Len A. Pennacchio

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

17.6Author DataRank

Indexed papers

7in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 7 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Expanded encyclopaedias of DNA elements in the human and mouse genomes

Nature(2020)10.1038/s41586-020-2493-4

Top 3%

6.4DataRank

Top 3%2615 citations

Federico Abascal, Reyes Acosta, Nicholas J. Addleman, Jessika Adrian, Veena Afzal +501 more

Papers

Driven by 51 papers — median percentile 74. Top paper: “A Common Allele on Chromosome 9 Associated with Coronary Heart Disease”.

A Common Allele on Chromosome 9 Associated with Coronary Heart Disease

Science(2007)10.1126/science.1142447

N/A

18.3DataRank · unranked

1584 citations

Alexander Pertsemlidis, Nihan Kavaslar, Alexandre Stewart, Robert Roberts, David R. Cox +8 more

Expanded encyclopaedias of DNA elements in the human and mouse genomes

Nature(2020)10.1038/s41586-020-2493-4

Top 3%

6.4DataRank

Top 3%2615 citations

Federico Abascal, Reyes Acosta, Nicholas J. Addleman, Jessika Adrian, Veena Afzal +501 more

An atlas of dynamic chromatin landscapes in mouse fetal development

Nature(2020)10.1038/s41586-020-2093-3

Top 5%

4.8DataRank

Top 5%441 citations

Iros Barozzi, Yuan Zhao, Yanxiao Zhang, Hui Huang, Ah Young Lee +38 more

The changing mouse embryo transcriptome at whole tissue and single-cell resolution

Nature(2020)10.1038/s41586-020-2536-x

Top 5%

4.6DataRank

Top 5%202 citations

Brian A. Williams, Diane Trout, Georgi K. Marinov, Henry Amrhein, Libera Berghella +11 more

Spatiotemporal DNA methylome dynamics of the developing mouse fetus

Nature(2020)10.1038/s41586-020-2119-x

N/A

3.6DataRank · unranked

195 citations

Manoj Hariharan, David U. Gorkin, Diane E. Dickel, Chongyuan Luo, Rosa G. Castanon +15 more

Topologically associating domain boundaries are required for normal genome function

Communications Biology(2023)10.1038/s42003-023-04819-w

N/A

2.5DataRank · unranked

156 citations

Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li +24 more

52 Genetic Loci Influencing Myocardial Mass

Journal of the American College of Cardiology(2016)10.1016/j.jacc.2016.07.729

N/A

2.4DataRank · unranked

135 citations

Jessica van Setten, Niek Verweij, Georg Vogler, Matthew T. Maurano, Xinchen Wang +172 more

VISTA Enhancer browser: an updated database of tissue-specific developmental enhancers

Nucleic Acids Research(2024)10.1093/nar/gkae940

Top 26%

0.766DataRank

Top 26%45 citations

Fotis A. Baltoumas, Guy Kelman, Joshua Boverhof, Yeongshnn Ong, Laura Cook +5 more

Increased Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals

bioRxiv (Cold Spring Harbor Laboratory)10.1101/2022.11.18.516017

N/A

0.615DataRank · unranked

11 citations

Valentina Snetkova, Grace Bower, Sandra Jacinto, Benjamin Clock, Atrin Dizehchi +9 more

Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues

Nature Structural & Molecular Biology(2024)10.1038/s41594-024-01431-2

Top 40%

0.482DataRank

Top 40%7 citations

Nathan R. Zemke, Ziyin Chen, Ivan Jurić, Rong Hu, Ramya Raviram +16 more

Range extender mediates long-distance enhancer activity

Nature(2025)10.1038/s41586-025-09221-6

N/A

0.477DataRank · unranked

23 citations

Ethan W. Hollingsworth, Sandra Jacinto, Joshua A. Alcantara, Ben Clock, Kaitlyn Cao +12 more

An Expanded Registry of Candidate cis-Regulatory Elements for Studying Transcriptional Regulation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.26.629296

Top 45%

0.416DataRank

Top 45%12 citations

Henry Pratt, Kaili Fan, Nishigandha Phalke, Jonathan Fisher, Shaimae I. Elhajjajy +37 more

A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders

Nature Communications(2024)10.1038/s41467-024-52463-7

N/A

0.389DataRank · unranked

9 citations

Lauren J. Ayers, Michael Kosicki, Wai‐Man Chan, Lydia Fozo, Brandon M. Pratt +22 more

SOX2-VSX2 Co-Occupancy Shapes Retinal Neurogenesis Through Dynamic Chromatin Regulation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.19.654956

N/A

0.104DataRank · unranked

1 citations

Kimiasadat Golestaneh, Emily F. Davis-Marcisak, Abdullah Khan, Marwa Daghsni, Keevon Flohr +5 more

Integrative analysis of the 3D genome and epigenome in mouse embryonic tissues

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.25.489471

Top 78%

0.104DataRank

Top 78%1 citations

Nathan R. Zemke, Ziyin Chen, Ivan Jurić, Rong Hu, Ramya Raviram +15 more

Characterization of Mammalian In Vivo Enhancers Using Mouse Transgenesis and CRISPR Genome Editing

Methods in molecular biology(2021)10.1007/978-1-0716-1847-9_11

N/A

0DataRank · unranked

44 citations

Stella Tran, Riana D. Hunter, Eman M. Meky, Kianna von Maydell, Anne Harrington +11 more

Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism

Human Genomics(2021)10.1186/s40246-021-00342-3

N/A

0DataRank · unranked

35 citations

Tristan J. Hayeck, Zhang Cheng, Sumantra Chatterjee, Brandon J. Mannion, Marta Byrska-Bishop +30 more

Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice

Genome Medicine(2021)10.1186/s13073-021-00884-0

N/A

0DataRank · unranked

25 citations

Anna Adhikari, Nycole A. Copping, Tyler W. Stradleigh, A. Ayanna Wade, Rinaldo Catta-Preta +19 more

HAND transcription factors cooperatively specify the aorta and pulmonary trunk

Developmental Biology(2021)10.1016/j.ydbio.2021.03.011

N/A

0DataRank · unranked

14 citations

Beth A. Firulli, Kevin P. Toolan, Marco Osterwalder, Len A. Pennacchio, Anthony B. Firulli +1 more

Topologically Associating Domain Boundaries are Commonly Required for Normal Genome Function

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.06.443037

N/A

0DataRank · unranked

10 citations

Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li +20 more

A noncoding single-nucleotide polymorphism at 8q24 drives IDH1 -mutant glioma formation

Science(2022)10.1126/science.abj2890

N/A

0DataRank · unranked

69 citations

Kristen Drucker, Thomas M. Kollmeyer, Ricky Tsai, Warren Winick‐Ng, Minggao Liang +54 more

Genome-wide fetalization of enhancer architecture in heart disease

Cell Reports(2022)10.1016/j.celrep.2022.111400

N/A

0DataRank · unranked

43 citations

Iros Barozzi, Michael Kosicki, Brandon J. Mannion, Matthew J. Blow, Yoko Fukuda-Yuzawa +21 more

Differential Etv2 threshold requirement for endothelial and erythropoietic development

Cell Reports(2022)10.1016/j.celrep.2022.110881

N/A

0DataRank · unranked

24 citations

Kelly Lammerts van Bueren, Diane E. Dickel, Ivana Zlatanova, Reuben Thomas, Carlos O. Lizama +8 more

Uncovering Hidden Enhancers Through Unbiased In Vivo Testing

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.29.493901

N/A

0DataRank · unranked

11 citations

Marco Osterwalder, Stella Tran, Ingrid Plajzer-Frick, Catherine S. Novak, Veena Afzal +20 more

A non-coding single nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation

medRxiv(2022)10.1101/2022.03.08.22272044

N/A

0DataRank · unranked

6 citations

Kristen Drucker, Thomas M. Kollmeyer, Ricky Tsai, Minggao Liang, Lingyan Jiang +38 more

Single cell, whole embryo phenotyping of pleiotropic disorders of mammalian development

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.03.500325

N/A

0DataRank · unranked

5 citations

Jana Henck, Chengxiang Qiu, Varun K. A. Sreenivasan, Saranya Balachandran, Rose Yinghan Behncke +28 more

Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.29.510167

N/A

0DataRank · unranked

0 citations

Beth A. Firulli, Ram Podicheti, Douglas B. Rusch, Brandon J. Mannion, Len A. Pennacchio +3 more

De Novo Mutation in an Enhancer of EBF3 in simplex autism

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.28.270751

N/A

0DataRank · unranked

2 citations

Tristan J. Hayeck, Brandon J. Mannion, Sumantra Chatterjee, Marta Byrska-Bishop, Rajeeva Musunuri +16 more

Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis

Nature Genetics(2023)10.1038/s41588-023-01424-9

N/A

0DataRank · unranked

37 citations

Silvio Alessandro Di Gioia, Bryn D. Webb, Wai‐Man Chan, Elke de Boer, Sarah J. Garnai +53 more

Single-cell, whole-embryo phenotyping of mammalian developmental disorders

Nature(2023)10.1038/s41586-023-06548-w

N/A

0DataRank · unranked

36 citations

Jana Henck, Chengxiang Qiu, Varun K. A. Sreenivasan, Saranya Balachandran, Oana V. Amarie +36 more

Single cell evaluation of endocardial Hand2 gene regulatory networks reveals HAND2-dependent pathways that impact cardiac morphogenesis

Development(2023)10.1242/dev.201341

N/A

0DataRank · unranked

14 citations

Beth A. Firulli, Ram Podicheti, Douglas B. Rusch, Brandon J. Mannion, Len A. Pennacchio +3 more

Rare variation in noncoding regions with evolutionary signatures contributes to autism spectrum disorder risk

medRxiv(2023)10.1101/2023.09.19.23295780

N/A

0DataRank · unranked

5 citations

Janet Song, Michael Kosicki, Connor Kenny, Samantha G. Beck, Lily Kelley +13 more

Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.28.546894

N/A

0DataRank · unranked

3 citations

Susan Lindtner, Athéna R. Ypsilanti, James D. Price, Armen Abnousi, Linda Su-Feher +12 more

Cell Type- and Tissue-specific Enhancers in Craniofacial Development

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.26.546603

N/A

0DataRank · unranked

2 citations

Kitt Paraiso, Maria Luisa Amaral, Michael Kosicki, Laura Cook, Fabrice Darbellay +26 more

Increased enhancer–promoter interactions during developmental enhancer activation in mammals

Nature Genetics(2024)10.1038/s41588-024-01681-2

N/A

0DataRank · unranked

82 citations

Valentina Snetkova, Grace Bower, Sandra Jacinto, Ben Clock, Atrin Dizehchi +9 more

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.22.393173

N/A

0DataRank · unranked

3 citations

Brandon J. Mannion, Matteo Zoia, Raquel Rouco, Virginie Tissières, Cailyn H. Spurrell +22 more

Rare variation in non-coding regions with evolutionary signatures contributes to autism spectrum disorder risk

Cell Genomics(2024)10.1016/j.xgen.2024.100609

N/A

0DataRank · unranked

32 citations

Janet Song, Michael Kosicki, Connor Kenny, Samantha G. Beck, Lily Kelley +13 more

Dynamic enhancer landscapes in human craniofacial development

Nature Communications(2024)10.1038/s41467-024-46396-4

N/A

0DataRank · unranked

27 citations

Kitt Paraiso, Maria Luisa Amaral, Michael Kosicki, Laura Cook, Fabrice Darbellay +26 more

Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer

Journal of Clinical Investigation(2024)10.1172/jci183353

N/A

0DataRank · unranked

10 citations

Seong Won Kim, David Saul, Meraj Neyazi, Manuel Schmid, Hiroko Wakimoto +27 more

Presynaptic Homeostasis Opposes Disease Progression in Mouse Models of ALS-Like Degeneration: Evidence for Homeostatic Neuroprotection

Neuron(2020)10.1016/j.neuron.2020.04.009

N/A

0DataRank · unranked

61 citations

Anna G. Hauswirth, Barbara Celona, Richard D. Fetter, Giulia Zunino, Evgeny Z. Kvon +5 more

Nr2f1 enhancers have distinct functions in controlling Nr2f1 expression during cortical development

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2402368121

N/A

0DataRank · unranked

2 citations

Athéna R. Ypsilanti, Eirene Markenscoff-Papadimitriou, Diane E. Dickel, Stephan Sanders, Shan Dong +4 more

Conserved Cis -Acting Range Extender Element Mediates Extreme Long-Range Enhancer Activity in Mammals

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.26.595809

N/A

0DataRank · unranked

21 citations

Ethan W. Hollingsworth, Sandra Jacinto, Ben Clock, Kaitlyn Cao, Mandy Liu +11 more

ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function

Circulation Research(2020)10.1161/circresaha.120.317145

N/A

0DataRank · unranked

64 citations

Ravi Mandla, Hongmei Ruan, Catherine Jung, Tanvi Sinha, Nicole R. Stone +10 more

Mutagenesis Sensitivity Mapping of Human Enhancers In Vivo

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.06.611737

N/A

0DataRank · unranked

3 citations

Boyang Zhang, Anusri Pampari, Jennifer A. Akiyama, Ingrid Playzer-Frick, Catherine S. Novak +12 more

Supervised enhancer prediction with epigenetic pattern recognition and targeted validation

Nature Methods(2020)10.1038/s41592-020-0907-8

N/A

0DataRank · unranked

120 citations

Mengting Gu, Emrah Gumusgoz, Landon L. Chan, Koon‐Kiu Yan, Joel Rozowsky +20 more

Uncovering hidden enhancers through unbiased in vivo testing

Nature Communications(2025)10.1038/s41467-025-62497-0

N/A

0DataRank · unranked

6 citations

Stella Tran, Ingrid Plajzer-Frick, Catherine S. Novak, Veena Afzal, Jennifer A. Akiyama +21 more

SOX2-driven enhancer landscape defines the transcriptional architecture of retinogenesis

Development(2025)10.1242/dev.204986

N/A

0DataRank · unranked

1 citations

Kimiasadat Golestaneh, Emily Jane Davis, Abdullah Khan, Brendan Nicholson, Marwa Daghsni +6 more

Ultraconserved enhancer function does not require perfect sequence conservation

Nature Genetics(2021)10.1038/s41588-021-00812-3

N/A

0DataRank · unranked

93 citations

Athéna R. Ypsilanti, Jennifer A. Akiyama, Brandon J. Mannion, Ingrid Plajzer-Frick, Catherine S. Novak +16 more

Comprehensive In Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants

Cell(2020)10.1016/j.cell.2020.02.031

N/A

0DataRank · unranked

194 citations

Yiwen Zhu, Guy Kelman, Catherine S. Novak, Ingrid Plajzer-Frick, Momoe Kato +22 more

Transcriptional network orchestrating regional patterning of cortical progenitors

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2024795118

N/A

0DataRank · unranked

56 citations

Kartik Pattabiraman, Rinaldo Catta-Preta, Olga Golonzhka, Susan Lindtner, Ke Tang +15 more

Reactivation of a developmentally silenced embryonic globin gene

Nature Communications(2021)10.1038/s41467-021-24402-3

N/A

0DataRank · unranked

51 citations

Duantida Songdej, Damien J. Downes, Robert A. Beagrie, Siyu Liu, Megan Buckley +21 more

Len A. Pennacchio

Indexed papers

Top data-sharing exemplar

Papers