Mathew Blurton-Jones

NeuroscienceMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE

The Journal of Experimental Medicine(2020)10.1084/jem.20200474

Top 11%

2.0DataRank

Top 11%73 citations

Bing Zhu, Yan Liu, Xiaoming Zhang, Jun Yin, Xiaoguang Li +11 more

Papers

Driven by 45 papers — median percentile 89. Top paper: “Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE”.

Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE

The Journal of Experimental Medicine(2020)10.1084/jem.20200474

Top 11%

2.0DataRank

Top 11%73 citations

Bing Zhu, Yan Liu, Xiaoming Zhang, Jun Yin, Xiaoguang Li +11 more

TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

eLife(2022)10.7554/elife.73021

N/A

1.6DataRank · unranked

61 citations

Amanda McQuade, Alberto Granzotto, You Jung Kang, Jean Paul Chadarevian, Sunil Gandhi +8 more

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease

Nature(2025)10.1038/s41586-025-08852-z

N/A

0.998DataRank · unranked

64 citations

Ayshwarya Subramanian, Zhuoran Yin, Ahad Khalilnezhad, Yufan Wu, Danyang He +38 more

Microglial APOE3 Christchurch protects neurons from Tau pathology in a human iPSC-based model of Alzheimer’s disease

Cell Reports(2024)10.1016/j.celrep.2024.114982

N/A

0.701DataRank · unranked

25 citations

Cheng Wang, Randall C. Mazzarino, Paula Perez‐Corredor, Hayk Davtyan, Mathew Blurton-Jones +4 more

Cerebrovascular alterations in a mouse model of late-onset Alzheimer’s disease

Neurophotonics(2025)10.1117/1.nph.12.s1.s14614

N/A

0.104DataRank · unranked

1 citations

Danny F. Xie, Maiella Nona Laquindanum Nuqui, Jonathan Hasselman, Thinh Phan, Robert H. Wilson +13 more

Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation

Communications Biology(2021)10.1038/s42003-021-02229-4

N/A

0DataRank · unranked

51 citations

Samuel Rodriguez, Jennifer Luong, Shiri Li, Rui Cao, Hamad Alshetaiwi +10 more

TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.24.457491

N/A

0DataRank · unranked

2 citations

Amanda McQuade, Alberto Granzotto, You Jung Kang, Jean Paul Chadarevian, Sunil Gandhi +8 more

Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice

Cell Reports(2022)10.1016/j.celrep.2022.110961

N/A

0DataRank · unranked

184 citations

Samuel Morabito, Emma Danhash, Amanda McQuade, Jessica Sanchez, Emily Miyoshi +16 more

Engineering an inhibitor-resistant human CSF1R variant for microglia replacement

The Journal of Experimental Medicine(2022)10.1084/jem.20220857

N/A

0DataRank · unranked

95 citations

Sonia I Lombroso, Graham C. Peet, Jonathan Hasselmann, Christina Tu, Dave E. Marzan +17 more

The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model

Alzheimer s & Dementia(2022)10.1002/alz.12577

N/A

0DataRank · unranked

54 citations

Whitney England, Emma Danhash, Sepideh Kiani Shabestari, Amit Jairaman, Jean Paul Chadarevian +14 more

Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits

iScience(2022)10.1016/j.isci.2022.105732

N/A

0DataRank · unranked

29 citations

Edsel M. Abud, Mara S. Burns, Jie Wu, Sarah Hernandez, Nicolette R. McClure +14 more

RETRACTED ARTICLE: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies

npj Vaccines(2022)10.1038/s41541-021-00424-2

N/A

0DataRank · unranked

20 citations

Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan +12 more

Using Advanced Diffusion-Weighted Imaging to Predict Cell Counts in Gray Matter: Potential and Pitfalls

Frontiers in Neuroscience(2022)10.3389/fnins.2022.881713

N/A

0DataRank · unranked

12 citations

Sepideh Kiani Shabestari, Mathew Blurton-Jones, André Obenaus, Craig E.L. Stark, Hamsanandini Radhakrishnan

Immunogenicity of MultiTEP-Platform-Based Recombinant Protein Vaccine, PV-1950R, Targeting Three B-Cell Antigenic Determinants of Pathological α-Synuclein

International Journal of Molecular Sciences(2022)10.3390/ijms23116080

N/A

0DataRank · unranked

8 citations

Gor Chailyan, Armine Hovakimyan, Tatevik Antonyan, Sepideh Kiani Shabestari, Irina Petrushina +7 more

A resource for generating and manipulating human microglial states in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.02.490100

N/A

0DataRank · unranked

11 citations

Martine Therrien, Saša Jereb, Tushar Kamath, Trevor Atkeson, Samuel E. Marsh +18 more

Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.23.509276

N/A

0DataRank · unranked

2 citations

Nicholas J. Fiore, Yang Zhang, Yuka Milton, Marilyn Kelly, Marly Coe +12 more

Integrated transcriptome analysis of Huntington’s disease iPSC-derived and mouse astrocytes implicates dysregulated synaptogenesis, actin, and astrocyte maturation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.28.501170

N/A

0DataRank · unranked

1 citations

Edsel M. Abud, Mara S. Burns, Jie Wu, Sarah Hernandez, Nicolette R. Geller +14 more

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro

Nature Immunology(2023)10.1038/s41590-023-01558-2

N/A

0DataRank · unranked

154 citations

Martine Therrien, Saša Jereb, Tushar Kamath, Vahid Gazestani, Trevor Atkeson +19 more

Human microglia maturation is underpinned by specific gene regulatory networks

Immunity(2023)10.1016/j.immuni.2023.07.016

N/A

0DataRank · unranked

63 citations

Rick Z. Li, Emily A. Hansen, Samantha Trescott, Bethany Fixsen, Celina T. Nguyen +31 more

Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis

Nature Cell Biology(2023)10.1038/s41556-023-01273-y

N/A

0DataRank · unranked

56 citations

Kerrigan Blake, Aaron Longworth, Morgan Coburn, Jacob Insua‐Rodríguez, Timothy P McMullen +13 more

Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model

Cell Death and Disease(2023)10.1038/s41419-023-05980-0

N/A

0DataRank · unranked

34 citations

Nicholas J. Fiore, Yang Zhang, Yuka Milton, Marilyn Kelly, Marly Coe +12 more

Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model

Cell Reports(2023)10.1016/j.celrep.2023.112841

N/A

0DataRank · unranked

31 citations

Jianfei Chao, Cheng Wang, Guihua Sun, Daniel Roeth, Wei Liu +9 more

Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features

Frontiers in Cellular Neuroscience(2023)10.3389/fncel.2023.1179796

N/A

0DataRank · unranked

23 citations

Eric Alsop, Jennifer Lévy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow +27 more

CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model

STAR Protocols(2023)10.1016/j.xpro.2023.102490

N/A

0DataRank · unranked

11 citations

Hayk Davtyan, Sonia I Lombroso, F. Chris Bennett, Mathew Blurton-Jones, Jean Paul Chadarevian

Microglial APOE4: more is less and less is more

Molecular Neurodegeneration(2023)10.1186/s13024-023-00693-6

N/A

0DataRank · unranked

11 citations

Mathew Blurton-Jones, Ghazaleh Eskandari-Sedighi

Novel Vaccine against Pathological Pyroglutamate-Modified Amyloid Beta for Prevention of Alzheimer’s Disease

International Journal of Molecular Sciences(2023)10.3390/ijms24129797

N/A

0DataRank · unranked

7 citations

Olga King, Armine Hovakimyan, Irina Petrushina, Tatevik Antonyan, Gor Chailyan +9 more

Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy

Neuron(2024)10.1016/j.neuron.2024.05.023

N/A

0DataRank · unranked

78 citations

Jonathan Hasselmann, Alina Lahian, Joia Kai Capocchi, Adrian Escobar, Tau En Lim +14 more

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease

Nature Medicine(2024)10.1038/s41591-024-03122-3

N/A

0DataRank · unranked

69 citations

Kilian L. Kleemann, Thomas Rust, Madison Carpenter, Madeline Grucci, Michael Aronchik +21 more

Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

Neuron(2024)10.1016/j.neuron.2024.07.015

N/A

0DataRank · unranked

46 citations

Sean Harvey, Kaja Bajc, Tony Z Zhang, Danielle A Jeffrey, Alexander Z Zhang +16 more

Neurotoxic Microglial Activation via IFNγ‐Induced Nrf2 Reduction Exacerbating Alzheimer's Disease

Advanced Science(2024)10.1002/advs.202304357

N/A

0DataRank · unranked

23 citations

Seung Jae Hyeon, Amanda McQuade, Jiwoon Lim, Seung Hyun Baek, Yen N. Diep +8 more

Organelle phenotyping and multi‐dimensional microscopy identify C1q as a novel regulator of microglial function

Journal of Neurochemistry(2024)10.1111/jnc.16173

N/A

0DataRank · unranked

2 citations

Lorenzo Scipioni, J. D. Karam, Zahara Keulen, Mathew Blurton-Jones, Enrico Gratton +2 more

ER and SOCE Ca2+ signals are not required for directed cell migration in human iPSC-derived microglia

Cell Calcium(2024)10.1016/j.ceca.2024.102923

N/A

0DataRank · unranked

3 citations

Amanda McQuade, Jean Paul Chadarevian, Hayk Davtyan, Stefano L. Sensi, Ian Parker +3 more

PILRA regulates microglial neuroinflammation and lipid metabolism as a candidate therapeutic target for Alzheimer’s disease

Research Square(2024)10.21203/rs.3.rs-3954863/v1

N/A

0DataRank · unranked

9 citations

Tanya Weerakkody, Hanna Sabelström, David Tatarakis, Jung H. Suh, Marcus Y. Chin +26 more

ER and SOCE Ca 2+ signals are not required for directed cell migration in human microglia

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.18.576126

N/A

0DataRank · unranked

3 citations

Amanda McQuade, Jean Paul Chadarevian, Hayk Davtyan, Stefano L. Sensi, Ian Parker +3 more

Harnessing human iPSC-microglia for CNS-wide delivery of disease-modifying proteins

Cell stem cell(2025)10.1016/j.stem.2025.03.009

N/A

0DataRank · unranked

44 citations

Hayk Davtyan, Alina L Chadarevian, Jasmine Nguyen, Joia Kai Capocchi, Lauren Le +13 more

Microglia-specific regulation of lipid metabolism in Alzheimer’s disease revealed by microglial depletion in 5xFAD Mice

Nature Communications(2025)10.1038/s41467-025-64161-z

N/A

0DataRank · unranked

14 citations

Sepideh Kiani Shabestari, Savannah Barannikov, Kevin F. Bieniek, Mathew Blurton-Jones, Juan Pablo Palavicini +2 more

Human iPSC-derived APOE4/4 Alzheimer´s disease astrocytes exhibit a senescent and pro-inflammatory state that compromises neuronal support

Journal of Neuroinflammation(2025)10.1186/s12974-025-03607-z

N/A

0DataRank · unranked

5 citations

Elisabeth Sánchez‐Mejías, Laura Trujillo‐Estrada, Juan José Pérez-Moreno, Elba Lopez-Oliva, Tau En Lim +11 more

Amyloid precursor protein and C99 are subunits in human microglial Hv1 channels that enhance current and inflammatory mediator release

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2509903122

N/A

0DataRank · unranked

3 citations

Punyanuch Sophanpanichkul, Jean Paul Chadarevian, Yiwen Ding, Hui Dai, Mahasweta Nayak +4 more

CSF1R inhibitor-resistant model for CNS-wide microglia replacement strategies

Molecular Therapy(2025)10.1016/j.ymthe.2025.10.051

N/A

0DataRank · unranked

3 citations

Jasmine Nguyen, Lauren Le, L Angel Ayala, Alina L Chadarevian, Cuiwen Zhou +12 more

Microglia replacement by peripheral delivery of CSF1R inhibitor-resistant hematopoietic cells

Molecular Therapy(2025)10.1016/j.ymthe.2025.10.050

N/A

0DataRank · unranked

2 citations

Emily I. Church, Ryan N. Anderson, Carleigh A. O’Brien, Yixuan Zhu, Asif A. Dar +25 more

Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer’s disease

Science Translational Medicine(2025)10.1126/scitranslmed.adw7428

N/A

0DataRank · unranked

6 citations

Hanna Sabelström, Shan V. Andrews, Jean Paul Chadarevian, Marcus Y. Chin, David Tatarakis +46 more

Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease

Nature Communications(2020)10.1038/s41467-020-19227-5

N/A

0DataRank · unranked

356 citations

You Jung Kang, Jonathan Hasselmann, Amit Jairaman, Alexandra Sotelo, Morgan Coburn +17 more

Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials

Neurobiology of Disease(2020)10.1016/j.nbd.2020.104823

N/A

0DataRank · unranked

43 citations

Armine Hovakimyan, Indira S. Harahap-Carrillo, Hayk Davtyan, Tatevik Antonyan, Gor Chailyan +13 more

Cellular and molecular phenotypes of C9orf72 ALS/FTD patient derived iPSC-microglia mono-cultures

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.03.277459

N/A

0DataRank · unranked

6 citations

Eric Alsop, Jennifer Lévy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow +27 more

Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease

Molecular Neurodegeneration(2021)10.1186/s13024-021-00473-0

N/A

0DataRank · unranked

198 citations

Emma Danhash, Jonathan Hasselmann, Jean Paul Chadarevian, Sepideh Kiani Shabestari, Whitney England +6 more

Mathew Blurton-Jones

Indexed papers

Top data-sharing exemplar

Papers