Margaret A. Goodell

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome”.

Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome

eLife(2020)10.7554/elife.52981

N/A

1.4DataRank · unranked

58 citations

Kerstin Ure, Ying‐Wooi Wan, Chongyuan Luo, Alexander J. Trostle, Wei Wang +12 more

Ageing and rejuvenation of tissue stem cells and their niches

Nature Reviews Molecular Cell Biology(2022)10.1038/s41580-022-00510-w

N/A

0.892DataRank · unranked

381 citations

Margaret A. Goodell, Thomas A. Rando, Anne Brunet

SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation

Cell stem cell(2023)10.1016/j.stem.2023.09.011

N/A

0.729DataRank · unranked

26 citations

Linda Zhang, Ravi Dutta, Abhishek Niroula, Peter G. Miller, Christopher J. Gibson +16 more

Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity

Molecular Cell(2020)10.1016/j.molcel.2020.04.018

N/A

0.686DataRank · unranked

96 citations

Mira Jeong, Xingfan Huang, Xue Qing David Wang, Xinyu Wang, Wanding Zhou +16 more

Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor

Cancer Discovery(2021)10.1158/2159-8290.cd-21-0560

N/A

0.666DataRank · unranked

84 citations

Chun-Wei Chen, Venkatasubramaniam Sundaramurthy, Mikołaj Słabicki, Dapeng Hao, Caroline J. Watson +20 more

SOD1 is a synthetic lethal target in PPM1D -mutant leukemia cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.31.555634

N/A

0.165DataRank · unranked

2 citations

Joanne I. Hsu, Étienne De Braekeleer, Chun-Wei Chen, Tajhal D. Patel, Alejandra G. Martell +19 more

SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells

eLife(2023)10.7554/elife.91611

N/A

0.104DataRank · unranked

1 citations

Joanne I. Hsu, Étienne De Braekeleer, Chun-Wei Chen, Tajhal D. Patel, Alejandra G. Martell +19 more

Dnmt3a is essential for hematopoietic stem cell differentiation

UNC Libraries(2020)10.17615/nj45-sr35

N/A

0.104DataRank · unranked

1 citations

Yue Lu, Jonathan S. Berg, Jaroslav Jelı́nek, Wei Li, Yuanxin Xi +13 more

Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL

Cancer Research(2021)10.1158/0008-5472.can-21-1027

N/A

0DataRank · unranked

13 citations

Vijay Negi, Yang Jo Chung, Masahiro Onozawa, Yuelin J. Zhu, Robert L. Walker +9 more

Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities

Blood Advances(2021)10.1182/bloodadvances.2020002408

N/A

0DataRank · unranked

10 citations

Rohit Gupta, Jaime M. Reyes, Michael C. Gundry, Geraldo Medrano, Anna Guzman +11 more

Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.13.460063

N/A

0DataRank · unranked

0 citations

Jaime M. Reyes, Linda Zhang, Yung‐Hsin Huang, Carina Rosas, Alexes C. Daquinag +13 more

Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain

Nature Aging(2022)10.1038/s43587-022-00335-4

N/A

0DataRank · unranked

182 citations

Eric Sun, Benson M. George, Ling Liu, Nicholas Schaum, Lucy Xu +7 more

The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development

Nature Genetics(2022)10.1038/s41588-022-01063-6

N/A

0DataRank · unranked

88 citations

Dapeng Hao, Junsung Woo, Teng-Wei Huang, Lei Guo, Xueqiu Lin +10 more

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.12.475145

N/A

0DataRank · unranked

10 citations

Soochi Kim, Matthew T. Buckley, Jaime M. Reyes, Jengmin Kang, Lei Tian +11 more

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging

Cell stem cell(2023)10.1016/j.stem.2023.03.016

N/A

0DataRank · unranked

99 citations

Soochi Kim, Matthew T. Buckley, Jaime M. Reyes, Jengmin Kang, Lei Tian +11 more

Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors

JCO Precision Oncology(2023)10.1200/po.23.00070

N/A

0DataRank · unranked

19 citations

Miika Mehine, Ryan Ptashkin, Kelly L. Bolton, Chaitanya Bandlamudi, Preethi Srinivasan +18 more

DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells

Nature Cell Biology(2023)10.1038/s41556-023-01109-9

N/A

0DataRank · unranked

27 citations

Jarey H. Wang, Jaime M. Reyes, Anna Guzman, Sinjini Gupta, Carina Rosas +17 more

Incipient clonal hematopoiesis is accelerated following CD30.CAR-T therapy

Cytotherapy(2023)10.1016/j.jcyt.2023.11.013

N/A

0DataRank · unranked

9 citations

G. Rosas, Sachin G. Thakkar, Meng-Fen Wu, Virginia Torrano, Tao Wang +6 more

Data from Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL

(2023)10.1158/0008-5472.c.6513534.v1

N/A

0DataRank · unranked

0 citations

Vijay Negi, Yang Jo Chung, Masahiro Onozawa, Yuelin J. Zhu, Robert L. Walker +9 more

SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

(2023)10.7554/elife.91611.1

N/A

0DataRank · unranked

0 citations

Joanne I. Hsu, Étienne De Braekeleer, Chun-Wei Chen, Tajhal D. Patel, Hidetaka Urya +18 more

Author Response: SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

(2023)10.7554/elife.91611.1.sa2

N/A

0DataRank · unranked

0 citations

Joanne I. Hsu, Étienne De Braekeleer, Chun-Wei Chen, Tajhal D. Patel, Hidetaka Urya +18 more

Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

Nature Cell Biology(2024)10.1038/s41556-024-01387-x

N/A

0DataRank · unranked

24 citations

Polina Iakova, Charles G. Lee, Shannon E. Moree, Xuan Lu, Gandhar Datar +15 more

Distinct landscape and clinical implications of therapy-related clonal hematopoiesis

Journal of Clinical Investigation(2024)10.1172/jci180069

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0DataRank · unranked

22 citations

Daisuke Nakada, Margaret A. Goodell, Koichi Takahashi

Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation

iScience(2024)10.1016/j.isci.2024.109122

N/A

0DataRank · unranked

12 citations

Ayala Tovy, Linda Zhang, Angelina S. Bortoletto, Carina Rosas, Chun‐Wei Chen +16 more

Mutant NPM1 marginally impacts ribosome footprint in acute myeloid leukemia cells

eJHaem(2024)10.1002/jha2.996

N/A

0DataRank · unranked

3 citations

Giulia Pianigiani, Michael C. Gundry, Margaret A. Goodell, Brunangelo Falini, Lorenzo Brunetti

Dose-dependent effects of Dnmt3a in an inducible murine model of Kras-driven leukemia

Experimental Hematology(2024)10.1016/j.exphem.2024.104248

N/A

0DataRank · unranked

1 citations

Allison B. Rosen, Jaime M. Reyes, Shamika Ketkar, Shannon E. Conneely, Rohit Gupta +8 more

Author Response: SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

(2024)10.7554/elife.91611.2.sa4

N/A

0DataRank · unranked

0 citations

Joanne I. Hsu, Étienne De Braekeleer, Chun-Wei Chen, Tajhal D. Patel, Alejandra G. Martell +19 more

Clonal Origin of Therapy-Related Myeloid Neoplasms after Autologous Stem Cell Transplant

Blood(2024)10.1182/blood-2024-208106

N/A

0DataRank · unranked

0 citations

Koichi Saeki, Hiroshi Haeno, Chiraag D. Kapadia, Ken Furudate, Jyoti Nangalia +35 more

Hallmarks of stem cell aging

Cell stem cell(2025)10.1016/j.stem.2025.06.004

N/A

0DataRank · unranked

41 citations

Anne Brunet, Margaret A. Goodell, Thomas A. Rando

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

Cell stem cell(2025)10.1016/j.stem.2025.06.006

N/A

0DataRank · unranked

16 citations

Trisha K. Wathan, Minh Nguyen, Chen Hu, A. Rosa McDonald, Guantong Qi +24 more

Disparate leukemia mutations converge on nuclear phase-separated condensates

Cell(2025)10.1016/j.cell.2025.10.010

N/A

0DataRank · unranked

14 citations

Elmira Khabusheva, Archish Anand, Joshua Beale, Marwa Sadek, Chun‐Wei Chen +20 more

Clonal evolution of hematopoietic stem cells after autologous stem cell transplantation

Nature Genetics(2025)10.1038/s41588-025-02235-w

N/A

0DataRank · unranked

11 citations

Koichi Saeki, Hiroshi Haeno, Chiraag D. Kapadia, Ken Furudate, Jyoti Nangalia +39 more

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

Cell stem cell(2025)10.1016/j.stem.2025.07.011

N/A

0DataRank · unranked

1 citations

Trisha K. Wathan, Minh Nguyen, Chen Hu, A. Rosa McDonald, Guantong Qi +24 more

Cohesin haploinsufficiency is tolerated in Cbfb::MYH11-driven murine acute myeloid leukemia

Experimental Hematology(2025)10.1016/j.exphem.2025.105287

N/A

0DataRank · unranked

0 citations

Alexis Quezada, Kristen Kurtz, Nenggang Zhang, Josephine De La Fuente, Nesa Mercer +8 more

Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

Leukemia(2020)10.1038/s41375-020-01075-3

N/A

0DataRank · unranked

18 citations

Daniele Sorcini, Anna Guzman, Jaime M. Reyes, Arianna Stella, Andrea Marra +15 more

Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis

Blood(2020)10.1182/blood.2019003330

N/A

0DataRank · unranked

40 citations

Jianzhong Su, Xue Qing David Wang, Nagireddy Putluri, Ting Zhou, Ying Qu +8 more

Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion

Cell stem cell(2020)10.1016/j.stem.2020.06.018

N/A

0DataRank · unranked

32 citations

Jaime M. Reyes, Michael C. Gundry, Lorenzo Brunetti, Henry Lee-Six, Mia Petljak +19 more

Where There’s Smoke, There’s Fire: Inflammation Drives MDS

Trends in Immunology(2020)10.1016/j.it.2020.05.007

N/A

0DataRank · unranked

6 citations

Margaret A. Goodell, Gandhar Datar

Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.26.109579

N/A

0DataRank · unranked

0 citations

Rohit Gupta, Jaime M. Reyes, Michael C. Gundry, Geraldo Medrano, Anna Guzman +8 more

Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.

Apollo (University of Cambridge)(2021)10.17863/cam.74923

N/A

0DataRank · unranked

63 citations

Chun‐Wei Chen, Venkatasubramaniam Sundaramurthy, Mikołaj Słabicki, Dapeng Hao, Caroline J. Watson +20 more

Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome

Haematologica(2021)10.3324/haematol.2021.278990

N/A

0DataRank · unranked

25 citations

Carina Rosas, Amos Gaikwad, Geraldo Medrano, Linda Zhang, Jaime M. Reyes +19 more