Kira S. Makarova

Also affiliated with United States National Library of Medicine

Biochemistry, Genetics and Molecular BiologyEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.4Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

COG database update: focus on microbial diversity, model organisms, and widespread pathogens

Nucleic Acids Research(2020)10.1093/nar/gkaa1018

Top 3%

5.9DataRank

Top 3%1021 citations

Yuri I. Wolf, Kira S. Makarova, Roberto Vera Alvarez, David Landsman, Eugene V. Koonin +1 more

Papers

Driven by 58 papers — median percentile 92. Top paper: “COG database update: focus on microbial diversity, model organisms, and widespread pathogens”.

COG database update: focus on microbial diversity, model organisms, and widespread pathogens

Nucleic Acids Research(2020)10.1093/nar/gkaa1018

Top 3%

5.9DataRank

Top 3%1021 citations

Yuri I. Wolf, Kira S. Makarova, Roberto Vera Alvarez, David Landsman, Eugene V. Koonin +1 more

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

bioRxiv (Cold Spring Harbor Laboratory)(2016)10.1101/054742

N/A

1.8DataRank · unranked

46 citations

Jonathan S. Gootenberg, Silvana Konermann, Julia Joung, Ian M. Slaymaker, David B.T. Cox +11 more

COG database update 2024

Nucleic Acids Research(2024)10.1093/nar/gkae983

Top 13%

1.5DataRank

Top 13%128 citations

Roberto Vera Alvarez, Svetlana Karamycheva, Kira S. Makarova, Yuri I. Wolf, David Landsman +2 more

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Cell(2015)10.1016/j.cell.2015.09.038

N/A

1.3DataRank · unranked

4816 citations

Jonathan S. Gootenberg, Omar O. Abudayyeh, Ian M. Slaymaker, Kira S. Makarova, Patrick Essletzbichler +7 more

Diverse enzymatic activities mediate antiviral immunity in prokaryotes

Science(2020)10.1126/science.aba0372

N/A

0.978DataRank · unranked

676 citations

Han Altae-Tran, Francisca Böhning, Kira S. Makarova, Michael Segel, Jonathan L. Schmid-Burgk +5 more

Prokaryotic innate immunity through pattern recognition of conserved viral proteins

Science(2022)10.1126/science.abm4096

N/A

0.832DataRank · unranked

255 citations

Max E. Wilkinson, Jonathan Strecker, Kira S. Makarova, Rhiannon K. Macrae, Eugene V. Koonin +2 more

Cellular homologs of the double jelly-roll major capsid proteins clarify the origins of an ancient virus kingdom

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2120620119

N/A

0.590DataRank · unranked

50 citations

Kira S. Makarova, Eugene V. Koonin, Mart Krupovìč

Reprogrammable RNA-targeting CRISPR systems evolved from RNA toxin-antitoxins

Cell(2025)10.1016/j.cell.2025.01.034

N/A

0.546DataRank · unranked

37 citations

Han Altae-Tran, Soumya Kannan, Max E. Wilkinson, Samuel Chau-Duy-Tam Vo, Daniel Strebinger +9 more

Modularity and diversity of target selectors in Tn7 transposons

Molecular Cell(2023)10.1016/j.molcel.2023.05.013

N/A

0.533DataRank · unranked

34 citations

Makoto Saito, Sean Benler, Iris Peng, Yuri I. Wolf, Jonathan Strecker +8 more

Activation of bacterial programmed cell death by phage inhibitors of host immunity

Molecular Cell(2025)10.1016/j.molcel.2025.04.010

N/A

0.521DataRank · unranked

15 citations

Héloïse Carion, Kira S. Makarova, Eric Laderman, Thomas C. Todeschini, Pradeep Kumar +6 more

Structural Basis for a Dual Function ATP Grasp Ligase That Installs Single and Bicyclic ω-Ester Macrocycles in a New Multicore RiPP Natural Product

Journal of the American Chemical Society(2021)10.1021/jacs.1c02316

N/A

0.520DataRank · unranked

31 citations

Dalibor Košek, Hongbing Liu, Shannon I. Ohlemacher, Brittney Blackburne, A. N. NIKOL'SKAYA +7 more

Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail

Nature Communications(2024)10.1038/s41467-023-44630-z

N/A

0.479DataRank · unranked

10 citations

Leonid Minakhin, Ekaterina Goldobina, Brain Bae, Yue Hao, Sergei Borukhov +11 more

CoCoNuTs are a diverse subclass of Type IV restriction systems predicted to target RNA

eLife(2024)10.7554/elife.94800

N/A

0.385DataRank · unranked

12 citations

Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin, Ryan T. Bell

Anti-restriction functions of injected phage proteins revealed by peeling back layers of bacterial immunity

Nature Communications(2025)10.1038/s41467-025-63056-3

N/A

0.330DataRank · unranked

8 citations

Héloïse Carion, Kira S. Makarova, David Sanchez Godinez, Surabhi Haniyur, Lucy Volino +7 more

Long range segmentation of prokaryotic genomes by gene age and functionality

Nucleic Acids Research(2024)10.1093/nar/gkae745

N/A

0.292DataRank · unranked

6 citations

Ilya Schurov, Kira S. Makarova, M. I. Katsnelson, Eugene V. Koonin, Yuri I. Wolf

tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.10.468108

N/A

0.269DataRank · unranked

5 citations

Matvey Kolesnik, Leonid Minakhin, Natalia Morozova, Anna Shiriaeva, Alexandr Kirillov +8 more

Ecological determinants of altruism in prokaryote antivirus defense

Biology Direct(2025)10.1186/s13062-025-00699-8

N/A

0.165DataRank · unranked

2 citations

Kira S. Makarova, Yuri I. Wolf, Levi Waldron, Eugene V. Koonin, Nash D. Rochman +1 more

Uncovering the prevalence, key biogenesis enzymes, and biological significance of archaeal lipoproteins

Nature Communications(2025)10.1038/s41467-025-63625-6

N/A

0.104DataRank · unranked

1 citations

Kira S. Makarova, Andy A. Garcia, Rachel Xu, Friedhelm Pfeiffer, Paula V. Welander +2 more

Diversity, evolution, and classification of the RNA-guided nucleases TnpB and Cas12

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2308224120

N/A

0DataRank · unranked

72 citations

Sergey Shmakov, Kira S. Makarova, Yuri I. Wolf, Soumya Kannan, Feng Zhang +2 more

Widespread CRISPR-derived RNA regulatory elements in CRISPR-Cas systems

Nucleic Acids Research(2023)10.1093/nar/gkad495

N/A

0DataRank · unranked

28 citations

Zachary K. Barth, Kira S. Makarova, Yuri I. Wolf, Vyacheslav Brover, Joseph E. Peters +2 more

In Silico Approaches for Prediction of Anti-CRISPR Proteins

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168036

N/A

0DataRank · unranked

18 citations

Yuri I. Wolf, Eugene V. Koonin, Kira S. Makarova

Cellular differentiation into hyphae and spores in halophilic archaea

Nature Communications(2023)10.1038/s41467-023-37389-w

N/A

0DataRank · unranked

16 citations

Xiao‐Yang Zhi, Yao Zhang, Kira S. Makarova, Bing-Bing Liu, Guosong Zheng +32 more

Compensatory relationship between low-complexity regions and gene paralogy in the evolution of prokaryotes

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2300154120

N/A

0DataRank · unranked

14 citations

Yuri I. Wolf, Svetlana Karamycheva, Kira S. Makarova, Eugene V. Koonin, Erez Persi

Activation of programmed cell death and counter-defense functions of phage accessory genes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.06.535777

N/A

0DataRank · unranked

11 citations

Héloïse Carion, Kira S. Makarova, Eric Laderman, David Sanchez Godinez, Matthew C. Johnson +6 more

Widespread CRISPR repeat-like RNA regulatory elements in CRISPR-Cas systems

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.03.530964

N/A

0DataRank · unranked

5 citations

Zachary K. Barth, Kira S. Makarova, Yuri I. Wolf, Vyacheslav Brover, Joseph E. Peters +2 more

Diversity, Origin and Evolution of the ESCRT Systems

Research Square(2023)10.21203/rs.3.rs-2989530/v1

N/A

0DataRank · unranked

1 citations

Victor Tobiasson, Yuri I. Wolf, Zhongyi Lu, Yang Liu, Siyu Zhang +4 more

CoCoNuTs: A diverse subclass of Type IV restriction systems predicted to target RNA

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.31.551357

N/A

0DataRank · unranked

1 citations

Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin, Ryan T. Bell

Diversity, origin, and evolution of the ESCRT systems

mBio(2024)10.1128/mbio.00335-24

N/A

0DataRank · unranked

28 citations

Victor Tobiasson, Yuri I. Wolf, Zhongyi Lu, Yang Liu, Siyu Zhang +4 more

Computational analysis of genes with lethal knockout phenotype and prediction of essential genes in archaea

mBio(2024)10.1128/mbio.03092-23

N/A

0DataRank · unranked

6 citations

Changyi Zhang, Yuri I. Wolf, Svetlana Karamycheva, Rachel J. Whitaker, Eugene V. Koonin +1 more

Biochemical plasticity of the Escherichia coliCRISPR Cascade revealed by in vitro reconstitution of Cascade activities from purified Cas proteins

FEBS Journal(2024)10.1111/febs.17295

N/A

0DataRank · unranked

4 citations

Greg Brown, Kira S. Makarova, Eugene V. Koonin, Alexander F. Yakunin, Sofia Lemak

CoCoNuTs are a diverse subclass of Type IV restriction systems predicted to target RNA

eLife(2024)10.7554/elife.94800.3

N/A

0DataRank · unranked

2 citations

Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin, Ryan T. Bell

Diversity, Origin and Evolution of the ESCRT Systems

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.06.579148

N/A

0DataRank · unranked

1 citations

Victor Tobiasson, Yuri I. Wolf, Zhongyi Lu, Yang Liu, Siyu Zhang +4 more

CoCoNuTs: A diverse subclass of Type IV restriction systems predicted to target RNA

eLife(2024)10.7554/elife.94800.1

N/A

0DataRank · unranked

0 citations

Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin, Ryan T. Bell

Author response: CoCoNuTs: A diverse subclass of Type IV restriction systems predicted to target RNA

(2024)10.7554/elife.94800.2.sa3

N/A

0DataRank · unranked

0 citations

Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin, Ryan T. Bell

CoCoNuTs: A diverse subclass of Type IV restriction systems predicted to target RNA

eLife(2024)10.7554/elife.94800.2

N/A

0DataRank · unranked

0 citations

Harutyun Sahakyan, Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin, Ryan T. Bell

Long range segmentation of prokaryotic genomes by gene age and functionality

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.26.591304

N/A

0DataRank · unranked

0 citations

Ilya Schurov, Kira S. Makarova, M. I. Katsnelson, Eugene V. Koonin, Yuri I. Wolf

Ecological Determinants of Altruism in Prokaryote Antivirus Defense

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.05.622165

N/A

0DataRank · unranked

0 citations

Kira S. Makarova, Yuri I. Wolf, Levi Waldron, Eugene V. Koonin, Nash D. Rochman +1 more

An updated evolutionary classification of CRISPR–Cas systems including rare variants

Nature Microbiology(2025)10.1038/s41564-025-02180-8

N/A

0DataRank · unranked

60 citations

Sergey Shmakov, Yuri I. Wolf, Pascal Mutz, Han Altae-Tran, Chase L. Beisel +24 more

Jumbo phage killer immune system targets early infection of nucleus-forming phages

Cell(2025)10.1016/j.cell.2025.02.016

N/A

0DataRank · unranked

23 citations

Linlin Guan, Isabelle Becher, Kira S. Makarova, Xueli Cao, Surabhi Hareendranath +13 more

Spatial-temporal genome analysis and its application for the prediction of functional systems in bacteria and archaea

mBio(2025)10.1128/mbio.03127-25

N/A

0DataRank · unranked

2 citations

Yuri I. Wolf, Eugene V. Koonin, Kira S. Makarova, Svetlana Karamycheva

Ecological determinants of altruism in prokaryote antivirus defense

Research Square(2025)10.21203/rs.3.rs-7165116/v1

N/A

0DataRank · unranked

0 citations

Kira S. Makarova, Yuri I. Wolf, Levi Waldron, Eugene V. Koonin, Nash D. Rochman +1 more

Evolutionary and functional classification of the CARF domain superfamily, key sensors in prokaryotic antivirus defense

Nucleic Acids Research(2020)10.1093/nar/gkaa635

N/A

0DataRank · unranked

115 citations

Albertas Timinskas, Yuri I. Wolf, Ayal B. Gussow, Virginijus Šikšnys, Česlovas Venclovas +2 more

Machine-learning approach expands the repertoire of anti-CRISPR protein families

Nature Communications(2020)10.1038/s41467-020-17652-0

N/A

0DataRank · unranked

111 citations

Allyson E. Park, Adair L. Borges, Sergey Shmakov, Kira S. Makarova, Yuri I. Wolf +3 more

Vast diversity of anti-CRISPR proteins predicted with a machine-learning approach

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.23.916767

N/A

0DataRank · unranked

12 citations

Sergey Shmakov, Kira S. Makarova, Yuri I. Wolf, Joseph Bondy‐Denomy, Eugene V. Koonin +1 more

Expanding diversity of Asgard archaea and the elusive ancestry of eukaryotes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.19.343400

N/A

0DataRank · unranked

7 citations

Kira S. Makarova, Wen-Cong Huang, Yuri I. Wolf, Anastasia Nikolskaya, Xinxu Zhang +8 more

Expanded diversity of Asgard archaea and their relationships with eukaryotes

Nature(2021)10.1038/s41586-021-03494-3

N/A

0DataRank · unranked

346 citations

Kira S. Makarova, Wen-Cong Huang, Yuri I. Wolf, A. N. NIKOL'SKAYA, Xinxu Zhang +8 more

Evolution of Microbial Genomics: Conceptual Shifts over a Quarter Century

Trends in Microbiology(2021)10.1016/j.tim.2021.01.005

N/A

0DataRank · unranked

76 citations

Kira S. Makarova, Yuri I. Wolf, Eugene V. Koonin

Exposure to 1-Butanol Exemplifies the Response of the Thermoacidophilic Archaeon Sulfolobus acidocaldarius to Solvent Stress

Applied and Environmental Microbiology(2021)10.1128/aem.02988-20

N/A

0DataRank · unranked

19 citations

Laura Kuschmierz, Xiaoxiao Zhou, Andreas Albersmeier, Trong Khoa Pham, Tobias Busche +8 more

A Unique Gene Module in Thermococcales Archaea Centered on a Hypervariable Protein Containing Immunoglobulin Domains

Frontiers in Microbiology(2021)10.3389/fmicb.2021.721392

N/A

0DataRank · unranked

10 citations

Yuri I. Wolf, Svetlana Karamycheva, Eugene V. Koonin, Kira S. Makarova

tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector

Research Square(2021)10.21203/rs.3.rs-1068910/v1

N/A

0DataRank · unranked

3 citations

Ishita Jain, Matvey Kolesnik, Leonid Minakhin, Natalia Morozova, Anna Shiriaeva +8 more

Evolutionary plasticity and functional versatility of CRISPR systems

PLoS Biology(2022)10.1371/journal.pbio.3001481

N/A

0DataRank · unranked

91 citations

Kira S. Makarova, Eugene V. Koonin

RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease

Science(2022)10.1126/science.add7347

N/A

0DataRank · unranked

57 citations

Sae Okazaki, Cian Schmitt-Ulms, Kaiyi Jiang, Wenyuan Zhou, Junichiro Ishikawa +9 more

Structure of the IscB–ωRNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9

Nature Communications(2022)10.1038/s41467-022-34378-3

N/A

0DataRank · unranked

46 citations

Sae Okazaki, Soumya Kannan, Han Altae-Tran, F. Esra Demircioglu, Yukari Isayama +9 more

Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA

Nature(2022)10.1038/s41586-022-05324-6

N/A

0DataRank · unranked

42 citations

Kalli Kappel, Han Altae-Tran, Guilhem Faure, Max E. Wilkinson, Soumya Kannan +9 more

Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis

Biology Direct(2022)10.1186/s13062-022-00320-2

N/A

0DataRank · unranked

13 citations

Brittney Blackburne, Yuri I. Wolf, A. N. NIKOL'SKAYA, Svetlana Karamycheva, Marlene Espinoza‐Moraga +4 more

A family of novel immune systems targets early infection of nucleus-forming jumbo phages

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.17.508391

N/A

0DataRank · unranked

23 citations

Jingwen Guan, Surabhi Hareendranath, Emily Crawford, David A. Agard, Kira S. Makarova +3 more

RNA-triggered protein cleavage and cell death by the RNA-guided type III-E CRISPR-Cas nuclease-protease complex

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.17.504292

N/A

0DataRank · unranked

5 citations

Sae Okazaki, Cian Schmitt-Ulms, Kaiyi Jiang, Wenyuan Zhou, Junichiro Ishikawa +9 more

Tail-tape-fused virion and non-virion RNA polymerases of a thermophilic virus with an extremely long tail

The Medicine Forum(2022)10.1101/2022.12.01.518664

N/A

0DataRank · unranked

1 citations

Leonid Minakhin, Ekaterina Goldobina, Brain Bae, Yue Hao, Sergei Borukhov +10 more

Kira S. Makarova

Indexed papers

Top data-sharing exemplar

Papers