Ganes C. Sen

Cleveland Clinic Lerner College of Medicine

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 25 papers. Top paper: “PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation”.

PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation

eLife(2020)10.7554/elife.52241

N/A

1.2DataRank · unranked

34 citations

Dawid Krokowski, Bo‐Jhih Guan, Zhaofeng Gao, Xing‐Huang Gao, Jing Wu +15 more

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis

Nature Communications(2020)10.1038/s41467-020-14698-y

N/A

0.825DataRank · unranked

244 citations

Junjie Zhao, Katarzyna Bulek, Fangqiang Tang, Xing Chen, Gang Cai +12 more

EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions

The EMBO Journal(2020)10.15252/embj.2019104106

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0.648DataRank · unranked

74 citations

Xin Wang, Manoj Veleeparambil, Patricia Kessler, Belinda Willard, Saurabh Chattopadhyay +2 more

Regulation of Synthesis and Turnover of an Interferon-Inducible mRNA

Molecular and Cellular Biology(1986)10.1128/mcb.6.6.2062-2067.1986

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0.477DataRank · unranked

23 citations

Ganes C. Sen, Jyotirmoy Kusari

Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication

Journal of Virology(2020)10.1128/jvi.01717-19

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0DataRank · unranked

28 citations

Rameez Raja, Patricia Kessler, Ganes C. Sen, Muhammad Latif

Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis

PLoS Pathogens(2021)10.1371/journal.ppat.1009950

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0DataRank · unranked

33 citations

Chenyao Wang, Patricia Kessler, Ganes C. Sen, Nikhil Sharma

STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk

mBio(2021)10.1128/mbio.03228-21

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0DataRank · unranked

32 citations

Nikhil Sharma, Manoj Veleeparambil, Patricia Kessler, Belinda Willard, Ganes C. Sen +1 more

Innate Immune Responses to Herpesvirus Infection

Cells(2021)10.3390/cells10082122

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0DataRank · unranked

22 citations

Ganes C. Sen, Christine M. O’Connor

IRF3-mediated pathogenicity in a murine model of human hepatitis A

PLoS Pathogens(2021)10.1371/journal.ppat.1009960

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0DataRank · unranked

19 citations

You Li, Ichiro Misumi, Olga González‐López, Lucinda Hensley, John M. Cullen +8 more

The antiviral action of the RIG-I induced pathway of apoptosis (RIPA) is enhanced by its ability to degrade Otulin, which deubiquitinates IRF3

Cell Death and Differentiation(2021)10.1038/s41418-021-00870-4

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0DataRank · unranked

21 citations

Ganes C. Sen, Rameez Raja

IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2121385119

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0DataRank · unranked

59 citations

Sukanya Chakravarty, Shumin Fan, Anna Glanz, Siddhesh Aras, Laura E. Nagy +4 more

PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102050

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0DataRank · unranked

7 citations

Syed Muhammad Hamid, Aslı Yıldırım, Zehra Yıldırım, Ganes C. Sen, Céline E. Riera +3 more

IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.11.483954

N/A

0DataRank · unranked

0 citations

Nagendra Kumar, Amy Burrows, Sohee Kim, Ajai K. Tripathi, Samuel E. Weinberg +4 more

Ifit2 regulates murine-coronavirus spread to the spinal cord white matter and its associated myelin pathology

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.06.494972

N/A

0DataRank · unranked

0 citations

Debanjana Chakravarty, Ajay Zalavadia, Amy Burrows, Patricia Rayman, Nikhil Sharma +5 more

Intracranial delivery of antisense locked nucleic acids for silencing microRNAs in the mouse brain

STAR Protocols(2022)10.1016/j.xpro.2022.101836

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0DataRank · unranked

0 citations

Ganes C. Sen, Nikhil Sharma

STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2216953120

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0DataRank · unranked

18 citations

Nan Jing, Elise Holvey-Bates, Xing Chen, Samantha M. Wightman, Muhammad-Bilal Latif +6 more

Interferon induction by STING requires its translocation to the late endosomes

Traffic(2023)10.1111/tra.12918

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0DataRank · unranked

9 citations

Nikhil Sharma, Patricia Kessler, Ganes C. Sen, Chenyao Wang

IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity

The Journal of Immunology(2023)10.4049/jimmunol.2200746

N/A

0DataRank · unranked

8 citations

Nagendra Kumar, Amy Burrows, Sohee Kim, Ajai K. Tripathi, Samuel E. Weinberg +4 more

EGF-Receptor–Dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis

Laboratory Investigation(2023)10.1016/j.labinv.2023.100190

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0DataRank · unranked

7 citations

Suguru Saito, Ian R. Rifkin, Ramon Bonegio, Daniel N. Leal, Ganes C. Sen +3 more

Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses

Journal of Virology(2023)10.1128/jvi.01304-23

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0DataRank · unranked

10 citations

Patricia Kessler, Ganes C. Sen, Nikhil Sharma

Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology

Journal of Virology(2023)10.1128/jvi.00749-23

N/A

0DataRank · unranked

8 citations

Debanjana Chakravarty, Afaq Hussain, Ajay Zalavadia, Amy Burrows, Patricia Rayman +6 more

The interferon-induced protein, IFIT2, requires RNA-binding activity and neuronal expression to protect mice from intranasal vesicular stomatitis virus infection

mBio(2024)10.1128/mbio.00568-24

N/A

0DataRank · unranked

9 citations

Nikhil Sharma, Tomoaki Ogino, Xu Qi, Patricia Kessler, Hiran Mendries +3 more

Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.08.574713

N/A

0DataRank · unranked

0 citations

Xu Qi, Patricia Kessler, Ganes C. Sen, Nikhil Sharma

TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk

mBio(2025)10.1128/mbio.00276-25

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0DataRank · unranked

4 citations

Chenyao Wang, Patricia Kessler, Pracheta Sengupta, Santanu Das, Ritu Chakravarti +4 more

Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection

PLoS Pathogens(2020)10.1371/journal.ppat.1009034

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0DataRank · unranked

36 citations

Amy Burrows, Patricia Rayman, Mihyun Hwang, Soumya Kundu, Nikhil Sharma +3 more