🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Robert T. Manguso

Broad Institute

ORCID: 0000-0003-1336-413X

Also affiliated with Massachusetts General Hospital, Center for Cancer Research, Massachusetts Institute of Technology

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.1Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

Nucleic Acids Research(2021)10.1093/nar/gkab804

Top 7%

3.1DataRank

Top 7%135 citations

Cheryl J. Wong, Lin Yang, Nofal Ouardaoui, Dian Li, Wubing Zhang +15 more

Papers

Driven by 13 papers — median percentile 93. Top paper: “Targeting TBK1 to overcome resistance to cancer immunotherapy”.

Targeting TBK1 to overcome resistance to cancer immunotherapy

Nature(2023)10.1038/s41586-023-05704-6

N/A

4.0DataRank · unranked

171 citations

Or‐Yam Revach, Seth Anderson, Emily Kessler, Clara Wolfe, Anne Jenney +54 more

TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response

Nucleic Acids Research(2021)10.1093/nar/gkab804

Top 7%

3.1DataRank

Top 7%135 citations

Cheryl J. Wong, Lin Yang, Nofal Ouardaoui, Dian Li, Wubing Zhang +15 more

DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming

Cancer Discovery(2024)10.1158/2159-8290.cd-24-0634

N/A

0.596DataRank · unranked

16 citations

Jinkai Wan, Vajira Weeresekara, Joel Markus Vaz, Giuseppe Tarantino, Tenna Holgersen Bryde +19 more

Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening

Nature Communications(2023)10.1038/s41467-023-43790-2

N/A

0.494DataRank · unranked

26 citations

Catherine E. Koch, Yunpeng Liu-Lupo, Riley D. Hellinger, Taeyoon Kyung, Keene L. Abbott +21 more

Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants

Cell Reports Medicine(2025)10.1016/j.xcrm.2025.102210

N/A

0.382DataRank · unranked

9 citations

Angelina M. Cicerchia, Ofir Shorer, Claire A. Palin, Boryana Petrova, Seth Anderson +50 more

Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.12.579184

N/A

0.290DataRank · unranked

5 citations

Angelina M. Cicerchia, Ofir Shorer, Boryana Petrova, Seth Anderson, Joshua Park +48 more

Sialylated CD43 is a glyco-immune checkpoint for macrophage phagocytosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.05.652090

N/A

0.106DataRank · unranked

1 citations

Mounica Vallurupalli, Sarah Noel, Gail Schor, YuhJong Liu, Celeste Nobrega +29 more

ATR inhibition induces synthetic lethality in mismatch repair-deficient cells and augments immunotherapy

Genes & Development(2023)10.1101/gad.351084.123

N/A

0DataRank · unranked

32 citations

Xiaojuan Ran, Wendy Leung, Ajinkya S. Kawale, Sneha Saxena, Jian Ouyang +10 more

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity

Science(2024)10.1126/science.adl6173

N/A

0DataRank · unranked

93 citations

Hiroshi Kondo, Ashwin V. Kammula, Lei Shi, Yi Xiao, Sofiene Dhiab +33 more

Extracellular matrix proteins regulate NK cell function in peripheral tissues

Science Advances(2022)10.1126/sciadv.abk3327

N/A

0DataRank · unranked

62 citations

Maulik Vyas, Marta Requesens, Adam Langenbucher, Erik B. Schiferle, Robert T. Manguso +3 more

Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits

Cell(2025)10.1016/j.cell.2025.02.012

N/A

0DataRank · unranked

93 citations

Aiping Jiang, Serwah Danquah, Vera Valakh, Brooke Simonton, Jon Bezney +6 more

MAPK Pathway Mutations Emerge in Mutant IDH1 Inhibitor–Resistant Cholangiocarcinoma and Attenuate the IFN Response

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-25-3284

N/A

0DataRank · unranked

3 citations

Hatice D. Saatcioglu, Haley Ellis, Elia Aguado-Fraile, Qin Xu, Hiroshi Kondo +20 more

Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer

Cell Metabolism(2020)10.1016/j.cmet.2020.10.018

N/A

0DataRank · unranked

81 citations

Kevin S. Kapner, Keisuke Yamamoto, Robert S. Banh, Jasper E. Neggers, Albert S.W. Sohn +7 more