David Cooper

University of Massachusetts Chan Medical School

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 16 papers. Top paper: “Engineered ionizable lipid siRNA conjugates enhance endosomal escape but induce toxicity in vivo”.

Engineered ionizable lipid siRNA conjugates enhance endosomal escape but induce toxicity in vivo

Journal of Controlled Release(2022)10.1016/j.jconrel.2022.07.041

N/A

1.5DataRank · unranked

44 citations

Socheata Ly, Nicholas McHugh, David Cooper, Anastasia Khvorova, Annabelle Biscans

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219523120

N/A

1.2DataRank · unranked

48 citations

Minwook Shin, Ching‐Wen Chang, Daniel O’Reilly, Annabelle Biscans, Ken Yamada +41 more

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Nucleic Acids Research(2023)10.1093/nar/gkad1125

N/A

0.563DataRank · unranked

17 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +13 more

RNAi-based modulation of IFN-γ signaling in skin

Molecular Therapy(2022)10.1016/j.ymthe.2022.04.019

N/A

0.533DataRank · unranked

34 citations

Jacquelyn Sousa, Dimas Echeverria, Xueli Fan, Ying-Chao Hsueh, Khashayar Afshari +10 more

Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality for one year in an MECP2 duplication mouse model

10.1101/2025.03.26.645328

N/A

0.269DataRank · unranked

5 citations

Ashley Summers, Amy E. Clipperton-Allen, Jillian Caiazzi, Samuel R. Hildebrand, Daniel O’ Reilly +11 more

Dendritic amphiphilic siRNA: Selective albumin binding, in vivo efficacy, and low toxicity

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.102080

N/A

0DataRank · unranked

20 citations

Qi Tang, Ashley Summers, Minwook Shin, Julianna Buchwald, Rosemary Gagnon +7 more

A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.19.572404

N/A

0DataRank · unranked

4 citations

Qi Tang, Sam Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria +11 more

Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.20.533459

N/A

0DataRank · unranked

1 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +11 more

A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system

Nucleic Acids Research(2024)10.1093/nar/gkae368

N/A

0DataRank · unranked

26 citations

Qi Tang, Samuel Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria +11 more

Identification of selective and non-selective C9ORF72 targeting in vivo active siRNAs

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102291

N/A

0DataRank · unranked

9 citations

Zachary Kennedy, Bruno M.D.C. Godinho, Ashley Summers, Alexandra Weiss, Dimas Echeverria +10 more

RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.20.599943

N/A

0DataRank · unranked

6 citations

James W. Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal Ferguson, Elif O. Dogan +18 more

Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy

Nucleic Acids Research(2025)10.1093/nar/gkaf479

N/A

0DataRank · unranked

15 citations

Samuel Hildebrand, Hannah J. MacMillan, Kathryn Monopoli, Julianna Buchwald, Jacquelyn Sousa +20 more

RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

Molecular Therapy(2025)10.1016/j.ymthe.2025.05.010

N/A

0DataRank · unranked

8 citations

James W. Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal Ferguson, Elif O. Dogan +19 more

miRNA Mimic Optimization: Chemical Structure – Activity – Targetome Relationship to Engineer Selective Anti-Tumor Immunity in T cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.16.649059

N/A

0DataRank · unranked

0 citations

Tatyana Ryaykenen, Anastasia Kremer, Melanie Sauer, Samuel Jackson, David Cooper +3 more

Single-dose administration of therapeutic divalent siRNA targeting MECP2 prevents lethality for one year in an MECP2 duplication mouse model

Research Square(2025)10.21203/rs.3.rs-6465542/v1

N/A

0DataRank · unranked

0 citations

Ashley Summers, Amy E. Clipperton‐Allen, Jillian Caiazzi, Samuel Hildebrand, Daniel O’Reilly +11 more

Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin

Nature Communications(2023)10.1038/s41467-023-42714-4

N/A

0DataRank · unranked

50 citations

Hassan H. Fakih, Mohammad Zain UI Abideen, Samuel Hildebrand, Khashayar Afshari, Katherine Y. Gross +31 more