Gordon M. Stott

Also affiliated with Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc. (United States)

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 16 papers. Top paper: “Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties”.

Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00916

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1.7DataRank · unranked

63 citations

Daniel J. Urban, Bryan T. Mott, Xin Hu, Shyh‐Ming Yang, Gloria A. Benavides +40 more

Allosteric p97 Inhibitors Can Overcome Resistance to ATP‐Competitive p97 Inhibitors for Potential Anticancer Therapy

ChemMedChem(2020)10.1002/cmdc.201900722

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0DataRank · unranked

32 citations

Shan Li, Taiping Gan, Gordon M. Stott, Andrew Flint, Tsui‐Fen Chou +1 more

Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00019

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0DataRank · unranked

29 citations

Karavadhi Surendra, Rajan Pragani, Li Liu, Yuhong Fang, Weihe Zhang +28 more

Optimization of ether and aniline based inhibitors of lactate dehydrogenase

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127974

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0DataRank · unranked

5 citations

Kwangho Kim, Somnath Jana, Ian M. Romaine, Ganesha Rai, Bryan T. Mott +18 more

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2211297120

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0DataRank · unranked

38 citations

Somenath Chowdhury, Kenneth M. Meyers, Jianhua Tian, Jiqing Sai, Mayme Van Meveren +15 more

Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c00195

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0DataRank · unranked

32 citations

Kenneth M. Meyers, Qiangqiang Wei, Jonathan J. Mills, Jianhua Tian, Joseph Alvarado +11 more

Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-22-0167

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0DataRank · unranked

10 citations

Christina Mazcko, Timothy M. Fan, David M. Vail, Brian K. Flesner, Jeffrey N. Bryan +14 more

Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.16.504162

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0DataRank · unranked

2 citations

Vicky Li, Spencer D. Shelton, Jiwoong Kim, Gordon M. Stott, Leonard Μ. Neckers +5 more

Mitochondrial-Encoded Complex I Impairment Induces a Targetable Dependency on Aerobic Fermentation in Hürthle Cell Carcinoma of the Thyroid

Cancer Discovery(2023)10.1158/2159-8290.cd-22-0982

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0DataRank · unranked

18 citations

Vicky Li, Spencer D. Shelton, Jiwoong Kim, Gordon M. Stott, Leonard Μ. Neckers +5 more

Optimization of 1,2,4-Triazole-Based p97 Inhibitors for the Treatment of Cancer

ACS Medicinal Chemistry Letters(2023)10.1021/acsmedchemlett.3c00163

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0DataRank · unranked

12 citations

Celeste Alverez, Alexander Chatterley, Marina Kovaliov, Evan J. Carder, Michael J. Houghton +16 more

Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01529

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0DataRank · unranked

9 citations

Jonathan J. Mills, Jianhua Tian, Changho Han, Kenneth M. Meyers, Jiqing Sai +12 more

Supplemental Methods from Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

(2023)10.1158/0008-5472.22422704

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0DataRank · unranked

0 citations

Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa +23 more

Supplemental Methods from Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

Figshare(2023)10.1158/0008-5472.22422704.v1

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0DataRank · unranked

0 citations

Anna E. Gibson, Sameer H. Issaq, Nobu Oshima, Joshua T. Baumgart, Leah D. Edessa +23 more

Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01188

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0DataRank · unranked

17 citations

James M. Salovich, Martin Aichinger, KyuOk Jeon, Nagarathanam Veerasamy, John Sensintaffar +22 more

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy

Cell Reports(2020)10.1016/j.celrep.2020.01.039

N/A

0DataRank · unranked

125 citations

Ryo Ishida, Shun Kishimoto, Kristin Beebe, Jeffrey Brender, Kazutoshi Yamamoto +36 more

Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2408889121

N/A

0DataRank · unranked

12 citations

Brianna N. Smith, Jing Wang, Kevin B. Teuscher, Brian C. Grieb, Gregory C. Howard +12 more