Roland A. Cooper

MedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda”.

Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa687

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225 citations

Melissa D. Conrad, Özkan Aydemir, Marvin Duvalsaint, Jennifer Legac, Elias Duarte +10 more

Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study

The Lancet Microbe(2021)10.1016/s2666-5247(21)00085-9

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77 citations

Thomas Katairo, Martin Okitwi, Oswald Byaruhanga, Stephen Orena, Victor Asua +13 more

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00173

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47 citations

Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey I. Gerasyuto, Sreekanth Kokkonda +39 more

Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice

Angewandte Chemie International Edition(2021)10.1002/anie.202015845

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40 citations

Hao Zhang, John D. Ginn, Annie Leung, Yi J. Liu, Mayako Michino +21 more

Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum

Malaria Journal(2021)10.1186/s12936-021-03823-x

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16 citations

Melissa D. Conrad, Stephen Tukwasibwe, Patrick K. Tumwebaze, Jennifer Legac, Roland A. Cooper +2 more

Decreased Susceptibility to Dihydrofolate Reductase Inhibitors Associated With Genetic Polymorphisms in Ugandan Plasmodium falciparum Isolates

The Journal of Infectious Diseases(2021)10.1093/infdis/jiab435

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12 citations

Patrick K. Tumwebaze, Oswald Byaruhanga, Thomas Katairo, Martin Okitwi, Stephen Orena +10 more

Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice

Angewandte Chemie(2021)10.1002/ange.202015845

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5 citations

Hao Zhang, John D. Ginn, Annie Leung, Yi J. Liu, Mayako Michino +21 more

Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.00771-21

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7 citations

Stephanie A. Rasmussen, Aarti Ramanathan, Patrick K. Tumwebaze, Oswald Byaruhanga, Thomas Katairo +14 more

Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda

Nature Communications(2022)10.1038/s41467-022-33873-x

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149 citations

Melissa D. Conrad, Martin Okitwi, Stephen Orena, Oswald Byaruhanga, Thomas Katairo +10 more

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Nature Communications(2022)10.1038/s41467-022-29688-5

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41 citations

Patrick A.M. Jansen, Catalina Barceló, Justin Munro, Julie M.J. Verhoef, Charisse Flerida A. Pasaje +40 more

Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01995

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32 citations

Fumiaki Yokokawa, Tom Kirrane, Anne-Catherine Mata, Richard S.P. Huang, Nicole Blaquière +39 more

Impact of Short-Term Storage on Ex Vivo Antimalarial Susceptibilities of Fresh Ugandan Plasmodium falciparum Isolates

Antimicrobial Agents and Chemotherapy(2022)10.1128/aac.01437-21

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1 citations

Stephen Orena, Thomas Katairo, Patrick K. Tumwebaze, Oswald Byaruhanga, Samuel L. Nsobya +5 more

Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda

New England Journal of Medicine(2023)10.1056/nejmoa2211803

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216 citations

Victor Asua, Shreeya Garg, David Giesbrecht, Karamoko Niaré, Sawyer Smith +12 more

Structure–Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01651

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14 citations

John D. Ginn, Wenhu Zhan, Annie Leung, Yi J. Liu, Akinori Toita +21 more

Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline

Microbiology Spectrum(2023)10.1128/spectrum.05236-22

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10 citations

Patrick K. Tumwebaze, Martin Okitwi, Stephen Orena, Oswald Byaruhanga, Thomas Katairo +16 more

Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.3c02046

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8 citations

Monica J. Bohmer, Jinhua Wang, Flore Nardella, Jaeson Calla, Mariana Laureano de Souza +14 more

Tambjamines as Fast-Acting Multistage Antimalarials

ACS Infectious Diseases(2024)10.1021/acsinfecdis.4c00659

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7 citations

Yuexin Li, Rozalia A. Dodean, Alison Roth, Diana Caridha, Michael S. Madejczyk +37 more

Ex vivo drug susceptibility and resistance mediating genetic polymorphisms of Plasmodium falciparum in Bobo-Dioulasso, Burkina Faso

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01534-23

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4 citations

Melissa D. Conrad, Zachari Kabré, Aminata Fofana, Rakiswendé Serge Yerbanga, Thomas Bazié +10 more

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission

Science Advances(2024)10.1126/sciadv.adq1383

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4 citations

Antima Gupta, Laura Drought, Avnish Patel, John Okombo, Mariëtte van der Watt +42 more

Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.00466-24

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1 citations

Stephen Orena, Martin Okitwi, Patrick K. Tumwebaze, Oswald Byaruhanga, Thomas Katairo +14 more

The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.01183-24

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1 citations

Douglas A. Shoue, Lisa A. Checkley, Stephen Orena, Frida G. Ceja, Yoweri Taremwa +14 more

Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019–2024

Nature Communications(2025)10.1038/s41467-025-62810-x

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15 citations

Stephen Orena, Patrick K. Tumwebaze, Thomas Katairo, Yoweri Taremwa, Oswald Byaruhanga +8 more

Plasmodium falciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity

Cell chemical biology(2025)10.1016/j.chembiol.2025.06.003

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9 citations

Tiantian Jiang, Lushun Wang, Monica J. Bohmer, Subhoja Chakraborty, John Okombo +32 more

Characterization of β-Carboline Derivatives Reveals a High Barrier to Resistance and Potent Activity against Ring-Stage and DHA-Induced Dormant Plasmodium falciparum

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00714

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2 citations

Joshua H. Butler, Lyric A. Wardlaw, Emilio F. Merino, Victoria Mendiola, Caitlin Cooper +12 more

Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019-2024

medRxiv(2025)10.1101/2024.12.31.24319821

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11 citations

Stephen Orena, Patrick K. Tumwebaze, Thomas Katairo, Yoweri Taremwa, Oswald Byaruhanga +7 more

Potent Acridone Antimalarial against All Three Life Stages of Plasmodium

Research Square(2025)10.21203/rs.3.rs-6858328/v1

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2 citations

Papireddy Kancharla, Rozalia A. Dodean, Yuexin Li, Xiaowei Zhang, Sean P. Kelly +40 more