Xin Xu

Computer ScienceMedicinePharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.3Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models

Scientific Reports(2020)10.1038/s41598-020-77327-0

Top 15%

1.3DataRank

Top 15%42 citations

Pranav Shah, Edward H. Kerns, Kimloan Nguyen, Kyeong Ri Yu, Md Kabir +6 more

Papers

Driven by 51 papers — median percentile 85. Top paper: “Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors”.

Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00193

N/A

3.1DataRank · unranked

90 citations

Gregory J. Tawa, Mark J. Henderson, Carina Danchik, Suiyang Liu, Pranav Shah +10 more

Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models

Scientific Reports(2020)10.1038/s41598-020-77327-0

Top 15%

1.3DataRank

Top 15%42 citations

Pranav Shah, Edward H. Kerns, Kimloan Nguyen, Kyeong Ri Yu, Md Kabir +6 more

Development of Robust Quantitative Structure-Activity Relationship Models for CYP2C9, CYP2D6, and CYP3A4 Catalysis and Inhibition

Drug Metabolism and Disposition(2021)10.1124/dmd.120.000320

N/A

1.3DataRank · unranked

40 citations

Sankalp Jain, Pranav Shah, Nao Torimoto‐Katori, Alexey Zakharov, Ðắc-Trung Nguyễn +8 more

Targeting AML-associated FLT3 mutations with a type I kinase inhibitor

Journal of Clinical Investigation(2020)10.1172/jci127907

N/A

0.557DataRank · unranked

40 citations

Katelyn Melgar, Lyndsey Bolanos, Kathleen Hueneman, Morgan M. Walker, Jian-kang Jiang +15 more

A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome

Cell Reports(2021)10.1016/j.celrep.2021.109040

N/A

0.515DataRank · unranked

30 citations

Kathleen A. Trychta, Shyh‐Ming Yang, Susanne Bäck, Adam Yasgar, Emily S. Wires +21 more

Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

Scientific Reports(2021)10.1038/s41598-021-81486-z

N/A

0.489DataRank · unranked

25 citations

Richard T. Eastman, Kathryn J. Wicht, Daniel J. Jansen, Daniel C. Talley, Benjamin A. Sigmon +25 more

Important roles of transporters in the pharmacokinetics of anti-viral nucleoside/nucleotide analogs

Expert Opinion on Drug Metabolism & Toxicology(2022)10.1080/17425255.2022.2112175

N/A

0.434DataRank · unranked

17 citations

Xin Xu, Mengbi Yang

Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors

Science Signaling(2025)10.1126/scisignal.ado2857

N/A

0.345DataRank · unranked

9 citations

Meghri Katerji, Marwa M. Afifi, Katherine M. Nyswaner, Carolyn C. Woodroofe, Zoe C. Edwards +22 more

The Brain-Penetrant Pan-ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases

Cancer Research(2025)10.1158/0008-5472.can-24-1793

N/A

0.269DataRank · unranked

5 citations

Yi‐Han Lin, Jeremy Spence, Aleksandra Głogowska, Thatchawan Thanasupawat, Jason Beiko +11 more

Galectin-1 is associated with hematopoietic cell engraftment in murine MHC-mismatched allotransplantation

Frontiers in Immunology(2024)10.3389/fimmu.2024.1411392

N/A

0.104DataRank · unranked

1 citations

Arunakumar Gangaplara, Abdoul Madjid Kone, Katherine Almengo, Mariama Djelika Kabore, Mohamed Ashraf Ali +6 more

Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo

Microorganisms(2021)10.3390/microorganisms9030566

N/A

0DataRank · unranked

21 citations

Julie Dyall, Shuang Xu, Elizabeth A. Nelson, Elena Postnikova, Janie Liang +20 more

Benserazide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease

Blood Cells Molecules and Diseases(2021)10.1016/j.bcmd.2021.102561

N/A

0DataRank · unranked

16 citations

Susan P. Perrine, Yaqin Li, Levi Makala, Hongyan Xu, Mayuko Takezaki +12 more

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells

Scientific Reports(2021)10.1038/s41598-021-90944-7

N/A

0DataRank · unranked

3 citations

Myagmarjav Dashynam, Bryan Chim, Thelma M. Escobar, Xiu-Huai Liu, Xin Hu +9 more

Discovery and Optimization of a 4-Aminopiperidine Scaffold for Inhibition of Hepatitis C Virus Assembly

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00696

N/A

0DataRank · unranked

6 citations

Daniel C. Talley, Seung Bum Park, Zongyi Hu, Andrés E. Dulcey, D. Christopher +10 more

Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs Against Ebola Virus In Vivo

Preprints.org(2021)10.20944/preprints202102.0293.v1

N/A

0DataRank · unranked

1 citations

Julie Dyall, Shuang Xu, Elizabeth A. Nelson, Elena Postnikova, Janie Liang +20 more

Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability

Bioorganic & Medicinal Chemistry(2022)10.1016/j.bmc.2021.116588

N/A

0DataRank · unranked

58 citations

Vishal B. Siramshetty, Ðắc-Trung Nguyễn, Elias Carvalho Padilha, Md Kabir, Kyeong Ri Yu +8 more

Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction

iScience(2022)10.1016/j.isci.2022.104941

N/A

0DataRank · unranked

9 citations

Joanna P. Davies, Raul Calvo, Jagruti Chaudhari, Georgia Dolios, Mercedes K. Taylor +13 more

Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment

Frontiers in Pharmacology(2022)10.3389/fphar.2022.918083

N/A

0DataRank · unranked

30 citations

Natalie R. Hagen, Elias Carvalho Padilha, Mengbi Yang, Pranav Shah, Catherine Z. Chen +6 more

Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation

Archives of Toxicology(2022)10.1007/s00204-022-03291-5

N/A

0DataRank · unranked

24 citations

Jinghua Zhao, Pranav Shah, Jameson Travers, Carleen Klumpp‐Thomas, Xin Xu +7 more

Discovery of a functionally selective ghrelin receptor (GHSR 1a ) ligand for modulating brain dopamine

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2112397119

N/A

0DataRank · unranked

18 citations

D. W. Kim, Yang Zhou, Daniel J. Jansen, Lauren M. Slosky, Nicholas Clark +13 more

Identification of Selective CYP3A7 and CYP3A4 Substrates and Inhibitors Using a High-Throughput Screening Platform

Frontiers in Pharmacology(2022)10.3389/fphar.2022.899536

N/A

0DataRank · unranked

11 citations

Elias Carvalho Padilha, Pranav Shah, Ruili Huang, Srilatha Sakamuru, Eric Gonzalez +6 more

Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2

Communications Biology(2022)10.1038/s42003-022-04143-9

N/A

0DataRank · unranked

9 citations

Kenneth J. Wilson, Courtney Myhr, Elena M. Kaftanovskaya, Mark J. Henderson, Noel Southall +13 more

Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, A Potential Oral Drug Candidate for COVID-19 Treatment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.07.478848

N/A

0DataRank · unranked

2 citations

Natalie R. Hagen, Elias Carvalho Padilha, Mengbi Yang, Pranav Shah, Catherine Z. Chen +6 more

Endocrine disruption of early uterine differentiation causes adenocarcinoma mediated by Wnt/β-catenin- and PI3K/AKT signaling

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.18.517135

N/A

0DataRank · unranked

1 citations

Wendy N. Jefferson, Brian N. Papas, Alisa A. Suen, Xin Xu, Diana V. Carreon +4 more

Developmental estrogen exposure in mice disrupts uterine epithelial cell differentiation and causes adenocarcinoma via Wnt/β-catenin and PI3K/AKT signaling

PLoS Biology(2023)10.1371/journal.pbio.3002334

N/A

0DataRank · unranked

23 citations

Wendy N. Jefferson, Brian N. Papas, Alisa A. Suen, Xin Xu, Diana V. Carreon +4 more

Automated measurement of transepithelial electrical resistance (TEER) in 96-well transwells using ECIS TEER96: Single and multiple time point assessments

SLAS TECHNOLOGY(2023)10.1016/j.slast.2023.10.008

N/A

0DataRank · unranked

22 citations

Pranav Shah, Charles R. Keese, Chris Dehnert, Michael F. Detweiler, Sam Michael +4 more

Use of physiological based pharmacokinetic modeling for cross-species prediction of pharmacokinetic and tissue distribution profiles of a novel niclosamide prodrug

Frontiers in Pharmacology(2023)10.3389/fphar.2023.1099425

N/A

0DataRank · unranked

12 citations

Amy Q. Wang, Elias Carvalho Padilha, Pranav Shah, Natalie R. Hagen, China Ryu +4 more

In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis

Biomedicine & Pharmacotherapy(2023)10.1016/j.biopha.2023.115178

N/A

0DataRank · unranked

5 citations

Mengbi Yang, Pranav Shah, Amy Q. Wang, Jianmin Duan, Joshua K. Park +9 more

Consideration of vendor-related differences in hepatic metabolic stability data to optimize early ADME screening in drug discovery

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.08.002

N/A

0DataRank · unranked

4 citations

Elias Carvalho Padilha, Rintaro Kato, Vishal B. Siramshetty, Wenwei Huang, Xin Xu +1 more

Predictive Models for Human Cytochrome P450 3A7 Selective Inhibitors and Substrates

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.2c01516

N/A

0DataRank · unranked

13 citations

Md Kabir, Srilatha Sakamuru, Pranav Shah, Elias Carvalho Padilha, Deborah K. Ngan +5 more

Low Dose Post-transplant Cyclophosphamide and Sirolimus Induce Mixed Chimerism with CTLA4-Ig or Lymphocyte Depletion in an MHC-Mismatched Murine Allotransplantation Model

Research Square(2023)10.21203/rs.3.rs-3200438/v1

N/A

0DataRank · unranked

0 citations

Mariama Djelika Kabore, Corbin McElrath, Mohamed Ashraf Ali, Katherine Almengo, Arun Gangaplara +10 more

An Orally Efficacious Thyrotropin Receptor Ligand Inhibits Growth and Metastatic Activity of Thyroid Cancers

The Journal of Clinical Endocrinology & Metabolism(2024)10.1210/clinem/dgae114

N/A

0DataRank · unranked

9 citations

Priyanka Bolel, Abhijeet Kapoor, Elena Eliseeva, Andrés E. Dulcey, Jay Scott Templin +8 more

Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice

Cell Reports(2024)10.1016/j.celrep.2024.114144

N/A

0DataRank · unranked

8 citations

Daniela Gutiérrez, Andrés E. Dulcey, Marcelo Lara, Lina Moitoso de Vargas, Yi‐Han Lin +21 more

Developing Robust Human Liver Microsomal Stability Prediction Models: Leveraging Inter-Species Correlation with Rat Data

Pharmaceutics(2024)10.3390/pharmaceutics16101257

N/A

0DataRank · unranked

6 citations

Vishal B. Siramshetty, Ewy A. Mathé, Xin Xu, Pranav Shah

Discovery of IRAK1/4/pan-FLT3 Kinase Inhibitors as Treatments for Acute Myeloid Leukemia

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00269

N/A

0DataRank · unranked

6 citations

Chris J. Finocchio, Elizabeth Croll, Gregory J. Tawa, Huixu Li, Li Ma +22 more

Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0790

N/A

0DataRank · unranked

2 citations

Raul Calvo, Anju Kumari, Rushikesh Sable, Yuhong Fang, Dingyin Tao +17 more

Repurposing of lonafarnib as a treatment for SARS-CoV-2 infection

JCI Insight(2024)10.1172/jci.insight.182704

N/A

0DataRank · unranked

1 citations

Parker Irvin, Seung Bum Park, Hannah Ivester, Inna Ricardo-Lax, Madeleine Leek +18 more

IRAK1/4/pan-FLT3 Kinase Inhibitors with Reduced hERG Block as Treatments for Acute Myeloid Leukemia

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.5c00147

N/A

0DataRank · unranked

6 citations

Chris J. Finocchio, Elizabeth Croll, Gregory J. Tawa, Mingliang Zhang, Jiangong Wang +20 more

Recipient Cells Are the Source of Hematologic Malignancies After Graft Failure and Mixed Chimerism in Adults With SCD

American Journal of Hematology(2025)10.1002/ajh.27627

N/A

0DataRank · unranked

4 citations

Emily Limerick, Matthew M. Hsieh, Kalpana Upadhyaya, Xin Xu, Oswald Phang +6 more

Pharmacokinetics and Pharmacodynamics of Nomlabofusp in Non-clinical Studies of Friedreich’s Ataxia

The AAPS Journal(2025)10.1208/s12248-025-01093-y

N/A

0DataRank · unranked

2 citations

Vanessa Ragaglia, Devin Schecter, Angela S. Miller, Eric Gonzalez, Erik Wagner +7 more

Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

Cell Discovery(2020)10.1038/s41421-020-00222-5

N/A

0DataRank · unranked

249 citations

Catherine Zhengzheng Chen, Manju Swaroop, Miao Xu, Lihui Wang, Juhyung Lee +12 more

Identifying androgen receptor antagonists using a metabolically competent high-throughput screening assay

Current Research in Toxicology(2025)10.1016/j.crtox.2025.100278

N/A

0DataRank · unranked

0 citations

Pranav Shah, Jinghua Zhao, Xin Xu, Ruili Huang, Menghang Xia +1 more

Baseline TP53 mutations in Adults with SCD developing Myeloid Malignancy following Hematopoietic Cell Transplantation

Blood(2020)10.1182/blood.2019004001

N/A

0DataRank · unranked

65 citations

Xin Xu, Irina Marić, Laura W. Dillon, Yuesheng Li, Matthew M. Hsieh +3 more

Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion

Nature Microbiology(2020)10.1038/s41564-020-0781-2

N/A

0DataRank · unranked

13 citations

Michio Imamura, Daniel C. Talley, Adam Rolt, Xin Xu, Amy Q. Wang +17 more

Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells

Scientific Reports(2020)10.1038/s41598-020-60610-5

N/A

0DataRank · unranked

11 citations

Myagmarjav Dashnyam, Bryan Chim, Thelma M. Escobar, Andrés E. Dulcey, Xin Hu +12 more

Metabolism and pharmacokinetics characterization of metarrestin in multiple species

Cancer Chemotherapy and Pharmacology(2020)10.1007/s00280-020-04042-y

N/A

0DataRank · unranked

12 citations

Pranav Shah, Amy Q. Wang, Marc Singleton, Emma Hughes, Dandan Li +7 more

Predicting liver cytosol stability of small molecules

Journal of Cheminformatics(2020)10.1186/s13321-020-00426-7

N/A

0DataRank · unranked

37 citations

Vishal B. Siramshetty, Alexey Zakharov, Noel Southall, Xin Xu, Ðắc-Trung Nguyễn +1 more

Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.14.202549

N/A

0DataRank · unranked

13 citations

Catherine Z. Chen, Manju Swaroop, Miao Xu, Lihui Wang, Juhyung Lee +12 more

Validating ADME QSAR Models Using Marketed Drugs

SLAS DISCOVERY(2021)10.1177/24725552211017520

N/A

0DataRank · unranked

45 citations

J. W. Williams, Ðắc-Trung Nguyễn, Jorge Neyra, Noel Southall, Ewy A. Mathé +3 more

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127906

N/A

0DataRank · unranked

24 citations

Miao Xu, Xin Hu, Emily M. Lee, Xiao Lü, Ruili Huang +19 more

NOX2 inhibitor GSK2795039 metabolite identification towards drug optimization

Journal of Pharmaceutical and Biomedical Analysis(2021)10.1016/j.jpba.2021.114102

N/A

0DataRank · unranked

23 citations

Pranav Shah, Ganesha Rai, Xin Xu, Elias Carvalho Padilha

Xin Xu

Indexed papers

Top data-sharing exemplar

Papers