Markus A. Seeliger

Also affiliated with Stony Brook University

MedicineComputer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.200Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome

Biomolecules(2022)10.3390/biom12050685

Top 65%

0.200DataRank

Top 65%2 citations

Victoria R. Mingione, George P. Georghiou, Markus A. Seeliger, Aziz M. Rangwala

Papers

Driven by 32 papers — median percentile 35. Top paper: “Structural mechanism of a drug-binding process involving a large conformational change of the protein target”.

Structural mechanism of a drug-binding process involving a large conformational change of the protein target

Nature Communications(2023)10.1038/s41467-023-36956-5

N/A

0.704DataRank · unranked

108 citations

Agatha Lyczek, YiTing Paung, Victoria R. Mingione, Roxana E. Iacob, Parker W. de Waal +5 more

IFITM proteins assist cellular uptake of diverse linked chemotypes

Science(2022)10.1126/science.abl5829

N/A

0.550DataRank · unranked

38 citations

Douglas R. Wassarman, Tangpo Yang, YiTing Paung, Ziyang Zhang, Thomas O’loughlin +9 more

Discovery and molecular basis of subtype-selective cyclophilin inhibitors

Nature Chemical Biology(2022)10.1038/s41589-022-01116-1

N/A

0.524DataRank · unranked

32 citations

Aziz M. Rangwala, Manish Thakur, Patrick S. Ward, Christie Hung, Ian R Outhwaite +6 more

Calculating Protein–Ligand Residence Times through State Predictive Information Bottleneck Based Enhanced Sampling

Journal of Chemical Theory and Computation(2024)10.1021/acs.jctc.4c00503

N/A

0.483DataRank · unranked

24 citations

Dedi Wang, Markus A. Seeliger, Pratyush Tiwary, Suemin Lee

Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding

The Journal of Physical Chemistry B(2025)10.1021/acs.jpcb.4c07794

N/A

0.373DataRank · unranked

11 citations

Vytautas Gapsys, Matteo Aldeghi, David Schaller, Aziz M. Rangwala, Jessica White +11 more

Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1

Cells(2023)10.3390/cells12060900

N/A

0.345DataRank · unranked

9 citations

YiTing Paung, Markus A. Seeliger, W. Todd Miller, Yağmur Kan

Resistance to Allosteric Inhibitors

Journal of Molecular Biology(2025)10.1016/j.jmb.2025.169133

N/A

0.241DataRank · unranked

4 citations

Isabelle Kwan, Ariel Leyte-Vidal, Neil P. Shah, İvet Bahar, Markus A. Seeliger +1 more

Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome

Biomolecules(2022)10.3390/biom12050685

Top 65%

0.200DataRank

Top 65%2 citations

Victoria R. Mingione, George P. Georghiou, Markus A. Seeliger, Aziz M. Rangwala

Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk

Biochemistry(2023)10.1021/acs.biochem.2c00685

N/A

0.165DataRank · unranked

2 citations

YiTing Paung, Yunyoung Kim, Markus A. Seeliger, W. Todd Miller, Yağmur Kan

Validation of an Allosteric Binding Site of Src Kinase Identified by Unbiased Ligand Binding Simulations

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167628

N/A

0DataRank · unranked

15 citations

Zachariah H. Foda, YiTing Paung, Hannah Philipose, Aziz M. Rangwala, Yibing Shan +2 more

Resistance to kinase inhibition through shortened target engagement

Molecular & Cellular Oncology(2022)10.1080/23723556.2022.2029999

N/A

0DataRank · unranked

5 citations

Benedict‐Tilman Berger, Matthew B. Robers, Stefan Knapp, Markus A. Seeliger, Aziz M. Rangwala

Extended DNA binding interface beyond the canonical SAP domain contributes to SDE2 function at DNA replication forks

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.09.490802

N/A

0DataRank · unranked

0 citations

YiTing Paung, Julie Rageul, Arafat Khan, Brian Ho, Michael Tong +4 more

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

The Journal of Cell Biology(2020)10.1083/jcb.201904048

N/A

0DataRank · unranked

67 citations

Eva Cloots, Mariska S. Simpson, Nicole Leduc, Yevgeniy V. Serebrenik, Heidi De Luca +10 more

Death by a thousand cuts through kinase inhibitor combinations that maximize selectivity and enable rational multitargeting

eLife(2023)10.7554/elife.86189

N/A

0DataRank · unranked

10 citations

Sukrit Singh, Benedict‐Tilman Berger, Stefan Knapp, John D. Chodera, Markus A. Seeliger +1 more

Death by a Thousand Cuts – Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.13.523972

N/A

0DataRank · unranked

1 citations

Sukrit Singh, Benedict‐Tilman Berger, Stefan Knapp, John D. Chodera, Markus A. Seeliger +1 more

Good Things Take Time: Tiwary–Seeliger Collaboration for Predictive Pharmacodynamics

Angewandte Chemie International Edition(2023)10.1002/anie.202303339

N/A

0DataRank · unranked

0 citations

Pratyush Tiwary, Markus A. Seeliger

Data from Equally Potent Inhibition of c-Src and Abl by Compounds that Recognize Inactive Kinase Conformations

(2023)10.1158/0008-5472.c.6499347.v1

N/A

0DataRank · unranked

0 citations

Pratistha Ranjitkar, Corynn Kasap, Yibing Shan, David E. Shaw, Neil P. Shah +3 more

Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib

Leukemia(2024)10.1038/s41375-024-02353-0

N/A

0DataRank · unranked

11 citations

RosaAnna DeFilippis, Ian R Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt +11 more

Allo-targeting of the kinase domain: Insights from in silico studies and comparison with experiments

Current Opinion in Structural Biology(2024)10.1016/j.sbi.2023.102770

N/A

0DataRank · unranked

9 citations

Emma Gebauer, Markus A. Seeliger, İvet Bahar, Ji Young Lee

SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis

Nature Communications(2024)10.1038/s41467-024-49978-4

N/A

0DataRank · unranked

8 citations

Dhivya Sridaran, Cody Weimholt, Jingqin Luo, Tiandao Li, Myles C. Hodgson +11 more

Lucanthone, a Potential PPT1 Inhibitor, Perturbs Stemness, Reduces Tumor Microtube Formation, and Slows the Growth of Temozolomide-Resistant Gliomas In Vivo

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.123.002021

N/A

0DataRank · unranked

8 citations

Sophie Shifman, Ian R Outhwaite, Aryan Sharma, Robert Bases, Markus A. Seeliger +2 more

Editorial overview: Molecular determinants, mechanisms, and state-of-the-art approaches in allostery

Current Opinion in Structural Biology(2024)10.1016/j.sbi.2024.102810

N/A

0DataRank · unranked

2 citations

Markus A. Seeliger, Igor N. Berezovsky

Calculating Protein-Ligand Residence Times Through State Predictive Information Bottleneck based Enhanced Sampling

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.16.589710

N/A

0DataRank · unranked

1 citations

Dedi Wang, Markus A. Seeliger, Pratyush Tiwary, Suemin Lee

Allosteric regulation and inhibition of protein kinases

Biochemical Society Transactions(2023)10.1042/bst20220940

N/A

0DataRank · unranked

43 citations

YiTing Paung, Ian R Outhwaite, Markus A. Seeliger, Victoria R. Mingione

1_manuscript_2020-04-14.pdf

ChemRxiv(2020)10.26434/chemrxiv.12148524.v1

N/A

0DataRank · unranked

0 citations

Jessica Vilas-Boas, Sujata Chakraborty, zachary potter, Ames C. Register, Markus A. Seeliger +2 more

How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture

ChemRxiv(2020)10.26434/chemrxiv.12148524

N/A

0DataRank · unranked

0 citations

Jessica Vilas-Boas, Sujata Chakraborty, zachary potter, Ames C. Register, Markus A. Seeliger +2 more

How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture

ChemRxiv(2020)10.26434/chemrxiv.12148524.v2

N/A

0DataRank · unranked

0 citations

Jessica Vilas-Boas, Sujata Chakraborty, zachary potter, Ames C. Register, Markus A. Seeliger +2 more

Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2111451118

N/A

0DataRank · unranked

73 citations

Benedict‐Tilman Berger, Aziz M. Rangwala, YiTing Paung, Jessica Tom, Hannah Philipose +7 more

Mutation in Abl kinase with altered drug binding kinetics indicates a novel mechanism of imatinib resistance

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.28.449968

N/A

0DataRank · unranked

4 citations

Benedict‐Tilman Berger, Aziz M. Rangwala, YiTing Paung, Jessica Tom, Hannah Philipose +7 more

Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance

Nature Communications(2022)10.1038/s41467-022-34724-5

N/A

0DataRank · unranked

58 citations

Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat +10 more

Protein Flexibility and Dissociation Pathway Differentiation Can Explain Onset of Resistance Mutations in Kinases**

Angewandte Chemie International Edition(2022)10.1002/anie.202200983

N/A

0DataRank · unranked

51 citations

Zachary Smith, Markus A. Seeliger, Pratyush Tiwary, Mrinal Shekhar

Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102268

N/A

0DataRank · unranked

18 citations

YiTing Paung, Julie Rageul, Arafat Khan, Natalie Lo, Brian Ho +5 more

Markus A. Seeliger

Indexed papers

Top data-sharing exemplar

Papers