Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome is a dataset published in Biomolecules (2022). On theSindex it has a DataRank of 0.200, placing it in the top 65.2% of the data-sharing corpus. It has been cited 2 times, with 2 citing works in its 1-hop citation network. Its calibrated FAIR score is 29/100.
Ranks in the top 65% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
No persistent identifier is given for the study's own data; the supplementary link is a URL, not a PID scheme. [majority verdict 'no' (3/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
No repository is named as the holder of the study's data; the data are in the journal's supplementary materials. [majority verdict 'no' (3/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
The dataset (the list of kinases) does not appear in the reference list. [majority verdict 'no' (3/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“Data Availability Statement Not applicable.”
The data availability statement declares the data are not applicable, offering no route to data.
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“Table 1 Unique bifunctional kinases in the UniProtKB database.”
Table 1 is an itemised inventory of the dataset's records. [majority verdict 'yes' (3/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/biom12050685/s1”
The supplementary materials are accessible via a direct link with no stated precondition. [majority verdict 'yes' (3/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/biom12050685/s1”
The paper describes an action (a download link) but does not provide an explicit access-level label for the data. [majority verdict 'partial' (3/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
The data are not sensitive/human-subject, and no gatekeeper is mentioned.
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
The paper does not mention any timeline for data availability or retention. [majority verdict 'no' (4/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
No file format is named for the supplementary data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
The paper uses UniProtKB and EC numbers but these are not applied to the paper's own data, which is absent. [majority verdict 'no' (2/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
“We mined the UniProtKB (release version 2022_01)”
The paper provides the UniProtKB release version and accession numbers for the kinases, which are identifiers for external resources. [majority verdict 'yes' (3/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
“This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.”— not found in the paper; verdict downgraded
The CC BY license is stated for the article, which includes the supplementary data. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (2/5 passes agreed)]
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is given for the study's own dataset. [majority verdict 'no' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
No code is provided or mentioned.
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“This work was funded by NIH R35 GM119437 (M.A.S.), NIH F30 CA260771 (A.M.R.), NIH T32 GM008444 (A.M.R.), and NIH T32 GM127253 (V.R.M.).”
The paper lists specific NIH award numbers. [majority verdict 'yes' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“We mined the UniProtKB (release version 2022_01), SwissProt, and TrEMBL databases with a search strategy designed to identify Ser/Thr, Tyr, and dual-specificity kinases based on Enzyme Commission (EC) classification numbers.”— not found in the paper; verdict downgraded
The paper names the specific software (UniProtKB) and the search algorithm as the tool for data generation. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“Table 1 Unique bifunctional kinases in the UniProtKB database.”
Variable definitions are provided inside the article in Table 1; no separate documentation object is named. [majority verdict 'partial' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.165
From this paper's citation signal
Citation Network Contribution
0.0347
From 2 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 2 citers.
NIH
Grant: R35 GM119437
NIH
Grant: F30 CA260771
NIH
Grant: T32 GM008444
NIH
Grant: T32 GM127253
National Institutes of Health
Grant: 2T32GM008444-24
Medical Scientist Training Program
National Institutes of Health
Grant: 3R35GM119437-09S1
Dynamics of Ligand Binding and Protein Kinase Regulation
National Institutes of Health
Grant: 5F30CA260771-02
Elucidating the Role of Binding Kinetics in the Development of Abl Kinase Drug Resistance
National Institutes of Health
Grant: 5T32GM127253-02
Scholars in BioMedical Sciences (SBMS) Training Program
FWCI
0.16
Citation Percentile
0.4%
Citation Trend
Fields of Study
MeSH Terms
Keywords
Sustainable Development Goals