Gregory R. J. Thatcher

Also affiliated with Department of Physics, Mathematics and Informatics

Biochemistry, Genetics and Molecular BiologyMedicineComputer ScienceChemistryPharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 24 papers. Top paper: “Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections”.

Discovery and Structural Optimization of 4-(Aminomethyl)benzamides as Potent Entry Inhibitors of Ebola and Marburg Virus Infections

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00463

N/A

0.524DataRank · unranked

32 citations

Norton P. Peet, Letitia Wong, Adam M. Schafer, Han Cheng, Manu Anantpadma +4 more

Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00456

N/A

0DataRank · unranked

36 citations

Jiong Zhao, Lauren M. Gutgesell, Zhengnan Shen, Kiira Ratia, Katherine Dye +7 more

Interaction of oxidative stress and neurotrauma in ALDH2 mice causes significant and persistent behavioral and pro-inflammatory effects in a tractable model of mild traumatic brain injury

Redox Biology(2020)10.1016/j.redox.2020.101486

N/A

0DataRank · unranked

24 citations

Sue Lee, Michael A. R. Hollas, Emily Nepomuceno, David González, Kevin A. Tam +6 more

Design of SARS-CoV-2 PLpro Inhibitors for COVID-19 Antiviral Therapy Leveraging Binding Cooperativity

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01307

N/A

0DataRank · unranked

211 citations

Kiira Ratia, Laura Cooper, Deyu Kong, Hyun Lee, Youngjin Kwon +8 more

MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3

Oncogene(2021)10.1038/s41388-021-02007-w

N/A

0DataRank · unranked

38 citations

Sandeep Kumar, Navin Viswakarma, Daniel R. Principe, Subhasis Das, Gautam Sondarva +8 more

Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

PLoS Pathogens(2021)10.1371/journal.ppat.1009312

N/A

0DataRank · unranked

33 citations

Rui Xiong, Laura Cooper, Raghad Nowar, Hyun Lee, Yangfeng Li +8 more

Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development

EBioMedicine(2021)10.1016/j.ebiom.2021.103287

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0DataRank · unranked

31 citations

Md. Wasim Khan, Manel Benaissa, Oleksii Dubrovskyi, Martha Ackerman-Berrier, Mary Jo LaDu +3 more

Extending the Calpain–Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma

ACS Pharmacology & Translational Science(2021)10.1021/acsptsci.0c00217

N/A

0DataRank · unranked

14 citations

Ammar Jastaniah, Oleksii Dubrovskyi, Irina N. Gaisina, Leon M. Tai, Gregory R. J. Thatcher +1 more

Systemic Candesartan Treatment Modulates Behavior, Synaptic Protein Levels, and Neuroinflammation in Female Mice That Express Human APOE4

Frontiers in Neuroscience(2021)10.3389/fnins.2021.628403

N/A

0DataRank · unranked

11 citations

Steve Zaldua, Adedoyin Dada, Kateryna Krochmaliuk, Katherine Dye, Felecia M. Marottoli +3 more

Remembering your A, B, C's: Alzheimer's disease and ABCA1

Acta Pharmaceutica Sinica B(2022)10.1016/j.apsb.2022.01.011

N/A

0DataRank · unranked

76 citations

Megan S. Laham, Gregory R. J. Thatcher, Cutler T. Lewandowski

Structure–Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors

Antioxidants(2022)10.3390/antiox11020220

N/A

0DataRank · unranked

8 citations

С. В. Никулин, Dmitry M. Hushpulian, A. Yu. Khristichenko, A. I. Osipyants, Andrey F. Asachenko +13 more

The mechanism of nicotinamide phosphoribosyltransferase whereby positive allosteric modulation elevates cellular NAD +

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.21.513220

N/A

0DataRank · unranked

1 citations

Zhengnan Shen, Jesse Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider +10 more

Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer

Molecular Pharmacology(2020)10.1124/molpharm.120.000054

N/A

0DataRank · unranked

21 citations

Philipp Y. Maximov, Ramona Curpăn, Jay S. Hanspal, Ping Fan, Rui Xiong +4 more

Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD+

Biochemistry(2023)10.1021/acs.biochem.2c00655

N/A

0DataRank · unranked

19 citations

Zhengnan Shen, Jesse Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider +10 more

Synthesis, Optimization, and Structure–Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs)

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01406

N/A

0DataRank · unranked

17 citations

Kiira Ratia, Isabella S. Krider, Martha Ackerman-Berrier, Christopher Penton, Soumya Reddy Musku +10 more

The “Doorstop Pocket” In Thioredoxin Reductases─An Unexpected Druggable Regulator of the Catalytic Machinery

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00669

N/A

0DataRank · unranked

16 citations

Sammy Y. Aboagye, Valentina Petukhova, Irida Kastrati, Rodolfo Ippoliti, Gregory R. J. Thatcher +4 more

Nonlipogenic ABCA1 Inducers (NLAI) for Alzheimer’s Disease Validated in a Mouse Model Expressing Human APOE3/APOE4

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00733

N/A

0DataRank · unranked

13 citations

Megan S. Laham, Cutler T. Lewandowski, Ana C. Valencia‐Olvera, Deebika Balu, Annabelle Moore +9 more

Channeling Nicotinamide Phosphoribosyltransferase (NAMPT) to Address Life and Death

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c02112

N/A

0DataRank · unranked

21 citations

Isabella S. Krider, Erick T. M. Alves, Jenna M. Courey, Megan S. Laham, Gregory R. J. Thatcher +1 more

Structure-Guided Design and Synthesis of Pyridinone-Based Selective Bromodomain and Extra-Terminal Domain (BET)-First Bromodomain (BD1) Inhibitors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c01837

N/A

0DataRank · unranked

15 citations

Zhengnan Shen, Kiira Ratia, Jiong Zhao, Fei Huang, Oleksii Dubrovyskyii +6 more

Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.3c00391

N/A

0DataRank · unranked

7 citations

Kiira Ratia, Victoria Weidig, Velma Ganga Reddy, Martha Ackerman-Berrier, Christopher Penton +6 more

Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy

Frontiers in Endocrinology(2024)10.3389/fendo.2024.1374825

N/A

0DataRank · unranked

5 citations

Ana C. Valencia‐Olvera, Ashwini Deshpande, Saharsh Narayanam, Sravya Konasani, Shreya Pattisapu +5 more

In search of nonlipogenic ABCA1 inducers (NLAI): precision coregulator TR-FRET identifies diverse signatures for LXR ligands

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.12.675753

N/A

0DataRank · unranked

1 citations

Martha Ackerman-Berrier, Fahmida Alam, Sarah Turner, Ganga Reddy Velma, Christopher Penton +8 more

Exploration of precision coregulator TR-FRET identifies diverse signatures for LXR ligands relevant to discovery of nonlipogenic ABCA1 inducers

eLife(2025)10.7554/elife.109146

N/A

0DataRank · unranked

0 citations

Martha Ackerman-Berrier, Fahmida Alam, Sarah Turner, Velma Ganga Reddy, Christopher Penton +8 more

Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo

Nature Communications(2023)10.1038/s41467-023-39444-y

N/A

0DataRank · unranked

37 citations

Samuel Yaw Aboagye, Matteo Ardini, Rachel Lullo, Francesca Fata, Margaret E. Byrne +16 more