Scott A. Armstrong

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 38 papers. Top paper: “The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia”.

The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

Nature(2023)10.1038/s41586-023-05812-3

N/A

5.2DataRank · unranked

480 citations

Ibrahim Aldoss, John F. Dipersio, Branko Cuglievan, Richard M. Stone, Martha Arellano +19 more

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

eLife(2023)10.7554/elife.80854

N/A

0.715DataRank · unranked

24 citations

Yadira M. Soto‐Feliciano, John P. Morris, Chun‐Hao Huang, Richard P. Koche, Yu-Jui Ho +12 more

Inherited blood cancer predisposition through altered transcription elongation

Cell(2024)10.1016/j.cell.2023.12.016

N/A

0.694DataRank · unranked

25 citations

Liam D. Cato, Uma P. Arora, Erik L. Bao, Samuel C. Bryant, Nicholas Williams +8 more

NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AML

Cell Reports(2024)10.1016/j.celrep.2024.114901

N/A

0.422DataRank · unranked

12 citations

Cynthia Martucci, Jill A. Henrich, Dana S. Neel, Sanisha Mahendra-Rajah, Hannah Rice +6 more

The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79

UNC Libraries(2020)10.17615/8dsb-2z68

N/A

0DataRank · unranked

4 citations

Aniruddha J. Deshpande, Or Gozani, Benjamin A. García, Scott A. Armstrong, Brian D. Strahl +6 more

Leukemia cell of origin influences apoptotic priming and sensitivity to LSD1 inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.11.089060

N/A

0DataRank · unranked

7 citations

S. Haihua Chu, Aaron D. Goldberg, Salma Parvin, Richard P. Koche, Jacob L. Glass +22 more

A JAK/STAT-Mediated Inflammatory Signaling Cascade Drives Oncogenesis In AF10-Rearranged AML

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.31.273631

N/A

0DataRank · unranked

3 citations

Anagha Deshpande, Karina Barbosa, Maria Kleppe, Xue Li, Narayana Yeddula +15 more

YBX1 mediates translation of oncogenic transcripts to control cell competition in AML

Leukemia(2021)10.1038/s41375-021-01393-0

N/A

0DataRank · unranked

65 citations

Tina M. Schnoeder, Yijun Xiong, Ashok Kumar Jayavelu, Nomusa Mashamba, Nuria Tubío Santamaría +17 more

High-resolution characterization of gene function using single-cell CRISPR tiling screen

Nature Communications(2021)10.1038/s41467-021-24324-0

N/A

0DataRank · unranked

45 citations

Anthony Chan, Kazuya Miyashita, Christopher D. Delaney, Xi Wang, Hongzhi Li +21 more

HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-3538

N/A

0DataRank · unranked

30 citations

Shannon Coy, Jia‐Ren Lin, Jessica L. Andersen, Joanna Przybył, Emanuele Mazzola +7 more

Histone PTM Crosstalk Stimulates Dot1 Methyltransferase Activity

Trends in Biochemical Sciences(2021)10.1016/j.tibs.2021.04.001

N/A

0DataRank · unranked

9 citations

Florian Perner, Scott A. Armstrong, Jevon Cutler

Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA

JCI Insight(2021)10.1172/jci.insight.149382

N/A

0DataRank · unranked

4 citations

Adam C. Searleman, Shugaku Takeda, Scott A. Armstrong, Christopher Y. Park, Emily H. Cheng +2 more

High-resolution characterization of gene function using single-cell CRISPR tiling screen

Research Square(2021)10.21203/rs.3.rs-135816/v1

N/A

0DataRank · unranked

1 citations

Anthony Chan, Kazuya Miyashita, Christopher D. Delaney, Xi Wang, Hongzhi Li +21 more

Mutant NPM1 Directly Regulates Oncogenic Transcription in Acute Myeloid Leukemia

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0366

N/A

0DataRank · unranked

131 citations

Elena Haarer, Reina Takeda, Eric Wong, Charlie Hatton, Christian Marinaccio +9 more

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

Cell stem cell(2022)10.1016/j.stem.2022.04.007

N/A

0DataRank · unranked

87 citations

Dominik Vonficht, Alexandra Schnell, Hannah J. Uckelmann, Alina Bollhagen, Mohamed A. A. Mahmoud +37 more

A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0416

N/A

0DataRank · unranked

84 citations

Francisco J. Sánchez‐Rivera, Florian Perner, Douglas Barrows, Edward R. Kastenhuber, Yu-Jui Ho +17 more

MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape

Molecular Cell(2022)10.1016/j.molcel.2022.02.013

N/A

0DataRank · unranked

70 citations

Laura Godfrey, James P. Healy, Yoolim A. Choi, Kai Yan, Charles Hatton +6 more

MOZ and Menin–MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor

Cancer Discovery(2022)10.1158/2159-8290.cd-21-0646

N/A

0DataRank · unranked

43 citations

Morgan R. Benson, Michael A. Loycano, Justin A. Anderson, Jessica L. Andersen, Madeleine L. Taddei +7 more

SETD2 Haploinsufficiency Enhances Germinal Center–Associated AICDA Somatic Hypermutation to Drive B-cell Lymphomagenesis

Cancer Discovery(2022)10.1158/2159-8290.cd-21-1514

N/A

0DataRank · unranked

30 citations

Matt Teater, Ceyda Durmaz, Cem Meydan, Alexandra G. Chivu, Amy Chadburn +14 more

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.07.495174

N/A

0DataRank · unranked

0 citations

Changyu Zhu, John P. Morris, Chun‐Hao Huang, Richard P. Koche, Yu-Jui Ho +12 more

MEN1 mutations mediate clinical resistance to menin inhibition

Nature(2023)10.1038/s41586-023-05755-9

N/A

0DataRank · unranked

251 citations

Eytan M. Stein, Daniela V. Wenge, Sukrit Singh, Jeonghyeon Kim, Athina Apazidis +24 more

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability

Molecular Cell(2023)10.1016/j.molcel.2023.06.028

N/A

0DataRank · unranked

73 citations

Jacob D. Aguirre, Yen-Der Li, Jared Brown, Vivian Focht, Lukas Kater +30 more

KDM6A epigenetically regulates subtype plasticity in small cell lung cancer

Nature Cell Biology(2023)10.1038/s41556-023-01210-z

N/A

0DataRank · unranked

69 citations

Yixiang Li, Matthew A. Booker, Yingtian Xie, Sarah Naomi Olsen, Radhika A. Patel +19 more

Data from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

(2023)10.1158/1078-0432.c.6530451

N/A

0DataRank · unranked

0 citations

Shannon Coy, Jia‐Ren Lin, Jessica L. Andersen, Joanna Przybył, Emanuele Mazzola +7 more

Data from HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor

(2023)10.1158/1078-0432.c.6530451.v1

N/A

0DataRank · unranked

0 citations

Shannon Coy, Jia‐Ren Lin, Jessica L. Andersen, Joanna Przybył, Emanuele Mazzola +7 more

A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2405905121

N/A

0DataRank · unranked

14 citations

Daniel Sullivan, Sarah Naomi Olsen, Heather A. Kang, Samuel D. Whedon, Jonathan B. Baell +4 more

CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2 - and TET2 -mutant Cells

Cancer Discovery(2024)10.1158/2159-8290.cd-23-1092

N/A

0DataRank · unranked

11 citations

Shoron Mowla, Meaghan Boileau, Anthony R. Martinez Benitez, Junya Sango, Maya Bagish +20 more

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer(2025)10.1002/ijc.35332

N/A

0DataRank · unranked

19 citations

Jayant Y. Gadrey, Scott A. Armstrong, Michael W.M. Kühn, Florian Perner

KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98 -Rearranged Acute Myeloid Leukemia

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1772

N/A

0DataRank · unranked

16 citations

Emily Heikamp, Ilaria Iacobucci, Masayuki Umeda, Bright Arthur, Vibhor Mishra +37 more

An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis

Blood(2025)10.1182/blood.2024028033

N/A

0DataRank · unranked

9 citations

Peter G. Kim, Thuy T. P. Nguyen, Meaghan Boileau, Marie McConkey, Aidan Miller +9 more

p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma

EMBO Reports(2025)10.1038/s44319-025-00552-z

N/A

0DataRank · unranked

7 citations

Brandon Regalado, Sydney R. Schweber, Charlie Hatton, Daniela V. Wenge, Yanhe Wen +8 more

Menin inhibition for the treatment of acute leukemia

Seminars in Hematology(2025)10.1053/j.seminhematol.2025.08.001

N/A

0DataRank · unranked

7 citations

Scott A. Armstrong, Daniela V. Wenge

Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102192

N/A

0DataRank · unranked

9 citations

Bryn Anderson, Charlie Hatton, Zhengtao Chu, Christopher E. Simpkins, Yanhe Wen +8 more

Therapeutic targeting of preleukemia cells in a mouse model of NPM1 mutant acute myeloid leukemia

Science(2020)10.1126/science.aax5863

N/A

0DataRank · unranked

275 citations

Stephanie M. Kim, Eric Wong, Charlie Hatton, Hugh Giovinazzo, Jayant Y. Gadrey +9 more

The Prolonged Half-Life of the p53 Missense Variant R248Q Promotes Accumulation and Heterotetramer Formation with Wild-Type p53 to Exert the Dominant-Negative Effect

Cancer Research(2025)10.1158/0008-5472.can-24-1136

N/A

0DataRank · unranked

4 citations

Roman R. Schimmer, Nils K. Konrad, Flavian Thelen, Jonas Fullin, Ebru Topçu +17 more

Chromatin Complexes Maintain Self-Renewal of Myeloid Progenitors in AML: Opportunities for Therapeutic Intervention

Stem Cell Reports(2020)10.1016/j.stemcr.2020.05.013

N/A

0DataRank · unranked

21 citations

Scott A. Armstrong, Hannah J. Uckelmann

Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development

iScience(2020)10.1016/j.isci.2020.100941

N/A

0DataRank · unranked

15 citations

Jonathan Chabon, Chloe Matovina, Janna Minehart, Bo-Ruei Chen, Jian Zhang +12 more

Oncogenic Gene-Expression Programs in Leiomyosarcoma and Characterization of Conventional, Inflammatory, and Uterogenic Subtypes

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-20-0197

N/A

0DataRank · unranked

35 citations

Changyu Fan, Chandrajit P. Raut, George D. Demetri, Scott A. Armstrong, Ewa Sicińska +2 more