Meenhard Herlyn

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

9.7Author DataRank

Indexed papers

7in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 7 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A promoter-level mammalian expression atlas

Nature(2014)10.1038/nature13182

Top 2%

8.9DataRank

Top 2%2192 citations

Alistair R. R. Forrest, J. Kenneth Baillie, Michiel de Hoon, Timo Lassmann, Ivan V. Kulakovskiy +262 more

Papers

Driven by 65 papers — median percentile 38. Top paper: “A promoter-level mammalian expression atlas”.

A promoter-level mammalian expression atlas

Nature(2014)10.1038/nature13182

Top 2%

8.9DataRank

Top 2%2192 citations

Alistair R. R. Forrest, J. Kenneth Baillie, Michiel de Hoon, Timo Lassmann, Ivan V. Kulakovskiy +262 more

Evolution of delayed resistance to immunotherapy in a melanoma responder

Nature Medicine(2021)10.1038/s41591-021-01331-8

N/A

3.6DataRank · unranked

137 citations

Jia‐Ren Lin, Emily Robitschek, Gyulnara G. Kasumova, Alex Heyde, Alvin Shi +35 more

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Nature Communications(2022)10.1038/s41467-022-28801-y

N/A

2.1DataRank · unranked

100 citations

Timothy J. Purwin, McKenna Q. Glasheen, Signe Caksa, Manoela Tiago, Nicole A. Wilski +17 more

Melanoma models for the next generation of therapies

Cancer Cell(2021)10.1016/j.ccell.2021.01.011

N/A

0.816DataRank · unranked

230 citations

Kristen L. Mueller, David J. Adams, Niroshana Anandasabapathy, Andrew E. Aplin, Corine Bertolotto +31 more

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Nature Genetics(2021)10.1038/s41588-020-00750-6

N/A

0.790DataRank · unranked

193 citations

Jessica Giordano, Anuj Srivastava, Min Jin Ha, Michael W. Lloyd, Roebi de Bruijn +57 more

Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy

Nature Communications(2021)10.1038/s41467-020-20600-7

N/A

0.784DataRank · unranked

185 citations

Thomas Connelly, Robin Choi, Hyeree Choi, Anastasia Samarkina, Ling Li +52 more

Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells

Nature(2023)10.1038/s41586-023-06342-8

N/A

0.782DataRank · unranked

183 citations

Gianna T. Busch, Maalavika Pillai, Jingxin Li, Ryan H. Boe, Emanuelle I. Grody +30 more

Stromal changes in the aged lung induce an emergence from melanoma dormancy

Nature(2022)10.1038/s41586-022-04774-2

N/A

0.781DataRank · unranked

181 citations

Yash Chhabra, Gretchen M. Alicea, Devon A. Maranto, Stephen M. Douglass, Marie R. Webster +17 more

Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines

Cancer Research(2020)10.1158/0008-5472.can-20-0291

N/A

0.729DataRank · unranked

128 citations

Amanda E.D. Van Swearingen, Carey K. Anders, Amos Bairoch, Adrienne Boire, Paula D. Bos +21 more

The State of Melanoma: Emergent Challenges and Opportunities

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-4092

N/A

0.705DataRank · unranked

109 citations

Clara Curiel‐Lewandrowski, David E. Fisher, Susan M. Swetter, Hensin Tsao, Julio A. Aguirre‐Ghiso +31 more

Patient-derived melanoma organoid models facilitate the assessment of immunotherapies

EBioMedicine(2023)10.1016/j.ebiom.2023.104614

N/A

0.675DataRank · unranked

89 citations

Shujing Liu, Huaishan Wang, Yeye Guo, Lei Guan, Longbin Shen +18 more

TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination

Nature Cell Biology(2021)10.1038/s41556-021-00732-8

N/A

0.673DataRank · unranked

88 citations

Meenhard Herlyn, Xiaolu Yang, Guixin Zhu

Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity

Nature Communications(2024)10.1038/s41467-024-44778-2

N/A

0.672DataRank · unranked

21 citations

Shishir M. Pant, Cecily C. Ritch, Hsin‐Yao Tang, Hongguang Shao, Harsh Dweep +14 more

HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors

Nature Communications(2022)10.1038/s41467-022-31713-6

N/A

0.668DataRank · unranked

85 citations

Bin Wu, Ting Li, Lynn A. Beer, Gaurav Sharma, Mingyue Li +23 more

The Anti-Melanoma Activity of Dinaciclib, a Cyclin-Dependent Kinase Inhibitor, Is Dependent on p53 Signaling

PLoS ONE(2013)10.1371/journal.pone.0059588

N/A

0.626DataRank · unranked

64 citations

Jessie Villanueva, Thierry-Thien K. Nguyen, Mercedes Lioni, Min Xiao, Jun Kong +7 more

Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma

Oncogene(2021)10.1038/s41388-021-01911-5

N/A

0.624DataRank · unranked

63 citations

Wei Zhang, Gao Zhang, Lawrence N. Kwong, Hezhe Lu, Jiufeng Tan +17 more

Tumor-Derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors

Cancer Research(2023)10.1158/0008-5472.can-22-2220

N/A

0.598DataRank · unranked

53 citations

Zebin Xiao, Zhiyuan Qin, Jingbo Yang, Yi Wen, Ziyan Yu +9 more

Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma

Nature Communications(2021)10.1038/s41467-021-26299-4

N/A

0.593DataRank · unranked

51 citations

Shiyou Wei, Zhi Wei, Dennie T. Frederick, Benchun Miao, Tabea Moll +10 more

Large-scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.03.186908

Top 34%

0.578DataRank

Top 34%10 citations

Jun Li, Mei‐Ju Chen, Zhenlin Ju, Nicole K. Nesser, Katie Johnson-Camacho +20 more

Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-2773

N/A

0.574DataRank · unranked

45 citations

Varsha Thakur, Yuan Li, Juliano T. Freitas, Patrick M. Zmina, Vijay S. Thakur +16 more

Costimulation of γδTCR and TLR7/8 promotes Vδ2 T-cell antitumor activity by modulating mTOR pathway and APC function

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-003339

N/A

0.524DataRank · unranked

32 citations

Hui Chen, Shujing Liu, Jie Zhang, Hezhe Lu, Rajasekharan Somasundaram +19 more

A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-0374

N/A

0.515DataRank · unranked

30 citations

Shiyou Wei, Milan R. Savani, Xiang Lin, Kuang Du, Ilgen Mender +33 more

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

Cancer Research(2021)10.1158/0008-5472.can-20-1496

N/A

0.489DataRank · unranked

25 citations

Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez +43 more

SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-20-0291

N/A

0.457DataRank · unranked

20 citations

Bertrand Fabre, Yongmei Feng, Ali Khateb, Patrick Turko, Julia M. Martínez Gómez +19 more

HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

Cell Reports(2023)10.1016/j.celrep.2023.113352

N/A

0.396DataRank · unranked

13 citations

Jiegang Yang, Beike Wang, Youtao Lu, Jingbo Yang, Wenqun Zhong +11 more

Nextflow pipeline for Visium and H&E data from patient-derived xenograft samples

Cell Reports Methods(2024)10.1016/j.crmeth.2024.100759

N/A

0.373DataRank · unranked

11 citations

Anuj Srivastava, Jessica Kaster, Haiyin Li, Meenhard Herlyn, Jill C. Rubinstein +2 more

Programmed Death Ligand-1 in Melanoma and Extracellular Vesicles Promotes Local and Regional Immune Suppression through M2-like Macrophage Polarization

American Journal Of Pathology(2024)10.1016/j.ajpath.2024.09.011

N/A

0.312DataRank · unranked

7 citations

Jingbo Yang, Jinjin Zhu, Huaishan Wang, Liyun Dong, Yeye Guo +16 more

Dasatinib Resensitizes MAPK Inhibitor Efficacy in Standard-of-Care Relapsed Melanomas

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.20.524923

N/A

0.269DataRank · unranked

5 citations

Min Xiao, Andrew V. Kossenkov, Tetiana Godok, Gregory Schuyler Brown, Dylan Fingerman +13 more

A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis

Cancer Research(2024)10.1158/0008-5472.can-23-1349

Top 62%

0.222DataRank

Top 62%3 citations

Xing Yi Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +49 more

Phylogenetic analysis of longitudinal melanoma samples to reveal convergent evolution and markers of immunotherapy resistance.

Journal of Clinical Oncology(2018)10.1200/jco.2018.36.15_suppl.9581

N/A

0.104DataRank · unranked

1 citations

Gao Zhang, Alvin Shi, Benjamin Izar, Alexander Heyde, Gyulnara G. Kasumova +14 more

ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ

Nature Methods(2022)10.1038/s41592-022-01653-6

N/A

0DataRank · unranked

47 citations

Benjamin Emert, Yogesh Goyal, Connie Jiang, Amanpreet Kaur, Jasmine Lee +8 more

Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0535

N/A

0DataRank · unranked

35 citations

Sandra L. Harper, Amanda M. Versace, Dylan Fingerman, Gregory Schuyler Brown, Monika Bhardwaj +11 more

Preclinical platforms to study therapeutic efficacy of human γδ T cells

Clinical and Translational Medicine(2022)10.1002/ctm2.814

N/A

0DataRank · unranked

36 citations

Huaishan Wang, Hui Huang, Zhiyan Zhou, Qiang Lin, Yeye Guo +10 more

fMetastatic potential in clonal melanoma cells is driven by a rare, early-invading subpopulation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.17.488591

N/A

0DataRank · unranked

4 citations

Luciann Cuenca, Karun Kiani, Gianna T. Busch, Dylan Fingerman, Margaret C. Dunagin +9 more

A pan-cancer PDX histology image repository with genomic and pathological annotations for deep learning analysis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.26.512745

Top 100%

0DataRank

Top 100%0 citations

X. Woo, Soner Koc, Todd Sheridan, Steven B. Neuhauser, Shidan Wang +45 more

ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression

Developmental Cell(2022)10.1016/j.devcel.2022.01.002

N/A

0DataRank · unranked

147 citations

Wenqun Zhong, Beike Wang, Jiegang Yang, Jingbo Yang, Ziyan Yu +15 more

NUMB as a Therapeutic Target for Melanoma

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.11.027

N/A

0DataRank · unranked

9 citations

Takeshi Fukumoto, Chihiro Takemori, Le Gao, Hua Xia, Joshua X. Wang +16 more

Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity

Cell Reports(2023)10.1016/j.celrep.2023.113224

N/A

0DataRank · unranked

78 citations

Youtao Lu, Xuexiang Han, Jingbo Yang, Zhiyuan Qin, Wei Zhang +20 more

Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies

Cancer Research(2021)10.1158/0008-5472.can-21-0164

N/A

0DataRank · unranked

13 citations

Hsu‐Min Sung, Christian Ickes, Christine S. Gibhardt, Adina Vultur, Hilal Bhat +19 more

Autophagy Paradox: Strategizing Treatment Modality in Melanoma

Current Treatment Options in Oncology(2023)10.1007/s11864-023-01053-8

N/A

0DataRank · unranked

21 citations

Xiaowei Xu, Meenhard Herlyn, Chengyu Liang, Christian R. Pangilinan

Targeting Upregulated cIAP2 in SOX10-Deficient Drug Tolerant Melanoma

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0025

N/A

0DataRank · unranked

13 citations

Signe Caksa, Amelia G. Young, Nicole A. Wilski, Connor A. Ott, Inna Chervoneva +6 more

Epigenetic Silencing of BMP6 by the SIN3A–HDAC1/2 Repressor Complex Drives Melanoma Metastasis via FAM83G/PAWS1

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-21-0289

N/A

0DataRank · unranked

15 citations

Jaemin Byun, Eun-Joon Lee, Abdul Aziz Khan, Christina Liu, Oliver Loudig +7 more

H3K4me3 remodeling induced acquired resistance through O-GlcNAc transferase

Drug Resistance Updates(2023)10.1016/j.drup.2023.100993

N/A

0DataRank · unranked

10 citations

Heinz Hammerlindl, Grégory Gimenez, Sabrina Hammerlindl, Elmar Zuegner, Joachim Torrano +15 more

Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0030

N/A

0DataRank · unranked

9 citations

Aaron R. Goldman, Hsin‐Yao Tang, Andrew V. Kossenkov, Heng Liu, Wei Zhou +4 more

Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth

Oncology Reports(2023)10.3892/or.2023.8481

N/A

0DataRank · unranked

2 citations

Xianghua Han, Christine W. Lary, Pradeep Sathyanarayana, Scot C. Remick, Marc S. Ernstoff +3 more

Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1351

N/A

0DataRank · unranked

65 citations

Tamer A. Ahmed, Maxwell R. Tucker, Peter M.U. Ung, Min Xiao, Zoi Karoulia +12 more

Data from Exploiting Allosteric Properties of RAF and MEK Inhibitors to Target Therapy-Resistant Tumors Driven by Oncogenic BRAF Signaling

(2023)10.1158/2159-8290.c.6549364

N/A

0DataRank · unranked

1 citations

Tamer A. Ahmed, Maxwell R. Tucker, Peter M.U. Ung, Min Xiao, Zoi Karoulia +12 more

Data from Epidermal Growth Factor Receptor and Mutant p53 Expand an Esophageal Cellular Subpopulation Capable of Epithelial-to-Mesenchymal Transition through ZEB Transcription Factors

(2023)10.1158/0008-5472.c.6500397

N/A

0DataRank · unranked

0 citations

Mitsuteru Natsuizaka, Gabrielle S. Wong, Carmen Z. Michaylira, Katharine D. Grugan, Douglas B. Stairs +10 more

Data from Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

(2023)10.1158/1078-0432.c.6529614

N/A

0DataRank · unranked

0 citations

Varsha Thakur, Yuan Li, Juliano T. Freitas, Patrick M. Zmina, Vijay S. Thakur +16 more

Data from Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E–mutated melanomas

(2023)10.1158/1535-7163.c.6532010

N/A

0DataRank · unranked

0 citations

Mercedes Lioni, Maurizia Dalla Palma, Min Xiao, Brijal Desai, Suzanne Egyházi +9 more

Data from Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma

(2023)10.1158/1078-0432.c.6529614.v1

N/A

0DataRank · unranked

0 citations

Varsha Thakur, Yuan Li, Juliano T. Freitas, Patrick M. Zmina, Vijay S. Thakur +16 more

Data from Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E–mutated melanomas

(2023)10.1158/1535-7163.c.6532010.v1

N/A

0DataRank · unranked

0 citations

Mercedes Lioni, Maurizia Dalla Palma, Min Xiao, Brijal Desai, Suzanne Egyházi +9 more

Data from A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas

(2023)10.1158/1078-0432.c.6531102.v1

N/A

0DataRank · unranked

0 citations

Shiyou Wei, Milan R. Savani, Xiang Lin, Kuang Du, Ilgen Mender +33 more

Spatiotemporal Profiling Defines Persistence and Resistance Dynamics during Targeted Treatment of Melanoma

Cancer Research(2024)10.1158/0008-5472.can-24-0690

N/A

0DataRank · unranked

11 citations

Sergii Domanskyi, Todd Sheridan, Brian J. Sanderson, SungHee Park, Jessica Kaster +5 more

A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

UNC Libraries(2020)10.17615/a8zp-dq08

Top 100%

0DataRank

Top 100%0 citations

Andrew E. Aplin, Yiling Lu, Sébastien Jeay, Carol L. Shields, Michal Barzily-Rokni +49 more

Combining DNA Damage Induction with BCL-2 Inhibition to Enhance Merkel Cell Carcinoma Cytotoxicity

Biology(2020)10.3390/biology9020035

N/A

0DataRank · unranked

13 citations

Nathan A. Krump, Meenhard Herlyn, Jianxin You, Wei Liu

Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma

Cell Death and Disease(2020)10.1038/s41419-020-03097-2

N/A

0DataRank · unranked

19 citations

Huiqin Chen, Gianluca Maddalo, Rainer Tuominen, Vito W. Rebecca, Meenhard Herlyn +4 more

AP-1 Mediates Cellular Adaptation and Memory Formation During Therapy Resistance

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.25.604999

N/A

0DataRank · unranked

14 citations

Pavithran T. Ravindran, Aoife O’Farrell, Gianna T. Busch, Ryan H. Boe, Zijian Niu +8 more

DR5 CAR-T cells target melanoma and suppress MDSCs with minimal toxicity

Molecular Therapy(2025)10.1016/j.ymthe.2025.12.025

N/A

0DataRank · unranked

1 citations

Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo +19 more

Heterogeneous therapy-resistant cancer cells have distinct and exploitable drug sensitivity profiles

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.25.650475

N/A

0DataRank · unranked

1 citations

Ryan H. Boe, Jingxin Li, Robert F. Gruener, Miles J. Arnett, Pavithran T. Ravindran +4 more

DR5 CAR-T cells target solid tumors and suppress MDSCs with minimal toxicity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.09.658618

N/A

0DataRank · unranked

0 citations

Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo +20 more

Modelling Acral Melanoma in Admixed Brazilians Uncovers Genomic Drivers and Targetable Pathways

medRxiv(2025)10.1101/2025.08.08.25332963

N/A

0DataRank · unranked

0 citations

Sara Santos Bernardes, Flavia C. Aguiar, Antonio C. Facciolo, Martín del Castillo Velasco Herrera, J. Rene C. Wong-Ramirez +25 more

Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.16.676608

N/A

0DataRank · unranked

0 citations

Yeqing Chen, Jessica Kaster, M. J. Dunne, Min Xiao, Ling Li +28 more

RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

Nature(2020)10.1038/s41586-020-03074-x

N/A

0DataRank · unranked

55 citations

Rishabh Sharma, Poli Adi Narayana Reddy, Prashanthi Vonteddu, Madeline Good, Anjana Sundarrajan +13 more

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0329

N/A

0DataRank · unranked

153 citations

Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera +17 more

Meenhard Herlyn

Indexed papers

Top data-sharing exemplar

Papers