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SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation

Cell stem cell(2023)10.1016/j.stem.2023.09.011Source: DataRank Database

SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation is a research paper published in Cell stem cell (2023). On theSindex it has a DataRank of 0.729. It has been cited 26 times, with 20 citing works in its 1-hop citation network.

N/A

0.729DataRank · unranked

Scored on demand from live citation data

Open Access26 citations · 20 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (33 grants)Impact (FWCI 2.76)OA: greenTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 68%Citation Network 32%

Base Score Contribution

0.494

From this paper's citation signal

Citation Network Contribution

0.235

From 14 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 20 citers.

reg-eQTL: Integrating transcription factor effects to unveil regulatory variants
The American Journal of Human Genetics20257 citations45 referencesContributes 0.046
Base-excision repair pathway regulates transcription-replication conflicts in pancreatic ductal adenocarcinoma
Cell Reports20247 citations56 referencesContributes 0.037
H2A.Z chaperones converge on E2F target genes for melanoma cell proliferation
Genes & Development202415 citations79 referencesContributes 0.035
Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex
Science202437 citations123 referencesContributes 0.030
Clonal hematopoiesis and hematological malignancy
Journal of Clinical Investigation202443 citations160 referencesContributes 0.024

Authors (21)

Linda Zhang ORCID,Ravi Dutta,Abhishek Niroula ORCID,Peter G. Miller ORCID,Christopher J. Gibson ORCID

Live enrichment

PubMed:37863054 PMC:PMC10841682 OpenAlex:https://openalex.org/W4387783930

NIH

Grant: 1P01CA265748

NIH

Grant: AG036695

NIH

Grant: CA125123

NIH

Grant: CA210827

NIH

Grant: CA237291

NIH

Grant: DK092883

NIH

Grant: K08CA252174

NIH

Grant: K08CA263183

National Heart, Lung, and Blood Institute

Grant: R01HL148050

National Heart, Lung, and Blood Institute

Grant: R01HL148565

Edward P. Evans Foundation

Grant: CA212733

Edward P. Evans Foundation

Grant: DE029633

Edward P. Evans Foundation

Grant: GM136172

Edward P. Evans Foundation

Grant: HG011875

Fondation Leducq

Grant: TNE - 18CVD04

Knut och Alice Wallenbergs Stiftelse

Grant: KAW2017.0436

Cancer Prevention and Research Institute of Texas

Grant: RP180672

NIDDK NIH HHS

Grant: R01 DK058192

NIDDK NIH HHS

Grant: R01 DK092883

NCI NIH HHS

Grant: P01 CA265748

NCI NIH HHS

Grant: R01 CA183252

NCI NIH HHS

Grant: R43 CA212733

NIA NIH HHS

Grant: P01 AG036695

NIGMS NIH HHS

Grant: R44 GM136172

NCI NIH HHS

Grant: P30 CA125123

NIDCR NIH HHS

Grant: R44 DE029633

NCI NIH HHS

Grant: R44 CA212733

NCI NIH HHS

Grant: R01 CA237291

NHGRI NIH HHS

Grant: R44 HG011875

NIDDK NIH HHS

Grant: R56 DK092883

Knut and Alice Wallenberg Foundation

Grant: unidentified

unidentified

U.S. Department of Defense

Novartis Pharmaceuticals Corporation

FWCI

2.76

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

greenLicense: Elsevier Non-Commercial

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10841682/pdf/nihms-1936686.pdf

publisherhttps://api.elsevier.com/content/article/PII:S1934590923003582?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S1934590923003582?httpAccept=text/plain

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10841682

Fields of Study

Cancer Genomics and DiagnosticsAcute Myeloid Leukemia ResearchEpigenetics and DNA Methylation03 medical and health sciences0303 health sciences

MeSH Terms

Clonal HematopoiesisAdenosine TriphosphatasesAnimalsDNA RepairHematopoiesisHumansMutationEpigenesis, GeneticAdaptor Proteins, Signal TransducingMice

Keywords

BiologyEpigeneticsHaematopoiesisStem cellGeneticsMutationDNA methylationProgenitor cellSomatic cellCell biologyCancer researchMolecular biologyGeneGene expressionDNA damageHematopoietic stem cellsChromatin remodelingLymphoidH2a.zSrcapClonal Hematopoiesis570Medical SciencesDNA Repair610Epigenesis, GeneticMiceGeneticMedical SpecialtiesMedicine and Health Sciencesand ImmunityAnimalsHumansBiological PhenomenaAdaptor Proteins, Signal TransducingAdenosine TriphosphatasesCell PhenomenaLife SciencesMedical Cell BiologyHematopoiesisMedical MicrobiologyMedical Molecular BiologyEpigenesis

Sustainable Development Goals

SDG 0: Good health and well-being

SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (21)

Funding (33 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)