Þorkell Andrésson

Also affiliated with National Institutes of Health, Protein Express (United States), Frederick National Laboratory for Cancer Research, National Cancer Institute, National Cancer Institute, Center for Cancer Research, Leidos Biomedical Research Inc. (United States), National Cancer Research Institute

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 66 papers. Top paper: “A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells”.

A small protein encoded by a putative lncRNA regulates apoptosis and tumorigenicity in human colorectal cancer cells

eLife(2020)10.7554/elife.53734

N/A

3.0DataRank · unranked

110 citations

Lőrinc Sándor Pongor, Wei Tang, Sudipto Das, Bruna Rodrigues Muys, Matthew F. Jones +24 more

Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress

EMBO Reports(2021)10.15252/embr.202052122

N/A

1.1DataRank · unranked

34 citations

Navdeep Malik, Young‐Im Kim, Yunlong He, Mangmang Li, Wendy Dubois +13 more

A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma

Clinical Cancer Research(2022)10.1158/1078-0432.ccr-22-2168

N/A

0.815DataRank · unranked

22 citations

R. Taylor Sundby, Mary Frances Wedekind, Fernanda I. Arnaldez, Jaydira Del Rivero, Lori Wiener +27 more

Transfer RNA acetylation regulates in vivo mammalian stress signaling

Science Advances(2025)10.1126/sciadv.ads2923

N/A

0.330DataRank · unranked

8 citations

Roxane Khoogar, Shereen Howpay Manage, Judey T. DaRos, McKenna C. Crawford, Joe Georgeson +30 more

Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors

Metabolomics(2024)10.1007/s11306-024-02185-0

N/A

0.279DataRank · unranked

5 citations

Marina Amaral Alves, Þorkell Andrésson, Amanda L. Bayless, Kent Bloodsworth, John A. Bowden +60 more

Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family

Familial Cancer(2021)10.1007/s10689-021-00267-9

N/A

0.241DataRank · unranked

4 citations

Mai Xu, Michael R. Sargen, Hyunbum Jang, Mingzhen Zhang, Tongwu Zhang +24 more

PhpCNF-Y transcription factor infiltrates heterochromatin to generate cryptic intron-containing transcripts crucial for small RNA production

Nature Communications(2025)10.1038/s41467-024-55736-3

N/A

0.226DataRank · unranked

3 citations

H. Diego Folco, Patroula Nathanailidou, Anupa T Anil, Drisya Vijayakumari, Shweta Jain +6 more

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.16.452547

N/A

0.165DataRank · unranked

2 citations

Venkata R. Sabbasani, Vasty Osei-Amponsa, Christine N. Evans, Julianna C. King, Sergey G. Tarasov +15 more

TNIK Is a Therapeutic Target in Lung Squamous Cell Carcinoma and Regulates FAK Activation through Merlin

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0797

N/A

0DataRank · unranked

57 citations

Elvira An, Katherine M. Nyswaner, Ryan C. Bensen, Daniel A. Ritt, Suzanne I. Specht +15 more

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

Nature Communications(2021)10.1038/s41467-021-27176-w

N/A

0DataRank · unranked

57 citations

Berkley E. Gryder, Benjamin D. Sunkel, Þorkell Andrésson, Marco Wachtel, Sudipto Das +16 more

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

Nature Communications(2021)10.1038/s41467-021-27570-4

N/A

0DataRank · unranked

35 citations

Venkata R. Sabbasani, Vasty Osei-Amponsa, Christine N. Evans, Julianna C. King, Sergey G. Tarasov +16 more

SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100491

N/A

0DataRank · unranked

16 citations

Jing Lin, Diwash Acharya, Thiruvaimozhi Abimannan, Srideshikan Sargur Madabushi, Kimberly D. Klarmann +10 more

Novel MAPK/AKT-impairing germline NRAS variant identified in a melanoma-prone family

medRxiv(2021)10.1101/2021.04.20.21254596

N/A

0DataRank · unranked

1 citations

Mai Xu, Michael R. Sargen, Hyunbum Jang, Mingzhen Zhang, Tongwu Zhang +24 more

Protonation-Dependent Sequencing of 5-Formylcytidine in RNA

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.23.469744

N/A

0DataRank · unranked

1 citations

Supuni Thalalla Gamage, Diamond A. Gallimore, Robert Kopajtich, Christine N. Evans, Samantha R. Nance +7 more

Male infertility‐associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery

EMBO Reports(2022)10.15252/embr.202152775

N/A

0DataRank · unranked

38 citations

Jian Sun, Christine Insinna, Quanlong Lü, Ziqiu Wang, Kunio Nagashima +7 more

Protonation-Dependent Sequencing of 5-Formylcytidine in RNA

Biochemistry(2022)10.1021/acs.biochem.1c00761

N/A

0DataRank · unranked

21 citations

Supuni Thalalla Gamage, Diamond Gallimore, Robert Kopajtich, Christine N. Evans, Samantha Nance +7 more

Protonation‐Dependent Sequencing of 5‐Formylcytidine in RNA

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5310

N/A

0DataRank · unranked

1 citations

Supuni Thalalla Gamage, Diamond A. Gallimore, Robert Kopajtich, Christine N. Evans, Samantha R. Nance +7 more

3’UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.29.486281

N/A

0DataRank · unranked

0 citations

Nida Asif, Srikanta Basu, Aniruddha Das, Mei Yang, Baktiar Karim +10 more

HLA class I signal peptide polymorphism determines the level of CD94/NKG2–HLA-E-mediated regulation of effector cell responses

Nature Immunology(2023)10.1038/s41590-023-01523-z

N/A

0DataRank · unranked

73 citations

Arman Bashirova, Mathias Viard, Lee Garner, Max Quastel, Maya Beiersdorfer +14 more

Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming

Nature Communications(2023)10.1038/s41467-023-40738-4

N/A

0DataRank · unranked

52 citations

Ronald J. Holewinski, Christopher McGinity, Ciro Leonardo Pierri, Nunziata Maio, Jonathan M. Weiss +7 more

A virus-induced circular RNA maintains latent infection of Kaposi’s sarcoma herpesvirus

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2212864120

N/A

0DataRank · unranked

44 citations

Daniel K. Oh, Sarah E. Dremel, Guruswamy Mahesh, Vishal N. Koparde, Gerard Duncan +3 more

Investigating the NRAS 5′ UTR as a target for small molecules

Cell chemical biology(2023)10.1016/j.chembiol.2023.05.004

N/A

0DataRank · unranked

41 citations

Zachary R. Torrey, David Calabrese, Michael T. Banco, Kamyar Yazdani, Liang Xiao +8 more

Covalent Inhibition by a Natural Product-Inspired Latent Electrophile

Journal of the American Chemical Society(2023)10.1021/jacs.3c00598

N/A

0DataRank · unranked

31 citations

Jennifer M. Ritchie, Ye‐Jin Jung, Ronald J. Holewinski, Hong‐Rae Kim, Ravichandra Tagirasa +6 more

SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck

Cell Reports(2023)10.1016/j.celrep.2023.112823

N/A

0DataRank · unranked

26 citations

Benjamin Bernard, Samantha Sevilla, Sohyoung Kim, Mohd Saleem Dar, Daniel Tsai +33 more

hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50

Molecular Cell(2023)10.1016/j.molcel.2023.11.035

N/A

0DataRank · unranked

16 citations

Monika Chandravanshi, Xiuxiu Lu, Valentin Magidson, Sudipto Das, Þorkell Andrésson +10 more

SARS-CoV-2 papain-like protease plays multiple roles in regulating cellular proteins in the endoplasmic reticulum

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105346

N/A

0DataRank · unranked

8 citations

Jennifer Mariano, R. Su, Christopher E. Smith, Sudipto Das, Catherine Gill +5 more

Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2305037120

N/A

0DataRank · unranked

8 citations

Klára Kirsch, Hobin Lee, Paola Oliva, Jong Il Ahn, H. Ravishankar +8 more

A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment

Scientific Reports(2023)10.1038/s41598-023-41690-5

N/A

0DataRank · unranked

3 citations

Lu Huang, Blair Kreh, Xiuxia Liu, Liliya Tyutyunyk‐Massey, Masanori Kawakami +14 more

Pyruvate Dehydrogenase Operates as an Intramolecular Nitroxyl Generator During Macrophage Metabolic Reprogramming

Research Square(2023)10.21203/rs.3.rs-2238134/v1

N/A

0DataRank · unranked

1 citations

Ronald J. Holewinski, Christopher McGinity, Ciro Leonardo Pierri, Nunziata Maio, Vincenzo Tragni +6 more

IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

Cancer Cell(2024)10.1016/j.ccell.2024.05.026

N/A

0DataRank · unranked

35 citations

Michele Ceribelli, Sebastian Scheich, Kristina Rinaldi, Da Wei Huang, Papiya Chakraborty +16 more

Genome-scale exon perturbation screens uncover exons critical for cell fitness

Molecular Cell(2024)10.1016/j.molcel.2024.05.024

N/A

0DataRank · unranked

24 citations

Arun Prasath Damodaran, Bandana Kumari, Ethan Dickson, Kun Xing, Tyler A. On +13 more

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation

Nature Communications(2024)10.1038/s41467-024-50925-6

N/A

0DataRank · unranked

20 citations

Meili Ge, Chengyu Liu, Ronald J. Holewinski, Þorkell Andrésson, Zu‐Xi Yu +5 more

Specialized replication of heterochromatin domains ensures self-templated chromatin assembly and epigenetic inheritance

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2315596121

N/A

0DataRank · unranked

18 citations

Jothy Dhakshnamoorthy, Hua Xiao, Martin Zofall, Sahana Holla, Maura O’Neill +4 more

A patient-derived cell model for malignant transformation in IDH-mutant glioma

Acta Neuropathologica Communications(2024)10.1186/s40478-024-01860-6

N/A

0DataRank · unranked

9 citations

Zach Sergi, Guangyang Yu, Kazutoshi Yamamoto, Martha Quezado, Zied Abdullaev +17 more

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins

Nature Communications(2024)10.1038/s41467-024-46644-7

N/A

0DataRank · unranked

7 citations

Monika Chandravanshi, Venkata R. Sabbasani, Snehal Gaikwad, V. Keith Hughitt, Nana Gyabaah-Kessie +18 more

Discovery of a Tunable Heterocyclic Electrophile 4-Chloro-pyrazolopyridine That Defines a Unique Subset of Ligandable Cysteines

ACS Chemical Biology(2024)10.1021/acschembio.4c00025

N/A

0DataRank · unranked

7 citations

David P. Byun, Kalyani Thakur, Jennifer M. Ritchie, Yixin Xie, Ronald J. Holewinski +9 more

Targeted sulfur(VI) fluoride exchange-mediated covalent modification of a tyrosine residue in the catalytic pocket of tyrosyl-DNA phosphodiesterase 1

Communications Chemistry(2024)10.1038/s42004-024-01298-w

N/A

0DataRank · unranked

7 citations

I Barakat, G.T. Lountos, Wenjie Wang, Keli Agama, Md Rasel Al Mahmud +5 more

Metabolism‐focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer

Molecular Carcinogenesis(2024)10.1002/mc.23705

N/A

0DataRank · unranked

6 citations

Renzo Cavero, Yue Liu, Haojian Li, Xia Xu, Þorkell Andrésson +9 more

Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma

NAR Cancer(2024)10.1093/narcan/zcae004

N/A

0DataRank · unranked

11 citations

Mariana D. Mandler, Judith C. Lunger, Dalen Chan, Siddhardha S. Maligireddy, Alexandra C Schmiechen +10 more

Loss of NAT10 disrupts enhancer organization via p300 mislocalization and suppresses transcription of genes necessary for metastasis progression

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.24.577116

N/A

0DataRank · unranked

3 citations

Ngoc‐Han Ha, Tinghu Qiu, Ronald J. Holewinski, Khiem C. Lam, Amélie Lopès +9 more

Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.19.585805

N/A

0DataRank · unranked

1 citations

Elizabeth Brooks, Madison S. Taylor, Liping Yang, Ronald J. Holewinski, Thomas J. Meyer +7 more

Large-scale multi-omic analysis identifies noncoding somatic driver mutations and nominates ZFP36L2 as a driver gene for pancreatic ductal adenocarcinoma

medRxiv(2024)10.1101/2024.09.22.24314165

N/A

0DataRank · unranked

1 citations

Aidan O’Brien, Minal Patel, Daina Eiser, Michael Mobaraki, Irene Collins +18 more

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.08.588544

N/A

0DataRank · unranked

0 citations

Anthony O. Omole, Ye‐Jin Jung, Wioletta Rut, Ronald J. Holewinski, Kiall F. Suazo +6 more

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins

UNC Libraries(2024)10.17615/cr0z-4y62

N/A

0DataRank · unranked

0 citations

Charles D. Schwieters, Rolf E. Swenson, V. Keith Hughitt, Raj Chari, Venkata R. Sabbasani +18 more

Allelic effects on KLHL17 expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33

medRxiv(2024)10.1101/2024.09.16.24313748

N/A

0DataRank · unranked

0 citations

Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Aidan O’Brien +12 more

Immunophenotype of CAR T cells and apheresis products predicts response in CD22 CAR T cell trial for B cell acute lymphoblastic leukemia

Molecular Therapy(2025)10.1016/j.ymthe.2025.03.019

N/A

0DataRank · unranked

14 citations

Lipei Shao, Yihua Cai, Kyu Lee Han, Michaela Prochazkova, Michael Gertz +11 more

Transient APC/C inactivation by mTOR boosts glycolysis during cell cycle entry

Nature(2025)10.1038/s41586-025-09328-w

N/A

0DataRank · unranked

10 citations

Derek L. Bolhuis, Hualong Yan, Sudipto Das, Xia Xu, Christina C. Abbate +8 more

Identification of molecular determinants of gene-specific bursting patterns by high-throughput imaging screens

Molecular Cell(2025)10.1016/j.molcel.2025.01.022

N/A

0DataRank · unranked

11 citations

Ronald J. Holewinski, Þorkell Andrésson, Daniel R. Larson, Tom Misteli, Varun Sood

A 3D Self-Assembly Platform Integrating Decellularized Matrix Recapitulates In Vivo Tumor Phenotypes and Heterogeneity

Cancer Research(2025)10.1158/0008-5472.can-24-1954

N/A

0DataRank · unranked

6 citations

Elizabeth Brooks, Madison S. Taylor, Ireolu K. Orenuga, Liping Yang, Ronald J. Holewinski +8 more

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

Nature Communications(2025)10.1038/s41467-025-56336-5

N/A

0DataRank · unranked

5 citations

Anthony O. Omole, Ye‐Jin Jung, Wioletta Rut, Ronald J. Holewinski, Kiall F. Suazo +6 more

NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA

Molecular Cell(2025)10.1016/j.molcel.2025.11.010

N/A

0DataRank · unranked

5 citations

Ngoc‐Han Ha, Tinghu Qiu, Ronald J. Holewinski, Khiem C. Lam, Amélie Lopès +7 more

Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates ZFP36L2 as a driver gene for pancreatic ductal adenocarcinoma

Gut(2025)10.1136/gutjnl-2025-335152

N/A

0DataRank · unranked

2 citations

Aidan O’Brien, Minal Patel, Daina Eiser, Michael Mobaraki, Irene Collins +19 more

Expression of IMPACT Curtails Metabolic Plasticity and Augments NK Cell Killing to Abrogate Metastatic Growth

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1055

N/A

0DataRank · unranked

2 citations

Abir K. Panda, Rodrigo Xavier das Neves, Zeribe C. Nwosu, Ke Xu, Elke van Beek +59 more

Potent β-lactam-based tyrosyl-DNA phosphodiesterase 1 inhibitors identified by a virtual screen

Scientific Reports(2025)10.1038/s41598-025-12503-8

N/A

0DataRank · unranked

1 citations

Wenjie Wang, Kiall F. Suazo, Md Rasel Al Mahmud, Keli Agama, G.T. Lountos +4 more

RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.25.648738

N/A

0DataRank · unranked

0 citations

Jeongjin Kim, Shreya Kordale, Arun Prasath Damodaran, Bandana Kumari, Sandra Vidak +7 more

Cell cycle dependent methylation of Dam1 contributes to kinetochore integrity and faithful chromosome segregation

PLoS Genetics(2025)10.1371/journal.pgen.1011760

N/A

0DataRank · unranked

0 citations

Wei-Chun Au, John S. Choy, Pedro G. Castiñeira, Afsa Khawar, Chloé Tessier +7 more

A simple liquid 3D cell culture paradigm models oxidative mitochondrial metabolism of epithelial breast cancer cells with relevance for lung metastases

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.24.671623

N/A

0DataRank · unranked

0 citations

Melissa R. Mikolaj, Jonathan M. Weiss, Ronald J. Holewinski, Yu Fan, Xia Xu +13 more

A simple circuit to sustain intact tumor microenvironments for complex drug interrogations

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.26.684624

N/A

0DataRank · unranked

0 citations

Samantha M. Ruff, Kirsten Remmert, Martha E. Teke, Emily A. Verbus, Areeba Saif +57 more

Functional characterization of the 9q34.13 locus identifies RAPGEF1 as modulating risk for melanoma and nevi via RAS activation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.03.691936

N/A

0DataRank · unranked

0 citations

Mai Xu, Alexandra Thornock, Joshuah Yon, Samuel Anyaso‐Samuel, Martin Lauss +28 more

Structure of E3 ligase E6AP with a proteasome-binding site provided by substrate receptor hRpn10

Nature Communications(2020)10.1038/s41467-020-15073-7

N/A

0DataRank · unranked

56 citations

Xiang Chen, Raj Chari, Maura O’Neill, Danielle L. Ebelle, Conor Jenkins +6 more

Multiple proteases are involved in mesothelin shedding by cancer cells

Communications Biology(2020)10.1038/s42003-020-01464-5

N/A

0DataRank · unranked

52 citations

Alexander Chan, Chin‐Hsien Tai, Þorkell Andrésson, Ira Pastan, Xiufen Liu

Evaluation of the Anti-Tumor Activity of the Humanized Monoclonal Antibody NEO-201 in Preclinical Models of Ovarian Cancer

Frontiers in Oncology(2020)10.3389/fonc.2020.00805

N/A

0DataRank · unranked

13 citations

Maria Pia Morelli, Justin M. David, Monica Neuman, Lídia Hernandez, Stephen M. Hewitt +12 more

LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies

Journal of Pharmaceutical and Biomedical Analysis(2020)10.1016/j.jpba.2020.113093

N/A

0DataRank · unranked

4 citations

King C. Chan, Jesse M. Jaynes, Zachary Knotts, Xia Xu, Abisola Abisoye-Ogunniyan +10 more

IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.20.000414

N/A

0DataRank · unranked

5 citations

Artem Pliss, Andrey N. Kuzmin, Tomohiro Yamasaki, Lumin Zhang, Tyrone Dowdy +15 more

MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

Molecular Cell(2021)10.1016/j.molcel.2021.11.016

N/A

0DataRank · unranked

118 citations

Vladislav Kuzin, Donald P. Cameron, Suzanne Sanford, Rajeev Jha, Zuqin Nie +11 more

IDH1 mutations induce organelle defects via dysregulated phospholipids

Nature Communications(2021)10.1038/s41467-020-20752-6

N/A

0DataRank · unranked

78 citations

Artem Pliss, Andrey N. Kuzmin, Tomohiro Yamasaki, Lumin Zhang, Tyrone Dowdy +15 more