Douglas F. Covey

NeuroscienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 38 papers. Top paper: “Fatty acid synthesis configures the plasma membrane for inflammation in diabetes”.

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes

Nature(2016)10.1038/nature20117

N/A

0.869DataRank · unranked

327 citations

Haowei Song, Li Yin, Michael G. Rizzo, Rohini Sidhu, Douglas F. Covey +3 more

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Journal of Neuroinflammation(2020)10.1186/s12974-020-01869-3

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0DataRank · unranked

121 citations

Michael Lewis, James Doherty, Yang Shi, Anil G. Cashikar, Anna Amelianchik +9 more

Site-specific effects of neurosteroids on GABAA receptor activation and desensitization

eLife(2020)10.7554/elife.55331

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0DataRank · unranked

60 citations

Wayland W.L. Cheng, John Bracamontes, Zi-Wei Chen, Lei Wang, Allison L. Germann +8 more

The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models

Autophagy(2020)10.1080/15548627.2020.1731270

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0DataRank · unranked

49 citations

Sanae Takaseki, Takeshi Yoshitomi, Douglas F. Covey, Charles F. Zorumski, Yukitoshi Izumi +1 more

The T-type calcium channel isoform Cav3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile

British Journal of Anaesthesia(2020)10.1016/j.bja.2020.07.022

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0DataRank · unranked

22 citations

Simon Feseha, Francesca M. Manzella, Damon Wallace, Davis Wilkey, Timothy Corrigan +8 more

A neuroactive steroid with a therapeutically interesting constellation of actions at GABAA and NMDA receptors

Neuropharmacology(2020)10.1016/j.neuropharm.2020.108358

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0DataRank · unranked

14 citations

Isaac Mordukhovich, Daniel M. Chen, Mariangela Chisari, Hong-Jin Shu, Peter Lambert +5 more

Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis

Biochemistry(2020)10.1021/acs.biochem.0c00013

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0DataRank · unranked

13 citations

Andrew G. Wagner, Robert T. Stagnitta, Zihan Xu, John L. Pezzullo, José‐Luis Giner +5 more

Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABAA currents, but are not neurotoxic to the developing rat brain

British Journal of Anaesthesia(2020)10.1016/j.bja.2020.01.013

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0DataRank · unranked

40 citations

Srdjan M. Joksimovic, Nidia Quillinan, Kathiresan Krishnan, Douglas F. Covey, Slobodan M. Todorovic +2 more

Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels

Cells(2020)10.3390/cells9122674

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0DataRank · unranked

8 citations

Srdjan M. Joksimovic, Kathiresan Krishnan, Douglas F. Covey, Slobodan M. Todorovic, Vesna Jevtovic‐Todorovic +1 more

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.14.906966

N/A

0DataRank · unranked

2 citations

Michael Lewis, James Doherty, Yang Shi, Patrick M. Sullivan, Mingxing Qian +6 more

Site-specific effects of neurosteroids on GABA A receptor activation and desensitization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.27.063404

N/A

0DataRank · unranked

1 citations

Wayland W.L. Cheng, John Bracamontes, Zi-Wei Chen, Lei Wang, Allison L. Germann +8 more

4β-hydroxycholesterol is a pro-lipogenic factor that promotes SREBP1c expression and activity through Liver X-receptor

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.20.256487

N/A

0DataRank · unranked

0 citations

Peter‐James H. Zushin, Charles A. Berdan, Robert J. van Eijkeren, Xuntian Jiang, Mingxing Qian +7 more

Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells

Scientific Reports(2021)10.1038/s41598-021-87876-7

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0DataRank · unranked

39 citations

Christian W. Heegaard, Stephan Werner, Gerd Schneider, Kathiresan Krishnan, Douglas F. Covey +2 more

4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor

Journal of Lipid Research(2021)10.1016/j.jlr.2021.100051

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0DataRank · unranked

29 citations

Peter-James H. Zushin, Charles A. Berdan, Robert J. van Eijkeren, Xuntian Jiang, Mingxing Qian +7 more

Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling

Nature Communications(2021)10.1038/s41467-021-27475-2

N/A

0DataRank · unranked

32 citations

R. Schwáb, Kamel El Omari, B. Bishop, Ellen J. Iverson, Tomas Malinauskas +7 more

Differential effects of the novel neurosteroid hypnotic (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile on electroencephalogram activity in male and female rats

British Journal of Anaesthesia(2021)10.1016/j.bja.2021.03.029

N/A

0DataRank · unranked

22 citations

Dayalan Sampath, Kathiresan Krishnan, Douglas F. Covey, Vesna Jevtović‐Todorović, Yogendra H. Raol +2 more

Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the “Irreversibility Rule” for Protein Autoprocessing Inhibition

Biochemistry(2021)10.1021/acs.biochem.1c00697

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0DataRank · unranked

6 citations

Robert T. Stagnitta, Zihan Xu, John L. Pezzullo, Nabin Kandel, José‐Luis Giner +4 more

Polyunsaturated fatty acids inhibit a pentameric ligand‐gated ion channel through one of two specific binding sites

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.00280

N/A

0DataRank · unranked

0 citations

Noah M. Dietzen, John T. Petroff, Douglas F. Covey, Mark J. Arcario, Wayland W.L. Cheng

Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.08.463634

N/A

0DataRank · unranked

0 citations

Mark J. Arcario, Lawrence J. Chen, John T. Petroff, Kathiresan Krishnan, Grace Brannigan +3 more

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

Cell Metabolism(2020)10.1016/j.cmet.2020.03.010

N/A

0DataRank · unranked

204 citations

Bishuang Cai, Xiaoming Yang, Oluwatoni O. Sonubi, Ze Zheng, Rajasekhar Ramakrishnan +14 more

Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain

Science Advances(2022)10.1126/sciadv.abm5563

N/A

0DataRank · unranked

61 citations

Rachel E. Woolley, T. Bertie Ansell, Eamon F.X. Byrne, Sara Frigui, Giovanni Luchetti +10 more

Sex-specific hypnotic effects of the neuroactive steroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid

British Journal of Anaesthesia(2022)10.1016/j.bja.2022.09.025

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0DataRank · unranked

8 citations

Omar H. Cabrera, Davis Wilkey, Brier Fine-Raquet, Jelena Klawitter, Kathiresan Krishnan +4 more

Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH

Frontiers in Pharmacology(2022)10.3389/fphar.2022.850658

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0DataRank · unranked

4 citations

Francesca M. Manzella, Stefan Maksimovic, Kathiresan Krishnan, Douglas F. Covey, Vesna Jevtović‐Todorović +2 more

General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action

International Journal of Molecular Sciences(2022)10.3390/ijms23031889

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0DataRank · unranked

7 citations

Nemanja Useinovic, Nidia Quillinan, Douglas F. Covey, Slobodan M. Todorovic, Vesna Jevtović‐Todorović +1 more

Discovery of the first tight‐binding reversible antagonists of Hedgehog protein autoprocessing

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3075

N/A

0DataRank · unranked

0 citations

Robert T. Stagnitta, Zihan Xu, John L. Pezzullo, Nabin Kandel, José‐Luis Giner +4 more

Neurosteroid enantiomers as potentially novel neurotherapeutics

Neuroscience & Biobehavioral Reviews(2023)10.1016/j.neubiorev.2023.105191

N/A

0DataRank · unranked

31 citations

Alex S. Evers, Yukitoshi Izumi, Jamie Maguire, Steven Mennerick, Charles F. Zorumski +1 more

Synthetic routes to trifluoromethylphenyl diazirine photolabeling reagents containing an alkyne substituent (TPDYNE) for chemical biology applications

RSC Advances(2023)10.1039/d3ra07260f

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0DataRank · unranked

6 citations

Yuanjian Xu, Douglas F. Covey, Mingxing Qian

Neonatal exposure to a neuroactive steroid alters low-frequency oscillations in the subiculum

Experimental Biology and Medicine(2023)10.1177/15353702231177009

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0DataRank · unranked

4 citations

Francesca M. Manzella, Srdjan M. Joksimovic, Robert M. Dietz, James E. Orfila, Dayalan Sampath +8 more

GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.23.540554

N/A

0DataRank · unranked

7 citations

Simone Harrison, Sun‐Hee Hwang, Zi-Wei Chen, Masha Karelina, Ishan Deshpande +14 more

GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway

Nature Structural & Molecular Biology(2024)10.1038/s41594-024-01223-8

N/A

0DataRank · unranked

37 citations

Simone Harrison, Sun‐Hee Hwang, Zi-Wei Chen, Masha Karelina, Ishan Deshpande +14 more

Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100738

N/A

0DataRank · unranked

7 citations

Hogan P. Bryce-Rogers, Nienke J Dekker, Anna Wiehl Bønke, Nicolo' Camporese, Mingxing Qian +4 more

Inhibitory Actions of Potentiating Neuroactive Steroids in the Human α1β3γ2L γ-Aminobutyric Acid Type A Receptor

Molecular Pharmacology(2024)10.1124/molpharm.124.000960

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0DataRank · unranked

4 citations

Allison L. Germann, Douglas F. Covey, Alex S. Evers, Joe Henry Steinbach, Gustav Akk +1 more

Direct measurements of neurosteroid binding to specific sites on GABAA receptors

British Journal of Pharmacology(2024)10.1111/bph.16490

N/A

0DataRank · unranked

5 citations

Hiroki Tateiwa, Mingxing Qian, Yuanjian Xu, Fatima Amtashar, Ziwei Chen +7 more

Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent Neurosteroids

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00571

N/A

0DataRank · unranked

2 citations

Peter Reinholdt, Rasmus Schnoor-Madsen, Line Lauritsen, J P Bader, M. Qian +9 more

Comparison of Behavioral Effects of GABAergic Low- and High-Efficacy Neuroactive Steroids in the Zebrafish Larvae Assay

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.3c00836

N/A

0DataRank · unranked

1 citations

Yuanjian Xu, Douglas F. Covey, Alex S. Evers, Gustav Akk, Allison L. Germann

Phosphorylation of CRYAB induces a condensatopathy to worsen post–myocardial infarction left ventricular remodeling

Journal of Clinical Investigation(2025)10.1172/jci163730

N/A

0DataRank · unranked

4 citations

David R. Rawnsley, Xiucui Ma, Walter Navid, Chen Zhao, Xumin Guan +19 more

Target validation uncouples TSPO from 19-Atriol-mediated inhibition of steroidogenesis and reveals true enzymatic targets

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.25.678677

N/A

0DataRank · unranked

0 citations

Prasanthi P. Koganti, Mingxing Qian, Anthony G. K. Garcia, Patrick O’Day, Richard J. Auchus +3 more

Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

Science(2022)10.1126/science.abg6621

N/A

0DataRank · unranked

133 citations

Y. Rose Citron, Lei Wang, Laura Tribouillard, Claire S. Goul, Robin Stipp +15 more