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Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.16.504162Source: DataRank Database

Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)OA: greenTopics (28)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Vicky Li ORCID,Spencer D. Shelton ORCID,Jiwoong Kim ORCID,Gordon M. Stott ORCID,Leonard Μ. Neckers

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W4292122117

National Institutes of Health

Grant: 3P30CA142543-12S1

Multidimensional single-cell approach probing HIV-1 integration association with non-AIDS defining cancers (Biospecimens/Biocohort)

National Institutes of Health

Grant: 5T32GM007062-44

Mechanisms of Drug Action and Disposition

green

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/08/17/2022.08.16.504162.full.pdf

repositoryhttps://doi.org/10.1101/2022.08.16.504162

https://doi.org/10.1158/2159-8290.cd-22-0982

https://pubmed.ncbi.nlm.nih.gov/37262072

Fields of Study

Mitochondrial Function and PathologyCancer, Hypoxia, and MetabolismATP Synthase and ATPases Research0301 basic medicine03 medical and health sciences

Keywords

Warburg effectGlycolysisMitophagyMitochondrionBiologyCellular respirationCellRespirationProgrammed cell deathCell biologyBiochemistryLactate dehydrogenaseMetabolismEnzymeCancer researchApoptosisFermentationCarcinomaHumansAdenoma, OxyphilicThyroid NeoplasmsAdenocarcinomaDNA, Mitochondrial

Sustainable Development Goals

SDG 0: Good health and well-being