Nina Isoherranen

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 48 papers. Top paper: “Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions”.

Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions

Journal of Lipid Research(2021)10.1016/j.jlr.2021.100046

N/A

0.864DataRank · unranked

28 citations

Aaron C. Ericsson, Guo Zhong, Nina Isoherranen, Chengsheng Zhu, YANA BROMBERG +11 more

Gut commensals expand vitamin A metabolic capacity of the mammalian host

Cell Host & Microbe(2022)10.1016/j.chom.2022.06.011

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0.635DataRank · unranked

68 citations

Lindsay C. Czuba, Geongoo Han, Guo Zhong, Hien Luong, Nina Isoherranen +2 more

Epithelium intrinsic vitamin A signaling co-ordinates pathogen clearance in the gut via IL-18

PLoS Pathogens(2020)10.1371/journal.ppat.1008360

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0.505DataRank · unranked

28 citations

Mayara Grizotte-Lake, Kellyanne Duncan, Sarah Gordon, Ana C. S. Palmer, Crystle Calvin +4 more

Do Inhibitory Metabolites Impact DDI Risk Assessment? Analysis of in vitro and in vivo Data from NDA Reviews Between 2013 and 2018

Clinical Pharmacology & Therapeutics(2021)10.1002/cpt.2259

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0.425DataRank · unranked

16 citations

Xinning Yang, Jingjing Yu, Hristina Dimova, Shiew‐Mei Huang, Isabelle Ragueneau‐Majlessi +2 more

Randomized controlled phase IIa clinical trial of safety, pharmacokinetics and pharmacodynamics of tenofovir and tenofovir plus levonorgestrel releasing intravaginal rings used by women in Kenya

Frontiers in Reproductive Health(2023)10.3389/frph.2023.1118030

N/A

0.425DataRank · unranked

7 citations

Victor Mudhune, Renee Heffron, Katherine K. Thomas, Eleanor McLellan–Lemal, Betty Njoroge +20 more

The Effects of Pregnancy on Amino Acid Levels and Nitrogen Disposition

Metabolites(2023)10.3390/metabo13020242

N/A

0.416DataRank · unranked

15 citations

Yuanyuan Shi, Emily Fay, Sue L. Moreni, Jennie Mao, Emma M. Honeyman +7 more

Regional heterogeneity of the blood-brain barrier

Nature Communications(2025)10.1038/s41467-025-61841-8

N/A

0.373DataRank · unranked

11 citations

Kaja Bajc, Benjamin D. Gastfriend, Caterina P. Profaci, Nadine Ruderisch, Cayce Dorrier +18 more

LX-2 Stellate Cells Are a Model System for Investigating the Regulation of Hepatic Vitamin A Metabolism and Respond to Tumor Necrosis Factor α and Interleukin 1β

Drug Metabolism and Disposition(2024)10.1124/dmd.124.001679

N/A

0.360DataRank · unranked

10 citations

Nina Isoherranen, Lindsay C. Czuba

Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes

Cannabis & Cannabinoid Research(2022)10.1089/can.2021.0068

N/A

0.312DataRank · unranked

7 citations

Lindsay C. Czuba, Jennifer A. Manuzak, Jeffrey N. Martin, Peter W. Hunt, Nichole R. Klatt +2 more

Power spectrum analysis of EEG in a translational nonhuman primate model after chronic exposure to low levels of the common marine neurotoxin, domoic acid

NeuroToxicology(2020)10.1016/j.neuro.2020.07.006

N/A

0.269DataRank · unranked

5 citations

Michael Murias, Kimberly S. Grant, Brenda Crouthamel, Noelle McKain, Sara Shum +4 more

Bridging the gap between in silico and in vivo by modeling opioid disposition in a kidney proximal tubule microphysiological system

Scientific Reports(2021)10.1038/s41598-021-00338-y

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0DataRank · unranked

31 citations

Weize Huang, Sara Shum, Dale W. Hailey, Shih‐Yu Chang, Alenka Chapron +5 more

Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000612

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0DataRank · unranked

24 citations

Danny D. Shen, Nina Isoherranen, Sara Shum

CRABPs Alter all-trans-Retinoic Acid Metabolism by CYP26A1 via Protein-Protein Interactions

Nutrients(2022)10.3390/nu14091784

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0DataRank · unranked

29 citations

Nina Isoherranen, King C. Yabut

Vitamin A homeostasis and cardiometabolic disease in humans: lost in translation?

Journal of Molecular Endocrinology(2022)10.1530/jme-22-0078

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0DataRank · unranked

19 citations

Nina Isoherranen, Katya B. Rubinow, Aprajita S. Yadav

Prolonged, Low-Level Exposure to the Marine Toxin, Domoic Acid, and Measures of Neurotoxicity in Nonhuman Primates

Environmental Health Perspectives(2022)10.1289/ehp10923

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0DataRank · unranked

19 citations

Christopher Williams, Jian‐Liang Li, James W. MacDonald, Theo K. Bammler, Todd L. Richards +11 more

Evidence of depot‐specific regulation of all‐trans‐retinoic acid biosynthesis in human adipose tissue

Clinical and Translational Science(2022)10.1111/cts.13259

N/A

0DataRank · unranked

13 citations

Guo Zhong, Lindsay C. Czuba, Judy Y. Chen, Estell Williams, Zoe Parr +5 more

Formation of the Major Circulating Metabolite of Cannabidiol by Non‐P450, Cytosolic Enzymes

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4072

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0DataRank · unranked

1 citations

Aurora Authement, Nina Isoherranen, Klarissa D. Jackson, Jessica L. Beers

Raising NAD + Level Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation

Circulation(2023)10.1161/circulationaha.123.066039

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0DataRank · unranked

39 citations

Hongye Chen, Aprajita S. Yadav, Julia Ritterhoff, Outi Villet, Timothy S. McMillen +7 more

Impact of Intracellular Lipid Binding Proteins on Endogenous and Xenobiotic Ligand Metabolism and Disposition

Drug Metabolism and Disposition(2023)10.1124/dmd.122.001010

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0DataRank · unranked

22 citations

Nina Isoherranen, King C. Yabut

Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol

ACS Medicinal Chemistry Letters(2023)10.1021/acsmedchemlett.3c00017

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0DataRank · unranked

21 citations

Aurora K. Authement, Nina Isoherranen, Klarissa D. Jackson, Jessica L. Beers

Temporal changes in the systemic concentrations of retinoids in pregnant and postpartum women

PLoS ONE(2023)10.1371/journal.pone.0280424

N/A

0DataRank · unranked

7 citations

Abigail T. Armstrong, Nina Isoherranen, Lindsay C. Czuba, Amy Yang, Katelynn Zumpf +5 more

CYP2D6 Activity Is Correlated with Changes in Plasma Concentrations of Taurocholic Acid during Pregnancy and Postpartum in CYP2D6 Extensive Metabolizers

Drug Metabolism and Disposition(2023)10.1124/dmd.123.001358

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0DataRank · unranked

5 citations

Karan Malhotra, Luke F. Enthoven, Emily Fay, Sue L. Moreni, Jennie Mao +6 more

Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease

Pharmaceutical Research(2023)10.1007/s11095-023-03594-x

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0DataRank · unranked

8 citations

Weize Huang, Alenka Chapron, Antonio Quinones, Joanne Wang, Nina Isoherranen +5 more

Predicting complex kidney drug handling using a physiologically‐based pharmacokinetic model informed by biomarker‐estimated secretory clearance and blood flow

Clinical and Translational Science(2023)10.1111/cts.13678

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0DataRank · unranked

4 citations

Weize Huang, Catherine K. Yeung, Nina Isoherranen, Bryan Kestenbaum, Michael L. Granda

The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro

Drug Metabolism and Disposition(2023)10.1124/dmd.123.001260

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0DataRank · unranked

1 citations

Abhinav Nath, Nina Isoherranen, Kenneth E. Thummel, Nathan Alade

Effect of isotretinoin on CYP2D6 and CYP3A activity in patients with severe acne

British Journal of Clinical Pharmacology(2023)10.1111/bcp.15938

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0DataRank · unranked

1 citations

Jay C. Vary, Aprajita S. Yadav, Lindsay C. Czuba, Sara Shum, Jeffrey LaFrance +4 more

Physiologically based pharmacokinetic modeling of small molecules: How much progress have we made?

Drug Metabolism and Disposition(2024)10.1124/dmd.123.000960

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0DataRank · unranked

25 citations

Nina Isoherranen

CYP2C9, CYP3A and CYP2C19 metabolize Δ9-tetrahydrocannabinol to multiple metabolites but metabolism is affected by human liver fatty acid binding protein (FABP1)

Biochemical Pharmacology(2024)10.1016/j.bcp.2024.116191

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0DataRank · unranked

21 citations

Yue Winnie Wen, Keiann T. Simon, Nina Isoherranen, King C. Yabut

The absorption, distribution, metabolism and elimination characteristics of small interfering RNA therapeutics and the opportunity to predict disposition in pregnant women

Drug Metabolism and Disposition(2024)10.1124/dmd.123.001383

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0DataRank · unranked

11 citations

Nina Isoherranen, Sara Shum, Ogochukwu Amaeze

Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose

Science Translational Medicine(2024)10.1126/scitranslmed.adk8446

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0DataRank · unranked

18 citations

Jong‐Won Kim, Junjie Zhu, Sihan Li, Jiong Yan, Qing Liu +21 more

Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism

Molecular Pharmacology(2024)10.1124/molpharm.124.000878

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0DataRank · unranked

9 citations

Alice Martynova, Abhinav Nath, Benjamin P. Zercher, Matthew F. Bush, Nina Isoherranen +1 more

Detection and Quantification of Drug–Protein Adducts in Human Liver

Journal of Proteome Research(2024)10.1021/acs.jproteome.4c00663

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0DataRank · unranked

8 citations

Michael Riffle, David Shteynberg, Guo Zhong, Ellen B. Riddle, Michael R. Hoopmann +6 more

The impact of pregnancy and associated hormones on the pharmacokinetics of Δ 9 -tetrahydrocannabinol

Expert Opinion on Drug Metabolism & Toxicology(2024)10.1080/17425255.2024.2309213

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0DataRank · unranked

5 citations

Nina Isoherranen, Aurora K. Authement

The interplay between retinoic acid binding proteins and retinoic acid degrading enzymes in modulating retinoic acid concentrations

Current topics in developmental biology/Current Topics in Developmental Biology(2024)10.1016/bs.ctdb.2024.09.001

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0DataRank · unranked

5 citations

Yue Winnie Wen, Nina Isoherranen

Role of metabolites in drug-drug interactions

Drug Metabolism and Pharmacokinetics(2025)10.1016/j.dmpk.2025.101511

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0DataRank · unranked

1 citations

Nina Isoherranen

Limelight: An Open, Web-Based Tool for Visualizing, Sharing, and Analyzing Mass Spectrometry Data from DDA Pipelines

Journal of Proteome Research(2025)10.1021/acs.jproteome.4c00968

N/A

0DataRank · unranked

3 citations

Alex Zelter, Daniel Jaschob, Michael R. Hoopmann, Danielle A. Faivre, Robert L. Moritz +4 more

Sex and Age but Not Body Mass Index (BMI) Predict Serum Retinol Binding Protein 4 (RBP4) and Transthyretin (TTR) Concentrations

The FASEB Journal(2025)10.1096/fj.202501772r

N/A

0DataRank · unranked

1 citations

Lindsay C. Czuba, Junwei Zhu, Jeffrey LaFrance, Aurora K. Authement, Lindsey N. Williams +8 more

Development and Validation of a Novel LC-MS/MS-Based Proteomics Method for Quantitation of Retinol Binding Protein 4 (RBP4) and Transthyretin (TTR)

Journal of Proteome Research(2025)10.1021/acs.jproteome.5c00679

N/A

0DataRank · unranked

0 citations

Katya B. Rubinow, Alex Zelter, Aurora K. Authement, Bryan Kestenbaum, John K. Amory +2 more

Dicloxacillin and flucloxacillin inhibit hepatic uptake transporters – in vitro investigations and physiologically based pharmacokinetic modelling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.21.683780

N/A

0DataRank · unranked

0 citations

Ogochukwu Amaeze, Jeroen JMW van den Heuvel, Tore Bjerregaard Stage, Jan B Koenderink, Nina Isoherranen +3 more

Maternal-fetal disposition of domoic acid following repeated oral dosing during pregnancy in nonhuman primate

Toxicology and Applied Pharmacology(2020)10.1016/j.taap.2020.115027

N/A

0DataRank · unranked

16 citations

Jing Jing, Rebekah Petroff, Brenda Crouthamel, Kimberly S. Grant, Thomas M. Burbacher +2 more

Mechanistic PBPK Modeling of Urine pH Effect on Renal and Systemic Disposition of Methamphetamine and Amphetamine

Journal of Pharmacology and Experimental Therapeutics(2020)10.1124/jpet.120.264994

N/A

0DataRank · unranked

20 citations

Lindsay C. Czuba, Nina Isoherranen, Weize Huang

Knockout of Cyp26a1 and Cyp26b1 during postnatal life causes reduced lifespan, dermatitis, splenomegaly, and systemic inflammation in mice

The FASEB Journal(2020)10.1096/fj.202001734r

N/A

0DataRank · unranked

28 citations

Guo Zhong, Cathryn A. Hogarth, Weize Huang, Traci Topping, Jeffrey LaFrance +6 more

Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000296

N/A

0DataRank · unranked

28 citations

Chris J. Seaman, Erickson M. Paragas, Huaqing Xi, Karla−Luise Herpoldt, Neil P. King +3 more

Analysis of vitamin A and retinoids in biological matrices

Methods in enzymology on CD-ROM/Methods in enzymology(2020)10.1016/bs.mie.2020.02.010

N/A

0DataRank · unranked

25 citations

Guo Zhong, King C. Yabut, Nina Isoherranen, Lindsay C. Czuba

Novel Mechanistic PBPK Model to Predict Renal Clearance in Varying Stages of CKD by Incorporating Tubular Adaptation and Dynamic Passive Reabsorption

CPT Pharmacometrics & Systems Pharmacology(2020)10.1002/psp4.12553

N/A

0DataRank · unranked

25 citations

Nina Isoherranen, Weize Huang

Knockout of Cyp26a1 and Cyp26b1 during post-natal life causes reduced lifespan, dermatitis, splenomegaly and systemic inflammation in mice

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.09.196170

N/A

0DataRank · unranked

2 citations

Guo Zhong, Cathryn A. Hogarth, Weize Huang, Traci Topping, Jeffrey LaFrance +6 more

Bridging the gap between in silico and in vivo: modeling opioid disposition in a kidney proximal tubule microphysiological system

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.412239

N/A

0DataRank · unranked

0 citations

Weize Huang, Sara Shum, Dale W. Hailey, Shih‐Yu Chang, Alenka Chapron +5 more

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19

Scientific Reports(2021)10.1038/s41598-021-83730-y

N/A

0DataRank · unranked

33 citations

Sandhya Subramanian, David E. Kim, Michael Murphy, Deleah Pettie, Lauren Carter +20 more