David W. Speicher

ChemistryMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “Stromal changes in the aged lung induce an emergence from melanoma dormancy”.

Stromal changes in the aged lung induce an emergence from melanoma dormancy

Nature(2022)10.1038/s41586-022-04774-2

N/A

0.781DataRank · unranked

181 citations

Yash Chhabra, Gretchen M. Alicea, Devon A. Maranto, Stephen M. Douglass, Marie R. Webster +17 more

Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma

Nature Cancer(2021)10.1038/s43018-020-00160-x

N/A

0.725DataRank · unranked

125 citations

Takeshi Fukumoto, Jianhuang Lin, Timothy Nacarelli, Yemin Wang, Dionzie Ong +16 more

Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity

Nature Communications(2024)10.1038/s41467-024-44778-2

N/A

0.672DataRank · unranked

21 citations

Shishir M. Pant, Cecily C. Ritch, Hsin‐Yao Tang, Hongguang Shao, Harsh Dweep +14 more

HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors

Nature Communications(2022)10.1038/s41467-022-31713-6

N/A

0.668DataRank · unranked

85 citations

Bin Wu, Ting Li, Lynn A. Beer, Gaurav Sharma, Mingyue Li +23 more

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2115624119

N/A

0.515DataRank · unranked

30 citations

Michela Perego, Ekta Agarwal, Irene Bertolini, Yuan Wang, Aaron R. Goldman +16 more

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

Cancer Research(2021)10.1158/0008-5472.can-20-1496

N/A

0.489DataRank · unranked

25 citations

Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez +43 more

Regulation of EBNA1 protein stability and DNA replication activity by PLOD1 lysine hydroxylase

PLoS Pathogens(2023)10.1371/journal.ppat.1010478

N/A

0.406DataRank · unranked

14 citations

Andreas Wiedmer, Samantha S. Soldan, Leonardo Josué Castro-Muñoz, Christopher Chen, Hsin‐Yao Tang +3 more

Multiplexed serum biomarkers to discriminate nonviable and ectopic pregnancy

Fertility and Sterility(2024)10.1016/j.fertnstert.2024.04.028

N/A

0.399DataRank · unranked

9 citations

Kassie J Bollig, Suneeta Senapati, Péter Takács, Jared C. Robins, Daniel J. Haisenleder +13 more

Measuring MYC-Mediated Metabolism in Tumorigenesis

Methods in molecular biology(2021)10.1007/978-1-0716-1476-1_11

N/A

0.373DataRank · unranked

11 citations

Aaron R. Goldman, Xue Zhang, David W. Speicher, Chi V. Dang, Hsin‐Yao Tang

Proteome-defined changes in cellular pathways for decidua and trophoblast tissues associated with location and viability of early-stage pregnancy

Reproductive Biology and Endocrinology(2022)10.1186/s12958-022-00908-3

N/A

0.208DataRank · unranked

3 citations

Suneeta Senapati, Mary D. Sammel, Kurt T. Barnhart, Courtney A. Schreiber, David W. Speicher +1 more

A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor suppression

Science Advances(2021)10.1126/sciadv.abg7287

N/A

0DataRank · unranked

31 citations

Aaron R. Goldman, Hsin‐Yao Tang, Andrew V. Kossenkov, Jagadish C. Ghosh, Lucia R. Languino +4 more

Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Oncogene(2021)10.1038/s41388-021-01645-4

N/A

0DataRank · unranked

2 citations

Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert +6 more

Selective abrogation of S6K2 maps lipid homeostasis as a survival vulnerability in MAPKi-resistant NRAS MUT melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.07.438684

N/A

0DataRank · unranked

0 citations

Adam N. Guterres, Hsin‐Yi Chen, Delaine M. Zundell, Segundo Del Aguila, Patricia Reyes-Uribe +11 more

Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.15.472822

N/A

0DataRank · unranked

0 citations

Hsin‐Yao Tang, The UPenn COVID Processing Unit, David W. Speicher, Anna Kashina, Pavan Vedula

Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

Cancer Cell(2022)10.1016/j.ccell.2022.09.001

N/A

0DataRank · unranked

52 citations

Emilio Sanseviero, Douglas Marvel, Thomas Beer, Hsin‐Yao Tang, Peter Hembach +26 more

Protein Posttranslational Signatures Identified in COVID-19 Patient Plasma

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.807149

N/A

0DataRank · unranked

41 citations

Hsin‐Yao Tang, David W. Speicher, Anna Kashina, The UPenn COVID Processing Unit, Pavan Vedula

Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0535

N/A

0DataRank · unranked

35 citations

Sandra L. Harper, Amanda M. Versace, Dylan Fingerman, Gregory Schuyler Brown, Monika Bhardwaj +11 more

Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma

Oncogene(2022)10.1038/s41388-021-02154-0

N/A

0DataRank · unranked

16 citations

Vivian Chua, Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Emily Hunter +7 more

Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis

Cell Reports(2022)10.1016/j.celrep.2022.111514

N/A

0DataRank · unranked

15 citations

Judith Monzy, Bailey Aaron, Xue Zhang, Andrew V. Kossenkov, James E. Hayden +5 more

Regulation of EBNA1 Protein Stability by PLOD1 Lysine Hydroxylase

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.29.486189

N/A

0DataRank · unranked

0 citations

Andreas Wiedmer, Samantha S. Soldan, Leonardo Josué Castro-Muñoz, Hsin‐Yao Tang, David W. Speicher +2 more

Lysosomal lipid peroxidation regulates tumor immunity

Journal of Clinical Investigation(2023)10.1172/jci164596

N/A

0DataRank · unranked

56 citations

Jennifer J. Lee, Amanda M. Versace, Sandra L. Harper, Aaron R. Goldman, Mary Ann S. Crissey +11 more

Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104774

N/A

0DataRank · unranked

7 citations

Irene Bertolini, Ekta Agarwal, Jagadish C. Ghosh, Hsin‐Yao Tang, David W. Speicher +10 more

Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy

Clinical Proteomics(2023)10.1186/s12014-023-09425-w

N/A

0DataRank · unranked

7 citations

Xiangfan Yin, Jianyi Ding, Suneeta Senapati, Mary D. Sammel, Kurt T. Barnhart +4 more

Evaluation of novel biomarkers for early pregnancy outcome prediction

Biology of Reproduction(2023)10.1093/biolre/ioad162

N/A

0DataRank · unranked

3 citations

Suneeta Senapati, Péter Takács, Jared C. Robins, Daniel J. Haisenleder, Lynn A. Beer +4 more

TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation

Nature Aging(2024)10.1038/s43587-023-00564-1

N/A

0DataRank · unranked

34 citations

Bo Zhao, Martina Towers, Liping Liao, Edgar Luzete Monteiro, Xin Xu +13 more

Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0329

N/A

0DataRank · unranked

153 citations

Vito W. Rebecca, Aaron R. Goldman, Mitchell E. Fane, Stephen M. Douglass, Reeti Behera +17 more

Selective abrogation of S6K2 identifies lipid homeostasis as a survival vulnerability in MAPK inhibitor–resistant NRAS -mutant melanoma

Science Translational Medicine(2025)10.1126/scitranslmed.adp8913

N/A

0DataRank · unranked

6 citations

Adam N. Guterres, Hsin-Yi Chen, Delaine M. Zundell, Segundo W Del Aguila, Patricia Reyes-Uribe +12 more

The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells

Science Signaling(2020)10.1126/scisignal.aaz8240

N/A

0DataRank · unranked

88 citations

Ekta Agarwal, Irene Bertolini, Jae Ho Seo, M. Cecilia Caino, Jagadish C. Ghosh +8 more

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer

British Journal of Cancer(2020)10.1038/s41416-019-0711-3

N/A

0DataRank · unranked

86 citations

Caroline Perry, Adam Cohen‐Nowak, Katelyn D. Miller, Johan Vande Voorde, Qifeng Zhang +18 more

Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence

Nature Communications(2020)10.1038/s41467-020-14652-y

N/A

0DataRank · unranked

65 citations

Pingyu Liu, Takeshi Fukumoto, Timothy Nacarelli, Nail Fatkhutdinov, Shuai Wu +7 more

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Oncogene(2020)10.1038/s41388-020-01554-y

N/A

0DataRank · unranked

48 citations

Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert +6 more

129Xe NMR-Protein Sensor Reveals Cellular Ribose Concentration

Analytical Chemistry(2020)10.1021/acs.analchem.0c00967

N/A

0DataRank · unranked

13 citations

Benjamin W. Roose, Kelsey Farenhem, Zhuangyu Zhao, Madison A. Stringer, Aaron R. Goldman +3 more

A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

Cancer Research(2020)10.1158/0008-5472.can-20-0397

N/A

0DataRank · unranked

29 citations

Jessica C. Leung, Julia I-Ju Leu, Subhasree Basu, Adi Narayana Reddy Poli, Joshua L.D. Parris +16 more

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

UNC Libraries(2020)10.17615/4b7t-p380

N/A

0DataRank · unranked

3 citations

Huihua Li, David W. Speicher, Ming‐Hui Fan, Sonali Majumdar, Qiang Zhu +8 more

Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy

Breast Cancer Research(2021)10.1186/s13058-021-01391-1

N/A

0DataRank · unranked

71 citations

Min Wang, Zhao Zhang, Zhiping Li, Dong Ni, Anthony W. Ashton +4 more

A multi-omics approach to Epstein-Barr virus immortalization of B-cells reveals EBNA1 chromatin pioneering activities targeting nucleotide metabolism

PLoS Pathogens(2021)10.1371/journal.ppat.1009208

N/A

0DataRank · unranked

47 citations

Samantha S. Soldan, Chenhe Su, Andreas Wiedmer, Kyoung Jae Won, Fang Lü +8 more