Robert H. Mach

Also affiliated with University of Pennsylvania

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection”.

A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection

Science(2024)10.1126/science.adn4955

N/A

1.7DataRank · unranked

75 citations

Alexa Semon, Nile U. Bayard, Yi‐Gen Pan, Garima Dwivedi, James J. Knox +24 more

Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim

Journal of Clinical Investigation(2022)10.1172/jci156679

N/A

1.1DataRank · unranked

32 citations

Daniel A. Jacome, Joshua K. Cho, Vincent Tu, Anthony J. Young, Tiffany Dominguez +15 more

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.16.422851

N/A

0.406DataRank · unranked

14 citations

Yeqiao Zhou, Zhendong Cao, Peter Deraska, Moniher Deb, Eri Arai +10 more

Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease

eNeuro(2020)10.1523/eneuro.0317-20.2020

N/A

0DataRank · unranked

32 citations

Martí Colom‐Cadena, Aladdin Riad, Jinbin Xu, Meharvan Singh, Carmen Abate +6 more

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells

Nature Cell Biology(2021)10.1038/s41556-020-00624-3

N/A

0DataRank · unranked

151 citations

Yeqiao Zhou, Zhendong Cao, Peter Deraska, Moniher Deb, Eri Arai +10 more

PARkinson's: From cellular mechanisms to potential therapeutics

Pharmacology & Therapeutics(2021)10.1016/j.pharmthera.2021.107968

N/A

0DataRank · unranked

17 citations

Laura N. Puentes, Robert H. Mach, Zsofia Lengyel‐Zhand

Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods

Biomolecules(2021)10.3390/biom11040529

N/A

0DataRank · unranked

9 citations

Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu, Robert R. Luedtke +2 more

Imaging Sensitive and Drug-Resistant Bacterial Infection with [ 11 C]-TMP: In Vitro and First-in-Human Evaluation

medRxiv(2021)10.1101/2021.09.21.21262899

N/A

0DataRank · unranked

2 citations

Daniel A. Jacome, Joshua K. Cho, Vincent Tu, Anthony J. Young, Tiffany Dominguez +15 more

Harnessing the Intrinsic Photochemistry of Isoxazoles for the Development of Chemoproteomic Crosslinking Methods

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.23.473999

N/A

0DataRank · unranked

0 citations

Vinayak Vishnu Pagar, Hee Jong Kim, Samantha X. Pancoe, Robert H. Mach, Benjamin A. García +2 more

[18F]FluorThanatrace ([18F]FTT) PET Imaging of PARP-Inhibitor Drug-Target Engagement as a Biomarker of Response in Ovarian Cancer, a Pilot Study

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-1602

N/A

0DataRank · unranked

32 citations

Sarah B. Gitto, Mehran Makvandi, Hyoung Kim, Sergey Medvedv, Joanna K. Weeks +16 more

Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma

Communications Biology(2022)10.1038/s42003-022-04209-8

N/A

0DataRank · unranked

24 citations

Minu Samanta, Paul Martorano, Hwan Lee, Sarah B. Gitto, Khushbu Patel +18 more

Harnessing the intrinsic photochemistry of isoxazoles for the development of chemoproteomic crosslinking methods

Chemical Communications(2022)10.1039/d2cc02263j

N/A

0DataRank · unranked

14 citations

Vinayak Vishnu Pagar, Hee Jong Kim, Samantha X. Pancoe, Wai‐Kit Chia, Robert H. Mach +3 more

Screening of σ2 Receptor Ligands and In Vivo Evaluation of 11C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use as a σ2 Receptor Brain PET Tracer

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00191

N/A

0DataRank · unranked

16 citations

Ji Youn Lee, Chia‐Ju Hsieh, Aladdin Riad, Nicholas J. Izzo, Susan M. Catalano +3 more

[18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

EJNMMI Research(2022)10.1186/s13550-022-00914-x

N/A

0DataRank · unranked

14 citations

Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli, Evan Gallagher +6 more

Design and Synthesis of Conformationally Flexible Scaffold as Bitopic Ligands for Potent D3-Selective Antagonists

International Journal of Molecular Sciences(2022)10.3390/ijms24010432

N/A

0DataRank · unranked

6 citations

Ji Youn Lee, Chia‐Ju Hsieh, Michelle Taylor, Robert R. Luedtke, Robert H. Mach +1 more

Identification and Characterization of ML321: A Novel and Highly Selective D 2 Dopamine Receptor Antagonist with Efficacy in Animal Models That Predict Atypical Antipsychotic Activity

ACS Pharmacology & Translational Science(2022)10.1021/acsptsci.2c00202

N/A

0DataRank · unranked

5 citations

Ashley N. Nilson, Noelia Boldizsar, Trevor Doyle, Ramona M. Rodriguiz, Vladimir M. Pogorelov +14 more

Using 18 F-NOS PET Imaging to Measure Pulmonary Inflammation in Electronic and Combustible Cigarette Users: A Pilot Study

medRxiv(2022)10.1101/2022.06.15.22276438

N/A

0DataRank · unranked

1 citations

Robert K. Doot, Anthony J. Young, Hsiaoju Lee, Erin K. Schubert, Corinde E. Wiers +5 more

[ 18 F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.05.487092

N/A

0DataRank · unranked

0 citations

Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli, Evan Gallagher +6 more

Identification and Characterization of ML321: a Novel and Highly Selective D 2 Dopamine Receptor Antagonist with Efficacy in Animal Models that Predict Atypical Antipsychotic Activity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.14.516475

N/A

0DataRank · unranked

0 citations

Ashley N. Nilson, Noelia Boldizsar, Trevor Doyle, Ramona M. Rodriguiz, Vladimir M. Pogorelov +14 more

A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00779

N/A

0DataRank · unranked

38 citations

Wai Kit Chia, Chia‐Ju Hsieh, Dinahlee Saturnino Guarino, Thomas J. A. Graham, Zsofia Lengyel‐Zhand +16 more

Molecular Imaging of Pulmonary Inflammation in Users of Electronic and Combustible Cigarettes: A Pilot Study

Journal of Nuclear Medicine(2023)10.2967/jnumed.122.264529

N/A

0DataRank · unranked

22 citations

Robert K. Doot, Anthony J. Young, Hsiaoju Lee, Erin K. Schubert, Corinde E. Wiers +5 more

Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search

Molecular Imaging and Biology(2023)10.1007/s11307-023-01814-9

N/A

0DataRank · unranked

17 citations

Guilong Tian, Zsofia Lengyel‐Zhand, Chia‐Ju Hsieh, Marshall G. Lougee, Aladdin Riad +13 more

FRETing about the details: Case studies in the use of a genetically encoded fluorescent amino acid for distance‐dependent energy transfer

Protein Science(2023)10.1002/pro.4633

N/A

0DataRank · unranked

12 citations

Chloe M. Jones, Kyle D. Shaffer, Yarra Venkatesh, Sam Giannakoulias, Ryann M. Perez +9 more

Effects of ranolazine on right ventricular function, fluid dynamics, and metabolism in patients with precapillary pulmonary hypertension: insights from a longitudinal, randomized, double-blinded, placebo controlled, multicenter study

Frontiers in Cardiovascular Medicine(2023)10.3389/fcvm.2023.1118796

N/A

0DataRank · unranked

12 citations

Paul R. Forfia, Anjali Vaidya, Gautam Ramani, Robert A. deKemp, Robert H. Mach +7 more

Synthesis of bitopic ligands based on fallypride and evaluation of their affinity and selectivity towards dopamine D2 and D3 receptors

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115751

N/A

0DataRank · unranked

3 citations

Chia‐Ju Hsieh, Michelle Taylor, Ji Youn Lee, Aladdin Riad, Robert R. Luedtke +2 more

Synthesis and Pharmacological Characterization of a Difluorinated Analogue of Reduced Haloperidol as a Sigma-1 Receptor Ligand

ACS Chemical Neuroscience(2023)10.1021/acschemneuro.2c00791

N/A

0DataRank · unranked

2 citations

Michelle Taylor, Tamara R. McInnis, Zhenglan Chen, Sadakatali S. Gori, Heather M. LaPorte +9 more

Design and Synthesis of D3R Bitopic Ligands with Flexible Secondary Binding Fragments: Radioligand Binding and Computational Chemistry Studies

Molecules(2023)10.3390/molecules29010123

N/A

0DataRank · unranked

1 citations

Chia‐Ju Hsieh, Michelle Taylor, Ji Youn Lee, Robert R. Luedtke, Robert H. Mach +1 more

Data from Use of Multifunctional Sigma-2 Receptor Ligand Conjugates to Trigger Cancer-Selective Cell Death Signaling

(2023)10.1158/0008-5472.c.6503079.v1

N/A

0DataRank · unranked

0 citations

Peter O. Simon, Hiroyuki Kashiwagi, Jinbin Xu, Chenbo Zeng, Suwanna Vangveravong +9 more

Selective Activation of D3 Dopamine Receptors Ameliorates DOI-Induced Head Twitching Accompanied by Changes in Corticostriatal Processing

International Journal of Molecular Sciences(2023)10.3390/ijms24119300

N/A

0DataRank · unranked

0 citations

Claudia Rangel‐Barajas, Andrew Howe, Scott J. Barton, Robert H. Mach, Robert R. Luedtke +2 more

Development of Pyridothiophene Compounds for PET Imaging of α‐Synuclein

Chemistry - A European Journal(2024)10.1002/chem.202303921

N/A

0DataRank · unranked

12 citations

Junchao Tong, Saritha Birudaraju, Yogeshkumar S. Munot, Steven H. Liang, Dinahlee Saturnino Guarino +4 more

Automation of simplified two-step radiolabeling via ditosylate synthon for 18F-labeled radiotracers using AllinOne module

Nuclear Medicine and Biology(2024)10.1016/j.nucmedbio.2024.108948

N/A

0DataRank · unranked

4 citations

Alexander Schmitz, Yu-Ting Lu, Rammyani Pal, Swarbhanu Sarkar, Mark A. Sellmyer +3 more

Monitoring mRNA vaccine antigen expression in vivo using PET/CT

Nature Communications(2025)10.1038/s41467-025-57446-w

N/A

0DataRank · unranked

17 citations

Garima Dwivedi, Yi‐Gen Pan, Catherine Hou, Jean M. Etersque, Hooda Said +11 more

The development of a PET radiotracer for imaging alpha synuclein aggregates in Parkinson's disease

RSC Medicinal Chemistry(2025)10.1039/d5md00057b

N/A

0DataRank · unranked

9 citations

Chia‐Ju Hsieh, Dinahlee Saturnino Guarino, Thomas J. A. Graham, Zsofia Lengyel‐Zhand, Alexander Schmitz +17 more

Genetic code expansion and enzymatic modifications as accessible methods for studying site‐specific post‐translational modifications of alpha‐synuclein and tau

Protein Science(2025)10.1002/pro.70302

N/A

0DataRank · unranked

4 citations

Marie Shimogawa, Jennifer Ramirez, Bernard Abakah, Yarra Venkatesh, Honey Priya James +13 more

Pilot Study of [11C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer

Cells(2025)10.3390/cells14151157

N/A

0DataRank · unranked

3 citations

Dinahlee Saturnino Guarino, Anthony J. Young, Andrew Siderowf, Ilya M. Nasrallah, Alexander Schmitz +7 more

Interactions of Neurodegenerative Disease Positron Emission Tomography Imaging Probe Candidates with the C‐Terminus of α‐Synuclein Fibrils

ChemBioChem(2025)10.1002/cbic.202500578

N/A

0DataRank · unranked

2 citations

Ryann M. Perez, Marshall G. Lougee, Vinayak Vishnu Pagar, Hee Jong Kim, Ho Young Kim +4 more

Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence

Cancer Research Communications(2025)10.1158/2767-9764.crc-23-0562

N/A

0DataRank · unranked

2 citations

Tien-Chi Pan, Dhruv K. Pant, Melissa A. Troester, Andrew V. Kossenkov, David A. Mankoff +3 more

Novel Non-Invasive PET Imaging of Reactive Oxygen Species Using [18 F]ROStrace in Three Proteinopathy-Associated Neurodegenerative Mouse Models

Academic Radiology(2025)10.1016/j.acra.2025.07.061

N/A

0DataRank · unranked

2 citations

Meagan J. McManus, Robert H. Mach, Yi Zhu

Discovery of N-(6-Methoxypyridin-3-yl)quinoline-2-amine Derivatives for Imaging Aggregated α-Synuclein in Parkinson’s Disease with Positron Emission Tomography

Cells(2025)10.3390/cells14141108

N/A

0DataRank · unranked

1 citations

Tianyu Huang, Dhruva D. Dhavale, Jennifer Y. O’Shea, Zsofia Lengyel‐Zhand, Dinahlee Saturnino Guarino +15 more

Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue

Cells(2025)10.3390/cells14181477

N/A

0DataRank · unranked

1 citations

Dhruva D. Dhavale, Helen Hwang, Zachary Smith, Thomas J. A. Graham, Robert H. Mach +2 more

Complementary Structural and Chemical Biology Methods Reveal the Basis for Selective Radioligand Binding to α-Synuclein in MSA Tissue

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.30.662461

N/A

0DataRank · unranked

4 citations

Ryann M. Perez, Dinahlee Saturnino Guarino, Dhruva Dhavala, Joseph K. Baumgardt, Kyle D. Shaffer +5 more

Genetic Code Expansion and Enzymatic Modifications as Accessible Methods for Studying Site-Specific Post-Translational Modifications of Alpha-Synuclein and Tau

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.16.654576

N/A

0DataRank · unranked

0 citations

Marie Shimogawa, Jennifer Ramirez, Bernard Abakah, Yarra Venkatesh, Honey Priya James +12 more

Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening

Chemical Science(2020)10.1039/d0sc02159h

N/A

0DataRank · unranked

58 citations

Zsofia Lengyel‐Zhand, Bieneke Janssen, Marshall G. Lougee, Sam Giannakoulias, Chia‐Ju Hsieh +8 more

Optical Redox Imaging of Breast Cancer NADH Redox Status Associated with PGC1α Gene Expression

Academic Radiology(2025)10.1016/j.acra.2025.11.014

N/A

0DataRank · unranked

0 citations

Yu Wen, He N. Xu, Lijun Zhang, Chenbo Zeng, Tony Lin +4 more

Ligand with Two Modes of Interaction with the Dopamine D2 Receptor–An Induced-Fit Mechanism of Insurmountable Antagonism

ACS Chemical Neuroscience(2020)10.1021/acschemneuro.0c00477

N/A

0DataRank · unranked

13 citations

Hugo Zeberg, Tomasz Maciej Stępniewski, R. Benjamin Free, Sean W. Reilly, Robert R. Luedtke +8 more

Synthesis and characterization of high affinity fluorogenic α-synuclein probes

Chemical Communications(2020)10.1039/c9cc09849f

N/A

0DataRank · unranked

37 citations

John J. Ferrie, Bieneke Janssen, Chia‐Ju Hsieh, Thomas J. A. Graham, Kui-ying Xu +6 more