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Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs

Science Advances(2024)10.1126/sciadv.adl1258Source: DataRank Database

Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs is a research paper published in Science Advances (2024). On theSindex it has a DataRank of 0. It has been cited 11 times.

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Open Access11 citations

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Enrichment:Funding (17 grants)OA: goldTopics (16)IDs (PubMed, PMC)Annotations (2)

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Authors (14)

Dominic P. Byrne ORCID,Safal Shrestha ORCID,Tyler M. Lakey,Kyung‐Soon Lee ORCID,Sophia M. Lauer ORCID

Live enrichment

PubMed:38381834 PMC:PMC10881042

NIDDK NIH HHS

Grant: R01 DK119192

NIDDK NIH HHS

Grant: R01 DK141129

NIH HHS

Grant: S10 OD021502

Biotechnology and Biological Sciences Research Council

Grant: BB/T018127/1

An ion-mobility mass spectrometry platform for single-cell proteomics and sensitive discrimination of isomeric biomolecules

Biotechnology and Biological Sciences Research Council

Grant: BB/R000182/1

Understanding complexity of post-translation modifications by enhancing UK capability for top-down proteomics

NIDDK NIH HHS

Grant: F32 DK121415

NIDDK NIH HHS

Grant: T32 DK007247

NIGMS NIH HHS

Grant: R35 GM139656

Biotechnology and Biological Sciences Research Council

Grant: BB/S018514/1

Analysis of the dynamic sulfotyrosine proteome.

NCI NIH HHS

Grant: R01 CA279997

NIGMS NIH HHS

Grant: R01 GM129090

National Institutes of Health

Grant: 1S10OD021502-01A1

A NanoLC-Orbitrap Tribrid Instrument for Comprehensive Proteomics Analyses

National Institutes of Health

Grant: 5R01CA279997-02

Targeting Oncogenic PKA signaling mechanisms

National Institutes of Health

Grant: 3F32DK121415-03S1

Molecular mechanisms of PKA mutations underlying Cushing's syndrome

National Institutes of Health

Grant: 1ZIADK013039-04

Molecular modeling of soluble proteins

National Institutes of Health

Grant: 5R01DK119192-04

Defective PKA Signaling in Cushing's Syndrome

National Institutes of Health

Grant: 5R01GM129090-04

Defining Pathway-Specific Kinase Signaling Modules with Proteomics

goldLicense: http://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adl1258

Europe_PMChttps://europepmc.org/articles/PMC10881042

Europe_PMChttps://europepmc.org/articles/PMC10881042?pdf=render

https://doi.org/10.1126/sciadv.adl1258

https://pubmed.ncbi.nlm.nih.gov/38381834

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

HumansCushing SyndromeSignal TransductionCatalytic DomainA Kinase Anchor ProteinsBias

Keywords

BiasCatalytic DomainHumansA Kinase Anchor ProteinsBiomedicine and Life SciencesCushing SyndromeSignal Transduction