Igor B. Roninson

Also affiliated with Drug Discovery Laboratory (Norway), Senex Biotechnology (United States)

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 9 papers. Top paper: “The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs”.

The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs

Cells(2021)10.3390/cells10010144

N/A

0DataRank · unranked

36 citations

Chang‐Uk Lim, Martina S.J. McDermott, Chuck Hennes, Kingsavanh P. Philavong, Tiffanie Aiken +4 more

A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.1c01951

N/A

0DataRank · unranked

38 citations

Chen Cheng, Jing Li, Lili Wang, Alexander A. Chumanevich, Donald C. Porter +6 more

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins

Nucleic Acids Research(2023)10.1093/nar/gkad538

N/A

0DataRank · unranked

68 citations

Jing Li, Li Zhang, Lili Wang, Chen Cheng, Hao Ji +20 more

CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.08.552491

N/A

0DataRank · unranked

2 citations

Thomas A. Hilimire, Yueying Liu, Lili Wang, Jiaxin Liang, Balázs Győrffy +19 more

Anoikis resistance and metastasis of ovarian cancer can be overcome by CDK8/19 Mediator kinase inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.04.569970

N/A

0DataRank · unranked

1 citations

Resha Rajkarnikar, Emily Faith Page, Asha Kumari, Liz Quintero-Macías, Felipe Massicano +12 more

Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2414501121

N/A

0DataRank · unranked

7 citations

Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov +9 more

Mediator kinase inhibition reverses castration resistance of advanced prostate cancer

Journal of Clinical Investigation(2024)10.1172/jci176709

N/A

0DataRank · unranked

22 citations

Thomas A. Hilimire, Yueying Liu, Lili Wang, Jiaxin Liang, Balázs Győrffy +21 more

Host-derived Interleukin 1α induces an immunosuppressive tumor microenvironment via regulating monocyte-to-macrophage differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.03.592354

N/A

0DataRank · unranked

2 citations

Gourab Sen Gupta, Grace Atkinson, Katie L. Kathrein, Alissa Richmond Armstrong, Michael Gower +12 more

Inhibition of CDK8 rescues impaired ischemic fracture healing

Research Square(2025)10.21203/rs.3.rs-6458483/v1

N/A

0DataRank · unranked

1 citations

Michelle J. Song, Easton C. Farrell, Alexander J. Knights, Karen Kessell, Alexis Donneys +8 more