Safal Shrestha

Also affiliated with University of California San Diego

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases”.

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

eLife(2023)10.7554/elife.87958

N/A

0.450DataRank · unranked

13 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs

Science Advances(2024)10.1126/sciadv.adl1258

N/A

0.396DataRank · unranked

13 citations

Dominic P. Byrne, Safal Shrestha, Tyler M. Lakey, Kyung‐Soon Lee, Sophia M. Lauer +9 more

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

Nature Communications(2021)10.1038/s41467-021-21191-7

N/A

0.312DataRank · unranked

7 citations

Christopher R. Horne, Safal Shrestha, J.R. Keown, Lung‐Yu Liang, Samuel N. Young +8 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.29.534689

N/A

0.292DataRank · unranked

6 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms

eLife(2025)10.7554/elife.92536.4

N/A

0.269DataRank · unranked

5 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Redox regulation and dynamic control of brain-selective kinases BRSK1/2 in the AMPK family through cysteine-based mechanisms

eLife(2024)10.7554/elife.92536

N/A

0.165DataRank · unranked

2 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

ChemRxiv(2020)10.26434/chemrxiv.12616178

N/A

0.165DataRank · unranked

2 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily

Science Signaling(2020)10.1126/scisignal.aax6313

N/A

0DataRank · unranked

24 citations

Samiksha Katiyar, Carlos E. Sanz-Rodríguez, Nolan R. Kemppinen, Hyun W. Kim, Renuka Kadirvelraj +12 more

Protein kinase inhibitor selectivity “hinges” on evolution

Structure(2022)10.1016/j.str.2022.11.004

N/A

0DataRank · unranked

7 citations

George Bendzunas, Natarajan Kannan, Safal Shrestha

Computational tools and resources for pseudokinase research

Methods in enzymology on CD-ROM/Methods in enzymology(2022)10.1016/bs.mie.2022.03.040

N/A

0DataRank · unranked

10 citations

Safal Shrestha, Krzysztof Kochut, Patrick A. Eyers, Natarajan Kannan, Brady O’Boyle

Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2

Biochemical Journal(2022)10.1042/bcj20220474

N/A

0DataRank · unranked

5 citations

Safal Shrestha, Leonard A. Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E. Eyers +3 more

Evolutionary and cellular analysis of the dark pseudokinase PSKH2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.10.507278

N/A

0DataRank · unranked

0 citations

Safal Shrestha, Leonard A. Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E. Eyers +3 more

A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01174

N/A

0DataRank · unranked

30 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more

Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4

Structure(2020)10.1016/j.str.2020.07.016

N/A

0DataRank · unranked

39 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

(2023)10.7554/elife.87958.2

N/A

0DataRank · unranked

2 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.05.561145

N/A

0DataRank · unranked

2 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

(2023)10.7554/elife.87958.1

N/A

0DataRank · unranked

1 citations

Grace Watterson, Dominic P. Byrne, Brady O’Boyle, Safal Shrestha, Nathan Gravel +10 more

Reviewer #1 (Public Review): Mechanistic and evolutionary insights into isoform-specific ‘supercharging’ in DCLK family kinases

(2023)10.7554/elife.87958.2.sa1

N/A

0DataRank · unranked

0 citations

W. Kevin Grace, Byrne Dominic P., O’Boyle Brady, Safal Shrestha, Gravel Nathan +10 more

Cataloguing the dead: breathing new life into pseudokinase research

FEBS Journal(2020)10.1111/febs.15246

N/A

0DataRank · unranked

60 citations

Dominic P. Byrne, John A. Harris, Natarajan Kannan, Patrick A. Eyers, Safal Shrestha

Multi-omics reveals new links between Fructosamine-3-Kinase (FN3K) and core metabolic pathways

npj Systems Biology and Applications(2024)10.1038/s41540-024-00390-0

N/A

0DataRank · unranked

6 citations

Rahil Taujale, Samiksha Katiyar, Natarajan Kannan, Safal Shrestha

Illuminating the functions of the understudied Fructosamine-3-kinase (FN3K) using a multi-omics approach reveals new links to lipid, carbon, and co-factor metabolic pathways

Research Square(2024)10.21203/rs.3.rs-3934957/v1

N/A

0DataRank · unranked

3 citations

Safal Shrestha, Rahil Taujale, Samiksha Katiyar, Natarajan Kannan

Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

eLife(2024)10.7554/elife.92536.1

N/A

0DataRank · unranked

1 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Author response: Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

(2024)10.7554/elife.92536.3.sa3

N/A

0DataRank · unranked

0 citations

Dominic P. Byrne, Safal Shrestha, Leonard A. Daly, Sally O. Oswald, Samiksha Katiyar +6 more

Nucleotide binding, evolutionary insights and interaction partners of the pseudokinase Unc-51-like kinase 4

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.18.159293

N/A

0DataRank · unranked

2 citations

Deep Chatterjee, Sebastian Mathea, Safal Shrestha, Jonathan St‐Germain, Manipa Saha +5 more

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity

Science Signaling(2020)10.1126/scisignal.aax2713

N/A

0DataRank · unranked

113 citations

Safal Shrestha, Martin Galler, Min Cao, Leonard A. Daly, A. Campbell +5 more

A Chemical Probe for Dark Kinase STK17B Derives its Potency and High Selectivity Through a Unique P-loop Conformation

ChemRxiv(2020)10.26434/chemrxiv.12616178.v1

N/A

0DataRank · unranked

1 citations

A. Chaikuad, Carrow I. Wells, Safal Shrestha, William J. Zuercher, Julie E. Pickett +10 more