Nobuyuki Takahashi

Ministry of Agriculture, Forestry and Fisheries

Also affiliated with National Institutes of Health, Aichi Medical University, Ministry of Agriculture Forestry and Fisheries, Tohoku University, National Cancer Institute, National Cancer Center Hospital East, Center for Cancer Research

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents”.

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-20-1026

N/A

2.9DataRank · unranked

111 citations

Ilya S. Senatorov, Astrid Zimmermann, Liton Kumar Saha, Yasuhisa Murai, Se Hyun Kim +8 more

Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer

JAMA Oncology(2023)10.1001/jamaoncol.2023.4025

N/A

1.1DataRank · unranked

48 citations

Zhonglin Hao, Liza C. Villaruz, Jun Zhang, Jimmy Ruiz, W. Jeffrey Petty +33 more

ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer

EMBO Molecular Medicine(2023)10.15252/emmm.202217313

N/A

0.944DataRank · unranked

28 citations

Yang Zhang, Rajaâ El Meskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai +21 more

Randomized phase II trial of topotecan plus M6620 (VX-970) versus topotecan alone in patients with relapsed small-cell neuroendocrine cancers including small cell lung cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.tps3653

N/A

0DataRank · unranked

0 citations

Rasa Vilimas, Samantha Nichols, Linda Sciuto, Santhana Webb, Seth M. Steinberg +3 more

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Cancer Cell(2021)10.1016/j.ccell.2021.02.014

N/A

0DataRank · unranked

178 citations

Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli +36 more

Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

Nature Communications(2021)10.1038/s41467-021-24164-y

N/A

0DataRank · unranked

164 citations

Moises J. Velez, Alberto Chiappori, Yoo Sun Kim, Jun S. Wei, Sivasish Sindiri +13 more

Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair–targeted therapies

Science Translational Medicine(2021)10.1126/scitranslmed.abc7488

N/A

0DataRank · unranked

73 citations

Nobuyuki Takahashi, Lőrinc Sándor Pongor, Vinodh N. Rajapakse, Manoj Tyagi, Xinyu Wen +20 more

Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect

Nature Cancer(2022)10.1038/s43018-022-00456-0

N/A

0DataRank · unranked

156 citations

Alexandros P. Drainas, Maya Baron, Debadrita Bhattacharya, Amira Barkal, Yasaman Ahrari +9 more

Heterogeneity of neuroendocrine transcriptional states in metastatic small cell lung cancers and patient-derived models

Nature Communications(2022)10.1038/s41467-022-29517-9

N/A

0DataRank · unranked

113 citations

Nobuyuki Takahashi, Parth Desai, Irena Manukyan, Christopher W. Schultz, Vinodh N. Rajapakse +14 more

Replication Stress Defines Distinct Molecular Subtypes Across Cancers

Cancer Research Communications(2022)10.1158/2767-9764.crc-22-0168

N/A

0DataRank · unranked

52 citations

Se Hyun Kim, Christopher W. Schultz, Vinodh N. Rajapakse, Yang Zhang, Christophe E. Redon +7 more

Translational research: A patient-centered approach to bridge the valley of death

Cancer Cell(2022)10.1016/j.ccell.2022.04.014

N/A

0DataRank · unranked

16 citations

Parth Desai, Nobuyuki Takahashi, Anish Thomas

PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM -Deficient Tumors and Potent Synergy With PARP Inhibitors

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-22-0217

N/A

0DataRank · unranked

11 citations

Shaun D. Fontaine, Morgan E. Diolaiti, Parth Desai, Rajesh Kumar, Nobuyuki Takahashi +9 more

Targeting genomic instability in extrapulmonary small cell neuroendocrine cancers: A phase II study with ATR inhibitor berzosertib and topotecan.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.8518

N/A

0DataRank · unranked

3 citations

Parth Desai, Linda Sciuto, Samantha Nichols, Seth M. Steinberg, Anish Thomas +1 more

Automated detection and segmentation of small cell lung cancer liver metastases on CT.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.e13555

N/A

0DataRank · unranked

0 citations

Parth Desai, Nobuyuki Takahashi, Nathan Lay, Peter L. Choyke, Anish Thomas +3 more

Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes

Cancer Discovery(2023)10.1158/2159-8290.cd-22-0796

N/A

0DataRank · unranked

118 citations

Christopher W. Schultz, Lorenzo Rinaldi, Darawalee Wangsa, Christophe E. Redon, Nobuyuki Takahashi +32 more

Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-0536

N/A

0DataRank · unranked

38 citations

Nobuyuki Takahashi, Cody J. Peer, Christophe E. Redon, Samantha Nichols, Rasa Vilimas +30 more

Dissecting small cell lung cancer subtypes with cell-free DNA fragmentomes.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.8592

N/A

0DataRank · unranked

1 citations

Zachary L. Skidmore, Bahar Alipanahi, Garrett T. Graham, Bryan Chesnick, Nobuyuki Takahashi +10 more

Microenvironment Shapes Small Cell Lung Cancer Neuroendocrine States and Presents Therapeutic Opportunities

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.09.579028

N/A

0DataRank · unranked

6 citations

Nobuyuki Takahashi, Rajesh Kumar, Samantha Nichols, Justin Malin, Allison L. Hunt +53 more

Metastatic organotropism in small cell lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.07.617066

N/A

0DataRank · unranked

4 citations

Anjali Dhall, Sarthak Sahoo, Christopher W. Schultz, Michelle A. Baird, Parth Desai +33 more

Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2503387122

N/A

0DataRank · unranked

4 citations

Sourav Saha, Anjali Dhall, Yang Zhang, Parth Desai, Lőrinc Sándor Pongor +31 more

Targeting DNA Repair to Drive Immune Responses: It's Time to Reconsider the Strategy for Clinical Translation

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-3841

N/A

0DataRank · unranked

15 citations

Ira Surolia, Anish Thomas, Nobuyuki Takahashi

Tumor-targeted top1 inhibitor delivery with optimized parp inhibition in advanced solid tumors: a phase i trial of gapped scheduling

Nature Communications(2025)10.1038/s41467-025-64509-5

N/A

0DataRank · unranked

3 citations

Nobuyuki Takahashi, Lenka Oplustil O’Connor, Christophe E. Redon, Chirayu Mohindroo, Linda Sciuto +8 more

Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers

CHEST Journal(2020)10.1016/j.chest.2020.04.068

N/A

0DataRank · unranked

35 citations

Idrees Mian, Camille Tlemsani, Lőrinc Sándor Pongor, Nobuyuki Takahashi, Kathleen Maignan +18 more

Dynamics of genomic and immune responses during primary immunotherapy resistance in mismatch repair–deficient tumors

Molecular Case Studies(2020)10.1101/mcs.a005678

N/A

0DataRank · unranked

5 citations

Vinodh N. Rajapakse, Lőrinc Sándor Pongor, Suresh Kumar, Camille Tlemsani, Rebecca Erwin-Cohen +8 more