David B. Sykes

Also affiliated with Harvard University Press, Massachusetts General Hospital, Harvard Stem Cell Institute

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 50 papers. Top paper: “Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses”.

Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses

Nature Communications(2023)10.1038/s41467-023-36325-2

N/A

5.9DataRank · unranked

257 citations

Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte Manouk Verhoeven +15 more

JAK inhibition in a patient with a STAT1 gain-of-function variant reveals STAT1 dysregulation as a common feature of aplastic anemia

Med(2022)10.1016/j.medj.2021.12.003

N/A

1.1DataRank · unranked

24 citations

Joshua M. Peters, Travis Hughes, Caleb A. Lareau, Leif S. Ludwig, Lucas R. Massoth +12 more

DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

eLife(2023)10.7554/elife.87292

N/A

0.889DataRank · unranked

36 citations

Surendra K. Shukla, Ravi Thakur, Sai Sundeep Kollala, Dezhen Wang, Nina V. Chaika +11 more

Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney

Journal of Clinical Investigation(2020)10.1172/jci131190

N/A

0.724DataRank · unranked

124 citations

Wondong Kim, Wen Zhou, Kerry A. Pierce, Wenhan Chang, David B. Sykes +20 more

A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

Nature Communications(2022)10.1038/s41467-022-33375-w

N/A

0.673DataRank · unranked

88 citations

Shenglin Mei, Ιωάννα Τσέα, Taghreed Hirz, Youmna Kfoury, Douglas M. Dahl +10 more

Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate

Genes & Development(2025)10.1101/gad.352316.124

N/A

0.364DataRank · unranked

9 citations

Brian Zhang, Jonah Frazier, Meijuan Chen, Brian T. Do, Sally Padayao +9 more

Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironment

Research Square(2022)10.21203/rs.3.rs-1489967/v1

N/A

0.165DataRank · unranked

2 citations

Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte Manouk Verhoeven +15 more

Integrated single-cell and spatial transcriptomic analyses unravel the heterogeneity of the prostate tumor microenvironment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.18.484781

N/A

0.104DataRank · unranked

1 citations

Shenglin Mei, Hirak Sarkar, Youmna Kfoury, Shulin Wu, Bronte Manouk Verhoeven +15 more

Chromatin-state barriers enforce an irreversible mammalian cell fate decision

Cell Reports(2021)10.1016/j.celrep.2021.109967

N/A

0DataRank · unranked

52 citations

David B. Sykes, Lei Gu, Mengjun Wu, Ricardo Petroni, Rahul Karnik +11 more

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia

iScience(2021)10.1016/j.isci.2021.102651

N/A

0DataRank · unranked

9 citations

Kamrine E. Poels, Cong-Hui Yao, Kimihito C. Kawabata, Gongwei Wu, Cihangir Duy +17 more

Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

iScience(2021)10.1016/j.isci.2021.102871

N/A

0DataRank · unranked

13 citations

Shuying Xu, Walter Adams, John M. Leong, Stephen C. Bunnell, Michael K. Mansour +3 more

Host defense against fungal pathogens: Adaptable neutrophil responses and the promise of therapeutic opportunities?

PLoS Pathogens(2021)10.1371/journal.ppat.1009691

N/A

0DataRank · unranked

11 citations

Alex Hopke, David B. Sykes, Daniel Irimia, Michael K. Mansour, Allison K. Scherer

A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

medRxiv(2021)10.1101/2021.01.27.21250464

N/A

0DataRank · unranked

4 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

Cyclophilin A regulates protein phase separation and mitigates haematopoietic stem cell aging

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.24.432737

N/A

0DataRank · unranked

4 citations

Polina Iakova, Shannon E. Moree, Jordon King, David B. Sykes, Cedric T. Hill +8 more

Chromatin state barriers enforce an irreversible mammalian cell fate decision

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.12.443709

N/A

0DataRank · unranked

3 citations

David B. Sykes, Lei Gu, Mengjun Wu, Ricardo Petroni, Rahul Karnik +11 more

tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.13.439696

N/A

0DataRank · unranked

1 citations

Fei Ji, Michael Mazzola, David B. Sykes, Allison K. Scherer, Anthony Anselmo +13 more

Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.02.433609

N/A

0DataRank · unranked

0 citations

Shuying Xu, Stephen C. Bunnell, Michael K. Mansour, David B. Sykes, Joan Mecsas +1 more

Inhibiting the biogenesis of myeloid-derived suppressor cells enhances immunotherapy efficacy against mammary tumor progression

Journal of Clinical Investigation(2022)10.1172/jci158661

N/A

0DataRank · unranked

48 citations

Andrea M. Amitrano, Robert Zollo, Jennifer Peresie, Elliot D. Kramer, Brian Morreale +9 more

DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma

JCI Insight(2022)10.1172/jci.insight.153836

N/A

0DataRank · unranked

44 citations

Cecilia Dyberg, Bethel Tesfai Embaie, Adele M. Alchahin, Jelena Milosevic, Jane Ding +12 more

Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity

Nature Communications(2022)10.1038/s41467-022-29730-6

N/A

0DataRank · unranked

36 citations

Yiming Guo, Shiyang He, Meijuan Chen, Fei Ji, Xinyue Zhou +16 more

Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging

Nature Methods(2022)10.1038/s41592-022-01673-2

N/A

0DataRank · unranked

36 citations

Karin Gustafsson, Shenglin Mei, Shu-Chi Yeh, Dmitry Richter, Jelena Milosevic +6 more

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Blood(2022)10.1182/blood.2021015108

N/A

0DataRank · unranked

30 citations

Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian +24 more

ENT1 blockade by CNX-774 overcomes resistance to DHODH inhibition in pancreatic cancer

Cancer Letters(2022)10.1016/j.canlet.2022.215981

N/A

0DataRank · unranked

28 citations

Ravi Thakur, Surendra K. Shukla, Nina V. Chaika, Sai Sundeep Kollala, Dezhen Wang +7 more

A new murine model of Barth syndrome neutropenia links TAFAZZIN deficiency to increased ER stress-induced apoptosis

Blood Advances(2022)10.1182/bloodadvances.2021005720

N/A

0DataRank · unranked

21 citations

Jelena Milosevic, Thomas Brouse, Najihah Aziz, Jenna Elkhoury, Suya Wang +9 more

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.16.503984

N/A

0DataRank · unranked

6 citations

Peggy P. Hsu, Sidney Y. Vermeulen, Zhishan Wang, Taghreed Hirz, Keene L. Abbott +21 more

A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.28.497333

N/A

0DataRank · unranked

0 citations

Shenglin Mei, Ιωάννα Τσέα, Taghreed Hirz, Youmna Kfoury, Douglas M. Dahl +10 more

Health Consequences of Thymus Removal in Adults

New England Journal of Medicine(2023)10.1056/nejmoa2302892

N/A

0DataRank · unranked

174 citations

Brody H. Foy, David B. Sykes, Karin Gustafsson, David T. Scadden, Kameron Kooshesh

Reversal of Lactate and PD-1–mediated Macrophage Immunosuppression Controls Growth of PTEN/p53-deficient Prostate Cancer

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-22-3350

N/A

0DataRank · unranked

126 citations

Hanna M. Hieromnimon, Rimpi Khurana, Brian Labadie, Taghreed Hirz, Shenglin Mei +19 more

Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities

Nature Communications(2023)10.1038/s41467-023-38447-z

N/A

0DataRank · unranked

17 citations

Shelby A. Auger, Jeffrey Lamb, Daisy Quellier, Cody Carter, On Tak To +10 more

Multiparametric Profiling of Neutrophil Function via a High-Throughput Flow Cytometry-Based Assay

Cells(2023)10.3390/cells12050743

N/A

0DataRank · unranked

13 citations

Daniel J. Floyd, Allison K. Scherer, Arianne J. Crossen, Johnny Atallah, Adam L. Viens +3 more

DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia

Blood Advances(2023)10.1182/bloodadvances.2023010337

N/A

0DataRank · unranked

13 citations

Gabriela Alexe, Karin Gustafsson, Elizabeth Zanetakos, Jelena Milosevic, Mary Ayres +5 more

Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors

Blood(2023)10.1182/blood.2023020257

N/A

0DataRank · unranked

11 citations

Elizabeth W. Scadden, Lai Ping Wong, Giulia Schiroli, Michael Mazzola, Phillip Chea +11 more

DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.03.535399

N/A

0DataRank · unranked

4 citations

Surendra K. Shukla, Ravi Thakur, Sai Sundeep Kollala, Dezhen Wang, Nina V. Chaika +11 more

Data from A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

(2023)10.1158/1078-0432.c.6530387

N/A

0DataRank · unranked

0 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

Data from A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

(2023)10.1158/1078-0432.c.6530387.v1

N/A

0DataRank · unranked

0 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

(2023)10.7554/elife.87292.1

N/A

0DataRank · unranked

0 citations

Surendra K. Shukla, Ravi Thakur, Sai Sundeep Kollala, Dezhen Wang, Nina V. Chaika +9 more

Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

Nature Cell Biology(2024)10.1038/s41556-024-01387-x

N/A

0DataRank · unranked

24 citations

Polina Iakova, Charles G. Lee, Shannon E. Moree, Xuan Lu, Gandhar Datar +15 more

Deferasirox, an iron chelator, impacts myeloid differentiation by modulating NF‐kB activity via mitochondrial ROS

British Journal of Haematology(2024)10.1111/bjh.19782

N/A

0DataRank · unranked

5 citations

Daniel Sadreyev, Elizabeth C. Trull, Kashish Chetal, Emma Yvanovich, Michael K. Mansour +3 more

Clonal Parabacteroides from Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn’s Disease Complications

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.09.574896

N/A

0DataRank · unranked

4 citations

Gail West, Claudio Fiocchi, Caryn E. Good, Jeffry Katz, Michael R. Jacobs +21 more

Multiomic analysis of clonal development reveals new regulators of leukemic cell growth

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.29.582846

N/A

0DataRank · unranked

1 citations

Alexander Morris, Sharmistha Kundu, Anthony Ducasse, Grace Kirkpatrick, Nathan Elias Jeffries +13 more

Author Response: DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

(2024)10.7554/elife.87292.2.sa4

N/A

0DataRank · unranked

0 citations

Surendra K. Shukla, Ravi Thakur, Sai Sundeep Kollala, Dezhen Wang, Nina V. Chaika +11 more

Optimal ex vivo production of functional neutrophils is dependent on the source of CD34+ human hematopoietic progenitors

Experimental Hematology(2025)10.1016/j.exphem.2025.105251

N/A

0DataRank · unranked

2 citations

Daniel J. Floyd, Nathan Elias Jeffries, Elizabeth C. Trull, Emma Yvanovich, Orion Furmanski +8 more

Differentiation stage-specific use of cap-independent and cap-dependent translation initiation in hematopoiesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.24.678136

N/A

0DataRank · unranked

0 citations

Ting Zhao, Anna Kiem, Trine Kristiansen, Karin Gustafsson, Lai Ping Wong +20 more

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

mBio(2020)10.1128/mbio.02043-19

N/A

0DataRank · unranked

39 citations

Shuying Xu, Zeina Dagher, Alex Hopke, Jennifer L. Reedy, Michael B. Feldman +16 more

SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

eLife(2020)10.7554/elife.56656

N/A

0DataRank · unranked

34 citations

Lamyaa Shaban, Matthias Mack, Kenneth D. Swanson, Stephen C. Bunnell, David B. Sykes +2 more

The Histone Chaperone CAF-1 Sustains Myeloid Lineage Identity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.22.350447

N/A

0DataRank · unranked

2 citations

Fei Ji, Jernej Murn, David Frankhouser, M. Andrés Blanco, Carmen Chiem +7 more

Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment

Cancer Cell(2021)10.1016/j.ccell.2021.09.005

N/A

0DataRank · unranked

282 citations

Ninib Baryawno, Nicolas Sévère, Shenglin Mei, Karin Gustafsson, Taghreed Hirz +13 more

KAT6A and ENL Form an Epigenetic Transcriptional Control Module to Drive Critical Leukemogenic Gene-Expression Programs

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1459

N/A

0DataRank · unranked

95 citations

Jinyang Li, Jelena Milosevic, Ricardo Petroni, Suying Liu, Zhennan Shi +17 more

A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-0121

N/A

0DataRank · unranked

48 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

tiRNA signaling via stress-regulated vesicle transfer in the hematopoietic niche

Cell stem cell(2021)10.1016/j.stem.2021.08.014

N/A

0DataRank · unranked

44 citations

Fei Ji, Michael Mazzola, David B. Sykes, Allison K. Scherer, Anthony Anselmo +14 more