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Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue

Cells(2025)10.3390/cells14181477Source: DataRank Database

Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue is a research paper published in Cells (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (10 grants)OA: goldTopics (58)IDs (PubMed, PMC)Annotations (1)

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Authors (7)

Dhruva D. Dhavale ORCID,Helen Hwang ORCID,Zachary Smith ORCID,Thomas J. A. Graham ORCID,Robert H. Mach ORCID

Live enrichment

PubMed:41002442 PMC:PMC12468313

National Institutes of Health

Grant: NS110456

National Institutes of Health

Grant: NS110436

NIH HHS

Grant: 2RF1NS110436-06

NIH HHS

Grant: 1U19NS110456-05

Michael J. Fox Foundation

Grant: Consortium to Develop an Alpha-synuclein Imaging Agent

NINDS NIH HHS

Grant: U19 NS110456

NINDS NIH HHS

Grant: RF1 NS110436

NINDS NIH HHS

Grant: U01 NS110436

National Institutes of Health

Grant: 5U19NS110456-04

Center without Walls for Imaging Proteinopathies with PET (CW2IP2)

National Institutes of Health

Grant: 5U01NS110436-05

STRUCTURAL BIOLOGY OF ALPHA-SYNUCLEIN IN LEWY BODY DEMENTIA

goldLicense: cc-by

publisherhttps://www.mdpi.com/2073-4409/14/18/1477/pdf?version=1758535757

publisherhttps://www.mdpi.com/2073-4409/14/18/1477/pdf

repositoryhttps://doaj.org/article/154bfc3e6c1b4c91888add03ff8c2e5a

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12468313

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12468313/

Fields of Study

03 medical and health sciences0302 clinical medicineHumansAutoradiographyalpha-SynucleinLewy Body DiseaseBrainProtein BindingAgedMolecular Docking SimulationMaleAutopsyPositron-Emission TomographyFemaleLewy BodiesAged, 80 and overLigandsRadioligand Assay

MeSH Terms

BrainLewy BodiesHumansLewy Body DiseaseLigandsPositron-Emission TomographyRadioligand AssayAutopsyAutoradiographyProtein BindingAgedAged, 80 and overFemaleMalealpha-SynucleinMolecular Docking Simulation

Keywords

AutoradiographyParkinson’s DiseaseRadioligand BindingLewy Body DementiaFibril StructureAlpha-synuclein FibrilsAmplified Lbd FibrilsTg-1-90bLewy Body DiseaseMaleAged, 80 and overBrainLigandsArticleMolecular Docking SimulationRadioligand AssayPositron-Emission Tomographyalpha-SynucleinHumansFemaleLewy BodiesAutopsyProtein BindingAged

Use of Amplified Lewy Body Dementia Fibrils and Autoradiography to Characterize Binding of Radioligand Tg-1-90B to Alpha-Synuclein Fibrils in Postmortem Brain Tissue

FAIR Checklist

Authors (7)

Funding (10 grants)

Open Access

Topics

Annotations (Europe PMC)