David R. Liu

Also affiliated with Howard Hughes Medical Institute, Harvard University Press

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 94 papers. Top paper: “Methods for the directed evolution of proteins”.

Methods for the directed evolution of proteins

Nature Reviews Genetics(2015)10.1038/nrg3927

N/A

10.3DataRank · unranked

1009 citations

David R. Liu, Michael S. Packer

Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning

Nature Biotechnology(2021)10.1038/s41587-021-00938-z

N/A

4.9DataRank · unranked

208 citations

Mandana Arbab, Max W. Shen, Jeffrey A. Hussmann, Andrew V. Anzalone, Jordan L. Doman +10 more

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity

Nature Biotechnology(2022)10.1038/s41587-022-01533-6

N/A

3.8DataRank · unranked

267 citations

Alvin Hsu, Mandana Arbab, N Krasnow, Amber McElroy, Smriti Pandey +9 more

Proteolysis-targeting chimeras with reduced off-targets

Nature Chemistry(2023)10.1038/s41557-023-01379-8

N/A

3.6DataRank · unranked

123 citations

Vedagopuram Sreekanth, Arghya Deb, Praveen Kokkonda, Praveen K. Tiwari, Katherine A. Donovan +11 more

Phage-assisted continuous and non-continuous evolution

Nature Protocols(2020)10.1038/s41596-020-00410-3

N/A

2.9DataRank · unranked

126 citations

Tina Wang, David R. Liu, Shannon M. Miller

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Nature(2016)10.1038/nature17946

N/A

1.3DataRank · unranked

5340 citations

Yongjoo B. Kim, Michael S. Packer, John A. Zuris, David R. Liu, Y. Bill Kim +1 more

Multimodal small-molecule screening for human prion protein binders

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014905

N/A

0.934DataRank · unranked

29 citations

Michael F. Mesleh, Dominick Casalena, Sonia M. Vallabh, Jayme L. Dahlin, Alison Leed +21 more

Shuttle peptide delivers base editor RNPs to rhesus monkey airway epithelial cells in vivo

Nature Communications(2023)10.1038/s41467-023-43904-w

N/A

0.920DataRank · unranked

35 citations

Soumba Traore, Xue Cheng, Hadrien Benk-Fortin, Stéphanie Hallée, Mario Harvey +17 more

Determinants of Base Editing Outcomes from Target Library Analysis and Machine Learning

Cell(2020)10.1016/j.cell.2020.05.037

N/A

0.855DataRank · unranked

297 citations

Max W. Shen, Beverly Mok, Christopher Wilson, Żaneta Matuszek, Christopher A. Cassa +2 more

CRISPR-free base editors with enhanced activity and expanded targeting scope in mitochondrial and nuclear DNA

Nature Biotechnology(2022)10.1038/s41587-022-01256-8

N/A

0.803DataRank · unranked

210 citations

Anna V. Kotrys, Aditya Raguram, Tony P. Huang, Vamsi K. Mootha, David R. Liu +1 more

DNA capture by a CRISPR-Cas9–guided adenine base editor

Science(2020)10.1126/science.abb1390

N/A

0.803DataRank · unranked

210 citations

Gavin J. Knott, Cody M. Palumbo, Enrique Lin-Shiao, Michelle F. Richter, Kevin T. Zhao +4 more

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Nucleic Acids Research(2023)10.1093/nar/gkad1125

N/A

0.563DataRank · unranked

17 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +13 more

The dynamics of hematopoiesis over the human lifespan

Nature Methods(2024)10.1038/s41592-024-02495-0

N/A

0.489DataRank · unranked

25 citations

Parker Côté, Michael Kuoch, Jideofor Ezike, Katie Frenis, Anton Afanassiev +25 more

Scalable purification enables high-quality virus-like particles for therapeutic translation

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110946

N/A

0.111DataRank · unranked

1 citations

Fangyuan Gao, Samuel W. Du, Carolline Rodrigues Menezes, Jianye Zhang, Maria W. Hołubowicz +9 more

Phage-assisted evolution of botulinum neurotoxin proteases with reprogrammed specificity

Science(2021)10.1126/science.abf5972

N/A

0DataRank · unranked

78 citations

Hao Liu, Michael S. Packer, Xiaozhe Xiong, Pyung‐Gang Lee, Sicai Zhang +6 more

Laboratory evolution of a sortase enzyme that modifies amyloid-β protein

Nature Chemical Biology(2021)10.1038/s41589-020-00706-1

N/A

0DataRank · unranked

66 citations

Chihui An, Alexandra DeSousa, Brent M. Dorr, Dominic M. Walsh, David R. Liu +1 more

Functional correction ofCFTRmutations in human airway epithelial cells using adenine base editors

Nucleic Acids Research(2021)10.1093/nar/gkab788

N/A

0DataRank · unranked

59 citations

Soumba Traore, Ashley L. Cooney, Christian M. Brommel, Katarina Kulhánková, Patrick L. Sinn +4 more

Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing

Molecular Therapy(2021)10.1016/j.ymthe.2021.10.026

N/A

0DataRank · unranked

46 citations

Gregory A. Newby, Cindy Eide, Amber McElroy, Sarah C. Nielsen, Kyle D. Smith +16 more

Mechanisms of angiogenic incompetence in Hutchinson–Gilford progeria via downregulation of endothelial NOS

Aging Cell(2021)10.1111/acel.13388

N/A

0DataRank · unranked

29 citations

Luke W. Koblan, Xiaojing Mao, Mason Trappio, Bhushan Mahadik, John P. Fisher +3 more

A rechargeable anti-thrombotic coating for blood-contacting devices

Biomaterials(2021)10.1016/j.biomaterials.2021.121011

N/A

0DataRank · unranked

13 citations

Carolyn A. Haller, Guowei Su, Erbin Dai, Madhukar S. Patel, David R. Liu +3 more

Global-scale CRISPR gene editor specificity profiling by ONE-seq identifies population-specific, variant off-target effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.05.438458

N/A

0DataRank · unranked

39 citations

Daniel Y. Kim, Kanae Sasaki, Matthew C. Canver, Xiao Wang, Hina Shah +14 more

Proteolysis Targeting Chimeras With Reduced Off-targets

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.18.468552

N/A

0DataRank · unranked

14 citations

Vedagopuram Sreekanth, Arghya Deb, Praveen Kokkonda, Praveen K. Tiwari, Katherine A. Donovan +11 more

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

Cell(2022)10.1016/j.cell.2021.12.021

N/A

0DataRank · unranked

644 citations

Aditya Raguram, Susie Suh, Samuel W. Du, Jessie R. Davis, Elliot H. Choi +9 more

Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors

Nature Biomedical Engineering(2022)10.1038/s41551-022-00911-4

N/A

0DataRank · unranked

190 citations

Xiao Wang, Isaac P. Witte, Tony P. Huang, Jonathan M. Levy, Aditya Raguram +5 more

High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs

Nature Biotechnology(2022)10.1038/s41587-022-01410-2

N/A

0DataRank · unranked

111 citations

Zachary Heins, Shannon M. Miller, Brandon G. Wong, Pallavi A. Balivada, Tina Wang +3 more

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Nature Communications(2022)10.1038/s41467-022-29490-3

N/A

0DataRank · unranked

94 citations

Susie Suh, Andrzej T. Foik, Henri Leinonen, Gregory A. Newby, Xin D. Gao +11 more

Compact zinc finger base editors that edit mitochondrial or nuclear DNA in vitro and in vivo

Nature Communications(2022)10.1038/s41467-022-34784-7

N/A

0DataRank · unranked

67 citations

Pedro Silva-Pinheiro, Lily Widdup, Michal Minczuk, David R. Liu, Julian C. W. Willis

Precision genome editing in the eye

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2210104119

N/A

0DataRank · unranked

53 citations

Elliot H. Choi, Aditya Raguram, David R. Liu, Krzysztof Palczewski, Susie Suh

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Scientific Reports(2022)10.1038/s41598-022-24184-8

N/A

0DataRank · unranked

41 citations

Ina Guri, Paulina Żebrowska, Virginia Llopis-Hernández, Imogen Brooks, Stavroula Tekkela +14 more

Discovery and molecular basis of subtype-selective cyclophilin inhibitors

Nature Chemical Biology(2022)10.1038/s41589-022-01116-1

N/A

0DataRank · unranked

32 citations

Aziz M. Rangwala, Manish Thakur, Patrick S. Ward, Christie Hung, Ian R Outhwaite +6 more

Generating experimentally unrelated target molecule-binding highly functionalized nucleic-acid polymers using machine learning

Nature Communications(2022)10.1038/s41467-022-31955-4

N/A

0DataRank · unranked

22 citations

Jonathan P. Chen, Max W. Shen, Michael Wornow, Minwoo Bae, Wei-Hsi Yeh +3 more

Assigning functionality to cysteines by base editing of cancer dependency genes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.17.516964

N/A

0DataRank · unranked

9 citations

Jarrett R. Remsberg, Sang Joon Won, Kevin T. Zhao, Tony P. Huang, Bingwen Lu +4 more

Comprehensive Analysis of CRISPR Base Editing Outcomes for Multimeric Protein

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.20.496792

N/A

0DataRank · unranked

4 citations

Mariya Moosajee, Gregory A. Newby, Kaivalya Molugu, Krishanu Saha, David R. Liu +2 more

Nonviral base editing of KCNJ13 mutation preserves vision in an inherited retinal channelopathy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.12.499808

N/A

0DataRank · unranked

2 citations

Pawan K. Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane, Gregory A. Newby +12 more

Phage-assisted evolution and protein engineering yield compact, efficient prime editors

Cell(2023)10.1016/j.cell.2023.07.039

N/A

0DataRank · unranked

297 citations

Smriti Pandey, Monica E. Neugebauer, Meirui An, Jessie R. Davis, Peyton B. Randolph +12 more

Small-molecule discovery through DNA-encoded libraries

Nature Reviews Drug Discovery(2023)10.1038/s41573-023-00713-6

N/A

0DataRank · unranked

229 citations

David R. Liu, Alexander A. Peterson

Efficient prime editing in mouse brain, liver and heart with dual AAVs

Nature Biotechnology(2023)10.1038/s41587-023-01758-z

N/A

0DataRank · unranked

218 citations

Samagya Banskota, Jonathan M. Levy, Gregory A. Newby, Xiao Wang, Andrew V. Anzalone +9 more

Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice

Nature Medicine(2023)10.1038/s41591-022-02190-7

N/A

0DataRank · unranked

186 citations

Gregory A. Newby, Hiroko Wakimoto, Mingyue Lun, Joshua M. Gorham, Justin J. Curran +13 more

Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

Nature Biomedical Engineering(2023)10.1038/s41551-023-01026-0

N/A

0DataRank · unranked

146 citations

Gregory A. Newby, Rachel M. Levine, Kalin Mayberry, Yoonjeong Jang, Thiyagaraj Mayuranathan +15 more

Base editing rescue of spinal muscular atrophy in cells and in mice

Science(2023)10.1126/science.adg6518

N/A

0DataRank · unranked

135 citations

Żaneta Matuszek, Kaitlyn M. Kray, Ailing Du, Gregory A. Newby, Anton J. Blatnik +12 more

Massively parallel base editing to map variant effects in human hematopoiesis

Cell(2023)10.1016/j.cell.2023.03.035

N/A

0DataRank · unranked

128 citations

Nicole Castano, Michael Pang, Emanuelle I. Grody, Samantha Joubran, Alexis Caulier +20 more

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing

Cell(2023)10.1016/j.cell.2023.02.027

N/A

0DataRank · unranked

83 citations

Gloria Yiu, Patrick Chang, Gregory A. Newby, Beatriz Campo-Fernández, Sorel Fitz‐Gibbon +18 more

Potent and uniform fetal hemoglobin induction via base editing

Nature Genetics(2023)10.1038/s41588-023-01434-7

N/A

0DataRank · unranked

77 citations

Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Cícera R. Lazzarotto +22 more

Assigning functionality to cysteines by base editing of cancer dependency genes

Nature Chemical Biology(2023)10.1038/s41589-023-01428-w

N/A

0DataRank · unranked

63 citations

Tiantai Ma, Jarrett R. Remsberg, Sang Joon Won, Kristen E. DeMeester, Evert Njomen +11 more

A prime editor mouse to model a broad spectrum of somatic mutations in vivo

Nature Biotechnology(2023)10.1038/s41587-023-01783-y

N/A

0DataRank · unranked

59 citations

Nicolas Mathey‐Andrews, Santiago Naranjo, Samuel I. Gould, Kim L. Mercer, Gregory A. Newby +22 more

Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo

Nature Communications(2023)10.1038/s41467-023-40476-7

N/A

0DataRank · unranked

48 citations

Verónica Lamas, Wan Du, Wenliang Zhu, Yiran Li, Madelynn N. Whittaker +14 more

Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F

Molecular Therapy(2023)10.1016/j.ymthe.2023.06.007

N/A

0DataRank · unranked

37 citations

Killian S. Hanlon, Maryna V. Ivanchenko, Eric Zinn, Elizabeth Linarte, Yaqiao Li +6 more

Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy

Journal of Clinical Investigation(2023)10.1172/jci171356

N/A

0DataRank · unranked

29 citations

Pawan K. Shahi, Yuyuan Wang, Divya Sinha, Allison Spillane, Gregory A. Newby +12 more

Protospacer modification improves base editing of a canonical splice site variant and recovery of CFTR function in human airway epithelial cells

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.06.020

N/A

0DataRank · unranked

14 citations

Erin W. Kavanagh, Gregory A. Newby, Shakela Mitchell, Alice C. Eastman, Kathleen C. Paul +9 more

Reciprocal mutations of lung-tropic AAV capsids lead to improved transduction properties

Frontiers in Genome Editing(2023)10.3389/fgeed.2023.1271813

N/A

0DataRank · unranked

13 citations

Christian M. Brommel, Soumba Traore, Gregory A. Newby, David R. Liu, Paul B. McCray +2 more

Small-molecule binding and sensing with a designed protein family

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.01.565201

N/A

0DataRank · unranked

34 citations

Samuel J. Pellock, Christoffer Norn, Doug Tischer, Justas Dauparas, Ivan Anischenko +14 more

A molecular glue approach to control the half-life of CRISPR-based technologies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.12.531757

N/A

0DataRank · unranked

4 citations

Max Jan, Kevin T. Zhao, Donghyun Lim, Jessie R. Davis, Marie McConkey +14 more

Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.20.533459

N/A

0DataRank · unranked

1 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +11 more

Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo

Nature Biotechnology(2024)10.1038/s41587-023-02078-y

N/A

0DataRank · unranked

244 citations

Aditya Raguram, Samuel W. Du, Samagya Banskota, Jessie R. Davis, Gregory A. Newby +4 more

Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing

Nature Biomedical Engineering(2024)10.1038/s41551-024-01227-1

N/A

0DataRank · unranked

166 citations

Xin D. Gao, N Krasnow, Amber McElroy, Yong Tao, Jordyn E. Duby +9 more

Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells

Nature Nanotechnology(2024)10.1038/s41565-024-01680-8

N/A

0DataRank · unranked

120 citations

Sumanta Chatterjee, Yehui Sun, Sean A. Dilliard, Stephen D. Moore, Yufen Xiao +17 more

Branched chemically modified poly(A) tails enhance the translation capacity of mRNA

Nature Biotechnology(2024)10.1038/s41587-024-02174-7

N/A

0DataRank · unranked

114 citations

Dangliang Liu, Jianting Guo, Abhishek Aditham, Yiming Zhou, Jiakun Tian +9 more

Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations

Nature Biomedical Engineering(2024)10.1038/s41551-024-01296-2

N/A

0DataRank · unranked

81 citations

Samuel W. Du, Jiin Felgner, Roman Šmidák, Elliot H. Choi, Grażyna Palczewska +19 more

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

Science(2024)10.1126/science.adk4422

N/A

0DataRank · unranked

78 citations

Stephan J. DeCarlo, Shourya S. Roy Burman, Vedagopuram Sreekanth, Andrew T. Nelson, Moritz Hunkeler +10 more

High-throughput evaluation of genetic variants with prime editing sensor libraries

Nature Biotechnology(2024)10.1038/s41587-024-02172-9

N/A

0DataRank · unranked

67 citations

Alexandra Wuest, Kexin Dong, Grace A. Johnson, Alvin Hsu, Varun Narendra +5 more

Phage-assisted evolution of highly active cytosine base editors with enhanced selectivity and minimal sequence context preference

Nature Communications(2024)10.1038/s41467-024-45969-7

N/A

0DataRank · unranked

58 citations

Monica E. Neugebauer, N Krasnow, David R. Liu, Emily Zhang

Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells

Nature Biomedical Engineering(2024)10.1038/s41551-024-01233-3

N/A

0DataRank · unranked

57 citations

Colin Hemez, Lei Lei, Soumba Traore, Katarina Kulhánková, Gregory A. Newby +7 more

Efficient prime editing in two-cell mouse embryos using PEmbryo

Nature Biotechnology(2024)10.1038/s41587-023-02106-x

N/A

0DataRank · unranked

25 citations

Ryan McNulty, Bradley Joyce, Antonio Mollica, Peter J. Chen, Purnima Ravisankar +7 more

Post-translational modification-centric base editor screens to assess phosphorylation site functionality in high throughput

Nature Methods(2024)10.1038/s41592-024-02256-z

N/A

0DataRank · unranked

22 citations

Amin Alborzian Deh Sheikh, Matthew Balakar, Alexander C. Jones, Meagan E. Olive, Mudra Hegde +15 more

In vivo photoreceptor base editing ameliorates rhodopsin-E150K autosomal-recessive retinitis pigmentosa in mice

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2416827121

N/A

0DataRank · unranked

15 citations

Gregory A. Newby, David Salom, Fangyuan Gao, Carolline Rodrigues Menezes, Susie Suh +5 more

Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa

Journal of Investigative Dermatology(2024)10.1016/j.jid.2024.04.013

N/A

0DataRank · unranked

10 citations

Xin D. Gao, Amber McElroy, Smriti Pandey, Jordan L. Doman, Megan Riddle +12 more

Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cells

Nucleic Acids Research(2024)10.1093/nar/gkae819

N/A

0DataRank · unranked

9 citations

Anna X Cheng, Soumba Traore, Maud Auger, Mia Pelletier, Maxime Hervault +26 more

EvoAI enables extreme compression and reconstruction of the protein sequence space

Research Square(2024)10.21203/rs.3.rs-3930833/v1

N/A

0DataRank · unranked

3 citations

Zi-yuan Ma, Wenjie Li, Yunhao Shen, Yunxin Xu, Gengjiang Liu +9 more

Systematic empirical evaluation of individual base editing targets: validating therapeutic targets in USH2A and comparison of methods

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.02.615422

N/A

0DataRank · unranked

0 citations

Kannan Vrindavan Manian, Rossano Butcher, Jonathan M. Levy, Nachiket Pendse, Erin Hennessey +5 more

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

New England Journal of Medicine(2025)10.1056/nejmoa2504747

N/A

0DataRank · unranked

294 citations

Sarah Grandinette, Xiao Wang, Taylor R. Hudson, Kevin Briseno, Anne Marie Berry +40 more

In vivo base editing extends lifespan of a humanized mouse model of prion disease

Nature Medicine(2025)10.1038/s41591-024-03466-w

N/A

0DataRank · unranked

41 citations

Jessie R. Davis, Jonathan M. Levy, Fiona E. Serack, John W. Harvey, Pamela P. Brauer +22 more

In vivo base editing of Angptl3 via lipid nanoparticles to treat cardiovascular disease

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102486

N/A

0DataRank · unranked

17 citations

Hanan Bloomer, Douglas Wich, Changfeng Huang, J. Noah Workman, Yamin Li +4 more

Systematic empirical evaluation of individual base editing targets: Validating therapeutic targets in USH2A and comparison of methods

Molecular Therapy(2025)10.1016/j.ymthe.2025.01.042

N/A

0DataRank · unranked

11 citations

Kannan Vrindavan Manian, Rossano Butcher, Jonathan M. Levy, Nachiket Pendse, Erin Hennessey +5 more

Multiplex base editing to protect from CD33 directed drugs for immune and gene therapy

Nature Communications(2025)10.1038/s41467-025-59713-2

N/A

0DataRank · unranked

10 citations

Olivier Humbert, Jeffrey T. Ehmsen, Emily Fields, Sajeev Kohli, Stefan Radtke +14 more

Advancing gene-editing platforms to improve the viability of rare-disease therapeutics: key insights from a 2024 Scientific Exchange hosted by ARM, ISCT, and Danaher

Cytotherapy(2025)10.1016/j.jcyt.2025.06.010

N/A

0DataRank · unranked

8 citations

Sadik H. Kassim, Kiran Musunuru, David R. Liu, Ann Y. Lee, Luis Barrera +14 more

GFP-on mouse model for interrogation of in vivo gene editing

Nature Communications(2025)10.1038/s41467-025-61449-y

N/A

0DataRank · unranked

3 citations

Jack A. Queenan, Leah Swartzrock, Hana Willner, Morgane Denis, Nouraiz Ahmed +17 more

Engraftment and persistence of HBB base-edited hematopoietic stem cells in nonhuman primates

Science Translational Medicine(2025)10.1126/scitranslmed.adn2601

N/A

0DataRank · unranked

3 citations

Emily Fields, Kyle Swing, Greta Kanestrom, Jonathan Yen, Dnyanada Pande +7 more

TIGER: A tdTomato in vivo genome-editing reporter mouse for investigating precision-editor delivery approaches

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2506257122

N/A

0DataRank · unranked

4 citations

Grażyna Palczewska, Zhiqian Dong, Julie C. Lauterborn, Balasankara Reddy Kaipa, Alexander L. Yan +8 more

Adenine base editing rescues pathogenic phenotypes in tissue engineered vascular model of Hutchinson-Gilford progeria syndrome

APL Bioengineering(2025)10.1063/5.0244026

N/A

0DataRank · unranked

3 citations

Xin D. Gao, Akhil Bedapudi, Leandro Choi, Kevin L. Shores, Crystal C. Kennedy +5 more

Ultrasmall chemogenetic tags with group-transfer ligands

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.10.653252

N/A

0DataRank · unranked

1 citations

Shaimaa H. Sindi, Santosh Kumar Chaudhary, Rajaiah Pergu, Prashant Singh, Endri Karaj +9 more

In vivo prime editing rescues alternating hemiplegia of childhood in mice

Cell(2025)10.1016/j.cell.2025.06.038

N/A

0DataRank · unranked

33 citations

Markus Terrey, Holt A. Sakai, Christine Q. Simmons, Elena Arystarkhova, Natalia S. Morsci +14 more

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

Nature Biomedical Engineering(2020)10.1038/s41551-020-00632-6

N/A

0DataRank · unranked

168 citations

Elliot H. Choi, Henri Leinonen, Andrzej T. Foik, Gregory A. Newby, Wei-Hsi Yeh +6 more

Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis

Cell Reports(2020)10.1016/j.celrep.2020.107623

N/A

0DataRank · unranked

140 citations

Tiago C. Alves, Aharon Helman, Jonathan C. Chen, Jennifer Hyoje-Ryu Kenty, Rebecca Cardone +4 more

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses

Nature Biomedical Engineering(2020)10.1038/s41551-019-0501-5

N/A

0DataRank · unranked

500 citations

Wei-Hsi Yeh, Nachiket Pendse, Jessie R. Davis, Erin Hennessey, Rossano Butcher +5 more

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

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