Tag profiling of the accessible and silenced regulome in single cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.19.473377

N/A

0DataRank · unranked

1 citations

Dominik J. Otto, Michael P. Meers, Manu Setty, Kami Ahmad, Steven Henikoff +1 more

Multifactorial profiling of epigenetic landscapes at single-cell resolution using MulTI-Tag

Nature Biotechnology(2022)10.1038/s41587-022-01522-9

N/A

0DataRank · unranked

100 citations

Geneva Llagas, Derek H. Janssens, Christine A. Codomo, Steven Henikoff, Michael P. Meers

Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0692

N/A

0DataRank · unranked

70 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman +28 more

CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells

Genome biology(2022)10.1186/s13059-022-02642-w

N/A

0DataRank · unranked

64 citations

Dominik J. Otto, Michael P. Meers, Manu Setty, Kami Ahmad, Steven Henikoff +1 more

CUT&RUN Profiling of the Budding Yeast Epigenome

Methods in molecular biology(2022)10.1007/978-1-0716-2257-5_9

N/A

0DataRank · unranked

20 citations

Steven Henikoff, Sandipan Brahma

Managing the Steady State Chromatin Landscape by Nucleosome Dynamics

Annual Review of Biochemistry(2022)10.1146/annurev-biochem-032620-104508

N/A

0DataRank · unranked

29 citations

Steven Henikoff, Srinivas Ramachandran, Kami Ahmad

In situ tools for chromatin structural epigenomics

Protein Science(2022)10.1002/pro.4458

N/A

0DataRank · unranked

13 citations

Kami Ahmad, Steven Henikoff

Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.21.496879

N/A

0DataRank · unranked

8 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Adam J. Kreitzman, Jay F. Sarthy +28 more

Epigenetic pioneering by SWI/SNF family remodelers

Molecular Cell(2023)10.1016/j.molcel.2023.10.045

N/A

0DataRank · unranked

68 citations

Sandipan Brahma, Steven Henikoff, Kami Ahmad

Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression

Cancer Cell(2023)10.1016/j.ccell.2023.03.021

N/A

0DataRank · unranked

59 citations

Sandipan Brahma, Sonali Arora, Cynthia L. Wladyka, Patrick Hoang, Steven Blinka +20 more

Scalable single-cell profiling of chromatin modifications with sciCUT&Tag

Nature Protocols(2023)10.1038/s41596-023-00905-9

N/A

0DataRank · unranked

27 citations

Jacob E. Greene, Steven J. Wu, Christine A. Codomo, Samuel S. Minot, Scott N. Furlan +3 more

Chromosome-specific maturation of the epigenome in the Drosophila male germline

eLife(2023)10.7554/elife.89373

N/A

0DataRank · unranked

18 citations

Steven Henikoff, Kami Ahmad, James T. Anderson

Active enhancers strengthen insulation by RNA-mediated CTCF binding at chromatin domain boundaries

Genome Research(2023)10.1101/gr.276643.122

N/A

0DataRank · unranked

43 citations

Bharath Saravanan, Kaivalya Walavalkar, Umer Farooq, Anurag Kumar Singh, Radhakrishnan Sabarinathan +5 more

CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.04.539469

N/A

0DataRank · unranked

6 citations

Ana R. Tronco, Giancarlo Bonora, Truong N. Nguyen, Jitendra Thakur, Joel B. Berletch +7 more

KMT2A oncoproteins induce epigenetic resistance to targeted therapies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.29.573681

N/A

0DataRank · unranked

6 citations

Melodie Duran, Dominik J. Otto, Weifang Wu, Joanna S. Yi, Danielle Kirkey +6 more

Chromosome-specific maturation of the epigenome in the Drosophila male germline

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.24.529909

N/A

0DataRank · unranked

3 citations

Steven Henikoff, Kami Ahmad, James M. Anderson

Chromosome-specific maturation of the epigenome in the Drosophila male germline

(2023)10.7554/elife.89373.2

N/A

0DataRank · unranked

2 citations

Steven Henikoff, Kami Ahmad, James Anderson

Data from Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

(2023)10.1158/2159-8290.c.6549837.v1

N/A

0DataRank · unranked

0 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman +28 more

Data from Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

(2023)10.1158/2159-8290.c.6549837.v2

N/A

0DataRank · unranked

0 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman +28 more

β-catenin repositions over time

Cell Systems(2023)10.1016/j.cels.2023.06.008

N/A

0DataRank · unranked

0 citations

Steven Henikoff, Sarah M. Leichter

Reviewer #1 (Public Review): Chromosome-specific maturation of the epigenome in the Drosophila male germline

(2023)10.7554/elife.89373.2.sa1

N/A

0DataRank · unranked

0 citations

Steven Henikoff, Kami Ahmad, James Anderson

Author Response: Chromosome-specific maturation of the epigenome in the Drosophila male germline

(2023)10.7554/elife.89373.2.sa3

N/A

0DataRank · unranked

0 citations

Steven Henikoff, Kami Ahmad, James Anderson

Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

Immunity(2024)10.1016/j.immuni.2024.01.011

N/A

0DataRank · unranked

42 citations

Yun Lo, Elena Fulton, Olivia G. Waltner, Tamer B. Shabaneh, Sylvain Simon +24 more

Chromatin as an old and new anticancer target

Trends in cancer(2024)10.1016/j.trecan.2024.05.005

N/A

0DataRank · unranked

20 citations

Katerina V. Gurova, Jay F. Sarthy, Gábor Szabó, Steven Henikoff, Jacques Neefjes

Chromatin-bound U2AF2 splicing factor ensures exon inclusion

Molecular Cell(2025)10.1016/j.molcel.2025.04.013

N/A

0DataRank · unranked

9 citations

Kami Ahmad, Steven Henikoff, Weifang Wu

Total whole-arm chromosome losses predict malignancy in human cancer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2505385122

N/A

0DataRank · unranked

8 citations

Kami Ahmad, Steven Henikoff, Ye Zheng

CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation

BMC Biology(2025)10.1186/s12915-025-02137-7

N/A

0DataRank · unranked

4 citations

Ana R. Tronco, Giancarlo Bonora, Truong N. Nguyen, Jitendra Thakur, Joel B. Berletch +8 more

Editorial: Current insights in Epigenetics and Epigenomics

Frontiers in Epigenetics and Epigenomics(2025)10.3389/freae.2025.1566501

N/A

0DataRank · unranked

3 citations

Sharon Dent, Raúl Mostoslavsky, Ting Wang, Luca Comai, Steven Henikoff

Multi-omics analysis reveals CLEC2A is a leukemia-restricted CART target in KMT2A-rearranged Acute Myeloid Leukemia

Research Square(2025)10.21203/rs.3.rs-7768680/v1

N/A

0DataRank · unranked

0 citations

Derek H. Janssens, Margaret G. Hines, Seungmin Shin, Grace Hawkins, Melia Blankenfeld +26 more

Polycomb misregulation in enterocytes drives tissue decline in the aging Drosophila intestine

Genome Research(2025)10.1101/gr.281058.125

N/A

0DataRank · unranked

0 citations

Kami Ahmad, Steven Henikoff, Sarah M. Leichter

A needed nomenclature for nucleosomes

Molecular Cell(2025)10.1016/j.molcel.2025.08.029

N/A

0DataRank · unranked

12 citations

Geneviève Almouzni, Andrew J. Andrews, Karim-Jean Armache, C.H. Arrowsmith, Sung Hee Baek +33 more

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

Nature Communications(2020)10.1038/s41467-020-14682-6

N/A

0DataRank · unranked

129 citations

Sara M. Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart +32 more

Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome

Nature Communications(2020)10.1038/s41467-020-19879-3

N/A

0DataRank · unranked

64 citations

Giancarlo Bonora, Jordan P. Lewandowski, Jitendra Thakur, Galina N. Filippova, Steven Henikoff +7 more

Biparental contributions of the H2A.B histone variant control embryonic development in mice

PLoS Biology(2020)10.1371/journal.pbio.3001001

N/A

0DataRank · unranked

22 citations

Anna Wood, Derek H. Janssens, Selina Kindelay, Michael T. Eickbush, Steven J. Wu +5 more

Evolution: Heterochromatin Diversity in Early-Branching Land Plants

Current Biology(2020)10.1016/j.cub.2019.12.044

N/A

0DataRank · unranked

7 citations

Kami Ahmad, Steven Henikoff

Single-cell analysis of chromatin silencing programs in development and tumor progression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.04.282418

N/A

0DataRank · unranked

12 citations

Scott N. Furlan, Anca B. Mihalas, Hatice S Kaya-Okur, Abdullah H. Feroze, Samuel Emerson +10 more

Efficient chromatin accessibility mapping in situ by nucleosome-tethered tagmentation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.15.043083

N/A

0DataRank · unranked

2 citations

Jorja G. Henikoff, Hatice S Kaya-Okur, Kami Ahmad, Steven Henikoff

The H3.3K27M oncohistone antagonizes reprogramming in Drosophila

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.10.375881

N/A

0DataRank · unranked

1 citations

Steven Henikoff, Kami Ahmad

Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression

Nature Biotechnology(2021)10.1038/s41587-021-00865-z

N/A

0DataRank · unranked

213 citations

Scott N. Furlan, Anca B. Mihalas, Hatice S Kaya-Okur, Abdullah H. Feroze, Samuel Emerson +10 more

Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia

Nature Genetics(2021)10.1038/s41588-021-00941-9

N/A

0DataRank · unranked

99 citations

Michael P. Meers, Steven J. Wu, Ekaterina Babaeva, Soheil Meshinchi, Jay F. Sarthy +3 more

The structure of a virus-encoded nucleosome

Nature Structural & Molecular Biology(2021)10.1038/s41594-021-00585-7

N/A

0DataRank · unranked

75 citations

Stephen Abini-Agbomson, Miao Wang, Rachel Lee, Nikita Vasilyev, Jenny Zhang +8 more

High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)

The Journal of Cell Biology(2021)10.1083/jcb.202103078

N/A

0DataRank · unranked

50 citations

Vishnu Dileep, Tetsuya Handa, Yasuyuki Ohkawa, Hiroshi Kimura, Steven Henikoff +2 more

Short H2A histone variants are expressed in cancer

Nature Communications(2021)10.1038/s41467-020-20707-x

N/A

0DataRank · unranked

47 citations

Marie Bleakley, Robert K. Bradley, Harmit S. Malik, Steven Henikoff, Antoine Molaro +2 more

Steven Henikoff

Indexed papers

Top data-sharing exemplar

Papers