David V. Schaffer

Also affiliated with University of California, Berkeley

Biochemistry, Genetics and Molecular BiologyEngineering

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 41 papers. Top paper: “scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution”.

scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution

eLife(2021)10.7554/elife.64175

N/A

1.7DataRank · unranked

62 citations

Molly Johnson, Michael Kleyman, Serhan Turunç, Jing He, Sara Jabalameli +14 more

Genome-wide activation screens to increase adeno-associated virus production

Molecular Therapy — Nucleic Acids(2021)10.1016/j.omtn.2021.06.026

N/A

1.1DataRank · unranked

31 citations

Hyun‐Cheol Lee, David S. Ojala, Kazuomori K. Lewis, Prajit Limsirichai, David V. Schaffer +1 more

In vivo–directed evolution of adeno-associated virus in the primate retina

JCI Insight(2020)10.1172/jci.insight.135112

N/A

0.710DataRank · unranked

113 citations

Timothy P. Day, Meike Visel, Jennifer A. Strazzeri, Cécile Fortuny, Deniz Dalkara +4 more

In vivo hypermutation and continuous evolution

Nature Reviews Methods Primers(2022)10.1038/s43586-022-00130-w

N/A

0.612DataRank · unranked

58 citations

Gordon Rix, Amanuella A. Mengiste, Beatriz Álvarez, Daeje Seo, Haiqi Chen +16 more

Egr1 is a 3D matrix–specific mediator of mechanosensitive stem cell lineage commitment

Science Advances(2022)10.1126/sciadv.abm4646

N/A

0.587DataRank · unranked

49 citations

Paola A. Lopez, Sangmin Lee, Taek‐Soo Kim, Sanjay Kumar, David V. Schaffer +1 more

Optogenetic control of Wnt signaling models cell-intrinsic embryogenic patterning using 2D human pluripotent stem cell culture

Development(2023)10.1242/dev.201386

N/A

0.568DataRank · unranked

43 citations

Hunter J. Johnson, Xiaoping Bao, Joshua A. Zimmermann, David Joy, Shirley Z. Bi +3 more

Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices

Nature Neuroscience(2024)10.1038/s41593-024-01782-5

N/A

0.564DataRank · unranked

42 citations

Jinghui Geng, Kateryna Voitiuk, Matthew A.T. Elliott, David Shin, Ash Robbins +21 more

Substrate stress relaxation regulates neural stem cell fate commitment

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2317711121

N/A

0.510DataRank · unranked

29 citations

Camille Fulmore, David V. Schaffer, Sanjay Kumar, Eric Qiao

Evolving membrane-associated accessory protein variants for improved adeno-associated virus production

Molecular Therapy(2023)10.1016/j.ymthe.2023.12.015

N/A

0.506DataRank · unranked

11 citations

Hyun‐Cheol Lee, Aleysha T. Chen, Vindhya Kilaru, Justin Krish Williams, David V. Schaffer +1 more

Apodization Specific Fitting for Improved Resolution, Charge Measurement, and Data Analysis Speed in Charge Detection Mass Spectrometry

Journal of the American Society for Mass Spectrometry(2022)10.1021/jasms.2c00213

N/A

0.470DataRank · unranked

22 citations

Conner C. Harper, Hyun‐Cheol Lee, Amanda J. Bischoff, Matthew B. Francis, David V. Schaffer +2 more

Adeno-Associated Virus–Mediated Delivery of CRISPR–Cas Systems for Genome Engineering in Mammalian Cells

Cold Spring Harbor Protocols(2016)10.1101/pdb.prot086868

N/A

0.449DataRank · unranked

19 citations

David V. Schaffer, Thomas Gaj

Engineering novel adeno-associated viruses (AAVs) for improved delivery in the nervous system

Current Opinion in Chemical Biology(2024)10.1016/j.cbpa.2024.102532

N/A

0.449DataRank · unranked

19 citations

David V. Schaffer, A. Carneiro

Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.02.467003

N/A

0.434DataRank · unranked

17 citations

David H. Brookes, Akosua Busia, A. Carneiro, Clara Fannjiang, Galina Popova +7 more

High-throughput 3D screening for differentiation of hPSC-derived cell therapy candidates

Science Advances(2020)10.1126/sciadv.aaz1457

N/A

0.385DataRank · unranked

12 citations

Xiaoping Bao, Eric Tran, Evelyn Chen, Abirami Murugappan, Jonathan S. Dordick +3 more

N-Cadherin adhesive ligation regulates mechanosensitive neural stem cell lineage commitment in 3D matrices

Biomaterials Science(2022)10.1039/d2bm01349e

N/A

0.373DataRank · unranked

11 citations

Sanjay Kumar, David V. Schaffer, Sung Gap Im, Jieung Baek

Protocol to Fabricate Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics

STAR Protocols(2020)10.1016/j.xpro.2020.100141

N/A

0.373DataRank · unranked

11 citations

Hunter J. Johnson, Thomas McClave, Ravi S. Kane, David V. Schaffer, Nicole Repina

A scalable and tunable thermoreversible polymer for 3D human pluripotent stem cell biomanufacturing

iScience(2022)10.1016/j.isci.2022.104971

N/A

0.360DataRank · unranked

10 citations

Saheli Chakraborty, Riya Muckom, Nitash P. Balsara, David V. Schaffer, Hunter J. Johnson

Synaptic scale dopamine disruption in Huntington’s Disease model mice imaged with near infrared catecholamine nanosensors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.19.508617

N/A

0.269DataRank · unranked

5 citations

Jackson Travis Del Bonis-O’Donnell, Francesca Giordani, Jeffrey Wang, Alison Lui, David J. Piekarski +4 more

119. Engineering a Self-Inactivating CRISPR System for AAV Vectors

Molecular Therapy(2016)10.1016/s1525-0016(16)32928-8

N/A

0.269DataRank · unranked

5 citations

David V. Schaffer, Benjamin E. Epstein

Ocular Delivery of Viral Vectors for Retinal and Choroidal Vascular Diseases: A Review

American Journal of Ophthalmology(2025)10.1016/j.ajo.2025.07.025

N/A

0.208DataRank · unranked

3 citations

Sydney V. Oraskovich, Peter J. Francis, David V. Schaffer, Rajat Agrawal

3D Microenvironment-Specific Mechanosensing Regulates Neural Stem Cell Lineage Commitment

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.15.460399

N/A

0.208DataRank · unranked

3 citations

Paola A. Lopez, Sangmin Lee, Taek‐Soo Kim, Sanjay Kumar, David V. Schaffer +1 more

Simple, Affordable, and Modular Patterning of Cells using DNA

Journal of Visualized Experiments(2021)10.3791/61937-v

N/A

0DataRank · unranked

1 citations

David M. Patterson, Olivia J. Scheideler, Russell Cole, Adam R. Abate, David V. Schaffer +3 more

Simple, Affordable, and Modular Patterning of Cells using DNA

Journal of Visualized Experiments(2021)10.3791/61937

N/A

0DataRank · unranked

12 citations

David M. Patterson, Olivia J. Scheideler, Russell H. Cole, Adam R. Abate, David V. Schaffer +3 more

The AAV Vector Toolkit: Poised at the Clinical Crossroads

UNC Libraries(2020)10.17615/jrjj-rf40

N/A

0DataRank · unranked

0 citations

R. Jude Samulski, Aravind Asokan, David V. Schaffer

Optogenetic Application to Investigating Cell Behavior and Neurological Disease

Frontiers in Cellular Neuroscience(2022)10.3389/fncel.2022.811493

N/A

0DataRank · unranked

6 citations

Hunter J. Johnson, Jun Chen, David V. Schaffer, Danqing Zhu

The delivery challenge: fulfilling the promise of therapeutic genome editing

Nature Biotechnology(2020)10.1038/s41587-020-0565-5

N/A

0DataRank · unranked

292 citations

Jie Li, Olivia J. Scheideler, Niren Murthy, David V. Schaffer, Joost van Haasteren

Optogenetic Instruction of Cell Fate by Temporal Patterning of Mechanobiological Signals

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.14.508003

N/A

0DataRank · unranked

0 citations

Mason Sakamoto, Sanjay Kumar, David V. Schaffer, Rocío Sampayo

Wnt Regulates Proliferation and Neurogenic Potential of Müller Glial Cells via a Lin28/ let-7 miRNA-Dependent Pathway in Adult Mammalian Retinas

UNC Libraries(2020)10.17615/54az-rn94

N/A

0DataRank · unranked

0 citations

David V. Schaffer, Kai Yao, William D. Snider, John G. Flannery, Bo Chen +2 more

scAAVengr: Single-cell transcriptome-based quantification of engineered AAVs in non-human primate retina

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.01.323196

N/A

0DataRank · unranked

4 citations

Molly Johnson, Michael Kleyman, Serhan Turunç, Jing He, Sara Jabalameli +14 more

Optimal trade-off control in machine learning–based library design, with application to adeno-associated virus (AAV) for gene therapy

Science Advances(2024)10.1126/sciadv.adj3786

N/A

0DataRank · unranked

48 citations

David H. Brookes, Akosua Busia, A. Carneiro, Clara Fannjiang, Galina Popova +10 more

Recapitulating complex biological signaling environments using a multiplexed, DNA-patterning approach

Science Advances(2020)10.1126/sciadv.aay5696

N/A

0DataRank · unranked

44 citations

Yang Chun, Molly Kozminsky, Kira I. Mosher, Roberto Falcón‐Banchs, Emma C. Ciminelli +5 more

Advanced Materials to Enhance Central Nervous System Tissue Modeling and Cell Therapy

Advanced Functional Materials(2020)10.1002/adfm.202002931

N/A

0DataRank · unranked

16 citations

Rocío Sampayo, Hunter J. Johnson, David V. Schaffer, Riya Muckom

β-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2008509117

N/A

0DataRank · unranked

53 citations

Marcin Tarczyński, Nora Lam, Ravi S. Kane, Lukasz J. Bugaj, David V. Schaffer +1 more

Dynamic light-responsive RhoA activity regulates mechanosensitive stem cell fate decision in 3D matrices

Biomaterials Advances(2024)10.1016/j.bioadv.2024.213836

N/A

0DataRank · unranked

2 citations

Sanjay Kumar, David V. Schaffer, Jieung Baek

Advances in AAV capsid engineering: Integrating rational design, directed evolution and machine learning

Molecular Therapy(2025)10.1016/j.ymthe.2025.03.056

N/A

0DataRank · unranked

59 citations

Julio A. Rivera de Jesús, David V. Schaffer, Alan M. Nisanov

Nickase fidelity drives EvolvR-mediated diversification in mammalian cells

Nature Communications(2025)10.1038/s41467-025-58414-0

N/A

0DataRank · unranked

9 citations

Adam J. Schieferecke, Shakked O. Halperin, John Guan, Dylan Aidlen, David V. Schaffer +2 more

Adeno-associated virus serotype 9 structural heterogeneity and stability characterized by charge detection mass spectrometry

Molecular Therapy — Methods & Clinical Development(2025)10.1016/j.omtm.2025.101608

N/A

0DataRank · unranked

2 citations

Li Lin, David V. Schaffer, Evan R. Williams, Zachary M. Miller

The Application of DNA Viruses to Biotechnology

Viruses(2025)10.3390/v17030414

N/A

0DataRank · unranked

1 citations

Nadia Kuxhausen Ralph, David V. Schaffer, Adam J. Schieferecke

Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics

Cell Reports(2020)10.1016/j.celrep.2020.107737

N/A

0DataRank · unranked

73 citations

Thomas McClave, Hunter J. Johnson, Xiaoping Bao, Ravi S. Kane, David V. Schaffer +1 more

In vivo hypermutation and continuous evolution

Nature Reviews Methods Primers(2022)10.1038/s43586-022-00119-5

N/A

0DataRank · unranked

141 citations

Gordon Rix, Amanuella A. Mengiste, Beatriz Álvarez, Daeje Seo, Haiqi Chen +16 more

Effects of Molecular Size on Resolution in Charge Detection Mass Spectrometry

Analytical Chemistry(2022)10.1021/acs.analchem.2c02572

N/A

0DataRank · unranked

22 citations

Zachary M. Miller, Hyun‐Cheol Lee, Amanda J. Bischoff, Matthew B. Francis, David V. Schaffer +2 more