Jason W. Locasale

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 53 papers. Top paper: “GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis”.

GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis

Nature Communications(2023)10.1038/s41467-023-43889-6

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1.0DataRank · unranked

39 citations

Matthew E. Combs, Juan Liu, Xue Bai, Wenbo B. Wang, Laura E. Herring +8 more

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

Nature Neuroscience(2017)10.1038/nn.4537

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0.808DataRank · unranked

218 citations

Kailin Yang, Qi Xie, Qiulian Wu, Stephen C. Mack, Yu Shi +19 more

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism

Nature Metabolism(2020)10.1038/s42255-020-0191-z

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0DataRank · unranked

218 citations

Nina Marie G. Garcia, Brock J. McKinney, Ryan Lupo, Laura Noteware, Rachel Newcomb +5 more

HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer

Nature Communications(2020)10.1038/s41467-020-17818-w

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0DataRank · unranked

128 citations

Yuanyuan Li, Xia Gao, Kai Kang, Jason G. Williams, Lingfeng Tong +9 more

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Nature Genetics(2020)10.1038/s41588-020-0590-9

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0DataRank · unranked

91 citations

Justine C. Rutter, Abigail Xie, Bryann Pardieu, Emily T. Winn, Reinaldo Dal Bello +14 more

The Molecular Link from Diet to Cancer Cell Metabolism

Molecular Cell(2020)10.1016/j.molcel.2020.05.018

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0DataRank · unranked

91 citations

Annamarie E. Allen, Jason W. Locasale, Shree Bose

SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease

Nature Communications(2020)10.1038/s41467-020-19743-4

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0DataRank · unranked

81 citations

Sanna Matilainen, Jesse G. Meyer, Pieti W. Pallijeff, J. Wall Richard, Christopher J. Carroll +21 more

Quantitative Analysis of the Physiological Contributions of Glucose to the TCA Cycle

Cell Metabolism(2020)10.1016/j.cmet.2020.09.005

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0DataRank · unranked

58 citations

Ziwei Dai, Daniel E. Cooper, David G. Kirsch, Jason W. Locasale, Shiyu Liu

Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion

Nature Communications(2020)10.1038/s41467-020-16220-w

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0DataRank · unranked

52 citations

James A. Saba, Cong-Hui Yao, Michael A. Hilzendeger, Anna Drangowska-Way, Chintan Joshi +8 more

Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney

Disease Models & Mechanisms(2020)10.1242/dmm.045898

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0DataRank · unranked

18 citations

Hyeyoung Nam, Eun‐Hee Shim, Richard Kirkman, Anirban Kundu, Suman Karki +13 more

Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration

iScience(2020)10.1016/j.isci.2020.100858

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0DataRank · unranked

12 citations

Juan Liu, Jason W. Locasale, Barbara E. Corkey, Jude T. Deeney, Lucia E. Rameh +1 more

Dietary Methionine in T Cell Biology and Autoimmune Disease

Cell Metabolism(2020)10.1016/j.cmet.2020.01.007

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0DataRank · unranked

11 citations

Xiaoling Li, Jason W. Locasale, Shuang Tang

The Na + /K + ATPase Regulates Glycolysis and Modifies Immune Metabolism in Tumors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.31.018739

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0DataRank · unranked

8 citations

Zhengtao Xiao, Amy J. Wisdom, Shree Bose, Maria V. Liberti, Michael A. Reid +5 more

Cellular Stress Signaling Activates Type-I IFN Response Through FOXO3-regulated Lamin Posttranslational Modification

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.03.075143

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0DataRank · unranked

6 citations

Ziwei Dai, Fei Li, Teresa Sánchez, Jason W. Locasale, Lewis L Cantley +3 more

Cooperative virus propagation in COVID-19 transmission

medRxiv(2020)10.1101/2020.05.05.20092361

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0DataRank · unranked

4 citations

Jason W. Locasale, Ziwei Dai

AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival

UNC Libraries(2020)10.17615/txt4-6h55

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0DataRank · unranked

0 citations

Pankuri Goraksha-Hicks, Andrew N. Macintyre, Amanda Nichols, Peter J. Siska, Carson E. Barnes +13 more

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

UNC Libraries(2020)10.17615/1ca2-0y14

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0DataRank · unranked

0 citations

Rachael Baker, Lewis C. Cantley, Emily Wilkerson, Steven M. Lewis, Brian Kuhlman +4 more

Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity

Nature Immunology(2021)10.1038/s41590-021-01047-4

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0DataRank · unranked

209 citations

Chin-Hsien Tsai, Héctor Gallart‐Ayala, Yi-Ru Yu, Fabien Franco, Léa Zaffalon +14 more

A glutaminase isoform switch drives therapeutic resistance and disease progression of prostate cancer

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2012748118

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0DataRank · unranked

73 citations

Yu Yin, Yanjing Li, Xufeng Chen, Yan Chang, Hong Zhang +16 more

Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification

Nature Communications(2021)10.1038/s41467-020-20839-0

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0DataRank · unranked

62 citations

Hiroki Uchida, Ziwei Dai, Fei Li, Teresa Sánchez, Jason W. Locasale +4 more

The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer

JCI Insight(2021)10.1172/jci.insight.148438

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0DataRank · unranked

36 citations

Anirban Kundu, Suman Karki, Garrett J. Brinkley, Darshan S. Chandrashekar, Richard Kirkman +7 more

Metabolic supervision by PPIP5K, an inositol pyrophosphate kinase/phosphatase, controls proliferation of the HCT116 tumor cell line

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2020187118

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0DataRank · unranked

34 citations

Juan Liu, Xiaojing Liu, Haibo Zhang, Ji Luo, Huanchen Wang +3 more

Rethinking the bioavailability and cellular transport properties of S-adenosylmethionine

Cell Stress(2021)10.15698/cst2022.01.261

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0DataRank · unranked

27 citations

Jason W. Locasale, Yudong Sun

Epigenomic links from metabolism—methionine and chromatin architecture

Current Opinion in Chemical Biology(2021)10.1016/j.cbpa.2021.01.011

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0DataRank · unranked

12 citations

Jason W. Locasale, Zhengtao Xiao

Dietary methionine restriction impairs anti-tumor immunity through gut microbiota

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.27.457955

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0DataRank · unranked

6 citations

Xiaojiang Xu, Qing Xu, Xin Xu, M. Andrea Azcárate-Peril, Xiaoyue Wu +6 more

TGF-β signaling suppresses TCA cycle metabolism in renal cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.19.429599

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0DataRank · unranked

5 citations

Anirban Kundu, Suman Karki, Garrett J. Brinkley, Darshan S. Chandrashekar, Richard Kirkman +7 more

Amino acid variability, tradeoffs and optimality in human diet

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.16.448627

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3 citations

Jason W. Locasale, Ziwei Dai

Predictive targeting of mitochondrial metabolism in Acute Myeloid Leukemia patients with a lipoic acid analog

medRxiv(2021)10.1101/2021.06.03.21257935

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0DataRank · unranked

1 citations

Shree Bose, Kristin M. Pladna, Rebecca G. Anderson, Peter G. Mikhael, Zhengtao Xiao +6 more

Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.02.462869

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0DataRank · unranked

1 citations

Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Likun Duan +13 more

13 C tracer analysis identifies extensive recycling of endogenous CO 2 in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.04.429777

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0DataRank · unranked

0 citations

Daniel E. Cooper, Grace Scheidemantle, Jason W. Locasale, David G. Kirsch, Xiaojing Liu +1 more

Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila

Nature(2022)10.1038/s41586-022-04960-2

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0DataRank · unranked

59 citations

Patrick Jouandin, Pranav V. Lalgudi, Rich Binari, Max L. Valenstein, Michael A. Reid +6 more

Amino acid variability, tradeoffs and optimality in human diet

Nature Communications(2022)10.1038/s41467-022-34486-0

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0DataRank · unranked

58 citations

Weiyan Zheng, Jason W. Locasale, Ziwei Dai

13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo

Cancer & Metabolism(2022)10.1186/s40170-022-00287-8

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0DataRank · unranked

32 citations

Daniel E. Cooper, Grace Scheidemantle, Jason W. Locasale, David G. Kirsch, Xiaojing Liu +1 more

Diet and Exercise in Cancer Metabolism

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0096

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0DataRank · unranked

30 citations

Jason W. Locasale

Regulation of urea cycle by reversible high stoichiometry lysine succinylation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.24.497535

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0DataRank · unranked

1 citations

Xueshu Xie, Chris Carrico, Jesse G. Meyer, Lei Wei, Joanna Bons +11 more

Nucleotide metabolism is linked to cysteine availability

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.30.510321

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0DataRank · unranked

0 citations

Yudong Sun, Fangchao Wei, Michael A. Reid, Jason W. Locasale, Annamarie E. Allen

Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells

Cancer Discovery(2023)10.1158/2159-8290.cd-23-0334

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0DataRank · unranked

58 citations

Dezhen Wang, Surendra K. Shukla, Tuo Hu, Ravi Thakur, Xiao Fu +13 more

Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

Cell Reports(2023)10.1016/j.celrep.2022.111941

N/A

0DataRank · unranked

51 citations

Zhan Wang, Wenzheng Han, Qingxia Zhao, Manal Zabalawi, Likun Duan +13 more

Methionine restriction and antitumor immunity

Trends in cancer(2023)10.1016/j.trecan.2023.07.008

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0DataRank · unranked

18 citations

Jason W. Locasale, Fangchao Wei

Nucleotide metabolism is linked to cysteine availability

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.103039

N/A

0DataRank · unranked

9 citations

Yudong Sun, Fangchao Wei, Michael A. Reid, Jason W. Locasale, Annamarie E. Allen

Methionine availability influences essential H3K36me3 dynamics during cell differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.22.568331

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0DataRank · unranked

4 citations

Vijyendra Ramesh, Fangchao Wei, Jason W. Locasale, Yudong Sun

Data from Epigenetic Switch–Induced Viral Mimicry Evasion in Chemotherapy-Resistant Breast Cancer

(2023)10.1158/2159-8290.c.6547796.v1

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0DataRank · unranked

0 citations

Seyed Ali Madani Tonekaboni, Giacomo Grillo, Constanza Martínez, Yunchi Ingrid Kao, Felicia Tai +18 more

Uncoupling of lifespan and reproductive tradeoffs by dietary methionine and one-carbon metabolism

Research Square(2023)10.21203/rs.3.rs-3031504/v1

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0DataRank · unranked

0 citations

Shiyu Liu, Juan Liu, Annamarie E. Allen, Michael A. Reid, Jason W. Locasale +1 more

Embracing cancer complexity: Hallmarks of systemic disease

Cell(2024)10.1016/j.cell.2024.02.009

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0DataRank · unranked

481 citations

Elsa Bernard, Chris Abbosh, Fabrice Andre, Johan Auwerx, Allan Balmain +28 more

Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function

Science(2024)10.1126/science.adk9167

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0DataRank · unranked

56 citations

Shan Kuang, Kaitlin Watrud, Mary R. Doherty, Charlotte Gineste, Grinu Mathew +40 more

Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2

Cell Metabolism(2024)10.1016/j.cmet.2024.09.014

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0DataRank · unranked

31 citations

Deobrat Dixit, Andrea Cruz, Leo J.Y. Kim, Likun Duan, Xin Xu +18 more

Regulation of urea cycle by reversible high-stoichiometry lysine succinylation

Nature Metabolism(2024)10.1038/s42255-024-01005-y

N/A

0DataRank · unranked

21 citations

Jingqi Fang, Xueshu Xie, Chris Carrico, Jesse G. Meyer, Lei Wei +13 more

Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia

Cancer Research(2024)10.1158/0008-5472.can-23-0291

N/A

0DataRank · unranked

13 citations

Haley E. Ramsey, Alexander J. Silver, Donovan Brown, Dalton Greenwood, Brianna N. Smith +12 more

Targeting glutamine metabolism improves sarcoma response to radiation therapy in vivo

Communications Biology(2024)10.1038/s42003-024-06262-x

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0DataRank · unranked

10 citations

Daniel E. Cooper, Kushal T. Kadakia, Annamarie E. Allen, Likun Duan, Lixia Luo +5 more

l-2-Hydroxyglutarate remodeling of the epigenome and epitranscriptome creates a metabolic vulnerability in kidney cancer models

Journal of Clinical Investigation(2024)10.1172/jci171294

N/A

0DataRank · unranked

7 citations

Garrett J. Brinkley, Hyeyoung Nam, Suman Karki, Richard Kirkman, Madhuparna Pandit +18 more

Diet and Cancer Metabolism

Cold Spring Harbor Perspectives in Medicine(2024)10.1101/cshperspect.a041549

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0DataRank · unranked

11 citations

Marcus D. Goncalves, Maira Di Tano, Guillermo Burgos-Barragan, Jason W. Locasale

Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

UNC Libraries(2024)10.17615/cca8-2d34

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0DataRank · unranked

0 citations

Xi Chen, Baek Kim, Charles M. Perou, T.S Ptacek, Jean-Marc Simon +16 more

Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway

Cell Metabolism(2020)10.1016/j.cmet.2020.02.001

N/A

0DataRank · unranked

235 citations

Jason G. Williams, Juan Liu, Mikhail V. Makarov, Xiaoyue Wu, Fred B. Lih +15 more