Zhongyue Yang

Also affiliated with Joint Center for Structural Genomics, Institute of Chemical Biology and Fundamental Medicine, Vanderbilt Health

Biochemistry, Genetics and Molecular BiologyPhysics and Astronomy

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.606Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

IntEnzyDB: an Integrated Structure–Kinetics Enzymology Database

Journal of Chemical Information and Modeling(2022)10.1021/acs.jcim.2c01139

Top 33%

0.606DataRank

Top 33%22 citations

Xinchun Ran, Anvita Gollu, Zihao Cheng, Xiang Zhou, Yiwen Chen +2 more

Papers

Driven by 34 papers — median percentile 67. Top paper: “EnzyKR: a chirality-aware deep learning model for predicting the outcomes of the hydrolase-catalyzed kinetic resolution”.

EnzyKR: a chirality-aware deep learning model for predicting the outcomes of the hydrolase-catalyzed kinetic resolution

Chemical Science(2023)10.1039/d3sc02752j

N/A

0.727DataRank · unranked

22 citations

Yaoyukun Jiang, Qianzhen Shao, Zhongyue Yang, Xinchun Ran

Data-driven enzyme engineering to identify function-enhancing enzymes

Protein Engineering Design and Selection(2022)10.1093/protein/gzac009

N/A

0.648DataRank · unranked

21 citations

Xinchun Ran, Zhongyue Yang, Yaoyukun Jiang

Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

Cell Host & Microbe(2023)10.1016/j.chom.2023.08.018

N/A

0.628DataRank · unranked

65 citations

Ryan T. Fansler, Y. Randika Perera, Nicolas G. Shealy, Matthew J. Munneke, Holly E. David +13 more

IntEnzyDB: an Integrated Structure–Kinetics Enzymology Database

Journal of Chemical Information and Modeling(2022)10.1021/acs.jcim.2c01139

Top 33%

0.606DataRank

Top 33%22 citations

Xinchun Ran, Anvita Gollu, Zihao Cheng, Xiang Zhou, Yiwen Chen +2 more

High-Throughput Screen Reveals the Structure–Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin

ACS Central Science(2023)10.1021/acscentsci.2c01487

N/A

0.529DataRank · unranked

33 citations

Truc Do, Xinchun Ran, Mark P. Brynildsen, Zhongyue Yang, A. James Link +1 more

LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.2c00945

N/A

0.500DataRank · unranked

27 citations

Yaoyukun Jiang, Matthew Tremblay, Qianzhen Shao, A. James Link, Zhongyue Yang +1 more

Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase

Cell chemical biology(2021)10.1016/j.chembiol.2021.03.001

N/A

0.464DataRank · unranked

21 citations

Stephania M. Irwin, Lindsey R. F. Backman, Cong-Doan Le, Jennifer X. Wang, Vyshnavi Vennelakanti +5 more

Properties of Configurationally Stable Atropoenantiomers in Macrocyclic Natural Products and the Chrysophaentin Family

Accounts of Chemical Research(2023)10.1021/acs.accounts.2c00648

N/A

0.434DataRank · unranked

17 citations

Gary A. Sulikowski, Zhongyue Yang, Giuseppe Bifulco, Hyo Moon Cho, Christopher R. Fullenkamp +1 more

Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria

ACS Chemical Biology(2024)10.1021/acschembio.4c00009

N/A

0.405DataRank · unranked

7 citations

Reecan J. Juarez, Truc Do, Zhongyue Yang, A. James Link, Drew V. Carson

Substrate Positioning Dynamics Involves a Non-Electrostatic Component to Mediate Catalysis

The Journal of Physical Chemistry Letters(2023)10.1021/acs.jpclett.3c02444

N/A

0.373DataRank · unranked

11 citations

Ning Ding, Qianzhen Shao, Sebastian L. Stull, Zihao Cheng, Zhongyue Yang +1 more

LassoPred: a tool to predict the 3D structure of lasso peptides

Nature Communications(2025)10.1038/s41467-025-60544-4

N/A

0.360DataRank · unranked

10 citations

Xinchun Ran, Han Xu, Runeem Al-Abssi, Yi‐Lei Zhao, A. James Link +2 more

Mutexa: A Computational Ecosystem for IntelligentProtein Engineering

ChemRxiv(2023)10.26434/chemrxiv-2023-2cvbs

N/A

0.208DataRank · unranked

3 citations

Qianzhen Shao, Yaoyukun Jiang, Christopher Jurich, Xinchun Ran, Reecan J. Juarez +5 more

Linker‐mediated domain separation enhances cold adaptation in cellulases

Protein Science(2025)10.1002/pro.70198

N/A

0.165DataRank · unranked

2 citations

Ning Ding, Yaoyukun Jiang, Zhongyue Yang, Robbie Ge

Investigating the Non-Electrostatic Component of Substrate Positioning Dynamics

ChemRxiv(2023)10.26434/chemrxiv-2023-5510r

N/A

0.104DataRank · unranked

1 citations

Ning Ding, Qianzhen Shao, Sebastian L. Stull, Zihao Cheng, Zhongyue Yang +1 more

EnzyKR: A Chirality-Aware Deep Learning Model for Predicting the Outcomes of the Hydrolase-Catalyzed Kinetic Resolution

ChemRxiv(2023)10.26434/chemrxiv-2023-1sdkl

N/A

0.104DataRank · unranked

1 citations

Yukunyao Jiang, Qianzhen Shao, Zhongyue Yang, Xinchun Ran

Enzyme miniaturization: Revolutionizing future biocatalysts

Biotechnology Advances(2025)10.1016/j.biotechadv.2025.108598

N/A

0DataRank · unranked

6 citations

Yaoyukun Jiang, Sangsin Lee, Zihao Cheng, Xinchun Ran, Yujing Ding +4 more

Finding the dark matter: Large language model‐based enzyme kinetic data extractor and its validation

Protein Science(2025)10.1002/pro.70251

N/A

0DataRank · unranked

6 citations

Xinchun Ran, Runeem AI‐Abssi, Zhongyue Yang, Galen Wei

Combination nitazoxanide and auranofin treatment has synergistic anticancer activity in anaplastic thyroid cancer through enhanced activation of oxidative stress that leads to apoptosis

Cancer Letters(2025)10.1016/j.canlet.2025.217990

N/A

0DataRank · unranked

5 citations

Tejinder Pal Khaket, Viswanath Gunda, Zhongyue Yang, Jiangnan Hu, Eden Demissie Alamaw +8 more

Enhancing Cold Adaptation of Bidomain Amylases by High‐Throughput Computational Engineering

Angewandte Chemie International Edition(2025)10.1002/anie.202505991

N/A

0DataRank · unranked

2 citations

Yaoyukun Jiang, Robbie Ge, Qianzhen Shao, Wook Shin, Xinchun Ran +2 more

Dual Targeting of BRAF V600E and Ferroptosis Results in Synergistic Anticancer Activity via Iron Overload and Enhanced Oxidative Stress

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.25.661418

N/A

0DataRank · unranked

1 citations

Chandrayee Ghosh, Tejinder Pal Khaket, Zhongyue Yang, Yasmine Tabdili, Eden Demissie Alamaw +4 more

Convergence in determining enzyme functional descriptors across Kemp eliminase variants

Electronic Structure(2022)10.1088/2516-1075/acad51

N/A

0DataRank · unranked

8 citations

Sebastian L. Stull, Qianzhen Shao, Zhongyue Yang, Yaoyukun Jiang

A High-Throughput Screen Reveals the Structure-Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.13.520261

N/A

0DataRank · unranked

3 citations

Truc Do, Xinchun Ran, Mark P. Brynildsen, Zhongyue Yang, A. James Link +1 more

LassoHTP: a High-throughput Computational Tool for Lasso Peptide Structure Construction and Modeling

ChemRxiv(2022)10.26434/chemrxiv-2022-btvk9

N/A

0DataRank · unranked

1 citations

Matthew Tremblay, Yaoyukun Jiang, Qianzhen Shao, A. James Link, Zhongyue Yang +1 more

Convergence in Determining Enzyme Functional Descriptors across Kemp Eliminase Variants

ChemRxiv(2022)10.26434/chemrxiv-2022-8ts07-v2

N/A

0DataRank · unranked

1 citations

Sebastian L. Stull, Qianzhen Shao, Zhongyue Yang, Yaoyukun Jiang

Mutexa: A Computational Ecosystem for Intelligent Protein Engineering

Journal of Chemical Theory and Computation(2023)10.1021/acs.jctc.3c00602

N/A

0DataRank · unranked

23 citations

Qianzhen Shao, Yaoyukun Jiang, Christopher Jurich, Xinchun Ran, Reecan J. Juarez +5 more

EnzyHTP Computational Directed Evolution with Adaptive Resource Allocation

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.3c00618

N/A

0DataRank · unranked

23 citations

Yaoyukun Jiang, Zhongyue Yang, Qianzhen Shao

Effects of a genetic variant rs13266634 in the zinc transporter 8 gene (SLC30A8) on insulin and lipid levels before and after a high-fat mixed macronutrient tolerance test in U.S. adults

Journal of Trace Elements in Medicine and Biology(2023)10.1016/j.jtemb.2023.127142

N/A

0DataRank · unranked

9 citations

Yining E. Wang, Catherine P. Kirschke, Charles B. Stephensen, John W. Newman, Nancy L. Keim +3 more

High‐throughput computational investigation of protein electrostatics and cavity for SAM ‐dependent methyltransferases

Protein Science(2023)10.1002/pro.4690

N/A

0DataRank · unranked

8 citations

Zhongyue Yang, Christopher Jurich

High-Throughput Computational Investigation of Protein Electrostatics and Cavity for SAM-Dependent Methyltransferases

ChemRxiv(2023)10.26434/chemrxiv-2023-1hf5q

N/A

0DataRank · unranked

3 citations

Zhongyue Yang, Chris Jurich

Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.25.546471

N/A

0DataRank · unranked

3 citations

Ryan T. Fansler, Y. Randika Perera, Nicolas G. Shealy, Matthew J. Munneke, Teresa P. Torres +12 more

Investigating the Non-Electrostatic Component of Substrate Positioning Dynamics

ChemRxiv(2023)10.26434/chemrxiv-2023-5510r-v2

N/A

0DataRank · unranked

2 citations

Ning Ding, Qianzhen Shao, Sebastian L. Stull, Zihao Cheng, Zhongyue Yang +1 more

Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake

Cell(2024)10.1016/j.cell.2024.08.004

N/A

0DataRank · unranked

27 citations

Dongyu Li, Gonçalo Vale, Yaoyukun Jiang, Philip Schmiege, Zhongyue Yang +3 more

SubTuner leverages physics-based modeling to complement AI in enzyme engineering toward non-native substrates

Chem Catalysis(2025)10.1016/j.checat.2025.101334

N/A

0DataRank · unranked

16 citations

Asher C. Hollenbeak, Yaoyukun Jiang, Xinchun Ran, Brian O. Bachmann, Zhongyue Yang +1 more

Computational Studies of Enzymes for C−F Bond Degradation and Functionalization

ChemPhysChem(2025)10.1002/cphc.202401130

N/A

0DataRank · unranked

7 citations

Wook Shin, Zhongyue Yang, Kendra M. Cunningham

Zhongyue Yang

Indexed papers

Top data-sharing exemplar

Papers