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Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

Nature Neuroscience(2017)10.1038/nn.4537Source: DataRank Database

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma is a research paper published in Nature Neuroscience (2017). On theSindex it has a DataRank of 0.808. It has been cited 218 times.

N/A

0.808DataRank · unranked

Scored on demand from live citation data

218 citations

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Linked data & code

geo gen

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 6.28)OA: closedTopics (44)Linked Datasets (6)DataCite Reuse (6)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (0/2)

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.808

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (24)

Kailin Yang ORCID,Qi Xie ORCID,Qiulian Wu ORCID,Stephen C. Mack ORCID,Yu Shi ORCID

Live enrichment

PubMed:28346452 PMC:PMC6015494 OpenAlex:https://openalex.org/W2602955340

NINDS NIH HHS

Grant: K02 NS047409

NCI NIH HHS

Grant: R01 CA154130

NCI NIH HHS

Grant: R35 CA197718

NINDS NIH HHS

Grant: R01 NS091080

NCI NIH HHS

Grant: R01 CA169117

NINDS NIH HHS

Grant: R01 NS087913

NCI NIH HHS

Grant: R21 CA201963

NCATS NIH HHS

Grant: UL1 TR000439

NCI NIH HHS

Grant: F30 CA203101

Intramural NIH HHS

Grant: Z99 CA999999

NCI NIH HHS

Grant: R01 CA116659

NCI NIH HHS

Grant: R01 CA184090

NINDS NIH HHS

Grant: R01 NS103434

NINDS NIH HHS

Grant: R01 NS089272

NIGMS NIH HHS

Grant: T32 GM007250

NCI NIH HHS

Grant: R00 CA168997

NCI NIH HHS

Grant: R01 CA129958

NCI NIH HHS

Grant: R01 CA171652

NCI NIH HHS

Grant: R01 CA193256

FWCI

6.28

Citation Percentile

1.0%

Citation Trend

2017

2018

2019

2020

2021

2022

2023

2024

2025

2026

closedLicense: http://www.springer.com/tdm

publisherhttp://www.nature.com/articles/nn.4537.pdf

publisherhttp://www.nature.com/articles/nn.4537

publisherhttp://www.nature.com/doifinder/10.1038/nn.4537

journalhttps://doi.org/10.1038/nn.4537

repositoryhttps://pubmed.ncbi.nlm.nih.gov/28346452

Fields of Study

Histone Deacetylase Inhibitors ResearchGlioma Diagnosis and TreatmentEpigenetics and DNA MethylationAdenosine MonophosphateCell ProliferationCells, CulturedGenomicsGliomaGlycolysisGuanosine MonophosphateHumansMetabolomicsNeoplastic Stem CellsProto-Oncogene Proteins c-mycPurinesRibose-Phosphate PyrophosphokinaseUp-Regulation

MeSH Terms

Adenosine MonophosphateCells, CulturedGliomaGlycolysisGuanosine MonophosphateHumansPurinesRibose-Phosphate PyrophosphokinaseNeoplastic Stem CellsUp-RegulationProto-Oncogene Proteins c-mycGenomicsCell ProliferationMetabolomics

Keywords

BiologyGliomaPurineCancer cellPurine metabolismMetabolomicsBiochemistryCancer researchCell biologyCancerEnzymeBioinformaticsGenetics

Sustainable Development Goals

SDG 0: Affordable and clean energy

Additional file 1 of G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

10.6084/m9.figshare.25566286.v1figshare

Additional file 1 of G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

10.6084/m9.figshare.25566286figshare

Additional file 2 of G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

10.6084/m9.figshare.25566391.v1figshare

Additional file 2 of G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

10.6084/m9.figshare.25566391figshare

Additional file 3 of G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

10.6084/m9.figshare.26703733.v1figshare

Additional file 3 of G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway

10.6084/m9.figshare.26703733figshare